Abstract: A blood circuit connector includes: a main body having a cylindrical shape and provided with a first opening end and a second opening end; a plug having a bottomed cylindrical shape and detachably attached to the first opening end; and a connection part configured to connect the main body and the plug. The plug includes a side wall loosely fitted to an outer circumferential surface of the first opening end. The connection part includes a curved part expanding in a direction away from the main body. In a state where the plug is attached to the first opening, the curved part is pushed in a direction approaching the outer circumferential surface of the main body such that the curved part extends, thereby cancelling a loosely fitted state between the side wall and the outer circumferential surface, so as to remove the plug from the first opening end.

Abstract: An electrocardiograph measures an electrocardiac signal by processing electric signals detected by bioelectrode pads. The bioelectrode pads each includes a plurality of sheets of electrodes disposed by being stacked on each other; conductive gel sheets disposed alternately with the sheets of electrodes and interposed between the electrodes; and a dynamic pressure stabilizing plate. The electrocardiograph includes a first differential circuit for obtaining an electrocardiac source signal by taking the difference between signals each obtained from any one of the electrodes of each of two bioelectrode pads; a second differential circuit for obtaining a body motion noise signal by taking the difference between signals obtained from any two of the electrodes of each of said two bioelectrode pads; and a body motion noise removing circuit for removing the low frequency components of the body motion noise signal of each of said two bioelectrode pads from the electrocardiac source signal.

Abstract: A blood flow meter capable of measuring the flow rate of the blood flow with high accuracy in a blood vessel of a living body is provided. An element holding body having a tubular shape and having an outer diameter smaller than or equal to the outer diameter of a hollow shaft, which has flexibility and is insertable into a blood vessel, is provided on the distal side of the shaft so as to be coaxial with the shaft. A flow rate sensor is accommodated in the element holding body. The flow rate sensor has a measurement element in which a nickel wire is spirally wound to be formed into a coil shape so that adjacent nickel wires are not in contact with each other and are insulated. A thermal conductive insulating member is provided between the flow rate sensor and the element holding body in the element holding body and the flow rate sensor is fixed in the element holding body by the insulating member.

Abstract: A foreign matter detecting apparatus includes an oscillating unit, an optical system, a receiving unit, a scanning mechanism, and an operator. The oscillating unit generates a terahertz pulse wave and emits the terahertz pulse wave as irradiation light. The optical system guides the irradiation light to the first part of the container and condenses reflected light from the container. The receiving unit outputs a signal corresponding to the condensed reflected light and also measures an echo. The scanning mechanism scans a position of the irradiation light guided on the first part in a two-dimensional manner. The operator detects foreign matter in powder in a container based on at least one of a time waveform signal, a reflection image, a power spectrum, a tomographic image, and a frequency image. The time waveform signal is output from the receiving unit in chronological order.

Abstract: A triaxial acceleration sensor and a triaxial angular rate sensor are mounted on each of the lower limb portions on both sides of one joint among joints constituting a part of one lower limb of a subject. The acceleration and angular rate of each lower limb portion are measured by the triaxial acceleration sensor and triaxial angular rate sensor while the subject is walking. The orientations of each lower limb portion while walking are calculated on the basis of the measured acceleration and angular rate. A three-dimensional model including the motion trajectory of one joint is constructed by linking the lower limb portions in the calculated orientation to each other. The angle formed by the acceleration vector of one joint when the heel strikes the ground to the movement trajectory in the sagittal plane is calculated as a gait parameter.

Abstract: The invention provides a blood purifier which shows a decreased amount of hydrogen peroxide extracted from its selectively permeable separation membranes, and thus is highly reliable in its safety in use for hemecatharysis. The blood purifier comprises selectively permeable separation membranes as a main component and is characterized in that the amount of hydrogen peroxide which is extracted from the selectively permeable separation membrane removed from the blood purifier after 3 months or longer has passed since the sterilization of the blood purifier by exposure to a radioactive ray and/or an electron ray is not larger than 10 ppm.

Abstract: Objects of the invention are to provide a blood purifier package which shows a less increase in the amounts of extracts from the materials of its blood purifier, particularly of its selective permeable separation membranes, attributed to the deterioration of the same materials with time after exposure to a radioactive ray or an electron ray, and which is therefore highly reliable in safety in use for hemocatharsis, and to provide a process for manufacturing the same. The present invention relates to a blood purifier package obtained by packing a blood purifier which comprises selectively permeable separation membranes as a main component, and this blood purifier package is characterized in that the blood purifier is packed and sealed together with an oxygen scavenger in a packaging material capable of shutting out an external air and a water vapor, under a condition of a relative humidity of above 40% RH at 25° C.

Abstract: There is provided a means which carries out a fire-blast treating effectively upon removing a deteriorated region caused by processing in a process of producing a glass vessel. In a process of producing a glass vessel by fire-blast treating an internal surface 10 of a preform of the glass vessel with a flame from a burner 30 so as to produce the glass vessel, said fire-blast treating is carried out such that a temperature of an outer surface portion of the preform which portion is opposed to the deteriorated region caused by processing is between 650° C. and 800° C. when the flame is scanned along the internal surface of the preform toward an opening of the preform.

Abstract: To prevent a user from accidentally pricking the user with a hollow needle when separating blood components using a syringe and a connection device. A blood component separation apparatus has three syringes and a connection device. The connection device is attached to one syringe and is inserted into other syringes. The connection device has a first member to which a base end of a hollow needle is joined and a second member which is connected to the first member in such a manner as to be able to move relative to the first member. The second member is moved back and forth between a first position where a tip of the hollow needle is accommodated and a second position where the tip of the hollow needle is exposed. The second member has elastic portions which are elastically deformed in the movement from the first position to the second position. The elastically deformed elastic portions elastically energize the second member at the second position to the first position side with respect to the first member.

Abstract: A drug delivering apparatus includes a drug container, a pre-filled syringe including a cylindrical container having a nozzle portion and an injection needle attachment portion, and a connecting tool configured to allow communication between the inside of the cylindrical container and the inside of the drug container. The connecting tool further includes a nozzle insertion portion. The pre-filled syringe further includes a cap member configured to be detachably fitted on the injection needle attachment portion, the cap member having an opening into which the nozzle insertion portion can be inserted. The injection needle attachment portion has a guiding groove in the inner periphery thereof. In the state where the cap member is fitted on the injection attachment portion, at least a part of the edge of the opening is located on the inner side relative to the bottom portion of the guiding groove.

Abstract: The present invention relates to an oral film preparation obtained by spreading a solution containing a high potency drug and a film-forming polymer and then drying the solution, and a method for preparing an oral film preparation containing a high potency drug, said method comprising spreading a solution containing the high potency drug and a film-forming polymer and then drying the same, and a package obtained by (a) packaging the oral film preparation in a packaging material and, after nitrogen substitution, sealing the packaging material, and/or (b) sealing the oral film preparation together with a deoxidant in a packaging material. Provided are an oral film preparation that contains a high potency drug and has excellent content uniformity, a method for easily preparing an oral film preparation that contains a high potency drug and has excellent content uniformity, and a highly stable package that contains the oral film preparation.

Abstract: Provided is a stent of a novel structure with which deflection of a line-shaped body during expansion is prevented and a substantially uniform expansion is achieved over an entire length thereof, and with which, after implantation, stent fracture and damage of body tissue can be prevented by the stent exhibiting a superior pliability and conformability to a shape of a somatic lumen. A stent having a cylindrical peripheral wall formed with a line-shaped body that extends in a helical form in a circumferential direction while reciprocating in an axial direction at a given amplitude. In the stent, connecting parts are formed to link portions of the line-shaped body that are adjacent in the axial direction, and a friable part is provided to rupture itself by being implanted in the somatic lumen and release a link made by the connecting parts.

Abstract: In an indwelling needle assembly, a safety mechanism part is provided with an outer-needle-hub engaging part to be engaged with an outer needle hub, and an engaging-part opposing wall. Relative rotation of the outer-needle-hub engaging part and the engaging-part opposing wall is restricted, and at least one of the outer-needle-hub engaging part and the engaging-part opposing wall displaces integrally with urging parts. When an inner needle is pulled out of the outer needle hub, a block part engaged with the inner needle through an inner-needle engaging part is moved relative to the urging parts and forced to a non-contact state, and the urging parts displace in a direction approaching the inner needle, thereby preventing a needle tip of the inner needle from protruding from the safety mechanism part and releasing engagement of the outer needle hub with the safety mechanism part.

Abstract: Provided is a new balloon catheter enabling formation of, with high dimensional accuracy and excellent shape adaptability with respect to a balloon, an additional structure such as a blade and/or a reinforcement member on the balloon. The balloon catheter includes a shaft and an expandable/contractible balloon on the distal end side of the shaft, with an additional structure having a prescribed pattern being formed through electroforming or the like directly onto an inner circumferential surface and/or an outer circumferential surface of the balloon.

Abstract: The present invention relates to a medical dermatological preparation for external use comprising an active drug, polyoxyethylene arachyl ether, stearyl alcohol, a liquid oily ingredient, a moisturizing ingredient and water, and provides a medical dermatological preparation for external use, which reduces occurrence or degree of a side effect such as skin irritation in the medical dermatological preparation for external use. The present invention provides particularly a medical dermatological preparation for external use, which comprises adapalene and reduces occurrence and degree of a side effect such as skin irritation.

Abstract: A gasket includes a flexible packing portion having a recess attached to a coupler of a plunger rod, and a core member harder than the packing portion. The recess has an internal circumferential surface with an internally threaded portion capable of being screwed on and thus engaging with an externally threaded portion provided on an external circumferential surface of the coupler. The core member has a helical shape defining the internal circumferential surface of the recess and the internally threaded portion provided on the internal circumferential surface. The packing portion defines a sliding surface brought into contact with an inner circumferential surface of a barrel, and the packing portion also covers an outer circumferential surface of the core member.

Abstract: A method for producing a vial with low alkali elution by removing a deteriorated region caused by processing on an internal surface of a vial is disclosed. The method involves forming vials from borosilicate glass tubes including a first step of forming a borosilicate glass tube into a cup-shaped body by formation of a bottom of a vial, and a second step of forming the cup-shaped body into the vial by formation of a mouth of the cup-shaped body.

Abstract: A method for producing a vial with low alkali elution by removing a deteriorated region caused by processing on an internal surface of a vial is disclosed. The method involves forming vials from borosilicate glass tubes including a first step of forming a borosilicate glass tube into a cup-shaped body by formation of a bottom of a vial, and a second step of forming the cup-shaped body into the vial by formation of a mouth of the cup-shaped body.

Abstract: A puncture needle includes a needle tube 1 provided with a spiral groove 3 and wall surfaces 3a and 3b of the spiral groove 3 serve as a surface for reflecting ultrasonic waves. The spiral groove is formed on the peripheral surface of the needle tube such that a grinding stone 2 is brought into contact with the peripheral surface of the needle tube while the needle tube 1 is being moved in its axial direction and rotated. The wall surfaces of the spiral groove formed on the needle tube serve as a reflection surface to change the orientation of the reflection surface in the axial direction of the needle tube according to change in position of the spiral. Therefore, even if a direction in which an ultrasonic wave is applied to the puncture needle is fixed, any portion of the reflection surface changing in orientation can become a surface for reflecting well ultrasonic waves, so that good ultrasonic waves can be obtained.