Patents Assigned to State University
  • FREQUENCY-CONTROLLED ELECTRO-OPTICAL DEVICE
    Publication number: 20160363799
    Abstract: A frequency controlled electro-optical device includes a substrate having transparent conductive control sections patterned thereon to selectively control the optical state of an electro-optical layer. Each of the control sections are partially electrically isolated from each other by crack lines, which allows for electrical communication between adjacent/proximate control sections to occur. As such, an electrical control signal applied directly to one control section forms an electric field in that control section, and also induces an electrical field in adjacent control sections that are not in direct receipt of the control signal. Therefore, the number of electrical connections required for coupling to a driving circuit to operate the device is minimized, thereby allowing the device to be fabricated with reduced complexity and cost.
    Type: Application
    Filed: June 13, 2016
    Publication date: December 15, 2016
    Applicant: Kent State University
    Inventors: John Lawton West, Da-Wei Lee, Merrill Groom
  • FAST DATA RACE DETECTION FOR MULTICORE SYSTEMS
    Publication number: 20160364315
    Abstract: A system and method to parallelize data race detection in multicore machines are disclosed. The system and method does not generally require any change in the underlining system and the same race detection algorithm may be used, such as FastTrack. In general, race detection is separated from application threads to perform data race analysis in worker threads without inter-thread dependencies.
    Type: Application
    Filed: June 13, 2016
    Publication date: December 15, 2016
    Applicant: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY
    Inventors: Yann-Hang Lee, Young Wn Song
  • SYNTHETIC PEPTIDE FOR REPRESSING TRANSCRIPTION AND/OR GENE EXPRESSION FROM A BINDING SITE OF INTEREST
    Publication number: 20160362452
    Abstract: A synthetic peptide includes an amino acid sequence that: has 70-75%, 75-80%, 80-85%, 85-90%, 90-95% or 95-100% homology with an RpoN box of Region III of an RpoN protein; and binds specifically to a ?24, ?12, or ?24/?12 site(s) of an RpoN promoter. The synthetic peptide is effective for repressing transcription and/or gene expression from a binding site of interest, and the binding site of interest is an RpoN binding site or a cryptic promoter upstream of an RpoN binding site.
    Type: Application
    Filed: June 7, 2016
    Publication date: December 15, 2016
    Applicant: THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK
    Inventors: Christopher T. NOMURA, Benjamin R. LUNDGREN
  • METHOD OF TREATING HYPERGLYCEMIA AND DIABETES AND OF INCREASING ADSORPTION AND EFFICACY OF VITAMIN D
    Publication number: 20160361326
    Abstract: A pharmaceutical for and a method of treating one of vitamin D deficiency, diabetes and pre-diabetes in an animal comprising the steps A method of treating one of vitamin D deficiency, diabetes and pre-diabetes in an animal comprising the steps of administering a first therapeutic agent and a second therapeutic agent to the animal; providing the first therapeutic agent is one of vitamin D, a pharmaceutically acceptable salt, solvate, clathrate, stereoisomer, enantiomer or prodrug thereof, and a pharmaceutically acceptable derivative thereof; and providing the second therapeutic agent is one of L-cysteine, glutathione; glycine, glutamate, and glutathione, or a pharmaceutically acceptable salt, solvate, clathrate, stereoisomer, enantiomer or prodrug thereof, pharmaceutically acceptable derivative thereof, or some combination of thereof.
    Type: Application
    Filed: June 10, 2016
    Publication date: December 15, 2016
    Applicant: Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
    Inventor: Sushil Kumar JAIN
  • Contact-free photomixing probe for device and integrated circuit measurement or characterization
    Patent number: 9518938
    Abstract: A device for measuring and characterizing solid-state devices or integrated circuits at RF frequencies up to 1.0 THz and beyond is provided that includes a transmitting photomixing probe structure and a receiving photomixing probe structure. The transmitting photomixing probe structure and the receiving photomixing probe structure are ac-coupled to the solid-state device or integrated circuit in a contact-free manner.
    Type: Grant
    Filed: January 29, 2013
    Date of Patent: December 13, 2016
    Assignee: WRIGHT STATE UNIVERSITY
    Inventor: Elliott R. Brown
  • Compositions and methods for identifying enzyme and transport protein inhibitors
    Patent number: 9518254
    Abstract: The invention is directed to compositions to screen for small molecule drugs that inhibit proteases, such as viral proteases, e.g., HIV proteases; and methods for making and using these compositions. The invention provides compositions and methods for identifying compositions, e.g., drug molecules, that can inhibit proteases, e.g., HIV proteases. In alternative embodiments, the invention provides cell-based assays to screen for compositions, e.g., small molecules or drugs, that inhibit or modify the activity of enzymes such as calcium-dependent protein convertases involved in HIV envelop protein processing, including cleavage of the HIV gp160 envelope precursor, resulting in gp120 and gp41 envelope products.
    Type: Grant
    Filed: May 3, 2010
    Date of Patent: December 13, 2016
    Assignee: San Diego State University Research Foundation
    Inventor: Roland Wolkowicz
  • Antibacterial agents: phloroglucinol derivatives
    Patent number: 9517994
    Abstract: The invention provides a compound of formula I: or a salt thereof, wherein R1-R3 have any of the values described in the specification, as well as compositions comprising a compound of formula I. The compounds are useful as antibacterial agents.
    Type: Grant
    Filed: January 7, 2013
    Date of Patent: December 13, 2016
    Assignee: Rutgers, The State University of New Jersey
    Inventors: Richard H. Ebright, Juan Shen
  • Single phase lead-free cubic pyrochlore bismuth zinc niobate-based dielectric materials and processes for manufacture
    Patent number: 9520207
    Abstract: Both single phase lead-free cubic pyrochlore bismuth zinc niobate (BZN)-based dielectric materials with a chemical composition of Bi1.5Zn(0.5+y)Nb(1.5?x)Ta(x)O(6.5+y), with 0?x<0.23 and 0?y<0.9 and films with these average compositions with Bi2O3 particles in an amorphous matrix and a process of manufacture thereof. The crystalline BZNT-based dielectric material has a relative permittivity of at least 120, a maximum applied electric field of at least 4.0 MV/cm at 10 kHz, a maximum energy storage at 25° C. and 10 kHz of at least 50 J/cm3 and a maximum energy storage at 200° C. and 10 kHz of at least 22 J/cm3. The process is a wet chemical process that produces thin films of Bi1.5Zn(0.5+y)Nb(1.5?x)Ta(x)O(6.5+y) without the use of 2-methoxyethanol and pyridine.
    Type: Grant
    Filed: May 11, 2015
    Date of Patent: December 13, 2016
    Assignees: The Penn State University, National Science Foundation
    Inventors: Elizabeth K. Michael, Susan Trolier-McKinstry
  • Electrochemical synthesis of chloro-chitosan
    Patent number: 9518077
    Abstract: The present disclosure provides methods for producing chitosan derivatives and the derivatives formed by these methods. The processes of the present disclosure utilize electrochemical methods to functionalize and/or modify amine and/or hydroxyl groups present on chitosan, to form new derivatives. In embodiments, a chloro-chitosan derivative may be prepared. The altered cationic affinity of these derivatives make them excellent candidates for biomedical applications, including pharmaceuticals, as well as food applications.
    Type: Grant
    Filed: February 1, 2013
    Date of Patent: December 13, 2016
    Assignee: The Research Foundation for the State University of New York
    Inventors: Gary P. Halada, Prashant Kumar Jha
  • Ammunition and weapon type identification based on spectroscopic gunshot residue analysis
    Patent number: 9518808
    Abstract: The present invention relates to a method of identifying ammunition type and/or weapon type used to fire the ammunition from gunshot residue. This method involves providing a sample including a gunshot residue, subjecting the sample to spectroscopic analysis to produce a spectroscopic signature for the sample, and identifying the spectroscopic signature to ascertain the type of ammunition and/or the type of weapon used to fire the ammunition. A method of establishing reference spectroscopic signatures for ammunition type and/or weapon type used to fire the ammunition is also disclosed.
    Type: Grant
    Filed: February 16, 2011
    Date of Patent: December 13, 2016
    Assignee: Research Foundation of State University of New York
    Inventors: Igor K. Lednev, Justin Bueno
  • Synthetic fuels and chemicals production with in-situ COcapture
    Patent number: 9518236
    Abstract: Novel redox based systems for fuel and chemical production with in-situ CO2 capture are provided. A redox system using one or more chemical intermediates is utilized in conjunction with liquid fuel generation via indirect Fischer-Tropsch synthesis, direct hydrogenation, or pyrolysis. The redox system is used to generate a hydrogen rich stream and/or CO2 and/or heat for liquid fuel and chemical production. A portion of the byproduct fuels and/or steam from liquid fuel and chemical synthesis is used as part of the feedstock for the redox system.
    Type: Grant
    Filed: September 8, 2010
    Date of Patent: December 13, 2016
    Assignee: THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION
    Inventors: Liang-Shih Fan, Fanxing Li, Liang Zeng
  • Nanocarrier and nanogel compositions
    Patent number: 9517201
    Abstract: Novel classes of multi-arm polyalkylene oxide-based materials including PEG nanocarriers, nanogel particles, and aggregated nanogel particles are disclosed. These classes of compositions may be associated with therapeutic agents and targeting moieties, or visibility enhancing agents, and may have a modified surface structure. In some embodiments the PEG-based materials can be made to provide relatively high drug loads with improved solubility and targeted delivery.
    Type: Grant
    Filed: April 6, 2009
    Date of Patent: December 13, 2016
    Assignee: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Patrick J. Sinko, Stanley Stein, Hilliard Kutscher, Manjeet Deshmukh, Anupa Menjoge, Yashveer Singh, Simi Gunaseelan
  • Apparatus and process for preparing reactive lignin with high yield from plant biomass for production of fuels and chemicals
    Patent number: 9518076
    Abstract: Provided are methods for aqueous isolation of depolymerized lignin in high yield from a lignin-containing biomass composition, comprising positioning a lignin-containing biomass composition into a flowthrough thermal reactor chamber to provide for passage of an aqueous fluid therethrough, contacting the lignin biomass composition with the aqueous fluid under elevated temperature conditions sufficient to provide for lignin release and depolymerization, flowing the aqueous fluid through the reactor chamber under the elevated temperature conditions, to provide an output aqueous fluid comprising released depolymerized lignin, and collecting the depolymerized lignin.
    Type: Grant
    Filed: April 30, 2013
    Date of Patent: December 13, 2016
    Assignee: Washington State University
    Inventors: Bin Yang, Dhrubojyoti Dey Laskar
  • Method for small-signal stability assessment of power systems using shunt current injection source side and series voltage injection load side perturbations
    Patent number: 9519032
    Abstract: A novel method for real-time small-signal stability analysis for power electronic-based components in a power system. The method may be used to monitor a power system in real-time by perturbing the source side of an electronic-based component of the power system of about 0.5 to 1 percent of a nominal current of the power system at the source side using shunt current injection, and perturbing the load side of the power electronic-based component by varying the voltage at the load side using series voltage injection. Time-domain results of the perturbations may be transferred to frequency-domain results and the stability of the power system may be monitored by obtaining a Nyquist contour and employing unit circuit criterion or Generalized Nyquist Criterion.
    Type: Grant
    Filed: April 18, 2016
    Date of Patent: December 13, 2016
    Assignee: The Florida State University Research Foundation, Inc.
    Inventors: Mohamadamin Salmani, Chris S. Edrington
  • Apparatus and method for nanocomposite sensors
    Patent number: 9518878
    Abstract: A sensing material for use in a sensor is disclosed. Such a sensing material includes a polymer base and a piezoresistive nanocomposite embedded into the polymer base in a continuous pattern. The nanocomposite comprises a polymer matrix and a plurality of conductive nanofillers suspended in the matrix. The conductive nanofillers may be one or a combination of nanotubes, nanowires, particles and flakes. The density of the plurality of nanofillers is such that the nanocomposite exhibits conductivity suitable for electronic and sensor applications.
    Type: Grant
    Filed: June 26, 2015
    Date of Patent: December 13, 2016
    Assignee: BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE
    Inventors: Jin-Woo Choi, Chao-Xuan Liu
  • Polypeptides derived from calcitonin receptors and methods of use
    Patent number: 9518105
    Abstract: The present invention is based, in part, on our discovery of compositions and methods that can be used to treat a patient who has a compromised bone (due, for example, to a disease such as osteoporosis or an injury such as a bone fracture). The compositions can also be administered prophylactically. For example, they can be administered to help maintain bone health as a patient ages. More specifically, the compositions include polypeptides that constitute (or that include) a fragment of a calcitonin receptor (CR) and polypeptides that constitute (or include) biologically active variants of those fragments. Sequence-specific formulas are provided herein, and polypeptides conforming to those formulas, as well as nucleic acids encoding them, expression vectors, host cells, pharmaceutical formulations, and methods of their preparation and use are within the scope of the present invention.
    Type: Grant
    Filed: December 7, 2011
    Date of Patent: December 13, 2016
    Assignee: The Research Foundation For The State University of New York
    Inventor: Srinivas Pentyala
  • System and method for generating three-dimensional images from two-dimensional bioluminescence images and visualizing tumor shapes and locations
    Patent number: 9519964
    Abstract: A system and methods for generating 3D images from 2D bioluminescent images and visualizing tumor locations are provided. A plurality of 2D bioluminescent images of a subject are acquired using any suitable bioluminescent imaging system. The 2D images are registered to align each image and to compensate for differences between adjacent images. After registration, corresponding features are identified between consecutive sets of 2D images. For each corresponding feature identified in each set of 2D images, an orthographic projection model is applied, such that rays are projected through each point in the feature. The intersection points of the rays are plotted in a 3D image space. All of the 2D images are processed in the same manner, such that a resulting 3D image of a tumor is generated.
    Type: Grant
    Filed: July 10, 2012
    Date of Patent: December 13, 2016
    Assignee: Rutgers, The State University of New Jersey
    Inventors: Dimitris Metaxas, Debabrata Banerjee, Xiaolei Huang
  • Identification and use of genes encoding amatoxin and phallotoxin
    Patent number: 9518097
    Abstract: The present invention relates to compositions and methods comprising genes and peptides associated with cyclic peptide toxins and toxin production in mushrooms. In particular, the present invention relates to using genes and proteins from Amanita species encoding Amanita peptides, specifically relating to amatoxins and phallotoxins. In a preferred embodiment, the present invention also relates to methods for detecting Amanita peptide toxin genes for identifying Amanita peptide-producing mushrooms and for diagnosing suspected cases of mushroom poisoning. Further, the present inventions relate to providing kits for diagnosing and monitoring suspected cases of mushroom poisoning in patients.
    Type: Grant
    Filed: November 10, 2008
    Date of Patent: December 13, 2016
    Assignee: Board of Trustees of Michigan State University
    Inventors: Heather E. Hallen, Jonathan D. Walton, Hong Luo, John S. Scott-Craig
  • Use of Melanocortins to Treat Insulin Sensitivity
    Publication number: 20160354429
    Abstract: The present invention relates to peptide ligands of the melanocortin receptors, in particular the melancortin-4 receptor, and as such, are useful in the treatment of disorders responsive to the activation of this receptor, such as insulin resistance.
    Type: Application
    Filed: August 22, 2016
    Publication date: December 8, 2016
    Applicants: Ipsen Pharma S.A.S., Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
    Inventors: Heather A. HALEM, Michael DeWitt CULLER, Andrew A. BUTLER
  • COMPOUNDS COMPRISING A HIBONITE STRUCTURE AND A METHOD FOR THEIR USE
    Publication number: 20160355407
    Abstract: Novel colored compounds with a hibonite structure and a method for making the same are disclosed. The compounds may have a formula AAl12-x-yMaxMbyO19 where A is typically an alkali metal, an alkaline earth metal, a rare earth metal, Pb, Bi or any combination thereof, and Ma is Ni, Fe, Cu, Cr, V, Mn, or Co or any combination thereof, and Mb is Ti, Sn, Ge, Si, Zr, Hf, Ga, In, Zn, Mg, Nb, Ta, Sb, Mo, W or Te or any combination thereof. Compounds with varying colors, such as blue, can be made by varying A, Ma and Mb and their relative amounts. Compositions comprising the compounds and methods for making and using the same are also disclosed.
    Type: Application
    Filed: August 16, 2016
    Publication date: December 8, 2016
    Applicant: OREGON STATE UNIVERSITY
    Inventors: MUNIRPALLAM A. SUBRAMANIAN, ARTHUR W. SLEIGHT, JUN LI