Abstract: Various examples are provided for modular prosthetic devices and their use. In one example, a device includes a chassis assembly including a joint portion; and an interchangeable module that can be removably attached to the chassis assembly. The interchangeable modules can be configured for use in a wide variety of applications. The interchangeable modules can be quickly exchanged for different activities.

Abstract: Unique compounds useful for inhibiting a proteasome in a cell, pharmaceutical compositions and methods of their use are provided herein.

Abstract: A novel silver-lithium-iodine solid-state energy device and system are disclosed. The rechargeable, self-assembled, dual-function, metal-iodide battery exhibits small size and high deliverable power. Inert until activation, the device may be stored for long periods of time. Upon activation, the device assembles the required electrochemical moieties for operation without external intervention. The device limits short-circuiting and self-discharge of the system by spontaneous reactions at the electrode/electrolyte interfaces, and thus is self-healing. By incorporating both silver and lithium in the same system, a dual function is achieved, whereby the characteristics of a lithium-based battery dominate at a low load and those of a silver-based battery dominate under a high load.

Abstract: The present invention relates to methods of treatment of a disease or pathology of the central nervous system, an eating disorder, or substance use disorder, drug dependence/abuse and withdrawal therefrom comprising administering at least one N-phenylalkyl amphetamine derivative and pharmaceutical compositions comprising at least one N-phenylalkyl amphetamine derivative to an individual in need thereof.

Abstract: The present disclosure relates to compounds and compositions that inhibit the NLRP3 inflammasome, for example, a compound according to formula I wherein R1 is C1-4 alkyl; and R2 is H or C1-4 alkyl, provided that when R2 is H. R1 is not CH3. Also disclosed are methods for treating multiple sclerosis using the compounds and compositions.

Abstract: Disclosed herein are a method, an apparatus and a storage medium for image encoding/decoding using a segmentation map. A feature vector for an image may be extracted using a segmentation map. The image may be encoded using the segmentation map and the feature vector. An output stream from an encoding apparatus may include a video stream and a feature stream. An input stream to a decoding apparatus may include a video stream and a feature stream. The image may be reconstructed using a reconstructed segmentation map and a reconstructed feature vector.

Abstract: A method and system for leakage status evaluation and leaks location of a solid waste land disposal facility. The method includes: arranging an off-site emitting electrode for the solid waste land disposal facility, and arranging a plurality of intra-site receiving electrodes on a solid waste pile surface in a grid shape; selecting a power supply to collect a current value between the off-site emitting electrode and each of the intra-site receiving electrodes respectively, and determining a maximum current value point Mn of the solid waste pile surface and a maximum current value An; selecting an off-site point So2, and measuring a current value between the off-site emitting electrode and the point So2 as a reference current Ab under the same power supply condition; and determining a leakage status of the solid waste land disposal facility based on a ratio of the maximum current value An to the reference current Ab.

Abstract: A feature point integration positioning system includes a moving object, an image input source, an analyzing module and a positioning module. The image input source is disposed at the moving object to shoot an environment for obtaining a sequential image dataset. The analyzing module includes a machine vision detecting unit configured to generate a plurality of first feature points in each of the images based on each of the images, a deep learning detecting unit configured to generate a plurality of second feature points in each of the images based on each of the images, and an integrating unit configured to integrate the first feature points and the second feature points in each of the images into a plurality of integrated feature points in each of the images. The positioning module confirms a position of the moving object relative to the environment at each of the time points.

Abstract: Disclosed herein is an intra prediction method including: deriving neighbor prediction mode information from a left neighbor prediction mode and an upper neighbor prediction mode; deriving an intra prediction mode for a decoding target unit by using the derived neighbor prediction mode information; and performing intra prediction on the decoding target unit based on the intra prediction mode. According to exemplary embodiments of the present invention, image encoding/decoding efficiency can be improved.

Abstract: The present invention provides a method for increasing the sucrose ester content of a tobacco plant or tobacco cell culture, the method comprising modifying said tobacco plant or tobacco cell culture by inhibiting the activity or expression of a diterpene synthesis gene. The present invention also provides for the use of a diterpene synthesis gene for increasing the sucrose ester content of a tobacco plant or tobacco cell culture, as well as tobacco cells, tobacco plants, tobacco plant propagation materials, harvested leaves, processed tobaccos, or tobacco products obtainable in accordance with the invention.

Abstract: Disclosed herein are methods for the production of Cannabis meristem explants from dry seeds. Also described are methods of transforming and gene editing using the Cannabis meristem explants disclosed herein.

Abstract: Binding of the transcriptional co-activator, YAP1, to the transcription factor Oct4, induces Sox2, which is a transcription actor necessary for the self-renewal of stem-like cells from non-small cell lung cancer. The WW domain of YAP1 binds to the PPxY motif of Oct4 to induce Sox2. Delivering a peptide corresponding to the WW domain could prevent the induction of Sox2 and sternness. Similarly, peptides and mimetics of the PPxY motif would be able to inhibit sternness. Disclosed are compounds that affect the Yap1:Oct4 interaction.

Abstract: Disclosed are methods and apparatuses for supporting BWP-based operations in sidelink communication. An operation method of a first terminal in a communication system may include receiving, from a base station, configuration information of a mapping relationship between an uplink (UL) bandwidth part (BWP) and a sidelink (SL) BWP; when a UL switching operation for the UL BWP is performed, performing an SL switching operation for the SL BWP mapped to the UL BWP based on the mapping relationship without separate signaling indicating execution of the SL switching operation; and performing sidelink communication with a second terminal in a switched SL BWP.

Abstract: A maize pollen composition containing polyether ether ketone and pollen for collecting pollen and storing pollen.

Abstract: An air parking brake electric control valve includes an air valve unit and a self-lock unit. The air valve unit includes a main valve body, an auxiliary valve body, a valve core and a first electromagnetic assembly. The valve core is driven by the first electromagnetic assembly to move between a first action position and a second action position. The self-lock unit is disposed on the auxiliary valve body, and includes a second electromagnetic assembly. The second electromagnetic assembly includes a movable column operable to move between a release position and a lock position.

Abstract: A substrate processing system includes a first chamber including a substrate support. A showerhead is arranged above the first chamber and is configured to filter ions and deliver radicals from a plasma source to the first chamber. The showerhead includes a heat transfer fluid plenum, a secondary gas plenum including an inlet to receive secondary gas and a plurality of secondary gas injectors to inject the secondary gas into the first chamber, and a plurality of through holes passing through the showerhead. The through holes are not in fluid communication with the heat transfer fluid plenum or the secondary gas plenum.

Abstract: A bone screw may be insertable into a bone. The bone screw may have a distal member with bone-engaging threads, a proximal member configured to slidably engage the distal member, and a tension member with a proximal end coupled to the proximal member, and a distal end coupled to the distal member such that, in response to motion of the distal member away from the proximal member, the tension member elongates and urges the distal member to move toward the proximal member. The tension member may be configured such that, at a minimum length of the bone screw, the tension member is pre-stretched so that the tension member is under tension to urge the bone screw to shorten. The bone screw may be inserted in the pre-stretched state. A pre-stretch driver may be used to tension the bone screw prior to or during insertion.

Abstract: The present invention relates to image processing, and more particularly, to a video coding/decoding method using a clipped motion vector and an apparatus thereof. An embodiment of the present invention relates to a method of decoding an image. The method includes clipping a motion vector of a reference picture in a predetermined dynamic range to generate a clipped motion vector, storing the clipped motion vector in a buffer, deriving a motion vector of a coding treeblock using the motion vector stored in the buffer, and performing inter prediction decoding process using the motion vector of the coding treeblock. According to the exemplary embodiment of the present invention, a size of a memory required for storing motion vectors may be reduced.

Abstract: Systems and methods for maintaining an electronic health records system, including a server storing a medical records database. Requests for medical data for a patient in a master problem list are received from a user device, and appropriate list permissions are determined and granted for hierarchical derivative problem lists. Annotated data is received at the server from a user device based on annotations made to a derivative problem list, and problem lists are updated with the received annotated data in real time. The received annotated data is compared with current entries using natural language processing to detect duplicate entries, the duplicate entries are iteratively detected and removed from the master problem list, and non-duplicate entries are stored in authorized derivative problem lists based on the natural language processing and list update permissions for each of the derivative problem lists.

Abstract: In one aspect, the disclosure relates to drug delivery devices for the ionophoretic delivery of a therapeutic agent(s) to the eye. In some aspects, the disclosed ionophoretic ocular delivery device is configured for delivery of a therapeutic agent to the anterior portion of the eye. In various aspects, the present disclosure provides methods for treatment of an ophthalmological disorder, disease, or clinical condition by delivering a therapeutic agent(s) to the eye using a disclosed ionophoretic ocular delivery device. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.