Patents Assigned to Nipro Corporation
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Publication number: 20080009061Abstract: An object of the present invention is to provide a method for preserving pancreatic islet, a container for preserving pancreatic islet and a kit for transplanting pancreatic islet in order to effectively preserve the pancreatic islet. The present invention presents; a method for preserving a liquid including pancreatic islet in a container for preserving pancreatic islet, wherein at least a part of the container wall face consists of a film having an oxygen permeation coefficient of 2500 cm3/m2·day·atm or greater; a method for preserving a liquid including pancreatic islet in a container for preserving pancreatic islet, wherein at least a part of the container wall face consists of a film having a carbon dioxide permeation coefficient of 1000 to 20000 cm3/m2·day·atm; and a container for preserving pancreatic islet for use in the above-described method, and a kit for transplanting pancreatic islet comprising the container for preserving pancreatic islet.Type: ApplicationFiled: July 3, 2007Publication date: January 10, 2008Applicants: NIPRO CORPORATION, TOHOKU UNIVERSITYInventors: Masafumi Goto, Yoshihiro Yoshikawa, Kei Matsuo
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Patent number: 7314476Abstract: A balloon catheter for interatrial septum dehiscence including an expandable and contractible balloon, and a shaft to which the balloon can be attached at the distal end thereof, wherein fixing members are provided at balloon mounting portions to be attached to the shaft. The fixing members are a pair of members in opposed relationship to each other at the ends of the balloon. The pair of members generally has an identical shape.Type: GrantFiled: January 21, 2005Date of Patent: January 1, 2008Assignee: Nipro CorporationInventors: Hideaki Senzaki, Toshiki Kobayashi, Katsuya Miyagawa, Hideaki Kataoka
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Patent number: 7294122Abstract: A transfer needle comprises: a liquid-specific member; and a medicament-specific member to be separably connected or joined to the liquid-specific member in a liquid-tight state. The liquid-specific member comprises: a liquid-specific hollow needle projecting toward the opposite side from the medicament-specific member. The medicament-specific member comprises: a medicament-specific hollow needle projecting toward the opposite side from the liquid-specific member and communicating with the liquid-specific hollow needle. A female luer is provided on at least one of the liquid-specific member and the medicament-specific member at a position opposing to the other. The female luer communicates with the one hollow needle and is separably connected with an injection needle connecting portion of a syringe in a liquid-tight state.Type: GrantFiled: July 16, 2004Date of Patent: November 13, 2007Assignee: NIPRO CorporationInventors: Tomohiko Kubo, Shuji Hasegawa, Yoshiyuki Sunaga, Takao Kinoshita
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Patent number: 7293646Abstract: A plural-chamber container capable of indicating whether or not a peelable partition wall is peeled and hence a medical professional can quickly become aware of a state of communication among respective chambers when using the plural-chamber container, wherein the plural-chamber container formed of a synthetic resin film and a plurality of chambers compartmentalized by a peelable partition wall formed by thermally welding part of the opposed films, characterized in that a means capable of indicating the peeling of the partition wall is provided on a surface of the plural-channel container.Type: GrantFiled: October 30, 2003Date of Patent: November 13, 2007Assignee: Nipro CorporationInventors: Toshiaki Masuda, Hiroshi Fukushima, Hiroshi Todo
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Patent number: 7285379Abstract: The present invention provides a method of producing a complex of albumin and a deoxy form metal complex having a porphyrin structure, which includes mixing albumin and a metal complex having a porphyrin structure under a gas atmosphere substantially free of carbon monoxide and oxygen, as a method of producing an artificial oxygen carrier containing a complex of albumin and a metal complex having a porphyrin structure, under a deoxidation (nitrogen, other inert gases) atmosphere without using carbon monoxide.Type: GrantFiled: August 27, 2004Date of Patent: October 23, 2007Assignee: Nipro CorporationInventors: Eishun Tsuchida, Shinji Takeoka, Teruyuki Komatsu, Toshiya Kai, Naohisa Katayama, Ippei Fukutomi, Makoto Sato
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Patent number: 7282041Abstract: A multi lumen catheter including an inner tube having a front tip, an outer tube, a tube or lumen for inserting a guide wire, a blood extraction lumen and a blood return lumen which are formed in the outer tube and inner tube, respectively, or both in the outer tube, wherein the inner tube is inserted in the outer tube, and allowed to slide relative thereto, and the front tip is jointed to the front end of the outer tube to shut off communication of the lumens with the exterior. A multi-lumen catheter with balloon includes a balloon provided on a tabular body at a front end thereof, a blood return port and a blood extraction port provided in the tubular body on opposite sides of the balloon, and an outer cylinder slidable on the tubular body to close the blood extraction and blood return ports and the balloon.Type: GrantFiled: June 26, 2003Date of Patent: October 16, 2007Assignee: Nipro CorporationInventors: Junichi Igarashi, Katsuhiro Hiejima
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Patent number: 7276052Abstract: A medical aspirator including an aspiration port, a reciprocating type electric pump for performing vacuum aspiration, a ventilation path which connects the aspiration port and the electric pump, an exhaust port, and an atmospheric pressure obtaining release valve for releasing a negative pressure in the ventilation path to obtain atmospheric pressure therein. The medical aspirator is particularly useful for percutaneous thrombus removal operation. A diaphragm pump is used as the electric pump. An electromagnetic valve is used as the atmospheric pressure obtaining release valve. The atmospheric pressure obtaining release valve is opened and closed in association with stopping and starting of the electric pump. A cell is provided as an internal power supply.Type: GrantFiled: January 15, 2004Date of Patent: October 2, 2007Assignee: Nipro CorporationInventors: Susumu Kobayashi, Tomoyuki Tejima
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Patent number: 7267653Abstract: A blood collection needle which includes a needle for puncturing a patient's skin; a needle for puncturing a rubber plug which seals a blood collection tube; a hub for securing respective proximal portions of the two needles; a resilient cap fitted to the hub; and a valve member disposed in the internal passage of the hub which allows only blood flow from the needle used to puncture a patient's skin to the needle used to puncture the rubber plug which seals the blood collection tube. The valve member includes a bowl portion disposed so that the opening is faced toward the needle for puncturing the rubber plug and a guiding portion provided on a bottom surface of the bowl portion for causing the valve member to move to a predetermined position which closes the internal passage.Type: GrantFiled: July 7, 2005Date of Patent: September 11, 2007Assignee: Nipro CorporationInventors: Yoshio Higaki, Yoshikuni Uchida
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Patent number: 7253259Abstract: A protein produced by gene recombinant technology, including at least one domain selected from domains I, II, and III of serum albumin but having a different structure from that of native albumin; and a method of producing the protein. The protein has an enhanced functional activity or activities selected from among various functional activities or serum albumin including antibacterial activity, antioxidative effect, inflammation inhibitory effect, in vivo substance transporting action, and enzymatic activity.Type: GrantFiled: January 28, 2005Date of Patent: August 7, 2007Assignee: Nipro CorporationInventors: Masaki Otagiri, Yoshinori Kida, Naohisa Katayama, Toshiya Kai
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Patent number: 7250042Abstract: A thrombus suction catheter which is a tube having a distal end opening formed by an angled cut surface. In the distal end opening, at least a part on the proximal end side of the cut surface is formed in a concave shape in an angled direction, and the distal end side of the cut surface is formed to be flat and flexible. With the distal end configuration, suction and crossing are significantly improved.Type: GrantFiled: January 22, 2004Date of Patent: July 31, 2007Assignee: Nipro CorporationInventors: Yuichi Kataishi, Satoru Mori, Yoshihiko Sano, Toshihiro Kikuchi, Takaaki Isshiki
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Publication number: 20070173778Abstract: During use of a drug solution injector for continuous injection of a drug solution such as an anesthetic, an analgesic agent, an anticancer agent, an antibiotic, etc., into the body, it would be possible to determine an accurate injection volume of the drug solution by weighing the drug solution reservoir with a weighing scale such as an electronic balance. However, the above procedure is difficult to carry out at home and is inconvenient for hospitals since it requires use of the weighing scale at each measurement. It is an object of the present invention to provide a drug solution injector with a weighing scale that provides a solution for the above problems, is compact, does not disturb handling and enables to determine an accurate injection volume of the drug solution.Type: ApplicationFiled: February 8, 2005Publication date: July 26, 2007Applicant: NIPRO CORPORATIONInventors: Yasuhiko Morita, Atsushi Funayama, Satoki Hino
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Patent number: 7243787Abstract: A medicine bag, which includes a bag body having a medicine storage chamber that stores a medicine in such a way that the medicine is visually confirmed through a light-transmission portion provided in at least one part of the bag body, the bag body having a weak seal portion that divides the medicine storage chamber into a plurality of division spaces, and the sealing of the weak seal portion adjacent to a specific division space being removed by increasing the internal pressure of that division space, including: a cover sheet which is peelably attached to the bag body; and a requisitely-used portion which is used in the process shortly before the medicine is administered, in which the cover sheet includes: a light-shielding portion which shields from the light the medicine stored in at least one division space by covering a predetermined part of the light-transmission portion; and a continuously-formed portion which is continuously formed in the light-shielding portion and is placed so that the requisitely-Type: GrantFiled: March 15, 2004Date of Patent: July 17, 2007Assignee: Nipro CorporationInventors: Masanobu Iwasa, Minoru Honda, Masaki Ikenoue, Kenji Omori
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Patent number: 7238169Abstract: A safety indwelling needle including an inner needle unit 1 having an inner needle 8, an inner needle hub 14 and a housing member 13 disposed at a distal side of the inner needle hub 14, and an outer needle unit 2 having an outer needle 4, an outer needle hub 5 and an outer needle cap 9, characterized in that the housing member 13 includes openings for allowing penetration of the inner needle 8 at a distal end and a proximal end thereof, an internal space for storing only a distal end portion of the inner needle 8 including a needlepoint 3 thereof when the inner needle 8 is drawn out from the outer needle 4, and a shielding member which automatically closes the opening at the proximal end of the housing member 13 by a magnetic force.Type: GrantFiled: February 25, 2005Date of Patent: July 3, 2007Assignee: Nipro CorporationInventors: Nobuo Takagi, Masahisa Tanimoto, Yuki Hiraoka
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Patent number: 7225949Abstract: A liquid drug container comprises a container body 1; a nozzle member 2 liquid-tightly mounted on the container body 1; and a nozzle cap 6 fitted on the nozzle member 2. A nozzle hole 231 of the nozzle member 2 is covered with a hydrophilic filer 3, and a top wall of the nozzle member 2 is provided with an air hole 24 covered with a hydrophobic filter 4. The nozzle member 2 may be provided with a filter-mounting member 8 for attachment of the filters. Also, the nozzle member 2 may be provided with a flow control member that controls air flowing into the container body through the air hole.Type: GrantFiled: April 4, 2003Date of Patent: June 5, 2007Assignees: Nipro Corporation, Wakamoto Pharmaceutical Co., Ltd.Inventors: Tomohiko Kubo, Ikuko Asada
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Patent number: 7213702Abstract: A bag-shaped drug container comprises a bag-shaped container body made of a flexible film, and a mouth provided at one end of the container body. The mouth is provided on a side of an open end thereof with a Luer locking means to liquid-tightly connect it with a tip of a syringe, and closed by a closing means such as cap or a male Luer portion.Type: GrantFiled: November 1, 2002Date of Patent: May 8, 2007Assignee: Nipro CorporationInventors: Hiroaki Takimoto, Kenji Omori, Minoru Honda, Hitoshi Futagawa
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Patent number: 7207970Abstract: A filling/discharge port 10 which includes a port cap 20, a plug 40 which is slidably fitted in the inside of the port cap 20, and a plug cap 50 which is removably fitted to the tip of the plug 40 is provided for use in a liquid medicament containing chamber 563 of a container body 560 which is partitioned into a plurality of chambers 562 and 563 via a partitioning portion 561 which allows communication when the internal pressure of the container body 560 is increased, and the plug 40 is slidable from a closed position to a discharge position owing to an increase in the internal pressure. The filling/discharge port 10 reliably prevent medicaments in a medical container which contains a plurality of medicaments from being administered to a patient without being mixed so that they can be mixed during use.Type: GrantFiled: June 25, 2004Date of Patent: April 24, 2007Assignee: Nipro CorporationInventor: Mitsuru Hasegawa
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Patent number: 7201275Abstract: A PTP constructed so that when the PTP is divided into a section having one or a plurality of pocket portions, a person can discriminate between the top, bottom, right and left sides of this section in the planar direction and a visually handicapped person can correctly identify the direction of medicament identifying means provided on the section. The PTP includes a flexible sheet having a pocket portion containing a tablet T, and a metal foil adhered to the flexible sheet to hermetically seal the pocket portion containing the tablet T, and the PTP is dividable into sections including a plurality of pocket portions by a dividing line. An unevenness serving as medicament identifying means is provided on a top surface of a pocket portion, and arcs are respectively formed on the dividing line on the sides so that the shapes of all the divided sections become the same.Type: GrantFiled: July 8, 2004Date of Patent: April 10, 2007Assignee: Nipro CorporationInventors: Sachiko Nakagawa, Yoshihisa Hama, Yasuhiro Tsukamasa, Susumu Kimura, Takafumi Araki
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Patent number: D540467Type: GrantFiled: August 30, 2005Date of Patent: April 10, 2007Assignee: Nipro CorporationInventor: Satoru Mori
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Patent number: D540468Type: GrantFiled: August 30, 2005Date of Patent: April 10, 2007Assignee: Nipro CorporationInventor: Satoru Mori
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Patent number: D542413Type: GrantFiled: August 30, 2005Date of Patent: May 8, 2007Assignee: Nipro CorporationInventor: Satoru Mori