Abstract: An augmented reality (AR) device including at least one optical module is provided. Each of the at least one optical module sequentially includes a transparent display, a first lens, a second lens, and a third lens from a display side to an eye side. The first lens has a negative refractive power. The second lens has a negative refractive power. The third lens has a positive refractive power. The number of lenses of the optical module having refractive powers is three, wherein the transparent display of the optical module is configured to emit a light beam, and the light beam sequentially passes through the first lens, the second lens, and the third lens to be incident into a user's eyes at the eye side, so that an AR virtual image on the display side is seen by the eyes.

Abstract: The therapeutic effect of and/or prognosis after administration of an anti-VEGFR-2 antibody drug, in particular, ramucirumab can be predicted by measuring VEGF-A, VEGF-D, sVEGFR-2, SDF-1?, and/or cNRP1. Provided is a biomarker for predicting the effect of administration of the anti-VEGFR-2 antibody drug, in particular, ramucirumab, and a test method and a test kit using the marker.

Abstract: A method and system for gastric stimulation and imaging for a user. The system having an array of millimeter-sized gastric seeds implanted in a stomach area of a user. Each gastric seed is ultrasonically powered and communicates using a transducer, and the transducer has a recorder to measure a bioelectrical activity in the stomach area of the user. A wearable unit (WU) is worn or carried by the user, and the WU wirelessly powers the gastric seeds. The WU wirelessly communicates with the gastric seeds, and the gastric seeds communicate a parameter to the WU based on the bioelectrical activity. Received pulses by the seeds can be used to localize the position of the seeds and guide the wireless power/data transmission in a self-image-guided manner. A processing unit (PU) wirelessly communicates with the WU, and the WU communicates the parameters from the gastric seeds to the PU.

Abstract: Improved energy conservation, including realization of a ZNET (Zero Net Energy including Transportation) paradigm, can be encouraged by providing energy consumers with a holistic view of their overall energy consumption. Current energy consumption in terms of space heating, water heating, other electricity, and personal transportation can be modeled by normalizing the respective energy consumption into the same units of energy. In addition, the passive always-on electricity consumption caused by inactive devices that contributes to the baseload of a building can be identified and addressed by the consumer, as appropriate by expressing baseload as a compound value that combines constant always-on loads and regularly-cycling loads. The baseload is estimated as the peak occurrence in a frequency distribution of net load data, after which the always-on load can be determined by subtracting out any regularly-cycling loads.

Abstract: The present invention is directed to methods for detecting a colon cancer, methods for determining whether a colon cancer is stable or progressive, methods for determining a risk for disease relapse, and methods for determining a response by a subject having a colon cancer to a therapy.

Abstract: Synthesis of O-benzotriazole and O-imidazole synthons are described. Uses of synthons in synthesis of azapeptides and other peptidomimetics, azapeptides and other peptidomimetics synthesized from the synthons and uses of azapeptides and other peptidomimetics are also described.

Abstract: A switching device is disclosed. The switching device includes a spin-orbit coupling (SOC) layer, a pure spin conductor (PSC) layer disposed atop the SOC layer, a ferromagnetic (FM) layer disposed atop the PSC layer, and a normal metal (NM) layer sandwiched between the PSC layer and the FM layer. The PSC layer is a ferromagnetic insulator (FMI) is configured to funnel spins from the SOC layer onto the NM layer and to further provide a charge insulation so as to substantially eliminate current shunting from the SOC layer while allowing spins to pass through. The NM layer is configured to funnel spins from the PSC layer into the FM layer.

Abstract: Methods for enhancing recovery after an ischemic injury, including cerebral ischemia and stroke, by administration of therapeutic amounts of Domain V protein are described.

Abstract: A diesel engine high pressure SCR ventilation and voltage stabilisation system, comprising an SCR reactor (10), an air intake pipeline (20) and an exhaust pipeline (30) respectively connected to an air inlet and an exhaust outlet of the SCR reactor, a pressure difference sensing apparatus (40), and a control apparatus, a first control valve (21) being arranged on the air intake pipeline (20) and a second control valve (31) being arranged on the exhaust pipeline (30), and the control apparatus being connected to the pressure difference sensing apparatus (40), the first control valve (21), and the second control valve (31). The control apparatus controls the first and second control valves such that the pressure difference between the SCR reactor and the exhaust side of the diesel engine remains in a predetermined pressure difference range. The present system implements rapid ventilation and ensures precise control and stabilisation of pressure difference.

Abstract: Provided is a training method of a neural network that is applied to an audio signal encoding method using an audio signal encoding apparatus, the training method including generating a masking threshold of a first audio signal before training is performed, calculating a weight matrix to be applied to a frequency component of the first audio signal based on the masking threshold, generating a weighted error function obtained by correcting a preset error function using the weight matrix, and generating a second audio signal by applying a parameter learned using the weighted error function to the first audio signal.

Abstract: Systems and methods which provide data exchange using a distributed ledger, wherein data is exchanged off-chain and information for accessing the off-chain data is exchanged through the blockchain, are disclosed. Embodiments may provide a hybrid blockchain data exchange platform storing large amounts of data (e.g., IoT data) in a data server outside of the blockchain, wherein a data consumer may obtain data from the data server using a token obtained from the blockchain. Embodiments of a hybrid blockchain data exchange platform provide for accuracy and security of the data without requiring storage of the full contents of the data within the blockchain, and/or provide data exchange in which the irrefutability of the data exchanged is ensured.

Abstract: A system for transitioning a vehicle from an autonomous mode in response to a handover event, the system includes one or more processors and a memory device operably coupled with the one or more processors. The memory device stores a driver assessment module, an operational condition adjustment module, and a transitioning module. The driver assessment module configures the one or more processors to determine an ability level and a comfort level of a driver of the vehicle in response to the handover event. The operational condition adjustment module configures the one or more to adjust at least one operating condition of the vehicle to be within the ability level of the driver and comfort level. The transitioning module configures the one or more processors to transition the vehicle from the autonomous mode to a driver input mode.

Abstract: This document relates to materials and methods for treating cancer. For example, this document provides materials and methods for using PD-L1 targeting domains in bispecific chimeric polypeptides, chimeric transmembrane polypeptides, genetically modified viruses, nucleic acid vectors, and/or fusion-inducing cells to treat cancer.

Abstract: A tetracarbonyl cyclobutene dihydrate compound, having a chemical formula (I). A method of synthesizing the tetracarbonyl cyclobutene dihydrate compound, includes: a synthesis step, a separation step, and a purification step. The synthesis step includes: collecting and dissolving 0.5728 g of squaric acid, 2.7948 g of ammonium formate, and 0.0480 g of the palladium complex in 100 mL of anhydrous methanol, heating and stirring a resulting mixture to reflux for 48 hrs, and stopping the reaction. The separation step includes: performing column chromatography analysis on reaction products according to a volume ratio of dichloromethane to anhydrous methanol of 8:2, to obtain a target product. A method of using the tetracarbonyl cyclobutene dihydrate compound, includes: using tetracarbonyl cyclobutene dihydrate compound as a catalyst in addition reaction between ethyl pyruvate and nitromethane, where a conversion rate of ethyl pyruvate reaches 96.1%.

Abstract: Methods for rapid isolation of radionuclides (e.g., 68Ga) produced using a cyclotron and methods for recycling of the parent isotope (e.g., 68Zn) are disclosed. In one version of the method, a solution including a radionuclide (e.g., 68Ga) is created from a target including cations (e.g., 68Zn). The solution including the radionuclide is passed through a first column including a sorbent comprising a hydroxamate resin to adsorb the radionuclide on the sorbent, and the radionuclide is eluted off the sorbent. The cations (e.g., 68Zn) are recovered from a recovery solution that has passed through the first column by passing the recovery solution through a second column including a second sorbent comprising a cation exchange resin.

Abstract: The invention provides compositions and methods for disrupting preformed bacterial biofilm or preventing formation of bacterial biofilm. Also provided in the invention are methods and compositions for treating and preventing chronic rhinosinusitis. Such compositions and methods utilize one or more antibiotic compounds in combination with at least one phospholipid compound described herein.

Abstract: Multiple redundant harmonic drive motors on a rotor head actuate the angle of attack of rotor blades at the rotor blade roots, providing collective control that, in combination with a system for providing cyclic control on the rotor blades, eliminates the need for a swashplate, thereby advantageously reducing the weight and maintenance cost of a helicopter, increasing its reliability, and reducing its vulnerability to ballistic attack.

Abstract: The present invention refers to lambda integrases comprising at least one amino acid mutation at positions 43, 319 and 336 of the lambda integrase as set forth in SEQ ID NO: 1. The invention further refers to nucleic acid molecules comprising the nucleotide sequence encoding the mutant lambda integrase and to host cells containing these nucleic acid molecules. The invention also refers to methods of recombining a nucleic acid of interest into a target nucleic acid in the presence of the mutant lambda integrase and sequence specific recombination kits.

Abstract: Methods of detecting and, optionally, determining a level of incorporation of monolignol ester conjugates into lignin. The methods include derivatizing lignin to acylate at least a portion of free phenolic and aliphatic hydroxyls and to halogenate at least a portion of benzylic alcohols present in the lignin to yield derivatized lignin, treating the derivatized lignin with a reducing agent to cleave at least a portion of the derivatized lignin to yield lignin cleavage products, acetylating at least a portion of free hydroxyl groups in the lignin cleavage products with a labeled acetylation agent to yield labeled lignin fragments, and detecting the labeled lignin fragments.