Patents Assigned to Technion Research & Development
  • Publication number: 20230170909
    Abstract: A method of using memristor aided logic (MAGIC), comprises connecting together two input and one output memristor between a bit line and a word line, each memristor having a high resistance state and a low resistance state, setting the output memristor to the low resistance state as an initiation state and then applying logic inputs to the input memristors. The output then depends on whether the logic inputs have set the output memristor to the high resistance state.
    Type: Application
    Filed: April 7, 2021
    Publication date: June 1, 2023
    Applicant: Technion Research & Development Foundation Limited
    Inventors: Shahar KVATINSKY, Barak HOFFER
  • Publication number: 20230158208
    Abstract: A scaffold comprising electrospun decellularized ECM of an organ, wherein the decellularized ECM has a similar protein composition to native ECM of the organ. Methods of generating same are also disclosed as well as uses of same.
    Type: Application
    Filed: January 23, 2023
    Publication date: May 25, 2023
    Applicant: Technion Research & Development Foundation Limited
    Inventors: Marcelle MACHLUF, Eyal ZUSSMAN, Limor BARUCH
  • Patent number: 11653871
    Abstract: A method comprising: receiving a plurality of data segments each representing human cardiac activity; calculating, from each of said data segments, a first value representing a distribution of a heart rate variability (HRV) parameter; acquiring a signal representing cardiac activity in a patient; deriving a second value representing distribution of an HRV parameter in said signal; and indicating an atrial fibrillation (AF) event in said patient, when a difference between said first and second values is above a predetermined threshold.
    Type: Grant
    Filed: March 7, 2019
    Date of Patent: May 23, 2023
    Assignee: TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED
    Inventors: Yael Yaniv, Noam Keidar, Yonatan Elul
  • Publication number: 20230155590
    Abstract: An electronic memory block comprises phase change memory cells for memory storage and further phase change memory cells forming logic gates, to provide in-memory data processing.
    Type: Application
    Filed: April 7, 2021
    Publication date: May 18, 2023
    Applicant: Technion Research & Development Foundation Limited
    Inventors: Shahar KVATINSKY, Barak HOFFER, Eilam YALON, Nicolas WAINSTEIN
  • Patent number: 11648260
    Abstract: The present invention provides pharmaceutical compositions comprising membrane vesicles, including extracellular vesicles including those referred to as exosomes, loaded with an exogenous Phosphatase and tensin homolog (PTEN) inhibitor. Methods of treating neurological diseases, disorders or conditions using the extracellular vesicles are provided. Isolated extracellular vesicles loaded with an exogenous Phosphatase and tensin homolog (PTEN) inhibitor are provided as well.
    Type: Grant
    Filed: March 27, 2019
    Date of Patent: May 16, 2023
    Assignees: TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LIMITTED, RAMOT AT TEL-AVIV UNIVERSITY LTD.
    Inventors: Shulamit Levenberg, Shaowei Guo, Daniel Offen, Nisim Perets
  • Patent number: 11646793
    Abstract: An electro-optic system, the electro-optic system that may include an input port that is configured to receive a bandpass signal that conveys information; wherein the bandpass signal is a radio frequency (RF) signal; an optical carrier source that is configured to generate an optical carrier signal having an optical carrier frequency; at least one electrical bias circuit that is configured to generate at least one electrical bias signal; an electro-optic modulation circuit that is linear at the optical field; a manipulator that is configured to (a) receive the at least one electrical bias signal and the bandpass signal, (b) generate, based on the at least one electrical bias signal and the bandpass signal, at least one modulating signal; wherein the electro-optic modulation circuit is configured to modulate the optical carrier by the at least one modulating signal to provide an output optical signal that comprises at least one optical pilot tone and at least one optical sideband that conveys the information.
    Type: Grant
    Filed: March 15, 2021
    Date of Patent: May 9, 2023
    Assignee: TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LIMITED
    Inventors: Moshe Nazarathy, Amos Agmon, Alexander Tolmachev
  • Publication number: 20230134408
    Abstract: A process of preparing a conductive oxide interface is described herein, comprising contacting a surface of a first oxide with a plasma of a reducing gas to obtain a treated surface, and depositing a second oxide on the treated surface, thereby obtaining a conductive oxide interface between the first oxide and the second oxide. Further described herein are composites and articles of manufacture comprising same, the composites comprising a first oxide and second oxide, and an interface between the first oxide and second oxide which comprises a conductive oxide interface, wherein the conductive oxide interface comprises nitrogen atoms and/or the second oxide is in an amorphous form and the conductive oxide interface is characterized by a sheet resistance of no more than 105 omega/square.
    Type: Application
    Filed: April 15, 2021
    Publication date: May 4, 2023
    Applicant: Technion Research & Development Foundation Limited
    Inventors: Lior KORNBLUM, Dana COHEN AZARZAR, Maria BASKIN, Yang LI
  • Patent number: 11639369
    Abstract: The present invention is directed to a cyclic polypeptide having ubiquitin binding affinity (KD) of 0.1-100 nM. Further provided are methods for reducing deubiquitination activity of a cell, and for treating cancer in a subject in need thereof.
    Type: Grant
    Filed: June 6, 2019
    Date of Patent: May 2, 2023
    Assignees: TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED, THE UNIVERSITY OF TOKYO
    Inventors: Ashraf Brik, Mickal Nawatha, Hiroaki Suga, Joseph Rogers
  • Patent number: 11633434
    Abstract: Kits and composition comprising: (i) a thermo-responsive hydrogel characterized by a viscosity suitable for hardening after administration on a subject's skin; (ii) a bacterial growth medium; and optionally, (iii) a population of non-pathogenic viable bacteria, are provided. Methods for topically delivering a therapeutic or cosmeceutical agent such as for inhibiting or reducing growth of microorganisms on a subject's skin are further provided.
    Type: Grant
    Filed: September 6, 2018
    Date of Patent: April 25, 2023
    Assignee: TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED
    Inventors: Boaz Mizrahi, Maayan Lufton
  • Patent number: 11630808
    Abstract: A method of applying proof of lottery to select block forgers in a blockchain, comprising performing the following at a certain one of a plurality of computing nodes connected to a blockchain network: (1) transmitting one or more of a plurality of participation transactions submitted by at least some of the plurality of computing nodes for participating in selection process conducted to select forgers from the plurality of computing nodes to forge blocks to be added to the blockchain; (2) determining a respective forger, during each selection process, by applying a selection function to an outcome of a hash function and a plurality of participation transactions extracted from a first subset of blocks preceding the respective block, the hash function is applied to a second subset of blocks preceding the respective block; and (3) forging the respective block in case the certain computing node is selected as the respective forger.
    Type: Grant
    Filed: May 3, 2021
    Date of Patent: April 18, 2023
    Assignee: Technion Research & Development Foundation Limited
    Inventor: Oded Shmueli
  • Patent number: 11631035
    Abstract: Disclosed embodiments are a computing system and a computer-implemented method for distributed training of a machine learning model over a plurality of computing nodes, in a plurality of iterations, characterized by gradient gap based mitigation of the gradient staleness problem. The disclosed method evaluates the staleness of the gradient based on the difference in gradients between a central point, for example an iteration's common starting point, and the points reached by the respective computing node during one or more iterations, and aggregates the update steps from the plurality of computing nodes, while giving more weight to computing nodes having a lesser change in the gradient.
    Type: Grant
    Filed: November 5, 2020
    Date of Patent: April 18, 2023
    Assignee: Technion Research & Development Foundation Limited
    Inventors: Assaf Schuster, Saar Barkai, Ido Hakimi
  • Publication number: 20230113487
    Abstract: Conjugates of fibrinogen and a plurality of curable groups covalently attached thereto, and curable formulations comprising such conjugates, are provided. Also provided are three-dimensional objects (scaffolds) made of the conjugate or the curable formulation, for example, by additive manufacturing, and uses thereof in, for example, tissue healing and/or regeneration.
    Type: Application
    Filed: October 7, 2022
    Publication date: April 13, 2023
    Applicant: Technion Research & Development Foundation Limited
    Inventors: Dror SELIKTAR, Haneen SIMAAN-YAMEEN
  • Patent number: 11619543
    Abstract: Apparatus is provided including an acoustic sensor (50) having an optical waveguide (20). The optical waveguide (20) includes a waveguide core (202) having a waveguide core refractive index and a waveguide core photo-elastic coefficient, and an over-cladding layer (204) coupled to the waveguide core (202) and including an optically transparent polymer having an over-cladding refractive index and an over-cladding photo-elastic coefficient. The waveguide core refractive index is greater than the over-cladding refractive index, and the over-cladding photo-elastic coefficient is greater than the waveguide core photo-elastic coefficient. Other applications are also described.
    Type: Grant
    Filed: August 20, 2019
    Date of Patent: April 4, 2023
    Assignee: TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED
    Inventors: Amir Rozental, Resmi Ravi Kumar, Shai Tsesses, Assaf Grinberg
  • Patent number: 11620752
    Abstract: A method comprising: receiving an image of a scene, segmenting the image into a plurality of segments, obtaining at least one depth sample from each of at least some of the segments, and with respect to each of the at least some of the segments, assigning a value of the depth sample to each pixel in the segment, to create a depth image of the image.
    Type: Grant
    Filed: June 2, 2020
    Date of Patent: April 4, 2023
    Assignee: TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED
    Inventors: Guy Gilboa, Adam Wolff, Shachar Praisler, Ilya Tcenov, Yossi Bar Erez
  • Publication number: 20230100365
    Abstract: A method for automatic determining of a state of a heart of a patient based on multiple-lead ECG information of the patient, the method includes (a) receiving the multiple-lead ECG information of the patient, by a computerized system; and (b) applying one or more machine learning processes on the multiple-lead ECG information of the patient to determine the state of a heart of the patient, wherein the state of the heart comprises at least one heart condition of multiple types of heart conditions. One, some or all of the one or more machine learning processes was trained using a dataset that comprises multiple computer generated images, the multiple computer generated images represent images acquired by an image acquisition process of ECG plots, wherein the ECG plots are generated based on digital multiple-lead ECG signals.
    Type: Application
    Filed: September 28, 2022
    Publication date: March 30, 2023
    Applicant: Technion Research and Development Foundation Ltd.
    Inventors: Yael Yaniv Schuster, Assaf Schuster, Vadim Gliner
  • Publication number: 20230095010
    Abstract: The invention provides a method for treating cancer comprising the step of administering a therapeutically effective amount of KPC1, a peptide which is at least about 70% homologous to the KPC1 or an agent which up-regulates KPC1. In some embodiments, there is also provided a method for treating cancer comprising the step of administering a therapeutically effective amount of p50, a peptide which is at least about 70% homologous to the p50 or an agent which up-regulates p50.
    Type: Application
    Filed: August 15, 2022
    Publication date: March 30, 2023
    Applicant: Technion Research & Development Foundation Limited.
    Inventors: Aaron CIECHANOVER, Yelena KRAVTSOVA, Inna SHOMER, Victoria COHEN
  • Patent number: 11611352
    Abstract: A digital to analog converter is constructed using a neural network layer. The converter has inputs for receiving parallel bits of a digital input signal and an output for outputting an analog signal which is based on the digital input. Connecting the input and the output is a neural network layer which is configured to convert the parallel bits into an output analog signal that is representative of the digital input signal. The neural network may be hardwired and the synapses may rely on memristors as programmable elements.
    Type: Grant
    Filed: July 11, 2018
    Date of Patent: March 21, 2023
    Assignee: Technion Research & Development Foundation Limited
    Inventors: Shahar Kvatinsky, Loai Danial
  • Patent number: 11609217
    Abstract: A method for sensing gas by a gas sensing device, the method may include generating, by a semiconductor temperature sensing element that is spaced apart from a gas reactive element and is thermally coupled to the gas reactive element, detection signals that are indicative of a temperature of the gas reactive element; wherein the gas reactive element and the semiconductor temperature sensing element are of microscopic scale; and processing, by a readout circuit of the gas sensing device, the detection signals to provide information about a gas that affected the temperature of the gas reactive element.
    Type: Grant
    Filed: September 4, 2020
    Date of Patent: March 21, 2023
    Assignees: Todos Technologies Ltd., TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD.
    Inventors: Yael Nemirovsky, Amikam Nemirovsky, Shmuel Melman
  • Publication number: 20230070921
    Abstract: There may be provided method for estimating an information unit represented by a cluster of traces that are noisy copies of a synthesized strand, the method may include estimating the information unit by applying processing operations on r-tuples related to the traces, wherein r is smaller than a number (t) of traces of the cluster; wherein processing operations applied on at least some of the r-tuples comprise calculating a length of a shortest common supersequences (SCS) of the r-tuples.
    Type: Application
    Filed: September 8, 2021
    Publication date: March 9, 2023
    Applicant: TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD.
    Inventors: OMER SABARY, GUY SHAPIRA, EITAN YAAKOBI, ALEXANDER YUCOVICH
  • Patent number: 11601602
    Abstract: A method comprising receiving data representing light intensity values corresponding to a flicker pattern of a reference light source powered by an alternating current (AC); operating a controllable illumination source, based, at least in part, on said data; capturing, using an imaging device, a sequence of images of a scene illuminated, at least in part, by said controllable illumination source; estimating an intensity value for at least one pixel in said array, correspondingly in each of said images in said sequence of images; and determining a temporal point in said flicker pattern of said reference light source, based, at least in part, on said estimating.
    Type: Grant
    Filed: June 20, 2019
    Date of Patent: March 7, 2023
    Assignees: TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED, THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO
    Inventors: Mark Sheinin, Yoav Schechner, Yoash Levron, Kiriakos Neoklis Kutulakos