Abstract: A multilayer culture vessel, comprising a culture vessel part and a reservoir part attached to the culture vessel part, wherein the culture vessel part comprises at least two culture trays that are stacked; the reservoir part comprises a surrounding wall defining an internal space and a port communicating with the internal space; the surrounding wall comprises a first surrounding wall part provided with the port and a second surrounding wall part facing the first surrounding wall part; the culture vessel part has openings communicating individual culture trays of the at least two culture trays with the internal space of the reservoir part; and the openings of the culture vessel part extend toward a first abutting portion that the first surrounding wall part abuts on the culture vessel part from a second abutting portion that the second surrounding wall part abuts on the culture vessel part.

Abstract: The present disclosure provides a method for detecting Alzheimer's cognitive impairment or mild cognitive impairment, comprising: measuring an amount of homocysteic acid in a biological sample from a subject who suffers or possibly suffers from a neurological disease, and detecting Alzheimer's cognitive impairment or mild cognitive impairment based on the measured amount of the homocysteic acid.

Abstract: A stent having a line-shaped body that extends helically in a circumferential direction while reciprocating in an axial direction by continuously alternating straight parts and curved parts, wherein the plurality of straight parts in the line-shaped body have a substantially constant thickness throughout the entire stent, and a certain number of the plurality of curved parts in the line-shaped body have different thicknesses.

Abstract: An artificial joint is characterized by: having a first member including a caput part on which a prescribed curved surface is formed, and a second member including a fossa part having a surface which abuts the prescribed curved surface of the caput part; the second member being rotatable in a flexing direction of a joint with a prescribed point on the caput part being the center of rotation; and the prescribed curved surface of the caput part being defined by a curve which depicts a convex arc toward the side abutting the fossa part when the caput part is viewed from the axial direction of the rotation, and in which, when two arbitrary points are taken on the curve, the radius of curvature of the point positioned further toward the flexing side of the joint on the curve is smaller than the radius of curvature of the other point.

Abstract: A storage case with a biomedical electrode pad for storing a biological signal processing circuit unit for processing an biological electrical signal which has been detected by the biomedical electrode pad, wherein a case body thereof has a storage area for the biological signal processing circuit unit, the storage area being provided in an openable and closable manner, and the biological signal processing circuit unit is detachable with respect to the storage area.

Abstract: Problem to be Solved Provided is a method for manufacturing a pharmaceutical preparation, which safely and simply enables uniformization of contents of a small amount of a drug. [Solution] The method for manufacturing the pharmaceutical preparation includes: using a liquid for dispensing, the liquid containing a drug; and a first application step of applying the drug to a surface of a tablet or a capsule by a dispensing method. In addition, a pharmaceutical preparation according to the present invention includes: a base; and a drug which is applied to a surface of the base by a dispensing method, and the base is a tablet or a capsule.

Abstract: An object is to provide a blood purifying device and an access flow rate measuring method enabling easy and accurate measurement of an access flow rate of an access vessel. A blood purifying device includes a flow rate calculating unit calculating the access flow rate of an access vessel based on an initial blood indicator for blood distributed through a vein side circuit and flowing through the access vessel of a patient, the flow rate distributed through measuring means when a pump is reversed to cause the priming solution to flow out from an artery side circuit, and a blood indicator for the blood diluted with the priming solution which is obtained when the pump is reversed to dilute, with the priming solution, the blood distributed through the vein side circuit.

Abstract: The present invention provides a needle tip protector of a novel structure for an indwelling needle, which enables improvements in safety, etc. as compared with conventional needle tip protectors. A needle tip protector 10 for an indwelling needle includes a tubular peripheral wall 58, and is externally attached over a needle hub 22 of an indwelling needle 16 and moved toward a needle tip 14 side so as to cover the needle tip 14. Detents 74, 74, which are to be detained with the needle hub 22 at a position in a movement of the protector toward the needle tip 14 side of the indwelling needle 16 so as to inhibit backward movement of the protector to the proximal end side of the indwelling needle 16 and to prevent the needle tip 14 from being reexposed, are formed within an inside enclosed by the peripheral wall 58, and are integrally molded with the peripheral wall 58.

Abstract: The present invention relates to a pharmaceutical composition for treating amyotrophic lateral sclerosis. More specifically, the present invention relates to a pharmaceutical composition for treating amyotrophic lateral sclerosis, wherein the pharmaceutical composition comprises mesenchymal stem cells and is intravenously administered.

Abstract: The present invention relates to a pharmaceutical composition containing mesenchymal stem cells administered to a patient subjected to stenting. The present invention relates specifically to: a pharmaceutical composition for repairing and regenerating tissue, comprising mesenchymal stem cells, wherein the pharmaceutical composition is administered to a patient subjected to stenting; and the prevention of in-stent neointimal hyperplasia or in-stent restenosis with the pharmaceutical composition.

Abstract: A puncturing tool for small animals which has a novel structure, facilitates confirmation of the connection state of a capillary tube, and can prevent inadvertent detachment of the capillary tube. A puncturing tool for small animals includes a connecting part for a capillary tube on the proximal end side of a hollow needle, wherein the connecting part has a tapered peripheral wall that expanding and extending in a direction away from the hollow needle, and a tapered peripheral wall has an elastic fitting part, through which the capillary tube is inserted, projecting inward from a middle portion of the tapered peripheral wall in the length direction thereof.

Abstract: A syringe cap assembly includes a lock collar to be attached to an ejection port at a proximal end of the syringe, and a plastic cap screwed and thereby tightened into the lock collar. An external surface of the lock collar has projecting ribs that are each extended in an axial direction and are arranged in a circumferential direction to define recessed grooves, each recessed groove is extended in the axial direction and located between adjacent projecting ribs of the projecting ribs, and the adjacent projecting ribs are adjacent to each other in the circumferential direction. A bottom of an external surface of the plastic cap includes a protrusion extending in a direction toward the lock collar. At a stage where a tightening rotation of the plastic cap implemented by screwing the plastic cap into the lock collar is completed, the protrusion is located in the recessed groove between the adjacent projecting ribs.

Abstract: A support catheter is used together with a guiding catheter in which a treatment catheter is inserted, the guiding catheter guiding the treatment catheter in a blood vessel, the support catheter being inserted in the guiding catheter from a proximal-side opening of the guiding catheter and having such a length that the support catheter protrudes from a distal-side opening of the guiding catheter, the support catheter guiding a distal end portion of the treatment catheter to a treatment site. The support catheter includes: a distal shaft forming a distal-side portion of the support catheter, the distal shaft having a tubular shape such that the treatment catheter is insertable in the distal shaft; and a proximal shaft forming a proximal-side portion of the support catheter. The proximal shaft is joined to a proximal-side portion of the distal shaft by a modified polyolefin-based adhesive.

Abstract: Disclosed herein is a blood pressure measuring device including: a pressure measuring tool 110; a fastening member 120 configured to fasten the pressure measuring tool 110 in rest position onto a skin region covering an anastomotic region of a shunt blood vessel 201; and a control circuit 130 configured to receive an input signal from the pressure measuring tool 110 and to process the input signal to calculate a pressure inside the anastomotic region of the shunt blood vessel 201.

Abstract: This needle assembly is provided with a needle having a needle tip, a needle hub, and a protector. The protector is displaceable between a non-protection position at which the needle is exposed and a protection position at which the needle tip is covered; has an opening formed elongated to match the needle, and includes a main body and a claw-like portion. The needle enters the main body from the opening to cover the needle tip when the protector is displaced to the protection position. The claw-like portion is bent by the needle when the protector is displaced to the protection position, allows the needle to advance into the main body, and is elastically restored to lock the needle when the needle enters the main body. The claw-like portion projects obliquely from the main body, extends across the opening in the width direction, and extends in the longitudinal direction.