Patents Assigned to Research Triangle Institute
  • Patent number: 10481070
    Abstract: Sample monitoring and flow control systems and methods are disclosed for monitoring of airborne particulates. A system may include a particle collection filter. The system also includes a fluid moving device for moving a sample through the particle collection filter. Further, the system includes a light source configured to direct irradiating light towards the particle collection filter. The system also includes a light detector positioned to receive the irradiating light passing through the particle collection filter and configured to generate a signal representative of an amount of the received light. Further, the system includes a controller configured to receive the signal and to control the fluid moving device based on the amount of the received light.
    Type: Grant
    Filed: April 30, 2019
    Date of Patent: November 19, 2019
    Assignee: Research Triangle Institute
    Inventors: Anthony Clint Clayton, Howard Jerome Walls, David S. Ensor, Andrei Yurievich Khlystov
  • Publication number: 20190336950
    Abstract: The present disclosure provides perovskite catalytic materials and catalysts comprising platinum-group metals and perovskites. These catalysts may be used as oxygen storage materials with automotive applications, such as three-way catalysts. They are also useful for water or CO2 reduction, or thermochemical energy storage.
    Type: Application
    Filed: November 14, 2017
    Publication date: November 7, 2019
    Applicant: Research Triangle Institute
    Inventors: Qinghe ZHENG, Marty LAIL, Kelly E. AMATO
  • Patent number: 10421894
    Abstract: The present disclosure relates to delivery and release systems, such as core-shell particles. An exemplary composition according to the disclosure can include a degradable polymeric shell surrounding a core that includes a crosslinker, which can encompass a metal, such as chromium. The core-shell particles can be provided with a gel-forming polymer, such as a polyacrylamide, into a subterranean reservoir having conditions such that the shell of the core-shell polymer degrades, and the so-released metal is effective to at least partially crosslink the gel-forming polymer to form a gel. The so-formed gel can be effective to control water flow through the subterranean reservoir, such as in relation to a waterflood of the reservoir.
    Type: Grant
    Filed: June 27, 2017
    Date of Patent: September 24, 2019
    Assignee: Research Triangle Institute
    Inventors: Leah Marie Johnson, Ginger Denison Rothrock, Chasity Antoninette Norton, Nicolas Daniel Huffman, Jeffrey Brent Mecham
  • Patent number: 10414649
    Abstract: Acid gas compounds are removed from a process gas such as, for example, syngas or natural gas, by flowing a feed gas into a desulfurization unit to remove a substantial fraction of sulfur compounds from the feed gas and flowing the resulting desulfurized gas into a CO2 removal unit to remove a substantial fraction of CO2 from the desulfurized gas.
    Type: Grant
    Filed: October 20, 2015
    Date of Patent: September 17, 2019
    Assignee: Research Triangle Institute
    Inventors: David L. Denton, Raghubir P. Gupta, Brian S. Turk, Vijay Gupta, Himanshu Paliwal
  • Publication number: 20190263781
    Abstract: Potent opioid receptor antagonists of formula (I) and their use as pharmacotherapies for treating depression, anxiety, schizophrenia, eating disorders, and addiction to cocaine, methamphetamine, nicotine, alcohol, and opiates are disclosed. More specifically, the disclosure provides potent and selective kappa opioid receptor antagonist compounds, pharmaceutical compositions of those compounds and uses of those compounds to ameliorate or treat addictions, eating disorders, etc.
    Type: Application
    Filed: September 15, 2017
    Publication date: August 29, 2019
    Applicant: Research Triangle Institute
    Inventors: Frank Ivy Carroll, Chad M. Kormos, Pauline W. Ondachi, Scott P. Runyon, Hernan A. Navarro, James B. Thomas, S. Wayne Mascarella
  • Patent number: 10378042
    Abstract: An aerosol collection system and method. The system includes a bio-aerosol delivery device configured to supply bioparticles in a gas stream, a moisture exchange device including a partition member coupled to the gas stream and configured to humidify or dehumidify the bioparticles in the gas stream, and an aerosol collection medium downstream from the moisture exchange device and configured to collect the bioparticles. The method includes delivering bioparticles in a gas stream, humidifying or dehumidifying the bioparticles in the gas stream by transport of water across a partition member and into a vapor phase of the gas stream, and collecting the bioparticles by a collection medium.
    Type: Grant
    Filed: February 19, 2013
    Date of Patent: August 13, 2019
    Assignee: Research Triangle Institute, Inc.
    Inventors: David S. Ensor, Howard Jerome Walls, Karin K. Foarde, Susanne Vera Hering, Steven Russel Spielman
  • Patent number: 10377718
    Abstract: This disclosure is directed to agonists of the apelin receptor (APJ) and uses of such agonists.
    Type: Grant
    Filed: June 5, 2015
    Date of Patent: August 13, 2019
    Assignee: Research Triangle Institute
    Inventors: Scott P. Runyon, Rangan Maitra, Sanju Narayanan, James Barnwell Thomas
  • Patent number: 10345216
    Abstract: Sample monitoring and flow control systems and methods are disclosed for monitoring of airborne particulates. A system may include a particle collection filter. The system also includes a fluid moving device for moving a sample through the particle collection filter. Further, the system includes a light source configured to direct irradiating light towards the particle collection filter. The system also includes a light detector positioned to receive the irradiating light passing through the particle collection filter and configured to generate a signal representative of an amount of the received light. Further, the system includes a controller configured to receive the signal and to control the fluid moving device based on the amount of the received light.
    Type: Grant
    Filed: August 20, 2015
    Date of Patent: July 9, 2019
    Assignee: Research Triangle Institute
    Inventors: Anthony Clint Clayton, Howard Jerome Walls, David S. Ensor, Andrei Yurievich Khlystov
  • Patent number: 10294427
    Abstract: This invention is directed to the discovery of a reactive catalytic fast pyrolysis (RCFP) process utilizing hydrogen at low pressures.
    Type: Grant
    Filed: September 11, 2014
    Date of Patent: May 21, 2019
    Assignee: Research Triangle Institute
    Inventors: Matthew Von Holle, John R. Carpenter, David C. Dayton
  • Patent number: 10286383
    Abstract: This invention is directed to novel mixed transition metal iron (II/III) catalysts for the extraction of oxygen from CO2 and the selective reaction with organic compounds.
    Type: Grant
    Filed: November 9, 2017
    Date of Patent: May 14, 2019
    Assignee: Research Triangle Institute
    Inventors: Jian-ping Shen, Marty Lail, Brian Turk, Paul D. Mobley, Jason S. Norman, Laura Douglas, Jonathan Peters
  • Patent number: 10265677
    Abstract: A mixed salt composition adapted for use as a sorbent for carbon dioxide removal from a gaseous stream is provided, the composition being in solid form and including magnesium oxide, an alkali metal carbonate, and an alkali metal nitrate, wherein the composition has a molar excess of magnesium characterized by a Mg:X atomic ratio of at least about 3:1, wherein X is the alkali metal. A process for preparing the mixed salt is also provided, the process including mixing a magnesium salt with a solution comprising alkali metal ions, carbonate ions, and nitrate ions to form a slurry or colloid including a solid mixed salt including magnesium carbonate; separating the solid mixed salt from the slurry or colloid to form a wet cake; drying the wet cake to form a dry cake including the solid mixed salt; and calcining the dry cake to form a mixed salt sorbent.
    Type: Grant
    Filed: October 19, 2017
    Date of Patent: April 23, 2019
    Assignee: Research Triangle Institute
    Inventors: Jian-Ping Shen, Luke James Ivor Coleman, Marty Alan Lail, Raghubir Prasad Gupta, Brian Scott Turk
  • Patent number: 10264669
    Abstract: A flexible electronic assembly includes a flexible current-carrying device, an electrically insulating flexible substrate, and an electronic device embedded in the substrate. The electronic device is mounted face-down on the current-carrying device such that a contact side or component side of the electronic device faces the current-carrying device and is positioned at an interface between the current-carrying device and the substrate. The current-carrying device, substrate, and electronic device are co-planar at the interface. This configuration enables the flexible electronic assembly to have an ultra-thin thickness, for example on the order of micrometers.
    Type: Grant
    Filed: April 28, 2016
    Date of Patent: April 16, 2019
    Assignee: Research Triangle Institute
    Inventors: Jay Lewis, Dorota Temple, Erik Vick, Ethan Klem
  • Patent number: 10232344
    Abstract: Solid sorbent materials have been prepared by combining polyethyleneimine (PEI) with silica precursors. The solid sorbent materials can be used, for example, for acid gas separation, gas purification, and water purification applications. Advantageously, such materials can be water stable and the capacity of such solid sorbent materials does not diminish substantially after repeated use and regeneration.
    Type: Grant
    Filed: July 14, 2015
    Date of Patent: March 19, 2019
    Assignee: Research Triangle Institute
    Inventors: Mustapha Soukri, Luke Coleman, Marty Lail
  • Patent number: 10208331
    Abstract: A bioparticle collection device and an aerosol collection system. The bioparticle collection device includes a collection medium including a plurality of fibers formed into a fiber mat and configured to collect bioparticles thereon, and includes a viability enhancing material provider disposed in a vicinity of the plurality of fibers and configured to provide a viability enhancing material to the collected bioparticles to maintain viability of the bioparticles collected by the fiber mat. The aerosol collection system includes an aerosol pumping device configured to entrain particles in an gas stream, an aerosol saturation device configured to saturate the particles in the gas stream with a biocompatible liquid, and an aerosol collection medium downstream from the aerosol saturation device and including a plurality of fibers formed into a fiber mat for collection of the saturated aerosol particles.
    Type: Grant
    Filed: April 27, 2018
    Date of Patent: February 19, 2019
    Assignee: Research Triangle Institute
    Inventors: David Samuel Ensor, Howard Jerome Walls, Karin K. Foarde
  • Patent number: 10188973
    Abstract: A filtration device including a base filtration material having openings for fluid flow there through and a filtration medium. The filtration medium includes a plurality of patterned nanofibers formed on the base filtration material. The filtration medium has a figure of merit greater than 30 kPa?1, where the figure of merit is given by ?Log (Pt)/?P, where Pt is the fractional penetration of a specific aerosol particle diameter and ?P is a pressure drop across the filtration medium corresponding to a face velocity of 5.3 cm/s and particle size of 0.3 microns.
    Type: Grant
    Filed: December 6, 2013
    Date of Patent: January 29, 2019
    Assignee: Research Triangle Institute
    Inventors: Anthony Clint Clayton, Howard Jerome Walls, Adam Joseph Rieth, David Samuel Ensor
  • Patent number: 10166503
    Abstract: This invention is directed to methods and systems for controlling water in acid gas removal processes comprising the steps of a) treating the gas stream in an absorption zone with the NAS absorption liquid; b) direction the acid gas-loaded NAS absorption liquid to a regeneration zone; c) directing the regenerated NAS absorption liquid to step a); and d) controlling the first and second set of conditions.
    Type: Grant
    Filed: February 13, 2015
    Date of Patent: January 1, 2019
    Assignee: Research Triangle Institute
    Inventors: Luke Coleman, Marty Lail, Kelly E. Amato, Jak Tanthana
  • Publication number: 20180325781
    Abstract: The disclosure provides biocompatible dental material that is moldable and biodegradable and provides sustained and/or controlled delivery of one or more local anesthetics within a dental cavity or space. Such dental material is customizable for the size and shape needed for a particular patient or particular application. The dental material may also provide customizable sustained and/or controlled delivery of one or more local anesthetics.
    Type: Application
    Filed: March 12, 2018
    Publication date: November 15, 2018
    Applicants: Research Triangle Institute, The University of North Carolina at Chapel Hill
    Inventors: Leah Marie Johnson, Ginger Denison Rothrock, Sarah Dorothy Shepherd, Sandra Cordel O'Buckley, Andrea Gail Neely
  • Patent number: 10099165
    Abstract: A filtration device including a contoured support having 1) an interior surface, 2) an outside peripheral surface spaced farther from a center of the contoured support than the interior surface, and 3) a rim enclosed and sealed to a perimeter of the contoured support. The filtration device includes macroscopic openings in the contoured support extending from the interior surface to the outside peripheral surface, and a plurality of nanofibers having diameters less than 1 micron. The nanofibers are disposed on the outside peripheral surface of the contoured support, and cover the macroscopic openings to form a filtration medium on the contoured support.
    Type: Grant
    Filed: December 21, 2015
    Date of Patent: October 16, 2018
    Assignee: Research Triangle Institute
    Inventors: Howard Jerome Walls, Randall J. Newsome, Anthony Clint Clayton, Robert W. Yaga, David Samuel Ensor
  • Patent number: 10100059
    Abstract: This disclosure is directed to agonists of the apelin receptor (APJ) and uses of such agonists.
    Type: Grant
    Filed: December 9, 2016
    Date of Patent: October 16, 2018
    Assignee: Research Triangle Institute
    Inventors: Scott P. Runyon, Rangan Maitra, Sanju Narayanan, James Barnwell Thomas, Kenneth S. Rehder, Srinivas Olepu
  • Patent number: 10065148
    Abstract: A solvent system for the removal of acid gases from mixed gas streams is provided. Also provided is a process for removing acid gases from mixed gas streams using the disclosed solvent systems. The solvent systems may be utilized within a gas processing system.
    Type: Grant
    Filed: March 1, 2013
    Date of Patent: September 4, 2018
    Assignee: Research Triangle Institute
    Inventors: Marty Lail, Luke Coleman