Abstract: Macular degeneration, closed head injury, stroke, irritable bowel disease, and reperfusion injury are all associated with biological injury due to reactive oxygen species, probably due to focal iron overload in many instances. The present invention provides methods and pharmaceutical compositions for treating these diseases and conditions using desferrithiocin analogs of Formula (I). In certain embodiments, the analogs include a poly ether moiety at the 4?-position of the phenyl ring of the compound.
Type:
Grant
Filed:
May 14, 2021
Date of Patent:
March 19, 2024
Assignee:
University of Florida Research Foundation, Incorporated
Abstract: A method for search construct validation is described. The method includes determining a construct of a search query recognized on a search engine of a third party webpage and related constructs represented in a plurality of search results generated based on the search query. The method includes mapping the determined construct to the related constructs represented in the plurality of search results generated based on the search query. The method includes generating a knowledge graph illustrating the mapping between the determined construct and the related constructs and a hierarchy and a strength of a conceptual relationship between the determined construct and the related constructs. The method includes displaying, via an interactive user interface, an interactive graph illustrating the mapping between the determined construct and the plurality of related constructs and the hierarchy and the strength of the conceptual relationship between the determined construct and the plurality of related constructs.
Type:
Grant
Filed:
October 28, 2021
Date of Patent:
March 19, 2024
Assignee:
TOYOTA RESEARCH INSTITUTE, INC.
Inventors:
Shabnam Hakimi, Charlene C. Wu, Matthew Len Lee, Nikos Arechiga
Abstract: Systems and methods are provided for controlling one or more brakes of the vehicle. The system may include a processor and a memory in communication with the processor with a brake control module. The brake control module includes instructions that, when executed by the processor, cause the processor to control the one or more brakes of the vehicle when the vehicle is in a first mode using a brake-by-wire system. When the vehicle is in a second mode, control the brake-by-wire system such that the one or more brakes of the vehicle are controlled using a mechanical braking system and the brake-by-wire system.
Type:
Grant
Filed:
March 26, 2021
Date of Patent:
March 19, 2024
Assignee:
Toyota Research Institute, Inc.
Inventors:
Yan Ming Jonathan Goh, Alexander R. Green, Michael Thompson, Kazunori Nimura
Abstract: A copolymer, a film composition and a composite material employing the same are provided. The copolymer is a copolymerization product of a composition, wherein the composition includes a monomer (a), a monomer (b) and a monomer (c). The monomer (a) is a compound having a structure represented by Formula (I), the monomer (b) is a compound having a structure represented by Formula (II), and the monomer (c) is a compound having a structure represented by Formula (III) wherein R1, R2, R3, R4, R5 and R6 are as defined in specification.
Type:
Grant
Filed:
July 22, 2022
Date of Patent:
March 19, 2024
Assignee:
INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
Abstract: An interworking method between 5G multi-access edge computing (MEC) platforms using a common application programming interface framework (CAPIF) is disclosed. The MEC platform interworking method includes requesting an European telecommunications standards institute (ETSI) MEC to discover a MEC service by an edge enabler server (EES), in response to a request of an edge application server (EAS), obtaining, by the EES, information of a matched MEC service in response to the request of the EAS from the ETSI MEC, and transmitting the information of the matched MEC service by the EES such that the EAS invokes a MEC service provided by the ETSI MEC.
Type:
Grant
Filed:
November 10, 2022
Date of Patent:
March 19, 2024
Assignee:
ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
Abstract: Provided are an actuator, method for manufacturing the actuator, and acoustic transmitter having the actuator. The actuator includes: an elastic metal member having a plurality of curved segments and a plurality of connection segments which constitute a ring structure with a long-axis direction and a short-axis direction; a multilayer piezoelectric member disposed within the ring structure and having a plurality of stacked piezoelectric units along the long-axis direction; and a plurality of coupling members disposed within the ring structure, wherein the multilayer piezoelectric member has two ends in the long-axis direction that are coupled to the connection segments of the elastic metal member in the long-axis direction. A preload stress is imparted to the elastic metal member. A plurality of coupling members having a size corresponding to the preload stress are disposed between the elastic metal member and the multilayer piezoelectric member.
Type:
Grant
Filed:
December 26, 2018
Date of Patent:
March 19, 2024
Assignee:
INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
Abstract: The present disclosure provides methods and systems for the characterization of a potential microtexture region (MTR) of a sample, component, or the like. The methods may include determining a threshold width of spatial correlation coefficient and/or a threshold spatial correlation coefficient slope for an actual MTR, characterizing a potential MTR as an actual MTR or a defect, characterizing an actual MTR as an acceptable MTR or not, and/or characterizing various components with potential MTRs as defective or not. The characterization may include calculating a width of spatial correlation coefficient and/or a spatial correlation coefficient slope of the potential MTR and comparing the width of spatial correlation coefficient to a threshold width of spatial correlation coefficient and/or comparing the spatial correlation coefficient slope to a threshold spatial correlation coefficient slope for the potential MTR to be characterized as an actual MTR or a defect (crack).
Type:
Grant
Filed:
September 2, 2022
Date of Patent:
March 19, 2024
Assignees:
RTX CORPORATION, IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC.
Abstract: The disclosure relates to a fifth generation (5G) or sixth generation (6G) communication system for supporting a higher data transmission rate. An encoding apparatus may obtain state-indicator information indicating a state of each of bits included in the polar code based on an index set of the bits, identify a weak-bit or a second weak-bit corresponding to a parity bit candidate position preset according to an interconnection within a parity-check (PC)-chain of the polar code and between PC-chains of the polar code as a parity bit, based on a number of weak-bits determined according to the state-indicator information and a number of bits to be used as parity bits, and obtain a polar code including the identified parity bit.
Type:
Grant
Filed:
May 20, 2022
Date of Patent:
March 19, 2024
Assignees:
Samsung Electronics Co., Ltd., RESEARCH & BUSINESS FOUNDATION SUNGKYUNKWAN UNIVERSITY
Inventors:
Kwonjong Lee, Seunghyun Lee, Sanghyo Kim, Minyoung Chung, Hyosang Ju, Jisang Park
Abstract: Embodiments of the disclosure relate to an optical fiber cable having at least one optical fiber, a cable jacket, and a foam layer. The cable jacket has an inner surface and an outer surface. The outer surface is an outermost surface of the optical fiber cable, and the inner surface is disposed around the at least one optical fiber. The foam layer is disposed between the at least one optical fiber and the cable jacket. The foam layer includes a polymer component having from 30% to 100% by weight of a polyolefin elastomer (POE) or thermoplastic elastomer (TPE) and from 0% to 70% by weight of low density polyethylene (LDPE). The foam layer has a closed-cell morphology having pores with an average effective circle diameter of 10 ?m to 500 ?m. Further, the expansion ratio of the foam layer is at least 50%.
Type:
Grant
Filed:
October 12, 2021
Date of Patent:
March 19, 2024
Assignee:
CORNING RESEARCH & DEVELOPMENT CORPORATION
Inventors:
Ryan Thomas Adams, Bradley Jerome Blazer, Anne Germaine Bringuier, Xiaole Cheng, Sergey Vladimirovich Chernykh, John Richard Jacks, Rebecca Elizabeth Sistare
Abstract: Provided are a method and apparatus for evaluating a degree of frequency regulation urgency of a generator set, a power system and a storage medium.
Type:
Grant
Filed:
January 17, 2020
Date of Patent:
March 19, 2024
Assignees:
STATE GRID FUJIAN ELECTRIC POWER COMPANY LIMITED, STATE GRID FUJIAN ELECTRIC POWER RESEARCH INSTITUTE, CHINA ELECTRIC POWER RESEARCH INSTITUTE COMPANY LIMITED
Abstract: The present disclosure discloses a servo motor and an encoder calibration method. The encoder calibration method includes: calculating a gain error, an offset error and a phase error, by an error calculation block, according to a first signal and a second signal output by an encoder; calculating at least one gain calibration parameter, at least one offset calibration parameter and at least one phase calibration parameter, by the error calibration block, according to the gain error, the offset error and the phase error; and calibrating sequentially, by the encoder, the gain, the offset and the phase of the first signal and the second signal according to the at least one gain calibration parameter, the at least one offset calibration parameter and the at least one phase calibration parameter, wherein performing at least one gain calibration and offset calibration after the phase calibration is completed.
Type:
Grant
Filed:
April 4, 2022
Date of Patent:
March 19, 2024
Assignee:
INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
Abstract: The present inventions relates to an isolated nucleic acid molecule comprising a nucleotide sequence coding for a depolarizing light-gated ion channel functionally linked to a promoter leading to the specific expression of said depolarizing light-gated ion channel in a retinal photoreceptor, or the nucleotide sequence complementary to said nucleotide sequence, for use in treating or ameliorating blindness. The present invention also relates to methods of using such nucleic acid molecules in the treatment of blindness.
Type:
Grant
Filed:
October 30, 2020
Date of Patent:
March 19, 2024
Assignee:
FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH
Abstract: Systems and methods for cleaning an edge ring pocket are described herein. One of the methods includes providing one or more process gases to a plasma chamber, supplying a low frequency (LF) radio frequency (RF) power to an edge ring that is located adjacent to a chuck of the plasma chamber. The LF RF power is supplied while the one or more process gases are supplied to the plasma chamber to maintain plasma within the plasma chamber. The supply of the LF RF power increases energy of plasma ions near the edge ring pocket to remove residue in the edge ring pocket. The LF RF power is supplied during the time period in which a substrate is not being processed within the plasma chamber.
Type:
Grant
Filed:
July 22, 2020
Date of Patent:
March 19, 2024
Assignee:
Lam Research Corporation
Inventors:
Eric Hudson, Scott Briggs, John Holland, Alexei Marakhtanov, Felix Leib Kozakevich, Kenneth Lucchesi
Abstract: The present disclosure relates to a connector assembly and a corresponding method to reverse polarity of the connector. The method enables polarity reversal without bending/twisting optical fibers within the connector assembly.
Type:
Grant
Filed:
March 2, 2022
Date of Patent:
March 19, 2024
Assignee:
Corning Research & Development Corporation
Abstract: Multi-beamwidth radio frequency (RF) beamforming optimization in a wireless communications apparatus is disclosed. The wireless communications apparatus includes a signal processing circuit configured to process an RF communications signal for radiation in a set of RF beams optimized to maximize coverage in a wireless communications cell. In examples disclosed herein, the set of RF beams includes a center RF beam and a number of edge RF beams. Specifically, the center RF beam is formed with a wider beamwidth to cover a larger center area of the wireless communications cell and, the edge RF beams are each formed with a narrower beamwidth to improve coverage in an edge area of the wireless communications cell. As a result, it may be possible to maximize coverage in the wireless communications cell with fewer RF beams, thus helping to reduce computational complexity, processing latency, and energy consumption of the wireless communications apparatus.
Type:
Grant
Filed:
June 10, 2022
Date of Patent:
March 19, 2024
Assignee:
CORNING RESEARCH & DEVELOPMENT CORPORATION
Inventors:
Shirish Nagaraj, Deepak Pengoria, Jiadong Wang
Abstract: The present disclosure is concerned with 2-pyrimidone compounds that are capable of inhibiting a viral infection and methods of treating alphavirus viral infections such as, for example, chikungunya, Eastern equine encephalitis (EEEV), Western equine encephalitis (WEEV), and Venezuelan equine encephalitis using these compounds. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
Type:
Grant
Filed:
December 13, 2022
Date of Patent:
March 19, 2024
Assignees:
Southern Research Institute, Oregon Health and Science University
Inventors:
Ashish Kumar Pathak, Corinne E. Augelli-Szafran, Atefeh Garzan, Daniel Steblow, Nicole Haese
Abstract: The present disclosure relates to the field of microwave and optoelectronic technologies, and in particular to an integrated microwave photon transceiving front-end for a phased array system, including: a ceramic substrate, on which a control integrated circuit, a silicon-based photonic integrated chip, a first amplifying chipset, a second amplifying chipset, and a microwave switch chipset are carried. The control integrated circuit is configured to control the silicon-based photonic integrated chip and the microwave switch chipset by means of an input control signal. The silicon-based photonic integrated chip is connected at one end with an input/output optical fiber, and at the other end with the first amplifying chipset and the second amplifying chipset. The two amplifying chipsets are connected to the microwave switch chipset respectively, and the microwave switch chipset is further connected with a phased array antenna.
Type:
Grant
Filed:
April 22, 2020
Date of Patent:
March 19, 2024
Assignee:
CHINA ELECTRONICS TECHNOLOGY GROUP CORPORATION NO. 44 RESEARCH INSTITUTE
Abstract: Disclosed is a pulse radar apparatus including a clock generator generating a transmission clock signal, a reception clock signal, and a sensitivity adjustment interval signal, a transmitter radiating a transmission pulse based on the transmission clock signal, and a receiver receiving a first pulse and a second pulse, which are associated with the transmission pulse, with different sensitivities based on the reception clock signal and the sensitivity adjustment interval signal.
Type:
Grant
Filed:
September 22, 2021
Date of Patent:
March 19, 2024
Assignee:
Electronics and Telecommunications Research Institute
Abstract: Methods of culturing T cells are provided. Accordingly there is provided a method of culturing T cells comprising culturing T cells in the presence of a T cell stimulator, an exogenous CCL21 and an exogenous ICAM1, thereby culturing the T cells. Also provided are cell cultures, isolated T cells and uses of same.
Type:
Grant
Filed:
March 2, 2018
Date of Patent:
March 19, 2024
Assignees:
YEDA RESEARCH AND DEVELOPMENT CO. LTD., THE MEDICAL RESEARCH, INFRASTRUCTURE AND HEALTH SERVICES FUND OF THE TEL AVIV MEDICAL CENTER
Abstract: A new and distinct cultivar of Distylium plant named ‘DISmd-15-18’, characterized by its compact, mounding and evergreen growth habit, and its ovate-elliptical shaped leaves, that are dark green once mature and blueish-purple in color when young. The inventor believes it could be used as a foundation plant in the southern United States.
Type:
Grant
Filed:
May 3, 2023
Date of Patent:
March 19, 2024
Assignee:
University of Georgia Research Foundation, Inc.