Patents Assigned to Nipro Corporation
  • Patent number: 11780759
    Abstract: There is provided a means which carries out a fire-blast treating effectively upon removing a deteriorated region caused by processing in a process of producing a glass vessel. In a process of producing a glass vessel by fire-blast treating an internal surface 10 of a preform of the glass vessel with a flame from a burner 30 so as to produce the glass vessel, said fire-blast treating is carried out such that a temperature of an outer surface portion of the preform which portion is opposed to the deteriorated region caused by processing is between 650° C. and 800° C. when the flame is scanned along the internal surface of the preform toward an opening of the preform.
    Type: Grant
    Filed: April 21, 2016
    Date of Patent: October 10, 2023
    Assignee: NIPRO CORPORATION
    Inventor: Yoshio Inoue
  • Patent number: 11697004
    Abstract: To provide a new balloon catheter enabling formation of, with high dimensional accuracy and excellent shape adaptability with respect to a balloon, an additional structure such as a blade and a reinforcement member to be additionally provided to the balloon. In this balloon catheter 10 provided with an expandable/contractible balloon 14 on the distal end side of a catheter 12, an additional structure 36 having a prescribed pattern is formed through electroforming or the like directly onto an inner circumferential surface 34 and/or an outer circumferential surface 82 of the balloon 14.
    Type: Grant
    Filed: February 18, 2020
    Date of Patent: July 11, 2023
    Assignee: NIPRO CORPORATION
    Inventors: Yoshihiko Sano, Yasushi Ooyama, Katsuhiro Hiejima
  • Publication number: 20230211057
    Abstract: There is provided a technique for detecting leakage in extracorporeal blood circulation while suppressing increased cost in a dialysis device. A dialysis device includes an artery-side blood circuit, a dialyzer, and a vein-side blood circuit. The dialysis device detects an abnormality based on a difference between theoretical value and measured value of a blood concentration in the vein-side blood circuit. The theoretical value of the blood concentration in the vein-side blood circuit is specified based on blood concentration and blood flow rate in the artery-side blood circuit and a water removal rate in the dialyzer.
    Type: Application
    Filed: May 18, 2021
    Publication date: July 6, 2023
    Applicant: NIPRO CORPORATION
    Inventors: Shota NAKAMURA, Yoichi KAMOSHITA, Yukio WASHIO
  • Patent number: 11690572
    Abstract: A flush device including: a first housing provided with a first flow path; a second housing provided with a second flow path, the second housing being coupled to the first housing; a flow control device including a protrusion and a through hole connecting the first flow path to the second flow path in fluid communication; and an elastic member provided around the base of the flow control device to seal off a space between the first and the second flow paths. The elastic member is deformed to further connect the first and second flow paths in fluid communication. The first housing has an inner periphery provided with fitting receiving portions each being fitted to each of the fitting projections of the protrusion. According to this structure, the flush device can discharge a chemical liquid at a flow rate close to a defined amount.
    Type: Grant
    Filed: September 11, 2018
    Date of Patent: July 4, 2023
    Assignee: NIPRO Corporation
    Inventors: Yasushi Matsumoto, Kuniaki Matsumoto
  • Patent number: 11690961
    Abstract: A needle cap and a dialysis circuit priming device with increased safety and convenience in the cleaning and priming of a blood circuit are provided. According to the present invention, a needle cap is provided including two needle connecting parts, and a flow path connecting the two needle connecting parts. A dialysis circuit priming device is also provided including two needles, two needle connecting parts each arranged with the two needles respectively, and a flow path for connecting the two needle connecting parts.
    Type: Grant
    Filed: October 7, 2019
    Date of Patent: July 4, 2023
    Assignees: ARTISAN LAB CO., LTD., NIPRO CORPORATION
    Inventors: Kazuhiko Shibata, Hiroyuki Nakagami, Tatsuya Kudo, Naoya Kataoka
  • Publication number: 20230201772
    Abstract: The present invention relates to a separation device or system using a separation membrane, as a method of separating impurity ions other than hypochlorous acid from an aqueous solution containing hypochlorous acid as a main component, and provides a solution containing hypochlorous acid as a main component, having more excellent storage stability.
    Type: Application
    Filed: May 21, 2021
    Publication date: June 29, 2023
    Applicants: NIPRO CORPORATION, Health Support SANRI Corporation
    Inventors: Yoshihiko SANO, Tadao SHIOYAMA, Yoshinaga SUDO
  • Publication number: 20230193206
    Abstract: Provided is a method for producing serum that exhibits improved cell proliferation activity. A method for producing serum for culturing mammalian cells, comprising: maintaining blood collected from a first mammal at a temperature between 15° C. and 25° C. for up to 48 hours and preparing serum from the blood.
    Type: Application
    Filed: December 25, 2020
    Publication date: June 22, 2023
    Applicants: SAPPORO MEDICAL UNIVERSITY, NIPRO CORPORATION
    Inventors: Osamu Honmou, Yoshihiro Yoshikawa, Takanori Sambuichi, Naomi Morikawa, Kazunari Abe
  • Patent number: 11666601
    Abstract: The present invention relates to a synapse formation promoter and a brain plasticity promoter comprising CD24-negative mesenchymal stem cells prepared from a patient's own bone marrow aspirate and treatment of dementia, chronic-phase cerebral infarction, chronic-phase spinal cord injury, mental diseases, and the like using the synapse formation promoter and brain plasticity promoter.
    Type: Grant
    Filed: April 26, 2017
    Date of Patent: June 6, 2023
    Assignees: Sapporo Medical University, Nipro Corporation
    Inventors: Osamu Honmou, Masanori Sasaki, Rie Maezawa, Shinichi Oka, Yuko Sasaki, Masahito Nakazaki, Toshihiko Yamashita
  • Publication number: 20230158251
    Abstract: An indwelling needle having: inner needle that punctures living body; outer needle inserted into living body with inner needle as inner needle penetrates outer needle and punctures living body; main body disposed along axis of inner needle; branch part that branches from main body. Indwelling needle includes: outer needle hub has passage in communication with interior of outer needle; elastic member disposed within outer needle hub, penetrated by inner needle, and flexible solid part that blocks fluid flow to proximal end side of main body when inner body is removed; holder attached to proximal end of elastic member. Elastic member forms at least part of passage that allows communication between interior of outer needle and branch part, has end surface inclined relative to axial direction. Outer needle hub has guide part engaged with elastic member or holder and guides rotation direction of elastic member around axis to certain direction.
    Type: Application
    Filed: March 30, 2021
    Publication date: May 25, 2023
    Applicant: NIPRO CORPORATION
    Inventors: Takako MIYAKE, Hiroki YOKOTA
  • Publication number: 20230159233
    Abstract: A package includes a first side, a second side and a hinge. As the first side and the second side pivot around the hinge, the first side and the second side make transition between a closed state and an opened state. The first side includes a first fitting portion in a projecting shape, a rigid portion provided in a partial section on a line that goes around the first fitting portion, and a first weak portion provided in a remaining section on the line that goes around the first fitting portion and being lower in rigidity than the rigid portion. The second side includes a second fitting portion in a recessed shape and fitted to the first fitting portion in the closed state and a second weak portion provided on a line that goes around the second fitting portion and being lower in rigidity than the rigid portion.
    Type: Application
    Filed: September 27, 2019
    Publication date: May 25, 2023
    Applicant: NIPRO CORPORATION
    Inventor: Mitsuru HASEGAWA
  • Publication number: 20230158202
    Abstract: Provided is a local hemostasis material, which exerts little influence on the human body, is inexpensive, and exerts a good hemostatic. The local hemostasis material comprises a base material having a first major surface and a layer including cationized cellulose on the first major surface, wherein the layer including cationized cellulose has a thickness of no less than 6.7 µm.
    Type: Application
    Filed: December 25, 2020
    Publication date: May 25, 2023
    Applicants: ARTISAN LAB CO., LTD., NIPRO CORPORATION
    Inventors: Kazuhiko Shibata, Noriko Hattori, Hiroshi Yoshida
  • Patent number: 11650166
    Abstract: The present invention provides a method for evaluating a processing deterioration level of a medical glass container, including (a) a step of imaging a surface of a medical glass container molded from a borosilicate glass tube to obtain an image, and (b) a step of analyzing a contrast of the image. The method is particularly useful to evaluate the amount of alkali substances which are deposited on the inner side surface of a medical glass container.
    Type: Grant
    Filed: May 30, 2018
    Date of Patent: May 16, 2023
    Assignee: NIPRO CORPORATION
    Inventor: Dave Lisman
  • Patent number: 11638791
    Abstract: A syringe type ejection device capable of reducing an amount of residual liquid is provided. A syringe type ejection device includes: a barrel; a nozzle disposed to face the barrel; and a core inserted in the nozzle, the barrel having a large-diameter portion provided with a discharge space for discharging liquid, the nozzle being provided with a holding space for holding the core, the holding space being in communication with the discharge space, and the core being inserted in the discharge space.
    Type: Grant
    Filed: March 29, 2018
    Date of Patent: May 2, 2023
    Assignee: NIPRO CORPORATION
    Inventors: Yukihiro Yabe, Teruhisa Hirobe
  • Patent number: 11628241
    Abstract: A blood purification apparatus that includes a blood purifier, a vascular access flow path, a cleaning solution flow path, and a drainage flow path. The blood purifier has an inner portion divided by a semi-permeable membrane into a first portion and a second portion. The vascular access flow path is connected to the blood purifier and is in communication with the first portion. The cleaning solution flow path is connected to the blood purifier and is in communication with the first portion. The drainage flow path is connected to the blood purifier and is in communication with the second portion. The cleaning solution flow path is provided with a blood pump capable of bidirectionally feeding a fluid. An open-close valve is provided in each of the vascular access flow path and the drainage flow path.
    Type: Grant
    Filed: June 22, 2018
    Date of Patent: April 18, 2023
    Assignee: NIPRO CORPORATION
    Inventors: Mitsutaka Ueda, Hidetoshi Saio
  • Publication number: 20230001102
    Abstract: A safety mechanism syringe includes a syringe, a needle, a holder, and a needle cover displaceable relatively with respect to the syringe along an axial direction of the syringe from a use position toward a protection position. The holder includes a locking portion. At least one member of the holder and the needle cover includes a protruding portion that protrudes toward the other member, and the other member includes a restriction portion that abuts on the protruding portion to restrict relative displacement of the needle cover with respect to the syringe along the axial direction of the syringe from the protection position toward the use position.
    Type: Application
    Filed: December 9, 2020
    Publication date: January 5, 2023
    Applicant: NIPRO CORPORATION
    Inventor: Yukihiro YABE
  • Patent number: 11542480
    Abstract: A mutant glycine oxidase is obtained by substituting at least one wild-type amino acid sequence derived from thermophilic bacteria belonging to the family Bacillus with another amino acid, and has the following enzyme properties. Molecular weight: 40,000±2,000 daltons by SDS-PAGE. Optimum temperature: 45° C. under the condition of pH 8.5 in presence of pyrophosphate. Optimum pH: pH 8.0 under the condition of 37° C. in presence of pyrophosphate. Thermal stability: Stable up to 70° C. under the condition of pH 8.5 while retaining for 1 hour in presence of pyrophosphate. pH Stability: Stable in the range of pH 5.5 to 10.0 under the condition of 4° C. while retaining for 24 hours in presence of pyrophosphate. Specific activity: 1.2 units/mg or more. Kinetic constant Km: 0.2 mM or less.
    Type: Grant
    Filed: September 10, 2018
    Date of Patent: January 3, 2023
    Assignee: NIPRO CORPORATION
    Inventors: Takashi Kimura, Yasushi Tani
  • Patent number: 11529165
    Abstract: To provide a catheter having a simple structure capable of excising an atheroma in a blood vessel and capable of obtaining ultrasonic images of a blood vessel. [Solution] A catheter 10 has a shaft 11 having an opening 20 in a part of the side wall on the distal end side, a cutter 12 which is located in the vicinity of the opening 20 in the internal space of the shaft 11 and which can move in the axial direction 101 of the shaft 11, a balloon 23 which is disposed on the side opposite to the opening 20 with respect to the axis of the shaft 11 and which outwardly expands from the side wall of the shaft 11, and a phased array ultrasound probe 17 disposed along the circumferential direction 102 of the outer peripheral surface of the side wall in the vicinity of the opening 20 at least on the same side as the side where the opening 20 is provided with respect to the axis of the shaft 11.
    Type: Grant
    Filed: August 2, 2019
    Date of Patent: December 20, 2022
    Assignee: Nipro Corporation
    Inventors: Katsuya Miyagawa, Misa Matsumoto, Tomonori Nakamura
  • Patent number: 11529474
    Abstract: A valved needle assembly including a needle hub provided to a proximal end side of a hollow needle, and a valve member incorporated therein for blocking communication with the hollow needle. A protrusion protrudes from a distal end side toward a proximal end side inside the needle hub and the valve member blocks the proximal end side of the protrusion inside the needle hub. A central valve part of the valve member having a slit moves toward the protrusion such that the slit is opened and placed in communication by the protrusion. The central valve part includes a distal end tubular part and a proximal end tubular part extending from its outer circumferential portion toward the distal end side and the proximal end side respectively.
    Type: Grant
    Filed: May 8, 2018
    Date of Patent: December 20, 2022
    Assignee: NIPRO CORPORATION
    Inventors: Hiroyuki Nakagami, Shingo Sakamoto
  • Patent number: D987820
    Type: Grant
    Filed: July 19, 2021
    Date of Patent: May 30, 2023
    Assignee: Nipro Corporation
    Inventor: Yukihiro Yabe
  • Patent number: D987824
    Type: Grant
    Filed: June 8, 2021
    Date of Patent: May 30, 2023
    Assignee: Nipro Corporation
    Inventors: Misa Matsumoto, Katsuya Miyagawa, Tomoe Morita