Abstract: There is provided a method of computing lineage, comprising: managing a dataset of records, each record associated with set(s) of vectors of real numbers that encode an approximation of lineage of the respective record, the set(s) of vectors computed by an encoding process, obtaining result record(s) in response to executing a query on the dataset, computing set(s) of vectors for the result record(s), searching the set(s) of vectors on the records of the dataset to identify a record associated with a subset of vectors that are statistically similar to the set(s) of vectors for the result record(s), and providing a subset of the records corresponding to the identified subset of records, the subset of the records having a likelihood of contributing to the existence of the result record(s) in response to execution of the query.
Type:
Application
Filed:
August 16, 2022
Publication date:
March 2, 2023
Applicant:
Technion Research & Development Foundation Limited
Abstract: Well-defined, xeno-free culture media which comprise a TGF-beta isoform or the chimera formed between IL6 and the soluble IL6 receptor (IL6RIL6), which are capable of maintaining stem cells, and particularly, human embryonic stem cells, in an undifferentiated state are provided. Also provided are cell cultures comprising the culture media and the stem cells and methods of expanding and deriving embryonic stem cells in such well-defined, xeno-free culture media. In addition, the present invention provides methods of differentiating ESCs or EBs formed therefrom for the generation of lineage specific cells.
Type:
Application
Filed:
October 24, 2022
Publication date:
March 2, 2023
Applicant:
Technion Research & Development Foundation Limited
Abstract: Compositions made of laminate comprised of porous carbon nanotube (CNT) are disclosed. Uses of the Compositions, particularly for reducing a formation of a load of a microorganism or of a biofilm, are also disclosed.
Type:
Grant
Filed:
February 22, 2018
Date of Patent:
February 28, 2023
Assignee:
TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED
Inventors:
Carlos George Dosoretz, Avner Ronen, Chidambaram Thamaraiselvan, Sofia Lerman Roytblat
Abstract: An ultrasound detection device comprising: an ultrasound receiver configured to generate a signal indicative of a pressure of ultrasound that impinges on the receiver; and a coded mask comprising an ultrasound-blocking material perforated by an array of a plurality of apertures, the apertures arranged such that when the coded mask is placed over the receiver between the receiver and a source of ultrasound in a predetermined lateral position, the ultrasound is transmitted from the ultrasound source to the receiver via a known unique pattern of active apertures of the plurality of apertures such that the signal that is generated by the receiver is a multiplexed signal.
Type:
Grant
Filed:
September 24, 2020
Date of Patent:
February 28, 2023
Assignee:
TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED
Abstract: A submersible vehicle comprising: an image sensor; a first illuminator; at least one hardware processor operatively coupled with said image sensor and first illuminator, and the at least one hardware processor being configured to: acquire a first image of a scene inside a medium, when there is no object along the line-of-sight (LOS), under illumination from a first location or orientation, acquire a second image of the scene inside the medium, when there is no object along the LOS, under illumination from a second, different location or orientation, and compute attenuation coefficients, one per color channel, based on backscatter in the first and second images.
Type:
Grant
Filed:
July 12, 2021
Date of Patent:
February 21, 2023
Assignees:
CARMEL HAIFA UNIVERSITY ECONOMIC CORPORATION LTD., TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED
Abstract: The ubiquitin ligase, RNF5, regulates the gut microbiota composition and influences the immune checkpoint response to tumors. RNF5 deficient animals exhibit significant inhibition of tumor development as well as an altered gut microbiota composition. Methods of treating cancer by administering to a subject one or more selected bacterial species and/or one or more prebiotics that promote the growth of one or more selected bacterial species are disclosed. Also disclosed are methods of treating cancer by administering to a subject one or more selected bacterial species and/or one or more prebiotics that promote the growth of one or more selected bacterial species in combination with one or more anti-cancer agents.
Type:
Grant
Filed:
November 17, 2017
Date of Patent:
February 7, 2023
Assignees:
Sanford Bumham Prebys Medical Discovery Institute, Technion Research & Development Foundation Ltd.
Inventors:
Yan Li, Scott Peterson, Linda Bradley, Roberto Tinoco, Ze'ev Ronai, Shiri Ashkenazi
Abstract: A system and a method for separation of ions from ions-containing medium is disclosed herein, that utilizes capacitive-faradaic fuel cells (CFFC) particles coated at least partially with catalysts capable of catalyzing redox reactions provided a reductant (fuel) and/or an oxidant, thereby polarizing the particles to more effectively absorb charged species (ions) from the water upon introducing, e.g., H2 gas or O2 gas, in the medium during the adsorption or regeneration. The same concept is utilized in a hybrid electrochemical cell for providing a system and a method for generating and converting electrochemical energy.
Type:
Application
Filed:
March 1, 2021
Publication date:
January 26, 2023
Applicant:
Technion Research & Development Foundation Limited
Abstract: The present invention provides a self-healing field-effect transistor (FET) device comprising a self-healing substrate and a self-healing dielectric layer, said substrate and said layer comprising a disulfide-containing poly(urea-urethane) (PUU) polymer, wherein the dielectric layer has a thickness of less than about 10 ?m, a gate electrode, at least one source electrode, and at least one drain electrode, said electrodes comprising electrically conductive elongated nanostructures; and at least one channel comprising semi-conducting elongated nanostructures. Further provided is a method for fabricating the FET device.
Type:
Grant
Filed:
August 20, 2019
Date of Patent:
January 24, 2023
Assignee:
TECHNION RESEARCH AND
DEVELOPMENT FOUNDATION LTD.
Abstract: A composite comprised of: (i) at least one inverse freezing material, and (ii) an additive in the form of at least one solid particle. Articles made of the composites, and uses of the composites or the articles incorporating same, particularly for reducing incoming shockwaves, are also disclosed.
Type:
Grant
Filed:
May 27, 2021
Date of Patent:
January 17, 2023
Assignee:
TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED
Inventors:
Galit Parvari, Daniel Rittel, Yonatan Rotbaum, Yoav Eichen
Abstract: A modular robotic surgical system comprising: a base; a plurality of tool-receivers arranged as separate units, each tool-receiver unit operable to move an elongate surgical tool received therein; a plurality of interface coupling pairs, each coupling pair comprising a first coupler as part of the base and a second coupler as part of each of the tool-receiver units; wherein each of the tool-receiver units is independently and interchangeably attachable to the base via the coupling pair.
Type:
Application
Filed:
November 26, 2020
Publication date:
January 12, 2023
Applicants:
Microbot Medical Ltd., Technion Research & Development Foundation Limited
Inventors:
Simon SHARON, Idan BOADER, Evgeny KOFMAN, Eran COHEN, Eyal MORAG, Harel GADOT, Moshe SHOHAM
Abstract: A method for detecting or monitoring respiratory or cardiac health of a patient includes measuring any intravascular or intracardiac pressure (IVP) of a patient over a period of time, said IVP including a measured respiratory wave, defining respiratory effort of the patient as a peak-to-peak amplitude of said respiratory wave, and using the respiratory effort to detect or monitor respiratory and cardiac health of the patient by comparing the respiratory effort with a known value of respiratory effort or by monitoring changes in the respiratory effort of the patient over another period of time.
Type:
Grant
Filed:
May 29, 2020
Date of Patent:
January 10, 2023
Assignee:
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD.
Inventors:
Amir Landesberg, Anna Faingersh-Klebanov
Abstract: A compositions-of-matter in the form of HIPE-templated hydrogels, comprising a crosslinked polymer of zwitterionic monomers, which exhibit unusual antipolyelectrolyte characteristics, dual pH-, and temperature-responsiveness, as well as processes of obtaining the same and using the same.
Type:
Grant
Filed:
October 30, 2018
Date of Patent:
January 10, 2023
Assignee:
Technion Research & Development Foundation Limited
Abstract: A spectrally encoded flow cytometry (SEFC) technique for imaging blood in the microcirculation. Since the dependency of one of the axes of the image on time prevents effective quantification of essential clinical parameters, the optical path in an SEFC system is split into two parallel imaging lines, followed by data analysis for recovering the flow speed from the multiplexed data. The data analysis may be auto-correlation of a pair of images obtained from a sequence of images of the imaged blood vessel.
Type:
Grant
Filed:
June 3, 2020
Date of Patent:
January 10, 2023
Assignee:
TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED
Abstract: There may be provided a radiation sensing device that includes a first TMOS with temperature dependent electrical parameters; wherein the first TMOS is exposed to radiation, and a second TMOS transistor that is sheltered from radiation. The radiation sensing device performs a differential measurement, and applied various measures for noise reduction, and maintaining the stability of the radiation sensing device.
Type:
Grant
Filed:
July 2, 2021
Date of Patent:
January 10, 2023
Assignee:
Technion Research and Development Foundation Ltd.
Inventors:
Yael Nemirovsky, Sharon Bar-Lev Shefi, Igor Brouk
Abstract: Protein based highly stretchable compositions with ionic conductivity are disclosed herein. Methods for preparing such compositions are also disclosed.
Type:
Application
Filed:
October 29, 2020
Publication date:
January 5, 2023
Applicant:
TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED
Abstract: There is provided a method of representing a three dimensional (3D) object using univariate curves, comprising: receiving an initial definition of a 3D object representation, calculate a covering set of univariate curves, the covering set comprising at least one non-planar univariate curve, wherein the covering set of univariate curves represent the volume of the 3D object within a tolerance requirement, and generating a representation of the 3D object based on the set of univariate curves, wherein the set of univariate curves represent the volume of the 3D object.
Type:
Grant
Filed:
June 10, 2021
Date of Patent:
January 3, 2023
Assignee:
Technion Research & Development Foundation Limited
Abstract: A method comprising: receiving a plurality of pairs of queries associated with a database, wherein the queries in each pair in the plurality of pairs of queries have an identical FROM clause; at a training stage, training a machine learning model on a training set comprising: (i) the plurality of pairs of queries, and (ii) labels associated with containment rates between each of the pairs of queries over the database; and at an inference stage, applying the trained machine learning model to a pair of target queries, to estimate containment rates between the target pair of queries over the database.
Type:
Grant
Filed:
August 19, 2020
Date of Patent:
December 20, 2022
Assignee:
TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED
Abstract: The present invention is directed to methods and kits for determining the presence of a mutated SLC30A2 polynucleotide. The invention is further directed to methods of determining a subject's genetic-susceptibility to zinc deficiency and evaluating zinc levels in a composition comprising breast milk.
Type:
Grant
Filed:
April 11, 2018
Date of Patent:
December 20, 2022
Assignee:
TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED
Abstract: A narrow channel Hall thruster comprising a thruster body with a magnetic circuit, an annular thruster channel having a channel width of less than 3 mm formed within the magnetic circuit, an annular anode, a cathode positioned externally to the thruster, and configured for electron emission, a power supply applying a positive potential to the anode, such that a plasma discharge can be generated in the annular thruster channel, and another power supply applying a negative potential to the cathode, relative to the thruster body and the anode. The second power supply reduces its negative voltage output to the cathode when the current supplied by the anode power supply exceeds a predetermined level, indicating that the discharge has reached a stable initiated condition. The reduction of the voltage output of the second power supply can be achieved either by self-regulation, or by use of a current limit circuit.
Type:
Grant
Filed:
February 13, 2020
Date of Patent:
December 20, 2022
Assignee:
TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD.
Abstract: A polyHIPE-based substance-releasing system capable of releasably encapsulating a highly concentrated solution and/or a room temperature solid while minimizing or avoiding burst release from the closed-cell microstructure of an elastic polyHIPE.
Type:
Grant
Filed:
August 16, 2017
Date of Patent:
December 20, 2022
Assignee:
Technion Research & Development Foundation Limited
Inventors:
Michael S. Silverstein, Katya Kapilov-Buchman, Reinhard Effenberger, Dorit Canfi