Abstract: An oral solid preparation including a base compound and a powdery or granular additive colored with a colorant and a method of manufacturing an oral solid preparation including the steps of: coloring an additive with a colorant, mixing the resultant additive with a base compound, and tableting the mixture.

Abstract: A package for a cryopreservation container including at least an adhesive fluoropolymer film. The package for a cryopreservation container makes it possible to store blood, rare cells and vital tissues in a very low temperature environment without any damage to the container. Further, the sealing strength resulting from heat sealing after placing a cryopreservation container in the packages is very good. Therefore, liquid nitrogen can be inhibited from entering the inside and thus contamination with bacteria, viruses or the like contained in liquid nitrogen can be avoided and the package can be prevented from being broken by expansion of intruder liquid nitrogen on the occasion of thawing. Also disclosed is a method for packaging a cryopreservation container and a method of producing a package for a cryopreservation container.

Abstract: The kit for suppressing drug craving K is used by connecting an instrument for suppressing drug craving 1 to a syringe 2 and the instrument for suppressing drug craving 1 has a cylindrical housing 11, a pouch 12 provided in the housing and containing pseudo-blood B and a connecting member 13 with which the distal end of a syringe is coupled and which cause the syringe to communicate with the interior of the pouch. When the syringe accommodating pseudo-drug M is connected to the instrument and the plunger is moved forward (pseudo-priming), the pseudo-drug M flows into a pouch and the pouch inflates (FIG. 2(b)), and if the plunger 4 is pulled back from this condition, the pouch 12 deflates and the pseudo-blood B flows back from the pouch 12 to the syringe 2 (flashback) (FIG. 2(C)).

Abstract: A label enables a user to recognize information necessary when using a medicine bag in a reliable fashion. The label includes a base part indicating thereon basic information including at least information on ingredients of medicines accommodated in a medicine bag and a detachable part detachably joined to the base part. The detachable part is so shaped as to be attachable to such an area of the medicine bag that it becomes difficult to use the medicine bag when a surface of the area is covered, and the detachable part indicates thereon characteristic information including at least directions on use of the medicine bag.

Abstract: The present invention provides a precursor for producing a tissue regenerating instrument that regenerates a tissue, including: a tube made of a biodegradable material provided with a lumen in a longitudinal direction; a rod made of a biodegradable material swellable with a softening solvent, fixed to an inner wall of the tube substantially parallel to the longitudinal direction of the tube; and an adhesive that fixes the rod to the inner wall of the tube, in which the rod in a non-swelled state has an occupied cross-sectional area perpendicular to the longitudinal direction that is smaller than a cross-sectional area of the lumen of the tube, and the occupied cross-sectional area perpendicular to the longitudinal direction of the rod in a saturated swelled state with the softening solvent is substantially the same as the cross-sectional area of the lumen of the tube.

Abstract: A method of injecting cells into a biological tissue comprising thrusting injection needle (200) under microvibration into tissue (5) secured by suction to tissue suction means (210) and effecting injection of a cell suspension into the tissue through the needle. There is also provided an apparatus for cell injection into the biological tissue.

Abstract: A metal needle is obtained by being dipped in a liquid selected from the group consisting of a strong acid solution of a metal, acetic acid, and butyl acetate, and then dried. Preferably, the strong acid solution of a metal to be used in the dipping treatment may be a nitric acid solution of a metal selected from the group consisting of a transition element, a lanthanoid, and an actinoid, for example, a nitric acid solution of a metal selected from the group consisting of palladium, gadolinium, germanium, beryllium, strontium, scandium, and samarium. The metal needle is a metal needle for insertion into the body that can be reliably imaged even when a general-purpose ultrasound imaging system is used, and thus is useful in confirming insertion of the needle into a blood vessel and arrival of the needle at an organ, and confirming the position of the needle when it is broken.

Abstract: A disposable lancing device including: a housing; a spring member; a lancet having a skin puncture needle, the spring member and the lancet being housed within the housing such that a needle tip of the skin puncture needle is adapted to be projected out from the housing under urging of the lancet by the spring member to perform skin puncture procedure; and a protective cap having a needle passage hole and covering the needle tip of the skin puncture needle, the protective cap being adapted to separate from the skin puncture needle and rotate so that the needle passage hole of the protective cap is positioned on a path of projection of the skin puncture needle, and the skin puncture procedure is performed with the protective cap supported on the housing.

Abstract: A packaged blood purification device including a hollow fiber blood-processing device having a bundle of hollow fibers and a cylindrical container holding the bundle of hollow fibers; and a gas-impermeable container for packaging the hollow fiber blood-processing device. The hollow fiber blood-processing device is sealed together with an oxygen absorber in the gas-impermeable container, and is sterilized with radiation. The blood-processing device is produced by a method including the steps of sealing a hollow fiber blood-processing device in said gas-impermeable container together with an oxygen absorber, and radiation sterilizing the blood-processing device held in the sealed gas-impermeable container.

Abstract: To provide a drug solution preparing kit which can be handled with ease in a substantially aseptic manner, and has no risk that a leakage of a drug solution such as a splash and a dispersion of an aerosol to an ambient environment occurs upon preparation of the drug solution There is provided a drug solution preparing kit including a pre-filled syringe and a transfusing tool, wherein the pre-filled syringe includes a sealing member which seals the tip end and can not be removed from the tip end, and that the transfusing tool includes a one-way valve which can discharge only gas from the system in an irreversible manner, and a filter which is provided so as to adjoin to the second communication channel with respect to the one-way valve.

Abstract: To provide a means capable easily releasing twist of two or more guidewires passed through a guiding catheter without pulling out the guidewires. A twist releasing apparatus has a shaft, a first tube formed at the tip of the shaft and has a first lumen through which two or more guidewires can be passed, a second tube disposed through a gap at the tip side in the axis direction relative to the first tube and has a second lumen through the two or more guidewires can be passed, and a connection portion for connecting the first tube and the second tube so that the two or more guidewires can be passed through the first lumen and the second lumen. The second tube has a slit that is formed in an axis direction and can be elastically deformed. The connection portion can be elastically deformed into a curved shape in the axis direction.

Abstract: There is provided a winged indwelling needle for reducing the possibility of damaging a blood vessel or the like by a cannula, including a movable unit 1 having the cannula and a hub, a tube 2 connected to the rear portion of the hub, a holder 3, and a fixing wing 4, in which the movable unit 1 is provided on the holder 3 so as to be capable of sliding in the axial direction, is capable of changing in position between a position in use and a stored position which is behind the position in use, and the movable unit 1 is fixed to the position in use so as to be releasable. The holder 3 includes a protecting cylinder 26 which stores only the front portion including a blade point 6A of the cannula 6 in the interior thereof when the movable unit is positioned at the stored position and is provided with the fixing wing 4, and a guide member 27 exposed upward for guiding the sliding movement of the movable unit 1.

Abstract: The prefilled syringe filled with a drug in advance, leaking of liquid from the cap is prevented, gas barrier properties are given to the whole of the barrel filled with the drug and the shoulder section so that degradation of the drug is prevented, permeation of microbial contaminants is prevented to a high extent, and efficiency of packing as a compact container can be increased. The prefilled syringe includes a guard-shaped extension projecting from the outer periphery of a shoulder section of the syringe barrel on the nozzle side, and a range from a part where a gasket of the plunger is positioned on the outer surface of the syringe barrel filled with the drug to the guard-shaped extension is covered with barrier packaging.

Abstract: A medical container comprising a body for containing a medicament, the body of the medical container being formed of a multilayered film comprising (i) a layer formed of a linear polyolefin and (ii) a layer formed of a cyclic polyolefin adjacent to the layer (i), and the layer (i) formed of the linear polyolefin satisfying the following conditions (a) and/or (b): Condition (a): an amount of a liquid component, which remains after Soxhlet's extraction with organic solvents followed by evaporation of the solvents, is 0.2% by weight or less, and Condition (b): a branching degree of a component, which remains after Soxhlet's extraction with n-hexane followed by evaporation of n-hexane, is 50 or less per 1,000 carbon atoms.

Abstract: A balloon catheter including a connecting member, a catheter shaft, a balloon and a heat-generating member. The heat-generating member is in contact with a fluid in a distal portion of the catheter shaft. A method for treating a patient including introducing a low temperature fluid which flows through the balloon, introducing energy into a catheter shaft, and converting the energy into heat by a heat-generating member to heat the fluid, whereby an organ of the patient is heated and cooled. In the method, a portion of a diseased tissue of the organ is (i) heated from 35 to 40° C. to 60 to 80° C. within 30 seconds, (ii) expanded by applying a pressure of 500 kPa or smaller to the balloon, and (iii) cooled to 45° C. or lower within 40 seconds.

Abstract: A prefilled syringe composed of a barrel having a luer tip at one end and an open proximal end, the barrel having at least a three layer structure of an innermost layer, an outermost layer, both made of a polyolefin resin, and an intermediate layer made of a resin with a barrier property and sandwiched by the innermost layer and the outermost layer. The barrel is produced through the sequential steps of: (a) injecting a specific amount of a polyolefin resin inside a cavity; (b) injecting a specific amount of a resin excelling in barrier property; (c) injecting a specific amount of the polyolefin resin again; and (d) separating the luer tip surface and an injection unit by pushing off a valve pin provided inside a valve gate or an inner nozzle of the injection unit, which injects the resin excelling in barrier property, toward the direction of the luer tip surface as desired.

Abstract: A drape for clean operation is a flexible bag-shaped structure for maintaining a substantially closed operating space around an operation site. The bag-shaped structure comprises a bottom wall 1 and a transparent top wall 2 and has a closed proximal end 100a and a closed distal end 100b. The bottom wall 1 is provided with at least one operation site-revealing opening 3 close to the proximal end, and the top wall 2 is provided with at least one pair of hand insertion parts 4 at a position close to the operation site-revealing opening 3 to allow the physician to aseptically insert the hands into the operating space, and a closed, openable and closable medical device supply port 5 for supplying medical devices required for operations at a position away from the operation site-revealing opening 3.

Abstract: To provide a syringe in which a covering member whose engagement has been released automatically moves to a projection movement terminal where it can be prevented from returning, and returning of a projection positioned at the projection movement terminal can be limited.