Patents Assigned to Nipro Corporation
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Patent number: 6800248Abstract: A method for cleaning a hemodialysis system after completion of dialysis, characterized in that ozone water produced by an apparatus for producing high concentration ozone water 5 and having an average ozone concentration of not less than 15 ppm is sequentially guided to dialysate pipes of a hemodialysis system 4 after completion of dialysis including a water supply tube for dialyzing water 40, a water supply tube for dialysate 41 and a water drainage tube for dialysate 42; and ozone water having an average ozone concentration of not less than 2 ppm is drained from the water drainage tube 42. It is possible to prevent carbonates, proteins, biofilms and the like from adhering so that cleaning with excellent sterilizing property can be realized.Type: GrantFiled: March 21, 2001Date of Patent: October 5, 2004Assignee: Nipro CorporationInventors: Toshiaki Masuda, Yukari Masuda
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Publication number: 20040188281Abstract: A medicine bag, which includes a bag body having a medicine storage chamber that stores a medicine in such a way that the medicine is visually confirmed through a light-transmission portion provided in at least one part of the bag body, the bag body having a weak seal portion that divides the medicine storage chamber into a plurality of division spaces, and the sealing of the weak seal portion adjacent to a specific division space being removed by increasing the internal pressure of that division space, including: a cover sheet which is peelably attached to the bag body; and a requisitely-used portion which is used in the process shortly before the medicine is administered, in which the cover sheet includes: a light-shielding portion which shields from the light the medicine stored in at least one division space by covering a predetermined part of the light-transmission portion; and a continuously-formed portion which is continuously formed in the light-shielding portion and is placed so that the requisitely-Type: ApplicationFiled: March 15, 2004Publication date: September 30, 2004Applicant: NIPRO CORPORATIONInventors: Masanobu Iwasa, Minoru Honda, Masaki Ikenoue, Kenji Omori
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Publication number: 20040180837Abstract: A porphyrin compound represented by general formula (A): 1Type: ApplicationFiled: March 12, 2004Publication date: September 16, 2004Applicant: NIPRO CORPORATIONInventors: Eishun Tsuchida, Teruyuki Komatsu, Akito Nakagawa, Naomi Ohmichi
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Patent number: 6786891Abstract: An indwelling needle of the present invention comprises a flexible cover needle, a fixing wing externally fitted and fixed on a distal end of the cover needle, a cover needle hub mounted on a proximal end of the cover needle, an inner needle which is removably inserted through the cover needle and the cover needle hub and the distal end of which projects forwards from the cover needle, and a protecting tube for preventing kink of the cover needle which is externally fitted between the fixing wing and the cover needle hub on the cover needle.Type: GrantFiled: May 21, 2003Date of Patent: September 7, 2004Assignee: Nipro CorporationInventor: Katsuhiro Hiejima
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Patent number: 6777052Abstract: The present invention provides a plastic container containing albumin solution and a packaged plastic container containing an albumin solution. The plastic container containing an albumin solution having an albumin concentration of 1 to 500 mg/ml, has at least one inlet/outlet for a liquid, and has a water vapor permeability of 1.5 g/m2/day·1013.25 hPa or less when the vapor permeability is measured at a pressure of 1013.25 hPa per surface area of 1 m2 for 24 hours at a temperature of 25° C. and at a relative humidity of 60%. The plastic container containing an albumin solution can be packaged with an outer packaging material to provide the packaged plastic container.Type: GrantFiled: March 27, 2002Date of Patent: August 17, 2004Assignee: Nipro CorporationInventors: Toshiya Kai, Hideaki Murata, Makoto Sato
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Patent number: 6773427Abstract: An infusion container comprising a communication port capable of being connected with a syringe, a container main body, a communication channel for providing communication between the inside of the container main body and the inner lumen of the communication port, and a sterilization filter provided in the communication channel, wherein the communication port is closed with a rubber stopper provided with a slit allowing the top end tip of the syringe to pass therethrough and the communication channel is closed with a closing means capable of being easily opened.Type: GrantFiled: January 31, 2002Date of Patent: August 10, 2004Assignee: Nipro CorporationInventor: Nobuo Takagi
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Patent number: 6749818Abstract: A cost effective solution preparing apparatus includes a chamber which is divided into two compartments by a movable partition; a dissolving solution supply line for supplying a dissolving solution to the first compartment of the chamber; a solution tank connected with the first compartment and the second compartment through a first solution preparing line and through a second solution preparing line, respectively; a transporting pump provided in the second solution preparing line; a concentration meter; a solution transporting line for transporting the solution prepared and filled in the second compartment to a point of use; and a circulating line, in which the solution tank is exemplified as a U-shape tank constructed of a relatively small-diameter upstream tank portion and a relatively large-diameter downstream tank portion, and at least one filter is provided in a downstream portion of the downstream tank portion.Type: GrantFiled: July 26, 2001Date of Patent: June 15, 2004Assignee: Nipro CorporationInventors: Yoshihiko Sano, Hidetoshi Saio
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Patent number: 6733676Abstract: A dialyzing system comprises a dialyzer 10 and an ultrafiltration-regulating unit 24 for regulating inflow and out flow of a dialysate to or from the dialyzer 10 to regulate ultrafiltration. The dialyzing system is adapted to determine a blood pressure from a dialysate pressure detected by a pressure transducer 28 at the time of temporary suspension of the ultrafiltration without use of a special line for measurement of pressure in the blood flow line and free from danger of blood leakage from the blood flow line.Type: GrantFiled: February 19, 2002Date of Patent: May 11, 2004Assignees: Nipro Corporation, Nikkiso Co., Ltd., Nextier Co., Ltd.Inventor: Ichiro Takai
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Patent number: 6720045Abstract: An easily peelable film comprising a mixture of a propylene/&agr;-olefin copolymer (A), a propylene/&agr;-olefin copolymer (B) having an &agr;-olefin content different from that of the copolymer (A), and/or a propylene homopolymer (C) and a medical packaging container produced using the same. The easily peelable film has excellent heat resistance, flexibility, and transparency and further a broad temperature range for low temperature welding at which peelable partition walls can be formed.Type: GrantFiled: December 8, 2000Date of Patent: April 13, 2004Assignee: Nipro CorporationInventors: Shin-ichi Kawamura, Hiroshi Fukushima
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Patent number: 6676638Abstract: An indwelling needle includes: a container barrel having a retraction mechanism (an actuator and urging element etc.,) for retracting the inner needle after use; and an outer needle support lid element for prohibiting the outer needle from being withdrawn into the container barrel. The outer needle support lid element has a gutter-like portion, which is a short cylinder formed in part with a cutout portion with its inside dimension designed so as to allow the inner needle to pass therethrough and be smaller than the outside dimension of the needle base (more exactly, the outer dimension of the flange of the needle base) of the outer needle.Type: GrantFiled: February 8, 2001Date of Patent: January 13, 2004Assignees: Mitsubishi Pencil Kabushiki Kaisha, Nipro CorporationInventors: Hiroshi Takagi, Kentaro Takemae, Kunihiko Tanaka
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Patent number: 6669762Abstract: An air trap comprises an air reservoir to be arranged in a liquid circulation line, and a hydrophilic filter which permits a liquid to permeate but does not permit gas bubbles to permeate, and which is arranged in the air reservoir to separate an upstream side of the liquid circulation line from the downstream side of the liquid circulation line. The filter has pores which meet conditions defined by equation: P<4h/d, where P represents a gas pressure, d is a diameter of the pores of the filter, and h is a surface tension of the liquid.Type: GrantFiled: December 21, 2001Date of Patent: December 30, 2003Assignee: Nipro CorporationInventors: Toshikazu Hirayama, Daisuke Ueno
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Patent number: 6656355Abstract: A cost effective apparatus for preparing dialysate solution which can finely adjust the concentration of dialysate solution is described. The apparatus comprises a chamber 2, the inside of which is divided into three compartments 21, 22, 23 by a movable partitions 24, 25, a dissolving solution supply line 1 for supplying dissolving solution to the first compartment 21, a solution tank 5, a dialysate solution preparing line 31 connecting the solution tank 5 and the first compartment 21, a dialysate solution preparing line 32 connecting the solution tank 5 and the third compartment 23, a transporting pump 4 provided in the dialysate solution preparing line 32, a powder supply means 7 provided above the solution tank 5, and a dialysate solution transporting line 6 for transporting the dialysate solution prepared and filled in the third compartment 23 to the point of use, a by-pass line 81, and a circulating line 91.Type: GrantFiled: July 13, 2001Date of Patent: December 2, 2003Assignee: Nipro CorporationInventor: Yoshihiko Sano
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Patent number: 6656167Abstract: A piercing needle having a low piercing resistance even if repeatedly caused to pierce is provided. The piercing needle has an undercoat of a silane coupling agent, preferably, an amino group-containing alkoxysilane or an epoxy group-containing alkoxysilane, and an outer surface of a mixture of a (1) reactive silicone such as a reaction product of an amino group-containing alkoxysilane, an epoxy group-containing alkoxysilane and a silicone having silanol groups at both terminal ends, with (2) a non-reactive silicone.Type: GrantFiled: January 8, 2001Date of Patent: December 2, 2003Assignee: Nipro CorporationInventors: Taku Numao, Masashi Ishida, Nobuo Wada, Takeshi Nizuka
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Patent number: 6649057Abstract: A dialysate preparing apparatus in which concentration of dialysate can be finely adjusted is provided. The dialysate preparing apparatus comprises a chamber 2, the inside of which is divided into four compartments 21, 22, 23, 24 by movable partitions 25, 26, 27; a dissolving solution supply line 1 for supplying dissolving solution to the first compartment 21; a solution tank 5; dialysate preparing lines 31, 32 connecting the solution tank 5 with the first compartment 21 and with the second compartment 22, respectively; a transporting pump 4 provided in the dialysate preparing line 32; a concentration meter N; a powder supply means 7; and dialysate lines 61, 62 connecting the second compartment 22 and the fourth compartment 24 with a dialyzer D, respectively; a circulating line 81; and a waste liquid discharge line 9.Type: GrantFiled: July 13, 2001Date of Patent: November 18, 2003Assignee: Nipro CorporationInventor: Yoshihiko Sano
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Patent number: 6638254Abstract: An indwelling needle assembly having an outer needle to be pieced and retained in tissue of a living body, an outer needle hub to which the outer needle is fixed, an inner needle slidably inserted in a lumen of the outer needle and having a sharp blade edge, an inner needle hub to which the inner needle is fixed, and a needle guard having a multi-tube structure composed of a plurality of telescoping tubes and capable of accommodating the inner needle and the inner needle hub therein. The assembly has a first elastic means provided in the needle guard for withdrawing the tubes, a second elastic means that engages with the inner needle hub and biases the hub toward the proximal end of the guard, and a stopper means that holds the inner needle hub and the needle guard against biasing forces of the elastic means.Type: GrantFiled: October 22, 2001Date of Patent: October 28, 2003Assignee: Nipro CorporationInventor: Hiroyuki Nakagami
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Patent number: 6616631Abstract: A holder sleeve (1) incorporates an urging means (8) for urging an inner needle (12) to the proximal end side and an actuator (6) which engages the inner needle (12) at the near distal end portion of the holder sleeve (1) so that the inner needle (12) can be released and the tip of the inner needle is projected from the holder sleeve (1). This actuator (6) has an inner needle hub (12a) fixed at the front end thereof and is formed with an actuating member (6a) projected outside the holder sleeve (1). The holder sleeve (1) has a slit (2) which extends to the proximal end side so as to allow the actuating member (6a) of the actuator (6) to slide and assures the path of movement of the actuator (6) released from the near distal end portion of the holder sleeve (1). The inner needle (12) is adapted to be released from the holder sleeve (1) when the actuating member (6a) is moved away from the holder sleeve (1) within the same plane that includes the axis of the holder sleeve (1).Type: GrantFiled: March 29, 2002Date of Patent: September 9, 2003Assignees: Mitsubishi Pencil Kabushiki Kaisha, Nipro CorporationInventors: Hiroshi Takagi, Kentaro Takemae
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Patent number: 6586247Abstract: A medium for cultivating an animal embryo that is capable of readily culturing a fertilized ovum can be provided. A cultivation medium is separated into two parts, i.e., one is a neutral aqueous solution and the other is an acidic aqueous solution. The two parts are mixed before use. The neutral aqueous solution contains a nutrient such as lactic acid or a lactic salt and another inorganic component and an indicator that indicates a state of a development environment with its color, and the acidic aqueous solution contains a nutrient such as pyruvic acid and an antibiotic. The pH change in the medium according to cultivation of animal embryo can be determined by the change of the color of the indicator.Type: GrantFiled: January 5, 2000Date of Patent: July 1, 2003Assignee: Nipro CorporationInventor: Satoru Kaneko
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Patent number: 6582604Abstract: A dialysis system which does not need to use a physiological saline in replenishing a solution or cleaning and priming the dialysis system, does not need a troublesome setting operation and can easily and accurately set a flow rate of a replenisher solution. The dialysis system includes a closed-type water-removal control apparatus 1, a dialyzer 2, a fresh dialysate line 3 as well as a used dialysate line 4, an RO water pressurizing line 5, an RO water pressurizing pump 51 provided in the RO water pressurizing line 5, an artery side blood line 6, a blood pump 61 provided at the artery side blood line 6 and a vein side blood line 7. According to the dialysis system, by pressurizing RO water into a communication line of the used dialysate, dialysate is made to flow from a dialysate flow path 21 into a blood flow path 22 through a dialysis membrane 23 of the dialyzer 2 and the inside of a blood circulation path can be cleaned and primed.Type: GrantFiled: June 25, 2001Date of Patent: June 24, 2003Assignee: Nipro CorporationInventors: Taku Nikaido, Mistutaka Ueda
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Patent number: 6576310Abstract: A medical tubing having rigidity, flexibility, transparency and heat resistance and, additionally, acceptable flexural modulus and tensile strength and further having no stickiness between surfaces of the tubing is provided. The medical tubing is composed of a resin composition containing a low-density ethylene/&agr;-olefin copolymer having a density of 0.860-0.900 g/cm3 polymerized with a metallocene catalyst and a styrene/ethylene-butylene/olefin block copolymer.Type: GrantFiled: January 8, 2001Date of Patent: June 10, 2003Assignee: Nipro CorporationInventor: Mamoru Shimada
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Patent number: D475461Type: GrantFiled: August 15, 2002Date of Patent: June 3, 2003Assignee: Nipro CorporationInventors: Nobuo Takagi, Naohiro Atsumi, Taku Numao