Abstract: A pressure sensor device includes a base layer, a deformable layer bonded to the base layer such that the base layer and the deformable layer define at least one inflatable chamber, and at least one pressure sensor fluidly coupled to the at least one inflatable chamber and operable to produce a signal indicative of a pressure within the at least one inflatable chamber.
Type:
Grant
Filed:
May 31, 2022
Date of Patent:
August 27, 2024
Assignees:
TOYOTA RESEARCH INSTITUTE, INC., TOYOTA JIDOSHA KABUSHIKI KAISHA
Inventors:
Alexander Alspach, Andrew M. Beaulieu, Aimee S. Goncalves
Abstract: The present invention relates to a novel antibody library and an antibody-screening method using same. Having a human sequence-derived specific VH or VL scaffold, the antibody library according to the present invention exhibits high thermodynamic stability and enjoys the advantages of allowing high soluble expression as well as reversible folding. In addition, the antibody according to the present invention includes a variety of rationally controlled CDRs so as to exhibit high specificity and high affinity to all antigens and thus can be advantageously used for selecting an adequate candidate antibody against a target antigen.
Type:
Grant
Filed:
May 31, 2019
Date of Patent:
August 27, 2024
Assignee:
MOGAM INSTITUTE FOR BIOMEDICAL RESEARCH
Inventors:
Dong-Sik Kim, Mi Jung Lee, Mi Young Oh, Hye-Ji Choi, Gil-Jung Kim, Shin A Jang, Ae Rin Yoon
Abstract: Disclosed herein is a method of decoding an image. The method includes acquiring intra chroma prediction information of a current block from a bitstream, deriving an intra chroma prediction mode of the current block based on the intra chroma prediction information, and performing intra prediction with respect to the current block based on the intra chroma prediction mode. The intra chroma prediction mode may be any one of a linear model (LM)) mode, a derived luma (DM) mode, a Planar mode, a Vertical mode, a Horizontal mode and a DC mode, and a first bit of the intra chroma prediction information may be used to determine whether the intra chroma prediction mode is an LM mode.
Type:
Grant
Filed:
December 27, 2019
Date of Patent:
August 27, 2024
Assignees:
Electronics and Telecommunications Research Institute, RESEARCH & BUSINESS FOUNDATION SUNGKYUNKWAN UNIVERSITY
Inventors:
Jung Won Kang, Ha Hyun Lee, Sung Chang Lim, Jin Ho Lee, Hui Yong Kim, Byeung Woo Jeon, Jee Yoon Park
Abstract: Compositions and methods for systemic delivery of at least one cargo in a vascular plant. Compositions may include at least one cargo delivery particle, having a core and a shell; and at least one cargo disposed on the shell. The core may include at least one micronutrient. The shell may include a coating material. The at least one cargo delivery particle may have a size of less than about 10 nanometers. Methods may include administering an effective amount of the compositions to a plant.
Type:
Grant
Filed:
September 17, 2020
Date of Patent:
August 27, 2024
Assignee:
UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC.
Abstract: Disclosed herein are novel compositions and methods for stimulation of and the production or expansion of natural killer (NK) cells. Numbers of NK cells can be increased following contact with exosomes modified with one or more stimulatory peptides. Methods and compositions for the production of exosomes, wherein the exosomes comprises stimulatory peptides are also described. Also described are methods of treating cancer using the disclosed NK-stimulating exosomes or NK cells stimulated by the disclosed methods.
Type:
Grant
Filed:
January 26, 2022
Date of Patent:
August 27, 2024
Assignee:
University of Central Florida Research Foundation, Inc.
Inventors:
Alicja J. Copik, Jeremiah L. Oyer, Robert Y. Igarashi, Deborah Altomare
Abstract: A magnetic particle imaging system that includes a magnetic field generating system with at least one magnet and providing a gradient magnetic field within an observation region such that the gradient magnetic field has a dynamic field-free region (FFR) for an object under observation having strongly-interacting magnetic particles distributed therein. The magnetic field generating system also includes a drive field and a slow shift field that dynamically shifts the FFR across a field of view (FOV) within the observation region, where the trajectory of the drive field accommodates for a coercivity of the strongly-interacting magnetic particles by ensuring that the particles in the FOV are saturated to a full coercivity field prior to traversing to an opposite-polarity of coercivity. The magnetic particle imaging system also includes a detection system proximate the observation region and configured to detect a signal from the strongly-interacting magnetic particles.
Type:
Grant
Filed:
July 23, 2020
Date of Patent:
August 27, 2024
Assignees:
The Regents of the University of California, University of Florida Research Foundation, Incorporated
Inventors:
Steven Conolly, Carlos Rinaldi, Bo Zheng, Prashant Chandrasekharan, Daniel Hensley, Shehaab Savliwala, Zhi Wei Tay, Rohan Deepak Dhavalikar
Abstract: A shaft arrangement for a vehicle. The shaft arrangement includes a shaft having a fluid channel extending along an axial direction of the shaft. The shaft includes at least one fluid inlet arranged at an axial distance from a first end of the shaft and extends radially between an outside surface of the shaft and the fluid channel. The shaft arrangement further has a sensor including a first sensor part and a second sensor part, wherein the first sensor part is attached to a first end part of the shaft at the first end of the shaft and the second sensor part is arranged to be attached to a first shaft housing part.
Type:
Grant
Filed:
October 16, 2021
Date of Patent:
August 27, 2024
Assignee:
Ningbo Geely Automobile Research &Dev. Co., Ltd.
Abstract: Systems, kits, and methods for detecting and quantifying proteomic activity using DNA-encoded probes are provided, where the proteomic activity may be enzymatic activity or ligand binding affinity. Such systems and methods encode quantitative proteomic activity information into DNA sequence populations and utilize DNA-linked substrates or ligands as activity probes. The systems, kits, and methods that are directed to detecting ligand affinity further include crosslinking steps to ensure the integrity of the DNA-linked ligands during purification and washing. Signal detection involves the chemical manipulation of a probe population downstream of sample exposure and application of purifying, selective pressure for desired products. Selection-induced changes in DNA abundance between the initial pool and the purified pool indicate sample activity.
Type:
Grant
Filed:
May 18, 2021
Date of Patent:
August 27, 2024
Assignee:
Purdue Research Foundation
Inventors:
Casey J. Krusemark, Kyle Denton, Dongwook Kim, Rachael Jetson
Abstract: A method for a vehicle safety is described. The method includes determining a current steering angle at which a vehicle is traveling. The method also includes displaying the current steering angle relative to a steering angle scale. The method further includes guiding an operator of the vehicle through feedback provided through a steering wheel of the vehicle while displaying the current steering angle relative to the steering angle scale.
Abstract: A deviation measurement device, which is used for measuring the deviation between the center (O) of a substrate (W) and a standard center (O?), and comprises a reference arm (101), a moving arm (103) and a first linear module (102), wherein the moving arm (103) is provided with a first positioning claw (104), and the first positioning claw (104) is used for abutting against two points on an edge of the substrate (W); the reference arm (101) is provided with a second positioning claw (105), and the second positioning claw (105) is used for abutting against two points on the edge of the substrate (W); and the moving arm (103) is arranged opposite the reference arm (101).
Type:
Application
Filed:
May 20, 2022
Publication date:
August 22, 2024
Applicant:
ACM RESEARCH (SHANGHAI), INC.
Inventors:
Hui Wang, Wenbo Liu, Han Han, Shena Jia, Xiaofeng Tao
Abstract: Gene-editing to allow for expression of functional factor VIII for the treatment of hemophilia A is described. The disclosure further provides nanoparticles to deliver gene-editing components to liver sinusoidal endothelial cells (LSEC) to correct mutant factor VIII genes.
Type:
Application
Filed:
May 11, 2022
Publication date:
August 22, 2024
Applicant:
Seattle Children's Hospital d/b/a Seattle Children's Research Institute
Abstract: A method of producing spherical particles is provided herein. Also provided are compositions generated thereby and uses thereof in disease diagnosis and treatment.
Type:
Application
Filed:
June 12, 2022
Publication date:
August 22, 2024
Applicants:
Nano Ghost Ltd, Technion Research & Development Foundation Limited
Inventors:
Osnat BOHANA-KASHTAN, Oded PINKAS, Irina GOTLIV, Haim TSUBERY, Tal Yoetz KOPELMAN, Neta CHAIM, Noa AVNI, Hanna LIANDRES, Roy GOVRIN, Yonatan MALCA, Marcelle MACHLUF, Orit AMSALEM-BERGELSON
Abstract: Lift communications systems, wall-mounted controls, and methods of using and configuring the same are disclosed. A lift communications system includes one or more lifts, each one of the one or more lifts is movable within a space. The lift communications system further includes a wall-mounted control coupled to a wall of the space. The wall-mounted control is configured to communicatively couple to the one or more lifts via a wireless connection. When the wall-mounted control is communicatively coupled to a lift of the one or more lifts, the wall-mounted control is configured to direct operation of the lift and receive data from the lift.
Type:
Application
Filed:
April 30, 2024
Publication date:
August 22, 2024
Applicant:
LIKO RESEARCH & DEVELOPMENT AB
Inventors:
James Ledwith, Melissa R. Stancato, Jesse Newman, Karin Olsson, Daniel Johansson, Sheeza Hussain, Scott M. Corbin, Sravan Mamidi, Todd P. O'Neal, Joseph T. Canter, Jason M. Williams, Gregory J. Shannon, Bryan Weidman
Abstract: A method of a satellite may comprise: transmitting a request signal requesting a terminal to periodically report assistance information for round-trip time calculation; receiving the assistance information periodically reported from the terminal; calculating round-trip times based on the assistance information; and estimating a location of the terminal using the round trip times.
Type:
Application
Filed:
February 16, 2024
Publication date:
August 22, 2024
Applicant:
ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
Abstract: An immuno-oncology therapeutic composition containing, as an active ingredient, an adjuvant including lipopeptides and poly (I:C) provided in one aspect of the present invention can induce a large therapeutic effect on a variety of carcinomas, and can be effectively used for anticancer therapy by significantly enhancing anticancer effects through combined administration with conventional anticancer drugs, such as chemical anticancer drugs, anticancer vaccines, and immune checkpoint inhibitors, having different mechanisms.
Type:
Application
Filed:
May 24, 2022
Publication date:
August 22, 2024
Applicant:
CHA VACCINE RESEARCH INSTITUTE CO., LTD
Inventors:
Jung Sun Yum, Jungki Cho, Byung Cheol Ahn, Sookyung Jeong, Yoonki Heo, Hong Jae Jeon, Chan Kim
Abstract: A gate-all-around field effect transistor with an extended source/drain and a method of manufacturing the same. The gate-all-around field effect transistor has an extended source/drain structure formed by partial etching of channels to solve unbalance between semiconductor devices and enables high speed operation through reduction in RC delay.
Type:
Application
Filed:
September 13, 2023
Publication date:
August 22, 2024
Applicant:
POSTECH Research and Business Development Foundation
Abstract: A high gain patch antenna and a method of manufacturing the same are provided. The antenna includes a substrate with a flat structure including a dielectric, a cross-shaped conductor arranged at a center of an upper part of the substrate, and radiator units arranged in each of four areas divided by the cross-shaped conductor on the upper part of the substrate, wherein each of the radiator units may be arranged to have a 90-degree difference from an adjacent radiator unit with respect to a center of the substrate.
Type:
Application
Filed:
December 11, 2023
Publication date:
August 22, 2024
Applicant:
ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
Inventors:
Seong Mo MOON, Dong Hwan SHIN, Dong Pil CHANG, Han Lim LEE, Woo Hee LIM
Abstract: Disclosed in an embodiment of the present invention is an electroplating device, comprising an electroplating tank, a clamp, a positioning cylinder and an anode, wherein the positioning cylinder is located in the electroplating tank; the positioning cylinder is open at one end; the anode is located inside the positioning cylinder, and the positioning cylinder comes in contact with the anode in a sealing manner; and in the entire surface region of the anode, only a first surface comes in contact with an electroplating solution, and the first surface is parallel and opposite to a substrate, with the center of the first surface being aligned with the center of the substrate, and the size of the first surface being similar to that of an effective electroplating region of the substrate.
Abstract: A semiconductor processing device includes a first chamber; a second chamber movable with respect to first chamber portion between an open position and a closed position, a micro-chamber formed between the first chamber portion and the second chamber portion when the second chamber portion is in the closed position to the first chamber portion. The first chamber portion has a first channel formed on an inner wall surface of the first chamber portion facing the micro-chamber. The second chamber portion has a second channel formed on an inner wall surface of the second chamber portion facing the micro-chamber. When the second chamber portion is in the closed position to the first chamber portion and a semiconductor wafer is accommodated in the micro-chamber, an outer edge surface micro-processing space located outside the semiconductor wafer is formed between the internal surfaces of the first chamber portion and the second chamber portion.
Abstract: A magnetic biomolecule-metal ion self-assembly complex for treatment includes an iron ion; and at least one ligand, wherein the ligand and the iron ion are reversibly self-assembled with each other or self-disassembled from each other, wherein the ligand and the iron ion are self-assembled with each other via a first bond to form a self-assembly, wherein the self-assembling is performed by at least one of the metal ion and the ligand, wherein the self-assembly includes a plural of self-assemblies, wherein the self-assemblies adjacent to each other self-bind to each other via a second bond to form the self-assembly complex. The magnetic biomolecule-metal ion self-assembly complex is effectively used for cancer treatment, osteoarthritis treatment, and bone defect treatment.
Type:
Application
Filed:
January 10, 2024
Publication date:
August 22, 2024
Applicant:
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION