Patents Assigned to State University
  • Patent number: 8604161
    Abstract: Ligands that bind to prion proteins and methods for using the ligands for detecting or removing a prion protein from a sample, such as a biological fluid or an environmental sample. The ligands are capable of binding to one or more forms of prion protein including cellular prion protein (PrPc), infectious prion protein (PrPsc), and recombinant prion protein (PrPr). Prions from various species, including humans and hamsters, are bound by the ligands. Also provided is a method of treating or retarding the development of a prion-associated pathology in a subject.
    Type: Grant
    Filed: February 22, 2008
    Date of Patent: December 10, 2013
    Assignees: Pathogen Removal and Diagnostic Technologies Inc., North Carolina State University
    Inventors: David J. Hammond, Julia T. Lathrop, Larisa Cervenakova, Ruben G. Carbonell
  • Patent number: 8604239
    Abstract: The present invention provides manufacturing of and the use of novel diethylene tricarbamide and its condensation reaction products formed by reacting with formaldehyde as wood composite binder resins and in other applications. These resins have thermosetting capabilities and therefore usefulness as binders for wood and other materials with superior resin properties of low cost, colorlessness, exceptionally good binding, and fast curing characteristics, as well as very low formaldehyde emissions. The synthesized novel starting material for the thermosetting resins of the present invention is diethylene tricarbamide.
    Type: Grant
    Filed: April 27, 2012
    Date of Patent: December 10, 2013
    Assignee: Mississippi State University Research and Technology Corporation
    Inventor: Moon Kim
  • Patent number: 8602026
    Abstract: A device, system, and method for isolating a ventilator from one or more patients in which the delivery conditions of gas delivered to an isolation device from a ventilator may drive the delivery of breathing-gas delivered to one or more patients, the breathing-gas having the same or different delivery conditions. In one embodiment, an isolation device may have a housing and a movable partition. The movable partition may be joined to the housing, The movable partition may have a patient side on a first side of the partition and an actuating side on a second side of the partition. The isolation device may include an inlet pressure regulator on the actuating side and/or an exhaust pressure regulator on the patient side. These regulators may alter the delivery conditions (including, but not limited to, pressure and volume) of breathing-gas delivered to a patient.
    Type: Grant
    Filed: August 22, 2008
    Date of Patent: December 10, 2013
    Assignee: The Research Foundation of State University of New York
    Inventors: Bradley P. Fuhrman, Mark S. Dowhy
  • Publication number: 20130324589
    Abstract: Described herein are methods for diagnosing pancreatic cancer using microRNAs. Also described are methods and compositions for the diagnosis and treatment of solid cancers. Methods of identifying inhibitors of tumorigenesis are also provided.
    Type: Application
    Filed: August 12, 2013
    Publication date: December 5, 2013
    Applicant: The Ohio State University
    Inventors: Carlo M. Croce, George A. Calin, Stefano Volinia
  • Publication number: 20130326258
    Abstract: For predicting timing violations, a prediction module predicts a timing violation for a first instruction in a semiconductor device in response to use by the first instruction of a specified sensitized path. The prediction module further mitigates the predicted timing violation.
    Type: Application
    Filed: December 7, 2012
    Publication date: December 5, 2013
    Applicant: Utah State University
    Inventors: Sanghamitra Roy, Koushik Chakraborty
  • Publication number: 20130324891
    Abstract: Apparatus, systems, and methods for current monitoring in ultrasound powered neurostimulation. The apparatus may include an ultrasound transmitter configured to emit an ultrasound output directed at a piezoelectric device implanted in biological tissue. The apparatus may also include a detector configured to detect an induced current in response to the ultrasound output in the biological tissue. The piezoelectric device may include a piezoelectric material and a diode. The apparatus may include a feedback mechanism to control the amount of induced current in the biological tissue.
    Type: Application
    Filed: August 31, 2011
    Publication date: December 5, 2013
    Applicant: Arizona Board of Regents for and on Behalf of Arizona State University
    Inventor: Bruce C. Towe
  • Publication number: 20130323803
    Abstract: The present invention relates to compositions and methods for stable transformation of green microalgae and for production of transgenic green microalgae and/or cyanobacteria that produce extremophile enzymes as co-products during the growth of the green microalgae and/or cyanobacteria for lipid biofuel production. Thus, the present invention provides nucleic acid constructs and methods of transformation useful in the production of stably transformed green microalgae and/or cyanobacteria expressing extremophile enzymes in combination with lipid production for biofuel.
    Type: Application
    Filed: February 3, 2012
    Publication date: December 5, 2013
    Applicant: North Carolina State University
    Inventors: Amy Michele Grunden, Heike Inge Ada Sederoff
  • Publication number: 20130326736
    Abstract: Methods of inhibiting plant parasitic nematodes, methods of obtaining transgenic plants useful for inhibiting such nematodes, and transgenic plants that are resistant to plant parasitic nematodes through inhibition of plant nematode CLE peptide receptor genes are provided. Methods for expressing genes at plant parasitic nematode feeding sites with plant nematode CLE peptide receptor gene promoters are also provided, along with nematode CLE peptide receptor gene promoters that are useful for expressing genes in nematode feeding sites as well as transgenic plants and nematode resistant transgenic plants comprising the promoters.
    Type: Application
    Filed: July 13, 2011
    Publication date: December 5, 2013
    Applicants: THE CURATORS OF THE UNIVERSITY OF MISSOURI, CORNELL RESEARCH FOUNDATION, INC., The United States of America, as represented by the Secretary of Agriculture, Iowa State University Research Foundation, Inc., University of Georgia Research Foundation, Inc., North Carolina State University
    Inventors: Melissa G. Mitchum, Amy Replogle, Jianying Wang, Xiaohong Wang, Shiyan Chen, Ping Lang, Eric L. Davis, Thomas J. Baum, Richard S. Hussey
  • Publication number: 20130324493
    Abstract: Provided herein are compositions comprising ningnanmycin or a derivative thereof, as well as their use for controlling or combating a fungal infection in a plant or plant part (e.g., a turfgrass).
    Type: Application
    Filed: May 31, 2013
    Publication date: December 5, 2013
    Applicant: North Carolina State University
    Inventors: Bangya Ma, Lane P. Tredway
  • Publication number: 20130323262
    Abstract: Methods and kits for treating inflammatory conditions are described that include modulating kallikrein 6 protease activity.
    Type: Application
    Filed: May 23, 2013
    Publication date: December 5, 2013
    Applicants: Florida State University Research Foundation, Inc., Mayo Foundation for Medical Education and Research
    Inventors: Mayo Foundation for Medical Education and Research, Florida State University Research Foundation, Inc.
  • Patent number: 8601082
    Abstract: A method of detecting a compromised machine on a network. The method receives an email message from a machine on the network and classifies it as either spam or non-spam. A probability ratio is then updated, according to whether the message was spam or non-spam, by applying a sequential probability ratio test. If the probability ratio is greater than or equal to a first threshold, then the machine is compromised. If the probability ratio is less than or equal to a second threshold, then the machine is normal. The operations of receiving a message, classifying the message, updating the probability ratio, and indicating the machine is normal or compromised until the probability ratio is greater than or equal to the first threshold are repeated for a plurality of messages. Such repeated operations are performed on each of the messages one at a time, as each of the messages is received.
    Type: Grant
    Filed: October 1, 2012
    Date of Patent: December 3, 2013
    Assignee: The Florida State University Research Foundation, Inc.
    Inventors: Zhenhai Duan, Peng Chen
  • Patent number: 8600528
    Abstract: The present invention relates to a method and system for providing real-time packet-level quality assurance of digital data that controls an electromechanical device transmitted through a network between a transmitting computer and at least one terminal computer. Specifically, all data packets transmitted between the transmitting computer and the at least one terminal computer are passively monitored, and those data packets containing digitized data that controls an electromechanical device of a pre-determined format are selectively recorded to a database. The selectively recorded data packets are then analyzed for determining whether a current set of digitized data that controls an electromechanical device transmitted between the transmitting computer and the at least one terminal computer during a current session would lead to a harmful or undesirable outcome by the electromechanical device being controlled.
    Type: Grant
    Filed: September 18, 2007
    Date of Patent: December 3, 2013
    Assignee: The Research Foundation of State University of New York
    Inventor: Daniel Young-joon Kim
  • Patent number: 8595923
    Abstract: There are provided methods for creating energy conversion devices based on the giant flexoelectric effect in non-calamitic liquid crystals. By preparing a substance comprising at least one type of non-calamitic liquid crystal molecules and stabilizing the substance to form a mechanically flexible material, flexible conductive electrodes may be applied to the material to create an electro-mechanical energy conversion device which relies on the giant flexoelectric effect to produce electrical and/or mechanical energy that is usable in such applications as, for example, power sources, energy dissipation, sensors/transducers, and actuators.
    Type: Grant
    Filed: March 19, 2010
    Date of Patent: December 3, 2013
    Assignee: Kent State University
    Inventors: Antal I. Jakli, John Ernest Harden, Jr., Samuel Sprunt, James T. Gleeson, Peter Palffy-Muhoray
  • Patent number: 8601417
    Abstract: Systems and methods for identifying a Boolean function as either a threshold function or a non-threshold function are disclosed. In one embodiment, in order to identify a Boolean function as either a threshold function or a non-threshold function, a determination is first made as to whether the Boolean function satisfies one or more predefined conditions for being a threshold function, where the one or more predefined conditions include a condition that both a positive cofactor and a negative cofactor of the Boolean function are threshold functions. If the one or more predefined conditions are satisfied, a determination is made as to whether weights for the positive and negative cofactors are equal. If the weights for the cofactors are equal, then the Boolean function is determined to be a threshold function. Further, in one embodiment, this threshold function identification process is utilized in a threshold circuit synthesis process.
    Type: Grant
    Filed: April 20, 2011
    Date of Patent: December 3, 2013
    Assignee: Arizona Board of Regents for and on behalf of Arizona State University
    Inventors: Tejaswi Gowda, Sarma Vrudhula
  • Patent number: 8598118
    Abstract: Small molecule, peptidic hepatocyte growth factors mimics, which act as both mimetics and antagonists, have been generated. These molecules have been shown or predicted to have therapeutic potential for numerous pathologies including dementia, neurodegenerative disease, diabetes and metabolic syndrome, cancer, and defective wound healing.
    Type: Grant
    Filed: February 15, 2013
    Date of Patent: December 3, 2013
    Assignee: Washington State University
    Inventors: Joseph W. Harding, John W. Wright, Caroline C. Benoist, Leen H. Kawas, Gary A. Wayman
  • Patent number: 8600125
    Abstract: In the present methods, the automatic detection of polyps is converted into a 2D pattern recognition problem using conformal mapping and direct volume rendering. The colon surface is first segmented and extracted from the CT data set of the abdomen, which is then mapped to a 2D plane using conformal mapping. Ray casting is used to determine sub-surface density values and the flattened image is rendered using a volume rendering technique with a translucent electronic biopsy transfer function. Polyp candidates are detected by a clustering method which identifies regions of elevated sub-surface density. The potential for false positives is reduced by analyzing the volumetric shape and texture features of the polyp candidate regions.
    Type: Grant
    Filed: June 21, 2006
    Date of Patent: December 3, 2013
    Assignee: The Research Foundation of State University of New York
    Inventors: Arie E. Kaufman, Wei Hong, Xianfeng Gu, Feng Qiu
  • Patent number: 8601081
    Abstract: A method of detecting a compromised machine on a network. The method receives an email message from a machine on the network and classifies it as either spam or non-spam. A probability ratio is then updated, according to whether the message was spam or non-spam, by applying a sequential probability ratio test. If the probability ratio is greater than or equal to a first threshold, then the machine is compromised. If the probability ratio is less than or equal to a second threshold, then the machine is normal. The operations of receiving a message, classifying the message, updating the probability ratio, and indicating the machine is normal or compromised until the probability ratio is greater than or equal to the first threshold are repeated for a plurality of messages. Such repeated operations are performed on each of the messages one at a time, as each of the messages is received.
    Type: Grant
    Filed: October 1, 2012
    Date of Patent: December 3, 2013
    Assignee: The Florida State University Research Foundation, Inc.
    Inventors: Zhenhai Duan, Peng Chen
  • Patent number: 8598080
    Abstract: A novel rice cultivar, designated ‘CL131,’ is disclosed. The invention relates to the seeds of rice cultivar ‘CL131,’ to the plants of rice ‘CL131,’ and to methods for producing a rice plant produced by crossing the cultivar ‘CL131’ with itself or another rice variety, and to single gene conversions of such plants. The invention further relates to hybrid rice seeds and plants produced by crossing the cultivar ‘CL131’ with another rice cultivar. The invention further relates to other derivatives of the cultivar ‘CL131.
    Type: Grant
    Filed: August 25, 2010
    Date of Patent: December 3, 2013
    Assignee: Board of Supervisors of Louisiana State University And Agricultural and Mechanical College
    Inventor: Steven D. Linscombe
  • Patent number: PP24052
    Abstract: A new and distinctly salt and boron tolerant cultivar of prickly pear (Opuntia ficus-indica), named ‘Seleno-Red,’ is particularly distinguishable by its ability to tolerate and grow in high concentration of salt, boron and selenium-laden soil. The cultigen was originally discovered by stringent selection of randomly harvested cladodes (modified stems) and potentially from isolation of a single unique cladode or sport that exhibited high levels of salt and boron tolerance necessary for survival, and then propagated into the ‘Seleno-Red’ cultivar. The cladodes were originally randomly harvested from different individual plants and screened from within a naturally segregating wild population or accession. The ‘Seleno-Red’ cultivar has orange-red flowers, mature green cladodes without glochids, and red-purple fruit.
    Type: Grant
    Filed: March 21, 2012
    Date of Patent: December 3, 2013
    Assignees: California State University, Fresno, Red Rock Ranch, LLC, USDA
    Inventors: Gary Banuelos, John Leonard Freeman, John Diener
  • Patent number: PP24054
    Abstract: A new and distinctive variety of a Malus domestica apple tree, named ‘WA 5’, that is distinguished by its attractive color of bright orange-red with distinct stripe over yellow background and exceptional eating quality, both fresh and after several months in common storage. WA 5 is homozygous for the ethylene production genes ASC1-2/2 and ACO1-1/1 which confer low ethylene production.
    Type: Grant
    Filed: September 24, 2010
    Date of Patent: December 3, 2013
    Assignee: Washington State University Research Foundation
    Inventor: Bruce H. Barritt