Abstract: A valved needle assembly including a needle hub provided to a proximal end side of a hollow needle, and a valve member incorporated therein for blocking communication with the hollow needle. A protrusion protrudes from a distal end side toward a proximal end side inside the needle hub and the valve member blocks the proximal end side of the protrusion inside the needle hub. A central valve part of the valve member having a slit moves toward the protrusion such that the slit is opened and placed in communication by the protrusion. The central valve part includes a distal end tubular part and a proximal end tubular part extending from its outer circumferential portion toward the distal end side and the proximal end side respectively.

Abstract: A syringe-shaped spraying device includes: a syringe-shaped spraying device main body including a barrel that stores a liquid medicine, a plunger having a front end inserted in the barrel with a gasket being attached to the front end, and a nozzle that is provided with a spraying hole for spraying the liquid medicine and that is connected to a front end of the barrel; a vial adapter having a transfer needle to pierce a vial that stores a liquid medicine so as to suction the liquid medicine; and a connection adapter that is attached to the syringe-shaped spraying device main body and that connects the vial adapter to the syringe-shaped spraying device main body.

Abstract: A triaxial acceleration sensor and a triaxial angular rate sensor are mounted on each of the lower limb portions on both sides of one joint among joints constituting a part of one lower limb of a subject. The acceleration and angular rate of each lower limb portion are measured by the triaxial acceleration sensor and triaxial angular rate sensor while the subject is walking. The orientations of each lower limb portion while walking are calculated on the basis of the measured acceleration and angular rate. A three-dimensional model including the motion trajectory of one joint is constructed by linking the lower limb portions in the calculated orientation to each other. The angle formed by the acceleration vector of one joint when the heel strikes the ground to the movement trajectory in the sagittal plane is calculated as a gait parameter.

Abstract: A dose determination program for an erythropoiesis-stimulating agent that is executable by a computer. The program causes the computer to perform: obtaining a predetermined target hemoglobin concentration; obtaining a first concentration and a first dose in a stable state in which a hemoglobin concentration is stable at the first concentration by repeatedly administering the first dose a plurality of times, and calculating a second dose of the erythropoiesis-stimulating agent based on the obtained target hemoglobin concentration, the obtained first concentration, and the obtained first dose, the second dose of the erythropoiesis-stimulating agent being to be administered by a fixed amount.

Abstract: Provided is a specimen collection tip having a novel structure, with which it is possible to collect a trace amount of a specimen with good quantitative precision. Also provided is a specimen preparation container having a novel structure, with which it is possible to dilute and prepare the specimen collected with the specimen collection tip with good quantitative precision. A specimen collection tip 10, wherein a specimen holding region 12 having a predetermined volume is provided inside the specimen collection tip 10, and in a distal end portion extending from a support part 15, there is formed a specimen collection hole 22 and an air vent hole 24 placing the specimen holding region 12 in communication with a surface 23. Also, a specimen preparation container 26 with a cap 30, wherein the specimen collection tip 10 is attached to the cap 30 at the support part 15.

Abstract: A multilayer culture vessel, comprising a culture vessel part and a reservoir part attached to the culture vessel part, wherein the culture vessel part comprises at least two culture trays that are stacked; the reservoir part comprises a surrounding wall defining an internal space and a port communicating with the internal space; the surrounding wall comprises a first surrounding wall part provided with the port and a second surrounding wall part facing the first surrounding wall part; the culture vessel part has openings communicating individual culture trays of the at least two culture trays with the internal space of the reservoir part; and the openings of the culture vessel part extend toward a first abutting portion that the first surrounding wall part abuts on the culture vessel part from a second abutting portion that the second surrounding wall part abuts on the culture vessel part.

Abstract: The present disclosure provides a method for detecting Alzheimer's cognitive impairment or mild cognitive impairment, comprising: measuring an amount of homocysteic acid in a biological sample from a subject who suffers or possibly suffers from a neurological disease, and detecting Alzheimer's cognitive impairment or mild cognitive impairment based on the measured amount of the homocysteic acid.

Abstract: A stent having a line-shaped body that extends helically in a circumferential direction while reciprocating in an axial direction by continuously alternating straight parts and curved parts, wherein the plurality of straight parts in the line-shaped body have a substantially constant thickness throughout the entire stent, and a certain number of the plurality of curved parts in the line-shaped body have different thicknesses.

Abstract: An artificial joint is characterized by: having a first member including a caput part on which a prescribed curved surface is formed, and a second member including a fossa part having a surface which abuts the prescribed curved surface of the caput part; the second member being rotatable in a flexing direction of a joint with a prescribed point on the caput part being the center of rotation; and the prescribed curved surface of the caput part being defined by a curve which depicts a convex arc toward the side abutting the fossa part when the caput part is viewed from the axial direction of the rotation, and in which, when two arbitrary points are taken on the curve, the radius of curvature of the point positioned further toward the flexing side of the joint on the curve is smaller than the radius of curvature of the other point.

Abstract: A storage case with a biomedical electrode pad for storing a biological signal processing circuit unit for processing an biological electrical signal which has been detected by the biomedical electrode pad, wherein a case body thereof has a storage area for the biological signal processing circuit unit, the storage area being provided in an openable and closable manner, and the biological signal processing circuit unit is detachable with respect to the storage area.

Abstract: Problem to be Solved Provided is a method for manufacturing a pharmaceutical preparation, which safely and simply enables uniformization of contents of a small amount of a drug. [Solution] The method for manufacturing the pharmaceutical preparation includes: using a liquid for dispensing, the liquid containing a drug; and a first application step of applying the drug to a surface of a tablet or a capsule by a dispensing method. In addition, a pharmaceutical preparation according to the present invention includes: a base; and a drug which is applied to a surface of the base by a dispensing method, and the base is a tablet or a capsule.

Abstract: An object is to provide a blood purifying device and an access flow rate measuring method enabling easy and accurate measurement of an access flow rate of an access vessel. A blood purifying device includes a flow rate calculating unit calculating the access flow rate of an access vessel based on an initial blood indicator for blood distributed through a vein side circuit and flowing through the access vessel of a patient, the flow rate distributed through measuring means when a pump is reversed to cause the priming solution to flow out from an artery side circuit, and a blood indicator for the blood diluted with the priming solution which is obtained when the pump is reversed to dilute, with the priming solution, the blood distributed through the vein side circuit.

Abstract: The present invention provides a needle tip protector of a novel structure for an indwelling needle, which enables improvements in safety, etc. as compared with conventional needle tip protectors. A needle tip protector 10 for an indwelling needle includes a tubular peripheral wall 58, and is externally attached over a needle hub 22 of an indwelling needle 16 and moved toward a needle tip 14 side so as to cover the needle tip 14. Detents 74, 74, which are to be detained with the needle hub 22 at a position in a movement of the protector toward the needle tip 14 side of the indwelling needle 16 so as to inhibit backward movement of the protector to the proximal end side of the indwelling needle 16 and to prevent the needle tip 14 from being reexposed, are formed within an inside enclosed by the peripheral wall 58, and are integrally molded with the peripheral wall 58.

Abstract: The present invention relates to a pharmaceutical composition for treating amyotrophic lateral sclerosis. More specifically, the present invention relates to a pharmaceutical composition for treating amyotrophic lateral sclerosis, wherein the pharmaceutical composition comprises mesenchymal stem cells and is intravenously administered.

Abstract: The present invention relates to a pharmaceutical composition containing mesenchymal stem cells administered to a patient subjected to stenting. The present invention relates specifically to: a pharmaceutical composition for repairing and regenerating tissue, comprising mesenchymal stem cells, wherein the pharmaceutical composition is administered to a patient subjected to stenting; and the prevention of in-stent neointimal hyperplasia or in-stent restenosis with the pharmaceutical composition.

Abstract: A puncturing tool for small animals which has a novel structure, facilitates confirmation of the connection state of a capillary tube, and can prevent inadvertent detachment of the capillary tube. A puncturing tool for small animals includes a connecting part for a capillary tube on the proximal end side of a hollow needle, wherein the connecting part has a tapered peripheral wall that expanding and extending in a direction away from the hollow needle, and a tapered peripheral wall has an elastic fitting part, through which the capillary tube is inserted, projecting inward from a middle portion of the tapered peripheral wall in the length direction thereof.