Abstract: The present invention relates to a tricyclic compound used as a GPR84 antagonist, and in particular relates to a tricyclic compound having a structure shown in formula I, and tautomers, stereoisomers, hydrates, solvates, pharmaceutically acceptable salts or prodrugs thereof; the definitions of the ring Cy, L1, R1 are as described in the present invention; the tricyclic compound has significant GPR84 antagonism, good pharmaceutical developability and high safety.
Type:
Application
Filed:
June 21, 2022
Publication date:
August 29, 2024
Applicant:
Wuhan Humanwell Innovative Drug Research and Development Center Limited Company
Inventors:
Xuejun ZHANG, Yang ZANG, Wenjun WEI, Qun LI, Xin ZHAO, Qing XU, Ping NI, Li'e LI, Jun YANG
Abstract: Proposed are a personal mobility device system and a control method of a personal mobility device system. The personal mobility device system includes a boarding body having a seat that a user is capable of sitting on, and includes a moving body which is coupled to the boarding body and which has a driving force based on an electric power.
Type:
Application
Filed:
December 29, 2023
Publication date:
August 29, 2024
Applicant:
ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
Abstract: Provided is an operation method of a coherent optical reception system. The operation method includes the following configurations. A coherent optical receiver configured to receive light from at least two light sources; a local oscillator (LO) configured to transmit first LO light to the coherent optical receiver, and a polarization controller configured to transmit a signal for polarization control to the LO, wherein the polarization controller is configured to transmit a first control signal to the LO on the basis of a first reception signal, and the LO is configured to transmit second LO light to the coherent optical receiver on the basis of the first control signal.
Type:
Application
Filed:
February 27, 2024
Publication date:
August 29, 2024
Applicant:
ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
Abstract: Described are a water quality testing method and a water quality testing apparatus. The testing method includes: obtaining, in a first environment, a testing sample including a target testing object; selecting a reference object according to the testing sample, and respectively acquiring the chroma of the reference object in a second environment and in the first environment; constructing a correction model according to the chroma of the reference object in the second environment and in the first environment; obtaining the chroma of the testing sample in the first environment; according to the chroma of the testing sample in the first environment and the correction model, obtaining the chroma of the testing sample in the second environment; and according to a preset standard curve and the chroma of the testing sample in the second environment, obtaining the concentration of the target testing object in the testing sample.
Type:
Application
Filed:
May 25, 2022
Publication date:
August 29, 2024
Applicants:
CHINA PETROLEUM & CHEMICAL CORPORATION, SINOPEC RESEARCH INSTITUTE OF SAFETY ENGINEERING CO., LTD.
Inventors:
Junjie FENG, Bing SUN, Huiyun JIANG, Yan JIN, Anshan XIAO, Haozhi WANG, Shiqiang WANG
Abstract: The present disclosure provides, in various aspects, engineered alcohol tolerant yeast and methods of producing high concentrations of biofuels and bioplastics from toxic feedstocks.
Type:
Application
Filed:
June 23, 2022
Publication date:
August 29, 2024
Applicants:
Massachusetts Institute of Technology, Whitehead Institute for Biomedical Research
Inventors:
Felix Lam, Gregory Stephanopoulos, Gerald Fink
Abstract: The present invention relates to oligonucleotides that maintain a Toll-Like Receptor 7 (TLR7) response and/or which potentiate Toll-Like Receptor 8 (TLR8) sensinq.
Abstract: An example device for detecting intravenous (IV) infiltration by identifying leaks and swelling at the patient skin. The device uses skin swelling to displace alignment of overlapping layers to produce a pattern or indication of swelling. Leakage is detected through the use of a conduit to wick liquid away from an insertion site and react with a dye or reagent to produce a color change that makes a clear visible indication of leaking. The detection methods provide visible markers without occluding visibility of the insertion site for the IV therapy.
Type:
Application
Filed:
May 27, 2022
Publication date:
August 29, 2024
Applicants:
University of Washington, Seattle Children’s Research Hospital (DBA Seattle Children’s Research Institute)
Inventors:
Krystle PEREZ, Elena M. BOSQUE, Sienna RICE, Gregory Charles VALENTINE, Eric J. SEIBEL, Leonard Y. NELSON, Jung Woong Samuel SEO, Benneth SALANGA, Kathleen KEARNEY, Liam BURK, Timothy Rex ROBINSON
Abstract: An optical pulse stretcher that stretches a pulse width of a pulse laser beam includes a polarizer configured to separate a component in a specific polarization direction of the pulse laser beam that has entered, a delay optical system including a plurality of mirrors through which the pulse laser beam reflected by or transmitted through the polarizer is propagated; and a first Faraday rotator that includes a first magnet and a first Faraday material and is disposed on an optical path of the delay optical system to rotate a polarization direction of the pulse laser beam.
Type:
Application
Filed:
May 7, 2024
Publication date:
August 29, 2024
Applicants:
Gigaphoton Inc., Inter-University Research Institute Corporation, National Institutes of Natural Sciences
Abstract: A method and system for detection of retinal hemorrhages using head computed tomography incorporating deep learning includes obtaining a patient head computed tomography image, segmenting globes using a deep-learning model, rotating the scans using the angle between globes, cropping and masking the globes, and stacking the globes to form 3D individual images that are analyzed for presence of retinal hemorrhage.
Type:
Application
Filed:
January 24, 2024
Publication date:
August 29, 2024
Applicant:
University of Tennessee Research Foundation
Inventors:
Nadeem Shafi, Fatma Gunturkun, Berna Bakir Batu
Abstract: One form of a metallic particle detection system detects automatically, through analysis of image data from a first sensor, a foreign metallic particle in or on an active material layer of an electrode strip moving between a section and a subsequent section on a roll-to-roll coated electrode manufacturing line that manufactures a plate electrode. The system also determines a position of the foreign metallic particle on the electrode strip moving on the roll-to-roll coated electrode manufacturing line. The system also triggers, in response to detection of the foreign metallic particle and based on the position of the foreign metallic particle and a speed at which the electrode strip is moving, the second sensor, the second sensor generating a reflectance spectrum of the foreign metallic particle. The system also analyzes the reflectance spectrum to identify a type of metal of which the foreign metallic particle is composed.
Type:
Application
Filed:
September 27, 2023
Publication date:
August 29, 2024
Applicants:
Toyota Research Institute, Inc., Toyota Jidosha Kabushiki Kaisha
Abstract: An artificial intelligence (AI) task control method, a terminal, a base station, and a storage medium are provided. The base station includes a first functional module configured to perform at least one of the following functions by interacting with the terminal: AI task control, AI task execution, network decision generation, and data management for the terminal.
Type:
Application
Filed:
July 5, 2022
Publication date:
August 29, 2024
Applicants:
CHINA MOBILE COMMUNICATION CO., LTD RESEARCH INSTITUTE, CHINA MOBILE COMMUNICATIONS GROUP CO., LTD.
Inventors:
Yingying WANG, Junshuai SUN, Xin SUN, Na LI, Yun ZHAO, Guangyi LIU
Abstract: A ceramic heat storage body includes a shell that contains alumina as a main component and has an average absorbance larger than 0.3 at 1.7 ?m to 2.7 ?m, which is a center wavelength of radiant heat at 800° C. to 1400° C. In addition to alumina, the shell contains oxides containing Cr, Fe, Mn, and Co in an amount of 1 weight % or more in compound equivalent. Furthermore, the shell is a shell that has an outer surface in a shape of a spheroid including a sphere and internally has a hollow portion. Moreover, in the shell, during heat storage, a center temperature of a hollow portion is higher than an inner surface temperature of the shell.
Type:
Application
Filed:
June 24, 2022
Publication date:
August 29, 2024
Applicants:
CHUBU ELECTRIC POWER MIRAIZ CO., INC., CHUBU ELECTRIC POWER CO., INC., NATIONAL UNIVERSITY CORPORATION TOKAI NATIONAL HIGHER EDUCATION AND RESEARCH SYSTEM
Abstract: Here discloses an optical display system and an electronics device. The optical display system comprises: image-generating display; controllable polarization rotator module, which receives light from the image-generating display and outputs the light into polarized light with a first polarization and/or a second polarization under control; a first reflective lens, which reflects the polarized light with a first polarization to a pupil of an observer; and a second reflective lens, which reflects the polarized light with a second polarization to the pupil, wherein the first reflective lens and the second reflective lens have different optical powers to produce image planes at different depths.
Type:
Application
Filed:
June 21, 2022
Publication date:
August 29, 2024
Applicants:
University of Central Florida Research Foundation, Inc., Goertek Inc.
Abstract: Provided herein a polyoxometalate compound represented by formula (I): (Q)n[XMaMbMc(La)(Lb)(Lc)W9O37] (I) or a solvate thereof; and a method of electrocatalytic reduction of carbon dioxide (CO2) using the polyoxometalate compound.
Abstract: It is an object of the present invention to provide a method for determining the medicinal effect or sensitivity of an anti-transferrin receptor antibody. According to the present invention, provided is a method for determining the medicinal effect or sensitivity of an anti-human transferrin receptor antibody having an action to inhibit the binding between human transferrin and a human transferrin receptor, wherein the method uses an intracellular iron content as an indicator.
Type:
Application
Filed:
October 8, 2021
Publication date:
August 29, 2024
Applicants:
National University Corporation Tokai National Higher Education and Research System, PERSEUS PROTEOMICS INC.
Inventors:
Hitoshi KIYOI, Yuichi ISHIKAWA, Marie NAKASHIMA, Yuta OHIRA, Junpei OYA, Fumiko NOMURA, Keiko KATSUMI, Aya SAKAMOTO, Yoshinori UKAI, Tadashi MATSUURA
Abstract: Extended-release pharmaceutical compositions comprising a biodegradable microparticle, nanoparticle or other polymeric formulation of Formula I, Formula IL, or Formula III or a pharmaceutically acceptable salt thereof are provided with advantageous properties for in vivo delivery to a patient in need thereof. The extended-release formulations overcome historic obstacles in cromakalim, including levcromakalim, delivery.
Type:
Application
Filed:
February 12, 2024
Publication date:
August 29, 2024
Applicants:
Qlaris Bio, Inc., Mayo Foundation for Medical Education and Research
Inventors:
Thurein M. Htoo, Barbara M. Wirostko, Michael P. Fautsch
Abstract: A method, a system and a computer program product are provided for applying a neural network including an action sequence decoder for generating an action sequence for a robot to perform a task. The neural network is applied to generate the action sequence based on recordings demonstrating humans performing tasks. In an example, the method comprises collecting a recording and a sequence of captions describing scenes in the recording; extracting feature data from the recording; encoding the extracted feature data to produce a sequence of encoded features; and applying the action sequence decoder to produce a sequence of actions for the robot based on the sequence of encoded features having a semantic meaning corresponding to a semantic meaning of the sequence of captions. The feature data includes features of a video signal, an audio signal, and/or text transcription capturing a performance of the task.
Type:
Application
Filed:
September 27, 2023
Publication date:
August 29, 2024
Applicant:
Mitsubishi Electric Research Laboratories, Inc.
Inventors:
Chiori Hori, Jonathan Le Roux, Devesh Jha, Siddarth Jain, Radu Ioan Corcodel, Diego Romeres, Puyuang Peng, Xinyu Liu, David Harwath
Abstract: The present invention relates to a population of lymphocytes comprising at least 90% CD3+ T cells and less than 5% B cells, wherein at least 70% of said T cell portion are viable, at least 20% are CD27/CD28 double positive and less than 10% are triple positive for CD45RA, CD57 and KLRG1 and a method for expansion of a population of lymphocytes specific for one or more antigens comprising a single culture phase.
Type:
Application
Filed:
April 29, 2022
Publication date:
August 29, 2024
Applicants:
TIGEN PHARMA SA, LUDWIG INSTITUTE FOR CANCER RESEARCH LTD, CENTRE HOSPITALIER UNIVERSITAIRE VAUDOIS (CHUV)
Inventors:
George Coukos, Alexandre Harari, Simone Steiner, Florence Salmon
Abstract: A method for sequential point cloud forecasting is described. The method includes training a vector-quantized conditional variational autoencoder (VQ-CVAE) framework to map an output to a closest vector in a discrete latent space to obtain a future latent space. The method also includes outputting, by a trained VQ-CVAE, a categorical distribution of a probability of V vectors in a discrete latent space in response to an input previously sampled latent space and past point cloud sequences. The method further includes sampling an inferred future latent space from the categorical distribution of the probability of the V vectors in the discrete latent space. The method also includes predicting a future point cloud sequence according to the inferred future latent space and the past point cloud sequences. The method further includes denoising, by a denoising diffusion probabilistic model (DDPM), the predicted future point cloud sequences according to an added noise.
Type:
Application
Filed:
October 10, 2023
Publication date:
August 29, 2024
Applicants:
TOYOTA RESEARCH INSTITUTE, INC., TOYOTA JIDOSHA KABUSHIKI KAISHA, CARNEGIE MELLON UNIVERSITY, THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Inventors:
Junyu NAN, Xinshuo WENG, Jean MERCAT, Blake Warren WULFE, Rowan Thomas MCALLISTER, Adrien David GAIDON, Nicholas Andrew RHINEHART, Kris Makoto KITANI
Abstract: A method of forming a biomass epoxy resin composition includes mixing 100 parts by weight of biomass 2,5-furandicarboxylic acid, 900 to 1100 parts by weight of epihalohydrin, and a catalyst to form a mixture. The method includes heating the mixture to 80° C. to 95° C. to react for 2 to 5 hours to form a ring-opening intermediate product, and adding an alkaline for ring closing the ring-opening intermediate product to form the biomass epoxy resin composition, wherein the catalyst includes 0.8 to 8 parts by weight of triphenyl phosphine and 0.01 to 0.1 parts by weight of 4-methoxyphenol.
Type:
Application
Filed:
January 16, 2024
Publication date:
August 29, 2024
Applicant:
INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
Inventors:
Yi-Syuan WANG, Cheng-Han HSIEH, Chih-Ming HU