Abstract: A micropump device including a first wafer and a second wafer attached to the first wafer. The first and second wafers are configured to define a chamber therebetween having a predetermined volume. A third wafer is attached to the second wafer to define an inlet section and an outlet section in fluid communication with the chamber. At least one of the second and third wafers are formed to define a moveable diaphragm configured to change the predetermined volume of the chamber for pumping a fluid between the inlet section and the outlet section.
Abstract: Method for making graphene sheets exfoliated by oxidation from graphite by mixing graphite powder with a solution of concentrated sulfuric acid and nitric acid and subjecting the resultant mixture to microware irradiation until a finely dispersed suspension graphene sheets is formed in the solution. Graphene sheets exfoliated by oxidation from graphite are also disclosed.
Type:
Application
Filed:
February 25, 2013
Publication date:
October 10, 2013
Applicant:
Rutgers, The State University of New Jersey
Inventors:
Huixin He, Pui Lam Chiu, Daniel Dino Thayer Mastrogiovanni, Eric Garfunkel
Abstract: The present disclosure relates generally to carbon to carbon coupling processes, and more specifically, to dimerization or trimerization by electrocatalysis of alkenes and alkynes at room temperature.
Type:
Application
Filed:
April 3, 2013
Publication date:
October 10, 2013
Applicant:
Ball State University Board of Trustees
Abstract: Nanofibers are fabricated by introducing a polymer solution into a dispersion medium and shearing the dispersion medium. Droplets of the polymer solution are spun into elongated fibers that are insoluble in the dispersion medium.
Type:
Grant
Filed:
March 24, 2010
Date of Patent:
October 8, 2013
Assignee:
North Carolina State University
Inventors:
Orlin D. Velev, Stoyan Smoukov, Manuel Marquez
Abstract: Many athletic endeavors require focus on a moving object and subsequent coordination of bodily movement either in response to movement of the object or in an attempt to manipulate the object. Coordinated movement of the head and eyes can be improved through training when errors in gaze/head movement-coordination are identified. There exists a need for systems and methods capable of tracking and coordinating change in position of, for example, the head relative to a participant's gaze, and then to provide feedback on a participant's error in tracking moving objects. Exemplary embodiments of the present invention relate to the technology of gaze tracking and more particularly to the application of gaze tracking technology to aid in the development of head-and-eye-movement coordination.
Abstract: In accordance with the present invention, context-induced wireless network information and content transport systems and methods are provided. In another aspect of the present application, a system includes first and second mobile devices that store respective interest profiles. A further aspect of the present application provides that wireless point-to-point connections are formed when the first and second mobile devices are in close physical proximity to each other. In another aspect, the mobile devices automatically exchange advertising content between each other based on the respective interest profiles over the wireless point-to-point connections. Yet another aspect employs a content distribution device wirelessly transmitting advertising content to one of the first and second mobile devices when the one of the first and second mobile devices is in close physical proximity to the content distribution device. A method of operating such a wireless network is also provided.
Type:
Grant
Filed:
February 24, 2010
Date of Patent:
October 8, 2013
Assignee:
Board of Trustees of Michigan State University
Abstract: A method for treating cancer tumors, particularly ovarian cancer tumors, is described, where fused cyclic pyrimidine having a cancer treating ability is selectively delivered to an FR expressing cancerous tumor.
Type:
Grant
Filed:
July 30, 2012
Date of Patent:
October 8, 2013
Assignees:
Duquesne University of The Holy Ghost, Wayne State University
Abstract: A method of adaptive guiding of a web on a roller is disclosed. The method includes computing an output of a reference model, reading an output of a sensor that indicates a web position, determining a difference between the output of the reference model and the output of the sensor, and updating a set off controller parameters for the roller based on the difference.
Type:
Grant
Filed:
February 11, 2011
Date of Patent:
October 8, 2013
Assignee:
The Board of Regents For Oklahoma State University
Inventors:
Prabhakar Pagilla, Aravind Seshadri, MD M. Haque, Ken Hopcus
Abstract: A computed tomography scanner may include a component mounting assembly, an x-ray tube, a filter assembly, and a detector assembly. The filter assembly filters an x-ray fan or cone beam generated by the x-ray tube such that the x-ray beam comprises a high dose portion and one or more low dose portions. The filter assembly reduces the photon count of the low dose portions. The x-ray tube may be coupled to the component mounting assembly at a first end and the detector assembly coupled at a second end that is opposite from the first end. The component mounting assembly is rotatable about a rotation axis. The detector assembly includes an array of individual detector elements capable of detecting x-ray photons of the x-ray beam. The high dose portion strikes a high resolution region of the detector assembly and the low dose portion strikes a low resolution region of the detector assembly.
Abstract: Embodiments of the present system and method are useful for chemical deposition, particularly continuous deposition of anti-reflective films. Disclosed systems typically comprise a micromixer and a microchannel applicator. A deposition material or materials is applied to a substrate to form a nanostructured, anti-reflective coating. Uniform and highly oriented surface morphologies of films deposited using disclosed embodiments are clearly improved compared to films deposited by a conventional batch process. In some embodiments, a scratch-resistant, anti-reflective coating is applied to a polycarbonate substrate, such as a lens. In certain embodiments, an anti-reflective coating is applied to a surface of a solar catalytic microreactor suitable for performing endothermic reactions, where energy is provided to the reactor by absorption of solar radiation. The composition and morphology of the material deposited on a substrate can be tailored.
Type:
Grant
Filed:
July 22, 2011
Date of Patent:
October 8, 2013
Assignee:
State of Oregon acting by and through the State Board of Higher Education on behalf of Oregon State University
Inventors:
Chih-hung Chang, Seung-Yeol Han, Brian K. Paul
Abstract: Several terpene glycosides (e.g., mogroside V, paenoiflorin, geniposide, rubusoside, rebaudioside A, steviol monoside and stevioside) were discovered to enhance the solubility of a number of pharmaceutically and medicinally important compounds, including but not limited to, paclitaxel, camptothecin, curcumin, tanshinone HA, capsaicin, cyclosporine, erythromycin, nystatin, itraconazole, celecoxib, clofazimine, digoxin, oleandrin, nifedipine, and amiodarone. The use of the diterpene glycoside rubusoside and monoterpene glycoside paenoiflorin increased solubility in all tested compounds. The terpene glycosides are a naturally occurring class of water solubility-enhancing compounds that are non-toxic and that will be useful as new complexing agents or excipients in the pharmaceutical, agricultural (e.g., solubilizing pesticides), cosmetic and food industries.
Type:
Grant
Filed:
June 24, 2010
Date of Patent:
October 8, 2013
Assignee:
Board of Supervisors of Louisiana State University And Agricultural and Mechanical College
Abstract: The present invention provides compositions comprising a ligand-nucleic acid nanostructure that promote tumor cell-specific killing and methods of using the compositions. Specially, the invention provides aptamer-nucleic acid nanostructures for treating tumors in a mammal. The methods of making the compositions are also provided.
Type:
Grant
Filed:
October 7, 2010
Date of Patent:
October 8, 2013
Assignee:
Arizona Board of Regents, a body corporate of the State of Arizona Acting for and on Behalf of Arizona State University
Abstract: A variety of phase-separated biocompatible polymer compositions are described. In preferred embodiments the polymers are bioresorbable and/or biodegradable, and have desirable mechanical properties, such as fracture and/or fatigue toughness, that have previously not been a primary design criteria for such polymers. The polymer compositions are useful in a variety of medical applications, such as in the fabrication of medical devices.
Type:
Grant
Filed:
October 11, 2009
Date of Patent:
October 8, 2013
Assignee:
Rutgers, The State University of New Jersey
Inventors:
Don K. Brandom, Durgadas Bolikal, Lioubov Kabalnova, James E. McGrath, Joachim Kohn
Abstract: A new class of imidazolines as 4-position esters with very potent anti-inflammatory as well as antimicrobial activity is described. The synthesis of these imidazolines includes a multicomponent reaction applicable to a combinatorial synthetic approach. The combination of these two key characteristics provides an effective therapeutic drug in the treatment of septic shock as well as many other inflammatory (arthritis and asthma) and infectious disorders. The use of this novel class of non-steroidal agents as anti-inflammatory agents (for the treatment of asthma, etc.), antibacterial agents, and antiseptic agents is described. The compounds are also useful in the treatment of tumors (such as cancers). The imidazolines are potent inhibitors of the transcription factor NF-?B as well as potent activity against the Gram (+) bacterium. The compositions are also useful for treating autoimmune diseases and for inhibiting rejection of organ and tissue transplants.
Type:
Grant
Filed:
April 3, 2009
Date of Patent:
October 8, 2013
Assignee:
Board of Trustees of Michigan State University
Inventors:
Jetze J. Tepe, Peddibhotla Satyamaheshwar
Abstract: A pharmaceutical composition for stimulating nitric oxide production in mammalian cells, the pharmaceutical composition including at least one compound selected from a group consisting of: 2,3-dihydroxypropyl oleate; bis(m-phenoxyphenyl) ether; 6-acetyl-5,6,6a,7-tetrahydro-4H-dibezo(de,g)quinoline; and (+)-N-(p-(2-methylbutoxy)benzylidene)-4-(2-methylbutyl)aniline.
Type:
Application
Filed:
December 9, 2010
Publication date:
October 3, 2013
Applicant:
The Research Foundation of State University of New York
Inventors:
George B. Stefano, Wei Zhu, Kirk Mantione, Richard M. Kream
Abstract: A method to generate siRNAs in vivo is described, as are constructs and compositions useful in the method. The method does not depend on the use of DNA or synthetic constructs that contain inverted duplications or dual promoters so as to form perfect or largely double-stranded RNA. Rather, the method depends on constructs that yield single-stranded RNA transcripts, and exploits endogenous or in vivo-produced miRNAs or siRNAs to initiate production of siRNAs. The miRNAs or siRNAs guide cleavage of the transcript and set the register for production of siRNAs (usually 21 nucleotides in length) encoded adjacent to the initiation cleavage site within the construct. The method results in specific formation of siRNAs of predictable size and register (phase) relative to the initiation cleavage site. The method can be used to produce specific siRNAs in vivo for inactivation or suppression of one or more target genes or other entities, such as pathogens.
Type:
Application
Filed:
March 14, 2013
Publication date:
October 3, 2013
Applicants:
State University
Inventor:
State of Oregon acting by and through the State Board of Higher Education on behalf of Oregon State University
Abstract: Automated, standardized and accurate extraction of relationships within text. Automatic extraction of such relationships/information allows the information to be stored in structured form so that it can be easily and accurately retrieved when needed. Such information can be used to build online search engines for highly specific and accurate information retrieval. The current invention discloses a novel approach to extract such information from raw text based on natural language processing (NLP) and graph theoretic algorithm. The novel method can be applied, for example, to extract protein-protein relationships in biomedical literature. The method can be easily extended to extract other biological relationships between biological terms such as proteins, genes, pathways, diseases and drugs. The method can also be applied to other information domains to extract other relationships.
Type:
Application
Filed:
April 1, 2013
Publication date:
October 3, 2013
Applicant:
The Florida State University Research Foundation, Inc.
Abstract: Livestock insect-removal systems and methods. According to one embodiment, the system may comprise a structure with a defined path for passage of livestock. The system may comprise a container removably attached to the structure and a vacuum device within the container configured to generate a change in pressure within the container. The system may comprise a first duct to expel air from the container and direct air across the path and displace or dislodge insects. The first duct may further comprise a vent to expel bypass air from the first duct. The system may comprise a second duct, positioned along the path to draw air and dislodged insects into the container.
Type:
Grant
Filed:
November 20, 2012
Date of Patent:
October 1, 2013
Assignees:
Spalding Laboratories, Inc., North Carolina State University
Inventors:
Thomas James Spalding, Zachary Thomas Spalding, Steven Smith Denning
Abstract: The invention relates to fusion constructs, methods of using fusion constructs and methods of treating undesirable or aberrant cell proliferation or hyperproliferative disorders, such as tumors, cancers, neoplasia and malignancies.
Type:
Grant
Filed:
March 5, 2009
Date of Patent:
October 1, 2013
Assignees:
Esperance Pharmaceuticals, Inc., Board of Supervisors of Louisiana State University and Agricultural and Mechanical College