Patents Assigned to Research Triangle Institute
-
Patent number: 10018551Abstract: A particle detector includes a housing, a light source, and a photo-responsive material. The housing includes a sample inlet and a sample outlet, and encloses a detection cavity. The light source directs irradiating light along a longitudinal axis to particles of a sample fluid flowing in the detection cavity. The photo-responsive material surrounds at least a portion of the detection cavity, and receives measurement light propagating from the particles in a plurality of measurement light paths angled relative to the longitudinal axis. The particle detector may be utilized to measure scattered light and/or light emitted due to autofluorescence. Fluids sampled may include aerosols, bio-aerosols, and liquids.Type: GrantFiled: January 23, 2018Date of Patent: July 10, 2018Assignee: Research Triangle InstituteInventors: Howard Jerome Walls, Anthony Clint Clayton, Randall J. Newsome, Paul G. Hoertz
-
Patent number: 9994759Abstract: The present disclosure relates to delivery and release systems, such as core-shell particles. An exemplary composition according to the disclosure can include a carrier element forming an outer shell that defines an inner core. The core can include a reactive agent that is adapted to react with the shell, particularly at an inner interface of the shell with the core materials. The reaction can provide an inside-out degradation of the shell and release of one or more materials therein. The reactive agent may be separated from the shell, such as using a phase change material (PCM). Upon reaching specific environmental conditions, the PCM can change so as the release the reactive agent for reaction with the shell. The systems can be used in various methods to deliver a material to various environments, including underground reservoirs.Type: GrantFiled: August 12, 2014Date of Patent: June 12, 2018Assignee: Research Triangle InstituteInventors: Ginger D. Rothrock, Leah Marie Johnson
-
Patent number: 9988664Abstract: A bioparticle collection device and an aerosol collection system. The bioparticle collection device includes a collection medium including a plurality of fibers formed into a fiber mat and configured to collect bioparticles thereon, and includes a viability enhancing material provider disposed in a vicinity of the plurality of fibers and configured to provide a viability enhancing material to the collected bioparticles to maintain viability of the bioparticles collected by the fiber mat. The aerosol collection system includes an aerosol pumping device configured to entrain particles in an gas stream, an aerosol saturation device configured to saturate the particles in the gas stream with a biocompatible liquid, and an aerosol collection medium downstream from the aerosol saturation device and including a plurality of fibers formed into a fiber mat for collection of the saturated aerosol particles.Type: GrantFiled: November 24, 2015Date of Patent: June 5, 2018Assignee: Research Triangle InstituteInventors: David Samuel Ensor, Howard Jerome Walls, Karin K Foarde
-
Patent number: 9943466Abstract: The disclosure provides biocompatible dental material that is moldable and biodegradable and provides sustained and/or controlled delivery of one or more local anesthetics within a dental cavity or space. Such dental material is customizable for the size and shape needed for a particular patient or particular application. The dental material may also provide customizable sustained and/or controlled delivery of one or more local anesthetics.Type: GrantFiled: June 14, 2017Date of Patent: April 17, 2018Assignees: Research Triangle Institute, The University of North Carolina at Chapel HillInventors: Leah Marie Johnson, Ginger Denison Rothrock, Sarah Dorothy Shepherd, Sandra Cordel O'Buckley, Andrea Gail Neely
-
Patent number: 9944857Abstract: Described herein are processes for converting a biomass starting material (such as lignocellulosic materials) into a low oxygen containing, stable liquid intermediate that can be refined to make liquid hydrocarbon fuels. More specifically, the process can be a catalytic biomass pyrolysis process wherein an oxygen removing catalyst is employed in the reactor while the biomass is subjected to pyrolysis conditions. The stream exiting the pyrolysis reactor comprises bio-oil having a low oxygen content, and such stream may be subjected to further steps, such as separation and/or condensation to isolate the bio-oil.Type: GrantFiled: March 6, 2013Date of Patent: April 17, 2018Assignee: Research Triangle InstituteInventors: David C. Dayton, Raghubir P. Gupta, Brian S. Turk, Atish Kataria, Jian-Ping Shen
-
Patent number: 9915600Abstract: A particle detector includes a housing, a light source, and a photo-responsive material. The housing includes a sample inlet and a sample outlet, and encloses a detection cavity. The light source directs irradiating light to particles of a sample fluid flowing in the detection cavity. The photo-responsive material faces the detection cavity, and receives measurement light propagating from the particles in a plurality of measurement light paths angled relative to a longitudinal axis. The particle detector may be utilized to measure scattered light and/or light emitted due to autofluorescence. Fluids sampled may include aerosols, bio-aerosols, and liquids.Type: GrantFiled: February 19, 2016Date of Patent: March 13, 2018Assignee: Research Triangle InstituteInventors: Howard Jerome Walls, Anthony Clint Clayton, Randall J. Newsome, Paul G. Hoertz
-
Patent number: 9884313Abstract: This invention is directed to novel mixed transition metal iron (II/III) catalysts for the extraction of oxygen from CO2 and the selective reaction with organic compounds.Type: GrantFiled: July 31, 2014Date of Patent: February 6, 2018Assignee: Research Triangle InstituteInventors: Jian-ping Shen, Marty Lail, Brian Turk, Paul D. Mobley, Jason S. Norman, Laura Douglas, Jonathan Peters
-
Patent number: 9881905Abstract: An electronic package includes an adhesion layer between a first substrate and a second substrate. The adhesion layer is patterned to define openings aligned with through-substrate interconnects and corresponding bond pads. A conductive plane is formed between the first substrate and the second substrate, adjacent to the adhesion layer.Type: GrantFiled: April 20, 2015Date of Patent: January 30, 2018Assignee: Research Triangle InstituteInventors: Eric Paul Vick, Dorota Temple
-
Patent number: 9839875Abstract: A solvent system comprising an ionic Liquid formed from a relatively acidic component and a nitrogenous base for the removal of acid gases from mixed gas streams is provided. Also provided is a process for removing acid gases from mixed gas streams using the disclosed solvent system. The solvent system may be utilized within a gas processing system.Type: GrantFiled: September 2, 2011Date of Patent: December 12, 2017Assignee: Research Triangle InstituteInventors: Marty Lail, Luke Coleman
-
Patent number: 9808783Abstract: A mixed salt composition adapted for use as a sorbent for carbon dioxide removal from a gaseous stream is provided, the composition being in solid form and including magnesium oxide, an alkali metal carbonate, and an alkali metal nitrate, wherein the composition has a molar excess of magnesium characterized by a Mg:X atomic ratio of at least about 3:1, wherein X is the alkali metal. A process for preparing the mixed salt is also provided, the process including mixing a magnesium salt with a solution comprising alkali metal ions, carbonate ions, and nitrate ions to form a slurry or colloid including a solid mixed salt including magnesium carbonate; separating the solid mixed salt from the slurry or colloid to form a wet cake; drying the wet cake to form a dry cake including the solid mixed salt; and calcining the dry cake to form a mixed salt sorbent.Type: GrantFiled: July 19, 2013Date of Patent: November 7, 2017Assignee: Research Triangle InstituteInventors: Jian-Ping Shen, Luke James Ivor Coleman, Marty Alan Lail, Raghubir Prasad Gupta, Brian Scott Turk
-
Patent number: 9707510Abstract: A solvent system comprising a diluent and a nitrogenous base for the removal of CO2 from mixed gas streams is provided. Also provided is a process for removing CO2 from mixed gas streams using the disclosed solvent system. The solvent system may be utilized within a gas processing system.Type: GrantFiled: September 3, 2011Date of Patent: July 18, 2017Assignee: Research Triangle InstituteInventors: Marty Lail, Luke Coleman
-
Patent number: 9709541Abstract: A gas processing device includes a sample inlet defining a gas flow path into a housing, and a pump and a noise dampening device disposed in the housing. The noise dampening device includes an inlet chamber, an outlet chamber, and an elastomeric membrane interposed between and fluidly isolating the inlet chamber and the outlet chamber. The inlet chamber is interposed between the sample inlet and the pump inlet, and the outlet chamber communicates with the pump outlet.Type: GrantFiled: March 3, 2016Date of Patent: July 18, 2017Assignee: Research Triangle InstituteInventors: Charles E. Rodes, J. Randall Newsome
-
Publication number: 20170197198Abstract: Solid sorbent materials have been prepared by combining polyethyleneimine (PEI) with silica precursors. The solid sorbent materials can be used, for example, for acid gas separation, gas purification, and water purification applications. Advantageously, such materials can be water stable and the capacity of such solid sorbent materials does not diminish substantially after repeated use and regeneration.Type: ApplicationFiled: July 14, 2015Publication date: July 13, 2017Applicant: Research Triangle InstituteInventors: Mustapha Soukri, Luke Coleman, Marty Lail
-
Patent number: 9651313Abstract: A heat transfer system and related method of heat transfer is provided. The heat transfer system includes a tubular receiver positioned to receive heat from a heat source, the receiver comprising one or more enclosed tubes configured for gravity-driven flow of a particulate heat transfer fluid therethrough in a dense, unfluidized state having a particle volume fraction of at least about 25%; and at least one storage vessel in fluid communication with the tubular receiver and positioned to receive the heat transfer fluid therefrom, wherein the particulate heat transfer fluid includes a plurality of particles of a metal-containing material having a melting point of greater than 800 C, the heat transfer fluid being substantially free of a liquid component.Type: GrantFiled: October 9, 2013Date of Patent: May 16, 2017Assignee: Research Triangle InstituteInventors: James Arthur Trainham, Paul G. Hoertz, Christopher A. Bonino, John S. Newman
-
Patent number: 9617229Abstract: Provided herein are compounds and prodrugs and methods of preparation of compounds and prodrugs that are capable of functioning as releasers and/or uptake inhibitors of one or more monoamine neurotransmitters, including dopamine, serotonin, and norepinephrine. Also provided are pharmaceutical compositions comprising one or more of these compounds or prodrugs, which may further comprise one or more additional therapeutic agents. Also provided are methods of treatment of various conditions that may be responsive to modification of monoamine neurotransmitter levels, such as pre-obesity, obesity, addiction, and depression.Type: GrantFiled: May 20, 2011Date of Patent: April 11, 2017Assignees: Research Triangle Institute, The United States of America, As Represented by the Secretary Department of Health and Human ServicesInventors: Bruce E. Blough, Richard Rothman, Antonio Landavazo, Kevin M. Page, Ann Marie Decker
-
Patent number: 9576889Abstract: An electronic package may be fabricated by forming a first layer of insulating material on a first substrate such that the first layer covers a contact pad; forming an opening through the first layer to expose the contact pad; forming an un-patterned second layer on the first layer, the second layer including an adhesive having a viscosity less than that of the first layer, wherein a region of the second layer obstructs the contact pad; removing the region to re-expose the contact pad; aligning a second substrate with the first substrate such that a via of the second substrate is aligned with the opening; bonding the first substrate and the second substrate together at the second layer; and forming an interconnect in contact with the contact pad by depositing a conductive material through the via and the opening.Type: GrantFiled: June 25, 2013Date of Patent: February 21, 2017Assignee: Research Triangle InstituteInventor: Erik Paul Vick
-
Patent number: 9567841Abstract: The present disclosure relates to cementitious fluids comprising additives configured to form a permeable cement matrix after curing of the cement. The cementitious fluids can comprise a cementitious medium (e.g., a cement slurry) with a plurality of fibers dispersed therein. The fibers can be hollow, can be porous, and can be degradable. The cementitious fluid particularly can be used in methods of stimulating hydrocarbon bearing formations. Specifically, the cementitious fluid can be injected into the formation to form or enlarge a fracture, and the fluid can be cured to form the permeable cement matrix, said permeability arising from a loosely assembled tubular network and/or passages remaining after degradation of the fibers.Type: GrantFiled: June 29, 2015Date of Patent: February 14, 2017Assignee: Research Triangle InstituteInventors: Ginger D. Rothrock, Vikram Rao, Vijay Gupta, Leah Johnson
-
Patent number: 9562671Abstract: A lighting device (100) includes a housing (104) enclosing a housing interior (108), a light source (132), a light converter (136), and a color tuning device. The light source is configured for emitting a primary light beam of a primary wavelength (140) through the housing interior. The light converter includes a luminescent material (144) facing the housing interior and configured for emitting secondary light (156, 158) of one or more wavelengths different from the primary wavelength, in response to excitation by the primary light beam. The housing includes a light exit (124) for outputting a combination of primary light and secondary light. The color tuning device is configured for adjusting a position of the primary light beam relative to the luminescent material.Type: GrantFiled: August 19, 2011Date of Patent: February 7, 2017Assignee: Research Triangle InstituteInventor: James Lynn Davis
-
Patent number: 9562001Abstract: The invention provides bupropion analog compounds capable of inhibiting the reuptake of one or more monoamines. The compounds may selectively bind to one or more monoamine transporters, including those for dopamine, norepinephrine, and serotonin. Such compounds may be used to treat conditions that are responsive to inhibition of the reuptake of monoamines, including addiction, depression, and obesity.Type: GrantFiled: October 12, 2011Date of Patent: February 7, 2017Assignee: Research Triangle InstituteInventors: Frank Ivy Carroll, Bruce Edward Blough, Philip Abraham
-
Patent number: 9527823Abstract: The invention provides hydroxybupropion analogs capable of inhibiting the reuptake of one or more monoamines and/or acting as antagonists at nicotinic acetylcholine receptors. The compounds may selectively bind to one or more monoamine transporters, including those for dopamine, norepinephrine, and serotonin and/or may selectively bind to one or more nicotinic acetylcholine receptor subtypes. Such compounds may be used to treat conditions that are responsive to modification of monoamine levels and/or antagonism of nicotinic acetylcholine receptors, including drug dependency, depression, and obesity.Type: GrantFiled: November 10, 2014Date of Patent: December 27, 2016Assignees: Research Triangle Institute, Dignity Health, Virginia Commonwealth UniversityInventors: Frank Ivy Carroll, Bruce E. Blough, Hernan A. Navarro, S. Wayne Mascarella, Ana Zamfira Muresan, M. Imad Damaj, Ronald J. Lukas