Patents Assigned to Nipro Corporation
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Patent number: 6991635Abstract: An intracardiac suture device comprises: a first shaft assembly 1 including a first shaft 11 and a first suture needle-holding means 4 provided at a distal end of the first shaft 11; a second shaft assembly 2 comprising a second shaft 21; a third shaft assembly 3 comprising a third shaft 31 and a handling portion 33; and a puncture assembly 5 provided at a proximal end thereof with a second suture needle-holding means 51. The second shaft 21 is protrusible by sliding-movement from the distal end of the first shaft 11 toward the first suture needle-holding means 4, and a suture needle 6 is transferable between the first suture needle-holding means 4 and the second suture needle-holding means 51 when the third shaft 31 is slid to the distal end of the second shaft 21 after sliding the second shaft 21 to a position where a suture site is held between the second shaft 21 and the first suture needle-holding means 4.Type: GrantFiled: October 1, 2002Date of Patent: January 31, 2006Assignee: Nipro CorporationInventors: Shinichi Takamoto, Yoshihiro Suematsu, Katsuya Miyagawa, Yoshikazu Kishigami
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Patent number: 6992429Abstract: A lamp for an automobile includes a lamp (10) and a base portion (30) to which the lamp (10) is mounted, in which the lamp (10) includes: a bulb (20); lead wires (11) extending from a base of the bulb (20); and a pinch seal portion (22) formed in the base of the bulb (20) for fixing the lead wires (11), and the base portion (30) includes a resin adapter (40) having a pair of adapter half bodies (40A, 40B) adapted to be placed onto the pinch seal portion (22) from left and right side portions of the pinch seal portion (22) in a transverse direction and mounted on the pinch seal portion (22).Type: GrantFiled: March 24, 2004Date of Patent: January 31, 2006Assignee: Nipro CorporationInventor: Yoshihisa Ishihara
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Patent number: 6979427Abstract: A cost effective apparatus for preparing solutions is provided. The apparatus includes a chamber which is divided by a movable partition into two compartments, a dissolving solution supply line for supplying dissolving solution to a first compartment of the chamber, a solution tank, a solution preparing line connecting the solution tank and the first compartment of the chamber, a solution preparing line connecting the solution tank and a second compartment of the chamber, and a transporting pump provided between the solution tank and the second compartment, and a solution transporting line for transporting the solution prepared in the solution tank and that has been transported to the second compartment to the point of use. The transporting pump may alternatively be provided between the first compartment and the solution tank.Type: GrantFiled: June 14, 2001Date of Patent: December 27, 2005Assignee: Nipro CorporationInventor: Yoshihiko Sano
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Patent number: 6977231Abstract: A suturable adhesion-preventing membrane has high suture strength, good biocompatibility, decomposition and absorption in a living body, sufficient adhesion-preventing effect, and desirable guided tissue regeneration. The membrane is composed of at least one non-woven fabric layer made of collagen fibers, or a laminated membranous substance consisting of at least one non-woven fabric layer made of collagen fibers and at least one sponge layer made of collagen, and a coating layer of gelatin or hyaluronic acid on the surface or surfaces of the above membrane. Preferably, the membrane comprises one to six compressed cross-linked collagen non-woven fabric layers wherein a layer has a fibers having a fiber diameter of 0.05 mm to 1.0 mm, a bulk density of 5.0×10?4 to 5 g/cm3 and a thickness of 0.1 mm to 50 mm, and a coating layer containing gelatin or hyaluronic acid and having a thickness of 0.05 mm to 20 mm, wherein the coating layer covers one or both sides or a part or whole of the surface of the membrane.Type: GrantFiled: January 21, 2000Date of Patent: December 20, 2005Assignee: Nipro CorporationInventor: Kazuhisa Matsuda
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Patent number: 6953482Abstract: This invention relates to an instrument for regenerating a living organism tissue or organ, characterized in that a support (A) formed from a biodegradable material or a bioabsorbable material includes a sponge-like fine matrix (B) formed from a biodegradable material or a bioabsorbable material and a linear guide channel (C) for a living organism tissue or organ.Type: GrantFiled: April 26, 2002Date of Patent: October 11, 2005Assignees: Nipro CorporationInventors: Nobutoshi Doi, Kazuhisa Matsuda, Ken-ichiro Hata, Kensuke Sakai
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Publication number: 20050222026Abstract: The present invention provides a nitrosylated albumin variant wherein one or more amino acid residues of constituent amino acid sequences are substituted, or a different amino acid residue is inserted into a part of the constituent amino acid sequences. The albumin variant has sufficient antimicrobial property and permits application as various useful pharmaceutical compositions.Type: ApplicationFiled: October 29, 2004Publication date: October 6, 2005Applicant: NIPRO CORPORATIONInventors: Masaki Otagiri, Takaaki Akaike
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Patent number: 6929598Abstract: A catheter for artificial insemination which is a hollow cylindrical catheter having open ends at both ends, the catheter comprising a small diameter portion forming a distal end portion, a large diameter portion forming a proximal end portion and a tapered portion connecting the small diameter portion and the large diameter portion, a total inner volume of the catheter being from 0.2 to 1.0 ml.Type: GrantFiled: May 8, 2003Date of Patent: August 16, 2005Assignee: Nipro CorporationInventors: Satoru Kaneko, Nobuo Takagi
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Patent number: 6929620Abstract: An injector for liquid medicine comprises a cylindrical body 1, first and second gasket 2, 3 contained in a lumen of cylindrical body 1. The cylindrical body 1 is provided with a fluid inlet 13 and a fluid outlet 14 in opposite sides of the cylindrical body 1 with respect to the longitudinal axis thereof. Second gasket 3 is spaced from the first gasket 2 to form a fluid chamber 4 between them. The first gasket 2 is adapted to be moved by sliding along the inner wall of the cylindrical body 1 from a first position to the distal end 11 of cylindrical body 1 via a second position. The fluid inlet 13 is opened at a position closer to the distal end 11 of the cylindrical body 1 than the outlet 14 is. The first gasket 2 is stopped at a second position where the fluid chamber 4 is communicated with the fluid outlet 14 but prevented from fluid-communication with the fluid inlet 13.Type: GrantFiled: March 15, 2002Date of Patent: August 16, 2005Assignee: Nipro CorporationInventor: Mitsuru Hasegawa
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Patent number: 6923793Abstract: A clamp for a winged needle that functions simultaneously as a protector and as a clamp and that does not require a recapping operation is provided. The clamp includes a flexible curved portion 1 including a tube insertion hole 11 provided on the proximal side and an upper member 2 and a lower member 3 connected via the curved portion 1 and which can be engaged on the distal sides thereof. The clamp is adapted to pressurize the tube 44 when the upper member 2 and the lower member 3 are engaged, and to generate a clearance through which at least a wing 4 can be introduced when the upper member 2 and the lower member 3 are not engaged. The upper member 2 or the lower member 3 is provided with a space 32 in which the needle 41 and the hub 42 can be stored.Type: GrantFiled: June 1, 2001Date of Patent: August 2, 2005Assignee: Nipro CorporationInventors: Masashi Ishida, Hiroyuki Nakagami
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Patent number: 6923987Abstract: A solid preparation for dialysis for preparing a double preparation type sodium bicarbonate solid preparation for dialysis in which there is no fear that a sugar component is decomposed or colored, and which can maintain stability and is also excellent in content homogeneity and a process for producing the same. The solid preparation for dialysis is a mixture of a first composition composed of core particles including sodium chloride and a coating layer containing one or more electrolytes, a second composition composed of core particles including a sugar that is covered with a coating layer comprising the same sugar or a different sugar, and an acid.Type: GrantFiled: September 27, 2001Date of Patent: August 2, 2005Assignee: Nipro CorporationInventors: Toshiya Kai, Kazuyuki Yamamoto, Kazutaka Fujiki, Makoto Sato
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Patent number: 6916655Abstract: A cultured skin and a grafting cultured skin sheet are provided, each of which is a cultured reconstructive skin with a high take rate using cells collectable from cells originated from tissue included in an umbilical cord such as tissue included in an umbilical cord originated from a human fetus. The grafting cultured skin stratified sheet is prepared by placing an epithelium sheet on the top surface of a cultured dermis. The cultured dermis includes as components a cultured skin containing cells originated from a tissue included in an umbilical cord, such as umbilical cells, more concretely, umbilical fibroblast cells, being separated and cultured, preferably in a collagen nonwoven fabric. On the other hand, the epithelium sheet is prepared by culturing and stratifying the umbilical cord epithelium cells.Type: GrantFiled: November 21, 2002Date of Patent: July 12, 2005Assignee: Nipro CorporationInventors: Shigeru Yasumoto, Masakatsu Takeuchi
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Patent number: 6913591Abstract: Personal injector for liquid medicine comprises a housing provided with needle-mounting part, medicine container holder and connecting port to a personal computer; plunger arranged in housing; electric motor for driving plunger; limit switch for limiting the forward movement of plunger; starting point sensor for detecting return of plunger to the starting point; and substrate having display and mode-select switch mounted thereon. The plunger is movable between the starting point and forward limit point. Limit switch is arranged at the forward limit point. When limit switch is turned on, motor drives plunger in reverse to move it to the starting point thereof.Type: GrantFiled: March 13, 2002Date of Patent: July 5, 2005Assignee: Nipro CorporationInventors: Takehito Itoh, Susumu Kobayashi, Hideyuki Tomita
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Patent number: 6901975Abstract: The drug solution container with a connector for communicating contains a drug solution container having at a tip end thereof an injection needle connecting part, and a hollow connector for communicating attached to a tip end of the drug solution container, and the connector for communicating contains a cylindrical guide part with a bottom capable of being slidably attached to an opening of a vial, and a hollow penetrating member provided at a center of the bottom of the guide part to penetrate the bottom. The penetrating member contains a penetrating needle at a tip end side with respect to the bottom, and a connecting part at a base end side with respect to the bottom, and the connecting part is connected to the injection needle connecting part through a fragile portion. According to the drug solution container with a connector for communicating, an operation for preparation of a drug solution can be easily carried out in a short period of time without causing injury of an operator or coring.Type: GrantFiled: June 30, 2003Date of Patent: June 7, 2005Assignee: Nipro CorporationInventors: Masafumi Aramata, Hideki Yagi, Toshikazu Hirayama, Satoru Igarashi, Yoshihisa Murai, Teruhisa Hirobe
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Publication number: 20050085410Abstract: The present invention provides a method of producing a complex of albumin and a deoxy form metal complex having a porphyrin structure, which includes mixing albumin and a metal complex having a porphyrin structure under a gas atmosphere substantially free of carbon monoxide and oxygen, as a method of producing an artificial oxygen carrier containing a complex of albumin and a metal complex having a porphyrin structure, under a deoxidation (nitrogen, other inert gases) atmosphere without using carbon monoxide.Type: ApplicationFiled: August 27, 2004Publication date: April 21, 2005Applicant: NIPRO CORPORATIONInventors: Eishun Tsuchida, Shinji Takeoka, Teruyuki Komatsu, Toshiya Kai, Naohisa Katayama, Ippei Fukutomi, Makoto Sato
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Patent number: 6867193Abstract: An albumin preparation that prevents onset of hepatic encephalopathy caused by conventional amino acid preparations and enhances an effect of improving the symptoms is provided. The albumin preparation containing amino acids is characterized in that a content of albumin is 0.01 to 1.0 w/v %, a content of plurality of amino acids containing branched amino acid is 5 to 10 w/v %, a content of the branched amino acids is equal to or more than 30 w/w % on the basis of the content of total amino acids and further, the Fischer ratio (branched amino acid/[phenylalanine+tyrosine] (molar ratio)) is equal to or more than 20.Type: GrantFiled: January 14, 2000Date of Patent: March 15, 2005Assignee: Nipro CorporationInventors: Yukio Nakamura, Yasuhiro Tsutsui, Makoto Sato
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Patent number: 6855127Abstract: A needle assembly comprising a needle, a needle hub in which the needle is secured at a distal end portion of the needle hub, a protector having an elongated rod-shaped main body and a needle tip protection part provided on the distal end of the main body for sliding on the needle, and a cylindrical hub cover having an inner channel provided on the distal end of the needle hub. The needle hub and the hub cover each have such a shape as to form a side hole when the needle hub and the hub cover are integrally joined, and the protector main body moves to the distal end or the proximal end while inserted in the side hole.Type: GrantFiled: January 24, 2002Date of Patent: February 15, 2005Assignee: Nipro CorporationInventors: Hiroyuki Nakagami, Satoshi Kamimura
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Patent number: 6846299Abstract: Method for a continuous recirculating peritoneal dialysis wherein the peritoneal dialysis fluid is infused into a peritoneal cavity of a patient and then, typically on a continuous process basis a portion of the dialysis fluid is sequentially drained from the cavity, cleansed through an extracorpreal dialyzer, and reinfused into the cavity. The dialysis fluid contains as an osmotic agent a substance which does not substantially permeate through pores of hollow fiber membrane of an extracorporeal dialyzer, preferably an osmotic agent having a molecular weight of about 20,000 to about 100,000. The supplemented amount of the osmotic agent is reduced or not needed during the dialysis.Type: GrantFiled: June 17, 2002Date of Patent: January 25, 2005Assignee: Nipro CorporationInventors: Toshiaki Masuda, Hidetoshi Yamamoto
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Patent number: 6815025Abstract: An easily peelable film comprising a mixture of a propylene/&agr;-olefin copolymer (A), a propylene/&agr;-olefin copolymer (B) having an &agr;-olefin content different from that of the copolymer (A), and/or a propylene homopolymer (C). The easily peelable film has excellent heat resistance, flexibility, and transparency and further a broad temperature range for low temperature welding at which peelable partition walls can be formed.Type: GrantFiled: February 23, 2004Date of Patent: November 9, 2004Assignee: Nipro CorporationInventors: Shin-ichi Kawamura, Hiroshi Fukushima
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Patent number: 6812173Abstract: Lighting glass containing 0.3 to 1.0% by weight of Sb as Sb2O3 and 0.5 to 1.0% by weight of S as SO3 in a SiO2—Al2O3—R1O—R22O-based glass (where R1 represents Ca, Sr, Mg and Ba and R2 represents Na, K and Li) in which colloids comprising SbS2 and/or Sb2S3 are generated in the glass.Type: GrantFiled: November 27, 2002Date of Patent: November 2, 2004Assignee: Nipro CorporationInventor: Yoshihisa Ishihara
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Patent number: D506256Type: GrantFiled: May 23, 2003Date of Patent: June 14, 2005Assignees: Nipro Corporation, Schering AktiengesellschaftInventors: Jun Miyoshi, Masafumi Aramata, Makoto Iwaike, Hidetoshi Tanaka