Abstract: Provided is a catheter with a novel structure which is able to allow its distal end portion to deform to curve more effectively in response to an operation from an outside. In a catheter 10, a control lumen 24 extending in a lengthwise direction is provided to an elongated shaft member 33, a control wire 54 is inserted through the control lumen 24, a fixing part 57 to which a distal end of the control wire 54 is fixed is provided to the shaft member 33, and an exposed part 60 is provided to a distal end portion of the control wire 54 over a predetermined length so as to be exposed through a window part 58 provided to a peripheral wall 28 of the control lumen 24 to a separate internal space 12 in the shaft member 33.

Abstract: Provided is a stent having a novel structure, the stem simultaneously having both the stability of shape against the action of external force, such as compression force, tensile force, or torsional force, and high flexibility in the direction of twisting of the stem. Connection groups are provided at three or more positions set at circumferentially equally-spaced intervals, the connection groups each including connection sections which are disposed circumferentially close to each other between axially adjacent tubular divided bodies. The connection groups on both sides axially of each of the tubular divided bodies are provided at positions circumferentially offset from each other while at least one turning portion is present between the connection groups.

Abstract: It is intended to quantitatively evaluate deterioration in brain function associated with a disease such as dementia, with a high degree of accuracy by a simplified method using signals acquired from a few sensors arranged on the scalp.

Abstract: A method of manufacturing a PTP sheet for pharmaceutical drug packaging from which a solid pharmaceutical drug is easily taken out and in which a pocket portion is hard to be accidentally damaged. The PTP sheet has a first sheet from which a pocket portion capable of housing a solid pharmaceutical drug protrudes to the side of an upper surface and a second sheet which is stuck to a lower surface of the first sheet and which closes an opening of the pocket portion. The pocket portion has a peripheral wall portion having a peripheral surface continuous with the upper surface and a top portion having a top surface continuous with the peripheral surface of the peripheral wall portion. A wall thickness of the peripheral wall portion is smaller than a wall thickness of the top portion.

Abstract: To provide a catheter having a simple structure capable of excising an atheroma in a blood vessel and capable of obtaining ultrasonic images of a blood vessel. [Solution] A catheter 10 has a shaft 11 having an opening 20 in a part of the side wall on the distal end side, a cutter 12 which is located in the vicinity of the opening 20 in the internal space of the shaft 11 and which can move in the axial direction 101 of the shaft 11, a balloon 23 which is disposed on the side opposite to the opening 20 with respect to the axis of the shaft 11 and which outwardly expands from the side wall of the shaft 11, and a phased array ultrasound probe 17 disposed along the circumferential direction 102 of the outer peripheral surface of the side wall in the vicinity of the opening 20 at least on the same side as the side where the opening 20 is provided with respect to the axis of the shaft 11.

Abstract: A method of determining an ESA dose, which allows a hemoglobin concentration in the blood to be stably maintained at a target value, and which can decrease a range of fluctuation of the hemoglobin concentration with respect to the target value. The method comprises the steps of: setting the target value of the hemoglobin concentration in the blood; calculating a target value of a hemoglobin production rate which allows the hemoglobin concentration to reach the target value; calculating a serum ESA concentration which allows the hemoglobin production rate to reach the target value, from a relationship between the hemoglobin production rate and the ESA concentration; and calculating an amount of administration of an ESA which gives the serum ESA concentration, from a relationship between the ESA concentration and the amount of administration of the ESA, to determine an ESA dose which allows the hemoglobin concentration to reach the target value.

Abstract: A PTP sheet for pharmaceutical packaging has a first sheet in which pockets each capable of housing a solid pharmaceutical are projected to the side of a first surface which is one of a back surface and a front surface and a second sheet which is pasted to a second surface opposite to the first surface in the first sheet and covers an opening of the pocket. The second sheet has a first region having mesh-shaped grooves having a first depth in a third surface opposite to the surface to be pasted to the second surface and a second region having mesh-shaped grooves having a second depth smaller than the first depth or not having a groove.

Abstract: [Object] To provide a catheter having a simple structure capable of excising an atheroma in a blood vessel and capable of obtaining ultrasonic images of a blood vessel. [Solution] A catheter 10 has a shaft 11 having an opening 20 in a part of the side wall on the distal end side, a cutter 12 which is located in the vicinity of the opening 20 in the internal space of the shaft 11 and which can move in the axial direction 101 of the shaft 11, a balloon 23 which is disposed on the side opposite to the opening 20 with respect to the axis of the shaft 11 and which outwardly expands from the side wall of the shaft 11, and a phased array ultrasound probe 17 disposed along the circumferential direction 102 of the outer peripheral surface of the side wall in the vicinity of the opening 20 at least on the same side as the side where the opening 20 is provided with respect to the axis of the shaft 11.

Abstract: A valved needle assembly includes a connector having an inner hole, a pipe body fixed to a tip end of the connector, a valve body, and an assembly part in which an insertion part provided to one of the connector and the pipe body is inserted into another such that the connector is disposed within or about the pipe body. A locking protrusion and a locking part are provided to superposed faces of the connector and the pipe body in the assembly part for preventing the insertion part from dislodgment by mutual lock, and an inclined guide surface for guiding the locking protrusion is formed on a tip end in a direction of assembly of the connector or the pipe body to which the locking part is provided. The valve body is incorporated by being mated with the connector and the pipe body.

Abstract: A PTP sheet for pharmaceutical drug packaging from which a solid pharmaceutical drug is easily taken out and in which a pocket portion is hard to be accidentally damaged. A PTP sheet has a first sheet from which a pocket portion capable of housing a solid pharmaceutical drug protrudes to the side of an upper surface and a second sheet which is stuck to a lower surface of the first sheet and which closes an opening of the pocket portion. The pocket portion has a peripheral wall portion having a peripheral surface continuous with the upper surface and a top portion having a top surface continuous with the peripheral surface of the peripheral wall portion. A wall thickness of the peripheral wall portion is smaller than a wall thickness of the top portion.

Abstract: An applicator includes: a liquid medicine container having an opening, and a brush member arranged adjacently to the liquid medicine container to cover the opening. The brush member is made up of a plurality of fibers that are bundled together. The brush member has a tubular shape in a root portion located adjacently to the liquid medicine container, tapers from the root portion toward a top end portion located opposite to the liquid medicine container, and has a wedge shape in the top end portion.

Abstract: In an indwelling needle assembly, a safety mechanism part is provided with an outer-needle-hub engaging part to be engaged with an outer needle hub, and an engaging-part opposing wall. Relative rotation of the outer-needle-hub engaging part and the engaging-part opposing wall is restricted, and at least one of the outer-needle-hub engaging part and the engaging-part opposing wall displaces integrally with urging parts. When an inner needle is pulled out of the outer needle hub, a block part engaged with the inner needle through an inner-needle engaging part is moved relative to the urging parts and forced to a non-contact state, and the urging parts displace in a direction approaching the inner needle, thereby preventing a needle tip of the inner needle from protruding from the safety mechanism part and releasing engagement of the outer needle hub with the safety mechanism part.

Abstract: A balloon catheter (10) has a shaft (12) having an elastically expandable balloon (11) on the distal end side and space provided inside and allowing a fluid to flow into and flow out the balloon (11), a heat generating member (22) provided in the internal space of the balloon (11), and optical fibers (20A, 20B) which are extended up to the internal space of the balloon (11) along the shaft (12) and emit light beams input into the proximal end to the heat generating member (22) from the distal end.

Abstract: A standard reagent kit for analysis of a dialysis fluid includes (1) a vial A filled with an aqueous solution A including an electrolyte component capable of reacting with carbonate ion to form a precipitate, and (2) a vial B filled with an aqueous solution B including at least either one of bicarbonate ion and carbonate ion. At least the vial B is a water-repellent resin vial, and provides a standard reagent for analysis of a dialysis fluid. Precipitation is prevented for a long period of time, a change of a content of bicarbonate ion is controlled, a complicated procedure is not required for preparation thereof, handling thereof is easy, and checking of a dialysis fluid after preparation thereof can be performed easily and accurately at medical treatment site.

Abstract: Provided is a specimen collection tip having a novel structure, with which it is possible to collect a trace amount of a specimen with good quantitative precision. Also provided is a specimen preparation container having a novel structure, with which it is possible to dilute and prepare the specimen collected with the specimen collection tip with good quantitative precision. A specimen collection tip 10, wherein a specimen holding region 12 having a predetermined volume is provided inside the specimen collection tip 10, and in a distal end portion extending from a support part 15, there is formed a specimen collection hole 22 and an air vent hole 24 placing the specimen holding region 12 in communication with a surface 23. Also, a specimen preparation container 26 with a cap 30, wherein the specimen collection tip 10 is attached to the cap 30 at the support part 15.

Abstract: The present invention relates to a life extension agent containing CD24-negative mesenchymal stem cells and the treatment of dementia, cerebral infarction, spinal cord injury and the like using the life extension agent.

Abstract: In a blood purification device containing a blood purifier, a blood circuit, a blood pump, and a dialysate line having a fresh dialysate supply line and a used dialysate discharge line, a pair of plunger pumps are disposed in the dialysate line. The pair of plunger pumps are synchronized so that delivery of a fresh dialysate from one plunger pump and suction of a used dialysate into the other plunger pump simultaneously occur and the stroke of at least one of the pair of plunger pumps is made variable.

Abstract: A filter device has a catheter having a lumen, a shaft extended in the longitudinal direction from the lumen, and a filter capturing an embolus. The filter is connected to the shaft through a slide ring at the distal end thereof. The shaft is inserted into and passed through the ring. The ring is rotatable with respect to the shaft and slidable in the longitudinal direction. When the filter is expanded in a blood vessel, the ring slides on the shaft. The filter is connected to the shaft through another ring on the peripheral edge of an opening. The shaft is inserted into and passed through the ring. The ring is rotatable with respect to the shaft. The ring is held between a pair of stoppers fixed onto the shaft. Therefore, the movement of the ring in the longitudinal direction with respect to the shaft is prevented.

Abstract: There is provided means with which, during frozen storage of a biological sample or a drug, the biological sample or drug stored inside a frozen storage container is not susceptible to contamination. A frozen storage container 10 includes a container body 11 with an internal space 13, and a partition wall 12 which divides the internal space 13 of the container body 11 at least into a first space 14 and a second space 15. In the container body 11, the first space 14 is liquid-tightly sealed, the second space 15 has an opening 22 which is in communication with the outside, and the second space 15 is liquid-tightly sealable by welding the container body 11.