Abstract: A peritoneal dialyzer including: a catheter capable of injecting and discharging peritoneal dialysate in an abdominal cavity of a patient; a peritoneal dialysate circuit connected to the catheter; and a dialyzer provided in the peritoneal dialysate circuit, the dialyzer including a hemodialysate circuit connected so that peritoneal dialysate passing through the inside can come into contact with a hemodialysate via a hollow fiber membrane, characterized in that means capable of measuring an osmotic agent concentration in the peritoneal dialysate is provided on the peritoneal dialysate circuit on the side of the end at which the catheter is connected with respect to the dialyzer, and a mechanism for dehydrating the peritoneal dialysate according to the osmotic agent concentration measured by the aforementioned means is provided on the hemodialysate circuit, and a method of peritoneal dialysis using the peritoneal dialyzer.

Abstract: A blood purification apparatus in which the pressure in a circuit is measured by directly measuring the strain of an air trap by a strain sensor without providing a pressure measuring section in the circuit.

Abstract: A protein is efficiently nitrosylated with nitrogen monoxide by merely mixing S-nitrosoglutathione as a nitrogen monoxide donor with a protein solution containing a stabilizing agent comprising at least one compound or a combination of plural compounds selected from an N-acetylamino acid, a fatty acid, and a fatty acid salt. The method that enables efficient NO addition to a cysteine residue in un-nitrosylated protein without changing the structure of protein and hence provides NO to a living organism.

Abstract: A pre-filled syringe including a barrel 1, a base end gasket 4 which is fluid-tightly slidable in the barrel 1, a front end gasket 8 which is fluid-tightly slidable in the barrel 1, and a nozzle part 2 provided in a front end of the barrel 1, wherein the nozzle part 2 includes a front end gasket accommodation part 23 which is capable of accommodating the front end gasket 8, and liquid flow passages 21 extending in an axial direction in an inner periphery wall, through which a liquid medicine can pass when the front end gasket 23 is accommodated in the front end gasket accommodation part 23, and a sectional area of a front end of the liquid flow passages 21 is smaller than a sectional area of a base end.

Abstract: A metal needle is obtained by being dipped in a liquid selected from the group consisting of a strong acid solution of a metal, acetic acid, and butyl acetate, and then dried. Preferably, the strong acid solution of a metal to be used in the dipping treatment may be a nitric acid solution of a metal selected from the group consisting of a transition element, a lanthanoid, and an actinoid, for example, a nitric acid solution of a metal selected from the group consisting of palladium, gadolinium, germanium, beryllium, strontium, scandium, and samarium. The metal needle is a metal needle for insertion into the body that can be reliably imaged even when a general-purpose ultrasound imaging system is used, and thus is useful in confirming insertion of the needle into a blood vessel and arrival of the needle at an organ, and confirming the position of the needle when it is broken.

Abstract: Under a state where the zipper 22 of a culture bag is opened, an operator depresses the opening button 43 of an arm 40 with one finger. Consequently, a force for oscillating the arm 40 to separate a retaining portion 49 upward from the culture surface 32 around a pin 42 acts against the urging force of a leaf spring 50. Consequently, the tip 52a of an extended portion 52 ascends to a predetermined position while resisting against the urging force of the leaf spring 50. Since the lower surface 20a of the culture bag 20 is retained by a base 31 and the upper surface 20b is raised upward by the tip 52a of an extended portion 52, opening 24 of the culture bag 20 is widened. Since the width of the base 31 is larger than that of the arm 40, upper space of the culture surface 32 is not occupied by the arm 40 and a sufficiently wide work space is provided in the culture bag 20.

Abstract: An indwelling needle includes a cylindrical main body to be fixed to a fitted body, a cylindrical hub for holding a needle, and a cylindrical protective cover which surround the needle and is provided slidably along the needle. In the usage state, the hub and the needle are advanced to the tip end side with respect to the main body and the protective cover is retreated to the rear end side with respect to the main body to project a cutting edge of the needle. In the housed state, the hub is retreated to the rear end side with respect to the main body, and the protective cover is advanced to the tip end side and the cutting edge of the needle is housed within the protective cover. Erroneous sticking into medical staff is prevented, and the burden on a patient is reduced.

Abstract: Provided is a platelet-rich plasma separator which can carry out the separation of a platelet-rich plasma with a small number of gamma radiation sterilized instruments and a platelet-rich plasma separation method. The platelet-rich plasma separator comprises a first syringe and a second syringe. The first syringe comprises a first syringe cylinder provided with a first port on which a blood collection needle can be mounted, a first cap detachable from the first port, a first gasket for sealing the first syringe cylinder fluid-tightly, which first gasket is reciprocated within the first syringe cylinder, and a first plunger provided detachably on the first gasket.

Abstract: A syringe coated with a lubricant containing a silicone oil and a fine silica powder on the inner surface of the barrel of the syringe can be used for injection of a surface-active drug solution without oil droplet formation on the inner surface while preventing an increase of the gasket sliding friction.

Abstract: The stent of the present invention is a tubular member comprising annular members 1 arranged in a longitudinal direction thereof for keeping a body lumen open, and one or more connecting elements 2 for connecting longitudinally adjoining two annular members 1, 1 with one another. Each annular member 1 comprises first annular member elements 11 and second annular member elements 12 which are alternately jointed together in the circumferential direction of the annular member 1. The annular members 1 are expandable in the radial direction thereof. The stent is flexible and excellent in trackability to lumens, thus making it possible to allow the stent to pass through the three-dimensionally meandering lumens. The stent is substantially free from shortening and makes it possible to provide the stent with a lateral hole.

Abstract: The inventors perfected the present invention upon finding that a conventional fecal sampling stick is given a hollow structure that has openings a certain distant apart, permitting in aspiration through the capillary tube phenomenon. That is, the present invention is a feces collection container for collecting faeces as an analyte, which comprises a fecal sampling stick which has a holding part (11) at a base, a fecal sampling part (12) at a tip and is formed a hollow passage with openings at the tip and on the base side a predetermined distance from the tip.

Abstract: To provide a drug solution preparing kit which can be handled with ease in a substantially aseptic manner, and has no risk that a leakage of a drug solution such as a splash and a dispersion of an aerosol to an ambient environment occurs upon preparation of the drug solution There is provided a drug solution preparing kit including a pre-filled syringe and a transfusing tool, wherein the pre-filled syringe includes a sealing member which seals the tip end and can not be removed from the tip end, and that the transfusing tool includes a one-way valve which can discharge only gas from the system in an irreversible manner, and a filter which is provided so as to adjoin to the second communication channel with respect to the one-way valve.

Abstract: The prefilled syringe filled with a drug in advance, leaking of liquid from the cap is prevented, gas barrier properties are given to the whole of the barrel filled with the drug and the shoulder section so that degradation of the drug is prevented, permeation of microbial contaminants is prevented to a high extent, and efficiency of packing as a compact container can be increased. The prefilled syringe includes a guard-shaped extension projecting from the outer periphery of a shoulder section of the syringe barrel on the nozzle side, and a range from a part where a gasket of the plunger is positioned on the outer surface of the syringe barrel filled with the drug to the guard-shaped extension is covered with barrier packaging.

Abstract: The present invention provides a nerve regeneration-inducing tube in which nerve is inserted into a tubular structure and can be easily sutured and fixed without resort to any special instruments or operations, thereby allowing nerve cells to efficiently proliferate and grow in the correct direction. The nerve regeneration-inducing tube of the present invention includes: a tubular structure (A) made of a biodegradable material or a bioabsorbable material and provided inside with a matrix (B) having linear nerve-inducing channels and being made of a biodegradable material or a bioabsorbable material; and a definite space part provided at one end of the tubular structure (A).

Abstract: A system and method for measuring concentration of a constituent of a specimen are provided. The system includes an oscillator for outputting, towards the specimen, electromagnetic waves having respective different frequencies between 5 GHz and 300 GHz; a detector for detecting the electromagnetic waves that are reflected from the specimen; and a processor measuring at least one of reflection coefficient and complex permittivity of the electromagnetic waves detected and calculating the concentration of the constituent of the specimen based upon at least one of the reflection coefficient measured and the complex permittivity measured.

Abstract: A method of removing carbon monoxide from an oxygen carrier including setting a carbon monoxide bonded oxygen carrier solution across a separation membrane from an oxygen-dissolved solution; and exposing the setting part to the light and a method of removing carbon monoxide from an oxygen carrier including setting a carbon monoxide oxygen carrier solution across a hollow fiber separation membrane from an oxygen-dissolved solution; and exposing the setting part to light.