Abstract: A system includes a treatment apparatus configured to implement a treatment plan for rehabilitation to be performed by a user and a processing device configured to receive attribute data associated with the user; generate, based on the rehabilitation, selected attribute data; determine, based on the selected attribute data, the rehabilitation, and a rehabilitation goal associated with the rehabilitation, one or more probabilities of attaining the rehabilitation goal within respective one or more numbers of rehabilitation sessions to be performed by the user using the treatment apparatus; provide, based on the one or more probabilities, an indication of the one or more numbers of rehabilitation sessions; and generate, based on a selected number of rehabilitation sessions from among the one or more numbers of rehabilitation sessions, the treatment plan. The treatment plan includes one or more exercises directed to attaining the rehabilitation goal within the selected number of rehabilitation sessions.

Abstract: This invention pertains to mutant Cas9 nucleic acids and proteins for use in CRISPR/Cas endonuclease systems, and their methods of use. In particular, the invention pertains to an isolated mutant Cas9 protein, wherein the isolated mutant Cas9 protein is active in a CRISPR/Cas endonuclease system, wherein the CRISPR/Cas endonuclease system displays reduced off-target editing activity and maintained on-target editing activity relative to a wild-type CRISPR/Cas endonuclease system. The invention also includes isolated nucleic acids encoding mutant Cas9 proteins, ribonucleoprotein complexes and CRSPR/Cas endonuclease systems having mutant Cas9 proteins that display reduced off-target editing activity and maintained on-target editing activity relative to a wild-type CRISPR/Cas endonuclease system.

Abstract: System and method for determining an updated location of a bottom hole assembly (BHA) during drilling of a well are provided. During drilling, a computer system may receive tool face updates and may determine build rate estimates and a borehole depth increase during a toolface update period. The computer system may also calculate an updated estimate of the borehole position.

Abstract: In some examples, an apparatus may include a retention time (RT) receiver that is executed by at least one hardware processor, to receive glucose ladder retention times (RTs), and receive neutral and charged glycan RTs. An RT analyzer that is executed by the at least one hardware processor may determine, based on application of the glucose ladder RTs, and the neutral and charged glycan RTs to expected glucose unit (GU) values, adjusted GU values. Further, an expected RT generator that is executed by the at least one hardware processor may determine, based on the adjusted GU values, expected RTs for specified glycans.

Abstract: Phytogenic compositions with an essential oil core and one or more additives are added to drinking water to support post-weaning (PW) piglets. The PW piglets provided drinking water supplemented with the phytogenic compositions have reduced mortality rates in a nursery. The essential oil core includes two essential oils. The two essential oils are eugenol and tea tree oil.

Abstract: Various aspects are directed to a data storage device comprising one or more disks, an actuator mechanism configured to position a selected head among one or more heads proximate to a corresponding disk surface among the one or more disks, and one or more processing devices. The one or more processing devices are configured to detect repeatable runout (RRO) noise components from a measurement of fly height of the selected head above one or more sectors of a fly height measurement track, and remove the detected RRO noise components from one or more per-sector readback signal measurements.

Abstract: An adaptive frequency sweeping method and an adaptive frequency sweeping system for frequency point sampling, and related devices, related to a technical field of wireless communication are provided, the adaptive frequency sweeping method is applied to simulation of radio frequency (RF) components. The adaptive frequency sweeping method for the frequency point sampling does not hinge upon specific numerical values and enables precise simulation at positions where frequency responses rapidly change while performing coarse simulation in areas that are not concerned about, thereby improving precision and efficiency of a design process for the RF components. Moreover, aiming at characteristics of Y parameters and S parameters in the frequency responses, different evaluation metrics are provided to reduce sampling points required for frequency sweeping and increasing a frequency sweeping speed.

Abstract: Novel tools and techniques are provided for implementing optimized scheduling of tasks involving equipment used by multiple individuals. In various embodiments, a computing system might receive, from a first user, a first request to use first equipment that is disposed in a work environment, the first request comprising information regarding a first task to be performed using the first equipment. The computing system might determine a core processing time during which the requested first equipment performs core processes involved with performing the first task, might determine a pre-processing time and a post-processing time involved with performance of the first task. The computing system might determine an estimated total processing time to complete the first task using the first equipment, based on the determined core processing time, pre-processing time, and post-processing time. The computing system might display the estimated total processing time to complete the first task using the first equipment.

Abstract: The disclosure provides a device for measuring serum bilirubin levels and uses thereof. The device includes a plate including a surface comprising: a stepwise gradient of colors; a lighting indicator; and a series of windows in the surface, each window in the series bordered by one of the colors, and each window including a transparent portion in the plate.

Abstract: A hemostatic material and a method of treating a bleeding wound of a human or an animal include a hemostatic powder for application to the wound. The hemostatic powder comprises a first part consisting of a native chitosan base and a second part consisting of a chitosan salt, where the first and the second parts form the main component of the hemostatic powder, or at least 50% of a total weight of the hemostatic powder, and the second part forms a layer that at least partially coats the first part. The hemostatic powder may be provided in a hemostatic spray formulation that comprises a mixture of the hemostatic powder dispersed in a liquefied gas for release from a cannister onto the wound. A treatment method involves applying the hemostatic spray formulation directly to the wound. Other embodiments are also disclosed.

Abstract: The present disclosure provides a flow control equipment and an automatic refilling system. The flow control equipment includes: a housing, including a discharge hole in a bottom of the housing; a liquid inlet tube connecting with a top of the housing; a motor located in the housing; a flow locking blade and a plurality of flow control blades connected to the motor, where leakage holes of different sizes are formed in the flow control blades, and the motor drives the flow control blades and the flow locking blade to rotate to align the different leakage holes with the discharge hole, or to seal the discharge hole; and a liquid outlet tube connecting with the discharge hole.

Abstract: This invention pertains to mutant Lachnospiraceae bacterium ND2006 (Lb) Cas12a nucleic acids and proteins for use in CRISPR/Cas12a endonuclease systems, and their methods of use. In particular, the invention pertains to an isolated mutant LbCas12a protein, wherein the isolated mutant LbCas12a protein is active in a CRISPR/Cas12a endonuclease system. The invention also includes isolated nucleic acids encoding mutant LbCas12a proteins, ribonucleoprotein complexes and CRISPR/Cas12a endonuclease systems having mutant LbCas12a proteins.

Abstract: A self-aligned fabrication process for aligning photonic waveguide layers of a 3D photonic structure such that light may be efficiently transferred between the two layers is described. The self-aligned fabrication process comprises using a mask to pattern both photonic waveguide layers, such that they are aligned three-dimensionally via a single lithographic processing step, and thus fabricating a photonically coupled region of the 3D photonic structure. Selective etching may also be used to taper a given photonic waveguide layer for adiabatic coupling, and/or to produce other non-trivial geometric shapes in the photonic waveguide layers. Such 3D photonic structures may be fabricated for use in quantum memory devices, in which one of the photonic waveguide layers may host quantum memories and another photonic waveguide layer may interface with an optical fiber, such that light may be transferred between an optical fiber and respective ones of the quantum memories.

Abstract: Dies and/or wafers are stacked and bonded in various arrangements including stacks, and may be covered with a molding to facilitate handling, packaging, and the like. In various examples, the molding may cover more or less of a stack, to facilitate connectivity with the devices of the stack, to enhance thermal management, and so forth.

Abstract: Systems and methods of in vivo and in vitro radical protein foot-printing using an opto-fluidic array are presented. These teachings may be used to, for example, study three-dimensional protein structure or bio-kinetics. Radical dosimetry including an optional intrinsic standard is used. Real-time feedback based on an internal standard provides comparability between different experiments and in vivo and in vitro analysis results in data that is representative of actual biological conditions.

Abstract: A capacitor structure and a method of manufacturing the same, and a memory are provided. The method includes the following operations. A substrate is provided. A first conductive structure with a shape of column is formed on the substrate. A second conductive structure is formed on the substrate. The second conductive structure surrounds the first conductive structure and is spaced with the first conductive structure. The first conductive structure and the second conductive structure together form a bottom electrode. A capacitor dielectric layer is formed. The capacitor dielectric layer covers the surface of the substrate and the surface of the bottom electrode. A top electrode covering the surface of the capacitor dielectric layer is formed.

Abstract: In various embodiments, a method for forming a bonded structure is disclosed. The method can comprise mounting a first integrated device die to a carrier. After mounting, the first integrated device die can be thinned. The method can include providing a first layer on an exposed surface of the first integrated device die. At least a portion of the first layer can be removed. A second integrated device die can be directly bonded to the first integrated device die without an intervening adhesive.

Abstract: An amplification circuit includes: a sense amplification circuit including a read node, a complementary read node, a first node and a second node; an isolation circuit, which couples the read node to a bit line and couples the complementary read node to a complementary bit line in a sense amplification stage; an offset cancellation circuit, which couples the bit line to the complementary read node and couple the complementary bit line to read node in an offset cancellation stage; and a first power supply circuit, coupled to the first node, including a first power supply and a second power supply, a power supply voltage of the first power supply being higher than that of the second power supply, the first power supply circuit couples the first power supply to the first node in offset cancellation stage, and couples the second power supply to the first node in sense amplification stage.