Patents Assigned to Research Triangle Institute
  • Publication number: 20160158734
    Abstract: This invention is directed to novel mixed transition metal iron (II/III) catalysts for the extraction of oxygen from CO2 and the selective reaction with organic compounds.
    Type: Application
    Filed: July 31, 2014
    Publication date: June 9, 2016
    Applicant: Research Triangle Institute
    Inventors: Jian-ping SHEN, Marty LAIL, Brian TURK, Paul D. MOBLEY, Jason S. NORMAN, Laura DOUGLAS, Jonathan PETERS
  • Patent number: 9349970
    Abstract: A photodetector includes one or more photodiodes and a signal processing circuit. Each photodiode includes a transparent first electrode, a second electrode, and a heterojunction interposed between the first electrode and the second electrode. Each heterojunction includes a quantum dot layer and a fullerene layer disposed directly on the quantum dot layer. The signal processing circuit is in signal communication each the second electrode. The photodetector may be responsive to wavelengths in the infrared, visible, and/or ultraviolet ranges. The quantum dot layer may be treated with a chemistry that increases the charge carrier mobility of the quantum dot layer.
    Type: Grant
    Filed: April 16, 2014
    Date of Patent: May 24, 2016
    Assignee: Research Triangle Institute
    Inventors: Ethan Klem, John Lewis
  • Patent number: 9339195
    Abstract: An apparatus, system, and method are disclosed for detecting seizure symptoms in an individual 102. A sensor module 202 receives physiological data for an individual 102 from one or more sensors 110, 112, such as a heart activity sensor. A feature detection module 204 detects a predefined feature 500, 520, 530, 540 in the physiological data. The predefined feature 500, 520, 530, 540 is associated with a seizure or another medical condition. An alert module 206 broadcasts an alert in response to the feature detection module 204 detecting the predefined feature 500, 520, 530, 540.
    Type: Grant
    Filed: January 27, 2011
    Date of Patent: May 17, 2016
    Assignee: RESEARCH TRIANGLE INSTITUTE
    Inventors: Ann Pitruzzello, Barbara Kroner, Jamie Shorey, David C Strube
  • Publication number: 20160095854
    Abstract: Provided are opioid receptor antagonists represented by the formula (I): where R, Y3, R1, R2, R3, R4 and R5 are as defined herein.
    Type: Application
    Filed: December 14, 2015
    Publication date: April 7, 2016
    Applicant: RESEARCH TRIANGLE INSTITUTE
    Inventors: Frank I. CARROLL, Juan P. CUEVA, James B. THOMAS, S. Wayne MASCARELLA, Scott P. RUNYON
  • Patent number: 9304117
    Abstract: A gas processing device such as an aerosol exposure monitor is configured for acquiring chronic data, acute data, or both simultaneously, and may include a pump and a noise dampening device. The noise dampening device may include an elastomeric membrane between an inlet chamber and an outlet chamber. In another aspect, an aerosol exposure monitor may include an impactor, a collection filter, and a nephelometer that includes a sample chamber integrated with an aerosol flow path associated with the impactor and collection filter.
    Type: Grant
    Filed: October 26, 2012
    Date of Patent: April 5, 2016
    Assignee: Research Triangle Institute
    Inventors: Charles E. Rodes, J. Randall Newsome
  • Publication number: 20160076073
    Abstract: A bioparticle collection device and an aerosol collection system. The bioparticle collection device includes a collection medium including a plurality of fibers formed into a fiber mat and configured to collect bioparticles thereon, and includes a viability enhancing material provider disposed in a vicinity of the plurality of fibers and configured to provide a viability enhancing material to the collected bioparticles to maintain viability of the bioparticles collected by the fiber mat. The aerosol collection system includes an aerosol pumping device configured to entrain particles in an gas stream, an aerosol saturation device configured to saturate the particles in the gas stream with a biocompatible liquid, and an aerosol collection medium downstream from the aerosol saturation device and including a plurality of fibers formed into a fiber mat for collection of the saturated aerosol particles.
    Type: Application
    Filed: November 24, 2015
    Publication date: March 17, 2016
    Applicant: RESEARCH TRIANGLE INSTITUTE
    Inventors: David Samuel ENSOR, Howard Jerome WALLS, Karin K. FOARDE
  • Patent number: 9284322
    Abstract: Provided herein are compounds and methods of preparation of compounds that are capable of functioning as agonists or antagonists of a nicotinic receptor. Also provided are pharmaceutical compositions comprising one or more of these compounds, which may further comprise one or more additional therapeutic agents. Further provided are methods of treatment of various conditions that may be responsive to such activity at the nicotinic receptors, such as nicotine dependence.
    Type: Grant
    Filed: February 6, 2015
    Date of Patent: March 15, 2016
    Assignee: Research Triangle Institute
    Inventors: Frank Ivy Carroll, Pauline Wanjiku Ondachi
  • Patent number: 9273027
    Abstract: Provided are opioid receptor antagonists represented by the formula (I) where R, Y3, R1, R2, R3, R4 and R5 are as defined herein.
    Type: Grant
    Filed: October 12, 2010
    Date of Patent: March 1, 2016
    Assignee: RESEARCH TRIANGLE INSTITUTE
    Inventors: Frank I. Carroll, Juan P. Cueva, James B. Thomas, S. Wayne Mascarella, Scott P. Runyon
  • Publication number: 20160042826
    Abstract: An apparatus for use with a neutron source for producing reaction-product nuclei from reactant nuclei includes a plurality of reactant nuclei and a plurality of moderating nuclei. The reactant nuclei and the moderating nuclei are configured to increase the probability of neutron capture by reactant nuclei to achieve enhanced ratios of neutron capture by reactant nuclei to neutron source neutron production. Moderating nuclei and neutron reflection are used to minimize neutron leakage. Temperature control, including cryogenic temperature control, may be used to enhance the rate or probability of reactant nuclei neutron capture. The reactant nuclei may include molybdenum-98 and reaction-product nuclei may include technetium-99m.
    Type: Application
    Filed: August 6, 2015
    Publication date: February 11, 2016
    Applicant: Research Triangle Institute
    Inventor: Nicholas Guy Baldasaro
  • Patent number: 9257335
    Abstract: An electronic device includes a substrate including a front side, a back side, a thickness between the front side and back side, one or more front-side vias extending from the front side into a part of the thickness, and an interconnect via extending from the back side toward the front side; a contact pad on the front side and including one or more protrusions extending through corresponding front-side vias and into the interconnect via; and an interconnect extending through the interconnect via and into contact with the protrusion(s).
    Type: Grant
    Filed: September 4, 2013
    Date of Patent: February 9, 2016
    Assignee: Research Triangle Institute
    Inventors: Erik Vick, Garry Brian Cunningham, Dorota Temple
  • Publication number: 20160036974
    Abstract: Computer-implemented methods and computer-readable media are disclosed for processing call-for-service data to facilitate queries and reports to enhance usefulness of call-for-service data. In one embodiment, a computer-implemented method performable by a computer system includes receiving at a computer system data for a plurality of calls-for-service. Individual data for an individual call-for-service includes one or more fields storing information relating to the call-for-service. Based on the information stored within the one or more fields of the individual data, one or more supplemental classifiers are automatically identified. The one or more supplemental classifiers are associated with the individual data. The one or more supplemental classifiers associated with the individual data enable the individual call-for-service to be identified when the one or more supplemental classifiers match one or more specified criteria.
    Type: Application
    Filed: March 14, 2013
    Publication date: February 4, 2016
    Applicant: Research Triangle Institute
    Inventors: Kevin Jay Strom, Mark William Pope, Maurice A Martin, Christopher Michael Griggs, James IIIiad Rineer, Crystal Majors Daye
  • Patent number: 9228716
    Abstract: A fiber-based reflective lighting device and a housed lighting device. The fiber-based reflective lighting device which includes a source configured to generate a primary light, and a substrate having a nanocomposite mat of reflective fibers having a diameter less than 1,000 nm which diffusively reflects light upon illumination with at least the primary light. The nanocomposite mat includes a reflectance-enhancing coating conformally disposed around an outer surface of the fibers, having a refractive index different from the reflective fibers, and which increases a reflectance of the substrate in the visible spectrum. The lighting device includes a light exit configured to emanate the reflected light. The housed lighting device includes a housing, a source configured to generate primary light and direct the primary light into the housing, the reflective nanocomposite mat of reflective fibers, and a light exit in the housing configured to emanate the reflected light from the housing.
    Type: Grant
    Filed: June 1, 2012
    Date of Patent: January 5, 2016
    Assignee: RESEARCH TRIANGLE INSTITUTE
    Inventors: James Lynn Davis, Kimberly A. Guzan, Karmann C. Mills, Michael K. Lamvik, James F. Bittle, Laura Haines
  • Patent number: 9187480
    Abstract: The invention provides compounds capable of acting as antagonists at cannabanoid receptors according to the following formula: Such compounds may be used to treat conditions for which the cannabinoid receptor system has been implicated, such as obesity, liver disease, diabetes, pain, and inflammation.
    Type: Grant
    Filed: February 15, 2013
    Date of Patent: November 17, 2015
    Assignee: Research Triangle Institute
    Inventors: Rangan Maitra, Alan Bradley Fulp, Yanan Zhang, Herbert H. Seltzman
  • Publication number: 20150307786
    Abstract: A catalyst is described that is useful for catalytic pyrolysis of biomass to produce a pyrolysis product. The catalyst includes (i) matrix material comprising a support and/or binder, and (ii) at least one metal oxide on the matrix material, wherein the metal oxide comprises metal selected from the group consisting of tungsten, chromium, cobalt, molybdenum, nickel, and combinations thereof. Corresponding catalytic pyrolysis processes and catalytic pyrolysis apparatus are disclosed, in which the catalyst enables the production of low oxygen content, stable liquid intermediates that can be refined to make liquid hydrocarbon fuels.
    Type: Application
    Filed: December 4, 2013
    Publication date: October 29, 2015
    Applicant: RESEARCH TRIANGLE INSTITUTE
    Inventors: David C. Dayton, PhD, Maruthi Sreekanth Pavani, John R. Carpenter III, Matthew Von Holle
  • Publication number: 20150298036
    Abstract: A filtration device including a base filtration material having openings for fluid flow there through and a filtration medium. The filtration medium includes a plurality of patterned nanofibers formed on the base filtration material. The filtration medium has a figure of merit greater than 30 kPa?1, where the figure of merit is given by ?Log (Pt)/?P, where Pt is the fractional penetration of a specific aerosol particle diameter and ?P is a pressure drop across the filtration medium corresponding to a face velocity of 5.3 cm/s and particle size of 0.3 microns.
    Type: Application
    Filed: December 6, 2013
    Publication date: October 22, 2015
    Applicant: Research Triangle Institute
    Inventors: Anthony Clint CLAYTON, Howard Jerome WALLS, Adam Joseph RIETH, David Samuel ENSOR
  • Patent number: 9163995
    Abstract: Sub-arrays such as tiles or chips having pixel elements arranged on a routing layer or carrier to form a larger array. Through-chip vias or the like to the backside of the chip are used for connecting with the pixel elements. Edge features of the tiles may provide for physical alignment, mechanical attachment and chip-to-chip communication. Edge damage tolerance with minimal loss of function may be achieved by moving unit cell circuitry and the electrically active portions of a pixel element away from the tile edge(s) while leaving the optically active portion closer to the edge(s) if minor damage will not cause a complete failure of the pixel. The pixel elements may be thermal emitter elements for IR image projectors, thermal detector elements for microbolometers, LED-based emitters, or quantum photon detectors such as those found in visible, infrared and ultraviolet FPAs (focal plane arrays), and the like. Various architectures are disclosed.
    Type: Grant
    Filed: October 21, 2012
    Date of Patent: October 20, 2015
    Assignees: Santa Barbara Infrared, Inc., Research Triangle Institute, Indiana Integrated Circuits
    Inventors: Joseph Donald LaVeigne, John LaƱnon, Scott Goodwin, Jason Kulick
  • Patent number: 9150582
    Abstract: Neuropeptide S receptor antagonists are provided that bind in functional assays to neuropeptide S receptors; methods are provided for use of these antagonists in treatment of conditions or disease states that are ameliorated by blocking of the neuropeptide S receptor, including substance abuse and substance abuse relapse; and for use of neuropeptide S receptor antagonists in the manufacture of therapeutics and pro-drugs for therapeutics useful in disease states and conditions sensitive to binding of the neuropeptide S receptor.
    Type: Grant
    Filed: December 6, 2012
    Date of Patent: October 6, 2015
    Assignee: RESEARCH TRIANGLE INSTITUTE
    Inventors: Scott Runyon, Yanan Zhang, Carla Hassler, Brian Gilmour
  • Patent number: 9150581
    Abstract: Compounds and compositions for promoting smoking cessation or decreasing tobacco use or nicotine addiction are provided. The compounds are 2?-fluoro-3?-(substituted phenyl) deschloroepibatidine analogs. The compounds have been found to modulate neuronal nicotine acetylcholine receptors and are useful in methods for the treatment of conditions or disorders influenced by the modulation of neuronal nicotinic acetylcholine receptors.
    Type: Grant
    Filed: December 26, 2012
    Date of Patent: October 6, 2015
    Assignees: RESEARCH TRIANGLE INSTITUTE, THE REGENTS OF THE UNIVERSITY OF MICHIGAN, VIRGINIA COMMONWEALTH UNIVERSITY
    Inventors: Frank Ivy Carroll, Pauline Wanjiku Ondachi, Hernan A. Navarro, M. Imad Damaj, James H. Woods, Emily M. Jutkiewicz
  • Patent number: 9136794
    Abstract: An apparatus, system, and method are disclosed for modulating electric current. An electron source electrode provides a flow of electrons in a partial vacuum environment. An ionizable gas in the partial vacuum environment forms positively charged ion particles in response to impact with the electrons from the electron source electrode. Application of a bias voltage differential between a first bias electrode and a second bias electrode in the partial vacuum environment forms an electric field gradient in a path of the flow of electrons. A collector electrode in the partial vacuum environment collects more electrons than ion particles when a collector electrode input voltage is above a threshold, and collects more ion particles than electrons when the collector electrode input voltage is below the threshold.
    Type: Grant
    Filed: June 21, 2012
    Date of Patent: September 15, 2015
    Assignee: Research Triangle Institute, International
    Inventors: Brian Stoner, Jeffrey Piascik
  • Patent number: 9133128
    Abstract: The invention provides compounds capable of acting as antagonists at cannabanoid receptors according to the following formula: Such compounds may be used to treat conditions for which the cannabinoid receptor system has been implicated, such as obesity, liver disease, diabetes, pain, and inflammation.
    Type: Grant
    Filed: June 15, 2012
    Date of Patent: September 15, 2015
    Assignee: Research Triangle Institute
    Inventors: Alan Bradley Fulp, Rangan Maitra, Yanan Zhang, Herbert H. Seltzman