Patents Assigned to State University
  • Methods for making 1,3-dihydroxyacetone (DHA) from glycerol
    Patent number: 8735633
    Abstract: A method comprising reacting glycerol with acetaldehyde or 1,1-diethoxyethane to produce 1,3-dihydroxyacetone (DHA), without using fermentation or direct oxidation of the glycerol is provided. DHA is useful in various products, including as a sunless tanning agent.
    Type: Grant
    Filed: July 14, 2011
    Date of Patent: May 27, 2014
    Assignee: Board of Trustees of Michigan State University
    Inventors: Dennis Miller, Xi Hong, Carl Lira, Omar McGiveron
  • Systems and methods for harvesting algae from photobioreactors
    Patent number: 8734805
    Abstract: A method for harvesting algae according to embodiments of the present invention includes filling a reservoir at least partially with a liquid, submerging a bag at least partially in the liquid, the bag containing media, the media comprising algae, the bag comprising a first end, a second end, a harvesting port located closer to the first end than to the second end, and a gas port, delivering gas into the bag through the gas port, and raising the second end of the bag by accumulating the gas at the second end to flow the media toward the harvesting port.
    Type: Grant
    Filed: June 23, 2010
    Date of Patent: May 27, 2014
    Assignees: Solix Biosystems, Inc., Colorado State University Research Foundation
    Inventors: Peter F. Hentges, Thomas Carroll Barlow, Jeff Tyler Penoyer, David Scott Gorham, Jason Charles Quinn, Peter Allen Letvin, Christopher Wayne Turner, Guy Robert Babbitt, Nicholas Paul Echter, James William Howland
  • Medthods, devices and formulations for targeted endobronchial therapy
    Patent number: 8733350
    Abstract: The present invention provides an improved means of treating tracheobronchitis, bronchiectasis and pneumonia in the nosocomial patient, preferably with aerosolized anti gram-positive and anti-gram negative antibiotics administered in combination or in seriatim in reliably sufficient amounts for therapeutic effect. In one aspect, the invention assures this result when aerosol is delivered into the ventilator circuit. In one embodiment the result is achieved mechanically. In another embodiment, the result is achieved by aerosol formulation. In another aspect, the invention assures the result when aerosol is delivered directly to the airways distal of the ventilator circuit. The treatment means eliminates the dosage variability that ventilator systems engender when aerosols are introduced via the ventilator circuit.
    Type: Grant
    Filed: August 24, 2009
    Date of Patent: May 27, 2014
    Assignee: The Research Foundation for the State University of New York
    Inventors: Gerald Smaldone, Lucy B. Palmer
  • Parallel approach to XML parsing
    Patent number: 8739022
    Abstract: A language for semi-structured documents, XML has emerged as the core of the web services architecture, and is playing crucial roles in messaging systems, databases, and document processing. However, the processing of XML documents has a reputation for poor performance, and a number of optimizations have been developed to address this performance problem from different perspectives, none of which have been entirely satisfactory. Parallel XML parsing leverages the growing prevalence of multicore architectures in all sectors of the computer market, and yields significant performance improvements. The design consists of an initial preparsing phase to determine the structure of the XML document (or other data document), followed by a full, parallel parse. The results of the preparsing phase are used to help partition the XML document for data parallel processing.
    Type: Grant
    Filed: September 25, 2008
    Date of Patent: May 27, 2014
    Assignee: The Research Foundation for The State University of New York
    Inventors: Kenneth Chiu, Yinfei Pan
  • Controlled polarity group III-nitride films and methods of preparing such films
    Patent number: 8734965
    Abstract: The present invention provides methods of preparing Group III-nitride films of controlled polarity and substrates coated with such controlled polarity films. In particular, the invention provides substrate preparation steps that optimize the substrate surface for facilitating growth of a Group III-polar film, an N-polar film, or a selectively patterned film with both a Group III-polar portion and an N-polar portion in precise positioning. The methods of the invention are particularly suited for use in CVD methods.
    Type: Grant
    Filed: September 30, 2010
    Date of Patent: May 27, 2014
    Assignee: North Carolina State University
    Inventors: Raoul Schlesser, Ramón R. Collazo, Zlatko Sitar
  • Micro-sized microbial fuel cell
    Patent number: 8734968
    Abstract: A microbial fuel cell includes an anode portion having an anode and a cathode portion having a cathode. The anode is configured to support an electrically conductive biofilm matrix. A cation exchange membrane is positioned between the anode and the cathode. The anode portion and the cation exchange membrane define an anode chamber having a volume of between about 1 ?L and about 100 ?L and configured to receive an anolyte. The cathode portion and the cation exchange membrane define a cathode chamber having a volume of between about 1 ?L and about 100 ?L and configured to receive a catholyte. The microbial fuel cell is configured to achieve a Coulombic efficiency of at least 30% and/or a power density of at least of 4.7 ?W/cm2. The microbial fuel cell is a microelectromechanical system and can be fabricated in an automated production process.
    Type: Grant
    Filed: June 3, 2011
    Date of Patent: May 27, 2014
    Assignee: Arizona Board of Regents, a body corporated of the State of Arizona acting for and on behalf of Arizona State University
    Inventors: Junseok Chae, Bruce E. Rittmann, Seokheun Choi, Hyung-Sool Lee
  • Isolation of a virus related to canine parvovirus-2 from a raccoon
    Patent number: 8734808
    Abstract: Vaccines preparations against canine parvovirus are provided. The vaccines include a novel canine parvovirus-2 isolated from a raccoon, and related nucleic acids and proteins.
    Type: Grant
    Filed: October 14, 2010
    Date of Patent: May 27, 2014
    Assignee: The Board of Regents for Oklahoma State University
    Inventor: Sanjay Kapil
  • Film bulk acoustic wave resonator-based ethanol and acetone sensors and methods using the same
    Patent number: 8733149
    Abstract: The present invention relates generally to the detection of alcohol. The present invention relates more particularly to the film bulk acoustic wave resonator-based devices, and their use in the sensing of ethanol and/or acetone. One aspect of the invention is a method for detecting ethanol, acetone or both in a gaseous sample including: providing a film bulk acoustic wave resonator having a zinc oxide piezoelectric layer; exposing the film bulk acoustic wave resonator to the gaseous sample; determining the resonant frequency of the film bulk acoustic wave resonator; and determining the concentration of ethanol, the concentration of acetone, or both in the gaseous sample using the resonant frequency of the film bulk acoustic wave resonator.
    Type: Grant
    Filed: January 20, 2011
    Date of Patent: May 27, 2014
    Assignee: Arizona Board of Regents, a body corporate of the State of Arizona, Acting for and on Behalf of Arizona State University
    Inventors: Hongyu Yu, Xiaotun Qiu
  • Use of methanobactin
    Patent number: 8735538
    Abstract: The invention provides compositions comprising and methods employing methanobactin, as well as methanobactin synthetase sequences.
    Type: Grant
    Filed: December 16, 2010
    Date of Patent: May 27, 2014
    Assignees: Iowa State University Research Foundation, Inc., The Regents of the University of Michigan
    Inventors: Alan Angelo DiSpirito, Dong-Won Choi, Jeremy David Semrau, David Keeney
  • Bandwidth recycling in networks
    Patent number: 8737429
    Abstract: A method for use in a broadband wireless access protocol (such as IEEE 802.16 or Long Term Evolution (LTE)) includes scheduling by a base station a stand-by subscriber station for each subscriber station with uplink (UL) transmission opportunities, transmitting by the base station and over the network, a list of each of the stand-by subscriber stations, determining by the stand-by subscriber stations if there is unused bandwidth reserved for the corresponding subscriber station, communicating to the base station that there is the unused bandwidth, and releasing the unused bandwidth for use by the stand-by subscriber station.
    Type: Grant
    Filed: April 12, 2011
    Date of Patent: May 27, 2014
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: David Haoen Chuck, Jien Morris Chang
  • Enhancement of development of oviparous species by in ovo feeding of enteric modulators
    Patent number: 8734837
    Abstract: The development and growth of oviparous species such as birds is enhanced by in ovo administration of an enteric modulator such as HMB. The enteric modulator is administered into the amnion, where it is then orally ingested by the subject. The enteric modulator enhances the enteric development of the subject prior to hatch, and enhances the growth of the animal before and after hatch.
    Type: Grant
    Filed: June 30, 2003
    Date of Patent: May 27, 2014
    Assignees: North Carolina State University, Yissum Research Development Company of the Hebrew University of Jerusalem
    Inventors: Zehava Uni, Peter R. Ferket
  • Intelligent Wi-Fi Packet Relay Protocol
    Publication number: 20140140265
    Abstract: L2Relay is a novel packet relay protocol for Wi-Fi networks that can improve the performance and extend the range of the network. A device running L2Relay is referred to as a relayer, which overhears the packet transmissions and retransmits a packet on behalf of the Access Point (AP) or the node if no acknowledgement is overheard. L2Relay is ubiquitously compatible with all Wi-Fi devices. L2Relay is designed to be a layer 2 solution that has direct control over many layer 2 functionalities such as carrier sense. Unique problems are solved in the design of L2Relay including link measurement, rate adaptation, and relayer selection. L2Relay was implemented in the OpenFWWF platform and compared against the baseline without a relayer as well as a commercial Wi-Fi range extender. The results show that L2Relay outperforms both compared schemes.
    Type: Application
    Filed: November 20, 2013
    Publication date: May 22, 2014
    Applicant: Florida State University Research Foundation, Inc.
    Inventors: Zhenghao Zhang, Shuaiyuan Zhou
  • DNA REPLICON SYSTEM FOR HIGH-LEVEL RAPID PRODUCTION OF VACCINES AND MONOCLONAL ANTIBODY THERAPEUTICS IN PLANTS
    Publication number: 20140141515
    Abstract: Plant viral vectors have great potential in rapid production of proteins, but no simple Here a geminivirus-based system for high-yield and rapid production of oligomeric protein complexes, including virus-like particle (VLP) vaccines and monoclonal antibodies (mAbs) is described. In particular, a single vector that contains two non-competing replicons for transient expression in Nicotiana benthamiana leaves is described. The correct assembly of these subunit proteins into functional oligomeric structures (VLPs or full-size mAb) is also described. This system advances plant transient expression technology by eliminating the need for non-competing viruses, and thus, enhances the realistic commercial application of this technology for producing multiple-subunit protein complexes.
    Type: Application
    Filed: July 17, 2013
    Publication date: May 22, 2014
    Applicant: Arizona Board of Regents for and on behalf of Arizona State University
    Inventors: Hugh S. Mason, Zhong Huang, Qiang Chen, Charles J. Arntzen, Shuo Yuan, Brooke Hjelm
  • VIRUSES MODIFIED WITH UNNATURAL MOIETIES AND METHODS OF USE THEREOF
    Publication number: 20140140962
    Abstract: The invention provides compositions and methods for making and using modified viruses, including infectious viruses, having an external surface linked to at least one heterologous unnatural moiety that is exemplified by unnatural amino acid and unnatural saccharide. The unnatural moiety that is linked to the invention's modified viruses is optionally further linked to a molecule of interest (such as probe, cytotoxin, therapeutic molecule, antibody, affibody, epitope, etc. The invention's compositions and methods for use in, for example, diagnostic applications and therapeutic applications such as gene therapy, oncolytic therapy, and/or vaccine therapy.
    Type: Application
    Filed: April 26, 2012
    Publication date: May 22, 2014
    Applicant: The Research Foundation of State University of New York
    Inventors: Isaac Sheridan Carrico, Banerjee Partha, Patrick Hearing, Oum Yoon Hyeun
  • CHIMERIC OSPA GENES, PROTEINS AND METHODS OF USE THEREOF
    Publication number: 20140141030
    Abstract: The invention relates to the development of chimeric OspA molecules for use in a new Lyme vaccine. More specifically, the chimeric OspA molecules comprise the proximal portion from one OspA serotype, together with the distal portion from another OspA serotype, while retaining antigenic properties of both of the parent polypeptides. The chimeric OspA molecules are delivered alone or in combination to provide protection against a variety of Borrelia genospecies. The invention also provides methods for administering the chimeric OspA molecules to a subject in the prevention and treatment of Lyme disease or borreliosis.
    Type: Application
    Filed: November 12, 2013
    Publication date: May 22, 2014
    Applicants: BAXTER INTERNATIONAL INC., Brookhaven Science Associates, LLC, Research Foundation of the State University of New York, BAXTER HEALTHCARE SA
    Inventors: Brian A. Crowe, Ian Livey, Maria O'Rourke, Michael Schwendinger, John J. Dunn, Benjamin J. Luft
  • NEOEPITOPE DETECTION OF DISEASE USING PROTEIN ARRAYS
    Publication number: 20140141992
    Abstract: A biosensor for use in detecting the presence of diseases, the biosensor comprising a detector for detecting a presence of at least one marker indicative of a specific disease. A method of determining efficacy of a pharmaceutical for treating a disease or staging disease by administering a pharmaceutical to a sample containing markers for a disease, detecting the amount of at least one marker of the disease in the sample, and analyzing the amount of the marker in the sample, whereby the amount of marker correlates to pharmaceutical efficacy or disease stage. Markers for gynecological disease. An immune-imaging agent comprising labeled antibodies, whereby the labeled antibodies are isolated and reactive to proteins overexpressed in vivo. Informatics software for analyzing the arrays, the software including analyzing means for analyzing the arrays.
    Type: Application
    Filed: November 13, 2013
    Publication date: May 22, 2014
    Applicant: Wayne State University
    Inventors: Michael Tainsky, Sorin Draghici, Madhumita Chatterjee
  • SYSTEMS AND METHODS FOR IMPROVING PROCESSOR EFFICIENCY THROUGH CACHING
    Publication number: 20140143494
    Abstract: Certain embodiments herein relate to using tagless access buffers (TABs) to optimize energy efficiency in various computing systems. Candidate memory references in an L1 data cache may be identified and stored in the TAB. Various techniques may be implemented for identifying the candidate references and allocating the references into the TAB. Groups of memory references may also be allocate to a single TAB entry or may be allocated to an extra TAB entry (such that two lines in the TAB may be used to store L1 data cache lines), for example, when a strided access pattern spans two consecutive L1 data cache lines. Certain other embodiments are related to data filter cache and multi-issue tagless hit instruction cache (TH-IC) techniques.
    Type: Application
    Filed: November 19, 2013
    Publication date: May 22, 2014
    Applicant: Florida State University Research Foundation, Inc.
    Inventors: David Whalley, Hans Magnus Sjalander, Alen Bardizbanyan, Per Larsson-Edefors, Peter Gavin
  • Representing signals for classification
    Patent number: 8731293
    Abstract: The subject matter described in this specification can be embodied in a method that includes partitioning a received signal into a sequence of two or more segments. For a given segment in the sequence, the method includes calculating a set of frequency domain coefficients corresponding to the given segment, and identifying local peaks in the set of frequency domain coefficients by applying a threshold. The method also includes providing a multi-dimensional histogram from a plurality of peaks identified from multiple segments, wherein the multi-dimensional histogram jointly represents frequencies and coefficient values corresponding to each of the plurality of identified peaks.
    Type: Grant
    Filed: April 6, 2012
    Date of Patent: May 20, 2014
    Assignee: The Research Foundation for State University of New York
    Inventors: Adly T. Fam, Aaron J. Roof
  • Method for identifying cells based on DNA replication domain timing profiles
    Patent number: 8728979
    Abstract: Methods for identifying and/or distinguishing a homogeneous population of cells based on their replication domain timing profile using high resolution genomic arrays or sequencing procedures are provided. These methods may be used to compare the replication timing profile for a population of cells to another replication timing profile(s), a replication timing fingerprint, and/or one or more informative segments of a replication timing fingerprint, which may be simultaneously or previously determined and/or contained in a database, to determine whether there is a match between them. Based on such information, the identity of the population of cells may be determined, or the identity of the population of cells may be distinguished from other populations of cells or cell types. Methods for determining a replication timing fingerprint for particular cell types are also provided.
    Type: Grant
    Filed: August 28, 2008
    Date of Patent: May 20, 2014
    Assignee: Florida State University Research Foundation
    Inventors: David M. Gilbert, Tyrone Ryba, Ichiro Hiratani
  • Canine influenza virus and related compositions and methods of use
    Patent number: RE44916
    Abstract: The present invention provides an isolated canine influenza virus of subtype H3N8 comprising an HA having SEQ ID NO: 4 or an amino acid sequence that is greater than 99% identical to SEQ ID NO: 4, with the proviso that the amino acids at positions 94 and 233 are identical to SEQ ID NO: 4; a composition comprising attenuated or inactivated virus; isolated or purified HA, NM, NP, M1, NS1, PA, PB1, and PB2 proteins and fragments thereof and compositions comprising same or nucleic acids, optionally as part of a vector, encoding same; and a method of inducing an immune response to canine influenza virus in an animal comprising administering to the animal an aforementioned composition.
    Type: Grant
    Filed: November 29, 2012
    Date of Patent: May 27, 2014
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Kyoung-Jin Yoon, Vickie Cooper