Abstract: A method and computer-based system is provided that assists physicians in detecting early tumor growth and allowing modification of treatment to have a positive impact on medical management, patient morbidity, outcomes and survival times. The method comprises measuring tumor volumes from radiological images to predict growth by a statistical method. The methods allow detection of increases in tumor size earlier than is currently possible and, therefore, advantageous in modifying or optimizing treatment.

Abstract: The present invention belongs to the field of power system operations and provides a method for quantifying the flexibility demand and coordinating optimization of a hydro-wind-solar multi-energy complementary system. Firstly, the flexibility demand quantification method considering the uncertainty of wind and solar power output is constructed, and the wind and solar power output interval is divided by using quantile points to generate a set of output scenarios, and then the flexibility demand under each scenario is calculated. Based on the quantitative index of flexibility demand, an optimal operation model of hydro-wind-solar complementary system considering the minimum expectation of system flexibility deficiency is constructed to realize the optimal calculation of hydro-wind-solar complementary. By utilizing an actual wind-hydro complementary system of the Yunnan Power Grid, the model is validated for different new energy access ratios.

Abstract: A genus of compounds encompassed by formula (III) and their use is disclosed: The compounds activate Ppargc1a and, as a consequence, are useful for treating a variety of neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS), Alzheimer's disease, Parkinson's disease, Huntington's disease, frontotemporal degeneration, dementia with Lewy bodies, motor neuron diseases, and a demyelinating disease.

Abstract: Polyimide membranes including polyimide structures selected from the group including: wherein n is an integral number where 2?n?100, i.e., an integer between and including 2 and 100, or an integer between 2 and 100.

Abstract: A training method of underwater sea urchin image recognition model, and underwater sea urchin image recognition method and device are provided. The training method includes: constructing an underwater sea urchin image recognition model, acquiring an underwater sea urchin image dataset; performing MSRCR on the underwater sea urchin image dataset; processing the underwater sea urchin image dataset by a dark channel prior method; performing image fusion to obtain a fused image dataset; sharpening the fused image dataset to obtain a training image dataset; and training the underwater sea urchin image recognition model by using the training image dataset. By performing MSRCR and dark channel prior processing on the image, and then performing image fusion and sharpening based on a point sharpness weighting method, the quality of image is improved, and an accuracy of subsequent sea urchin object detection is improved.

Abstract: A general mounting method for ducted fan propulsors is disclosed. This mounting method uses extremely slender stators that connect the duct ring to the propulsor which is mounted in the middle and drives the rotor, fan or propeller. The slender stators take the form of spokes and as such are so slender that the midspan stresses within the spokes are dominated by axial tension loads rather than the shear loads experienced by conventional stators. The spokes may have an aerodynamic shape and damping methods may be used to retard spoke vibrations and transmission of engine vibrations to the duct and force. The duct itself is also stiffened by the spoke arrangement, thereby reducing low frequency vibration modes.

Abstract: A method for detecting internal coating defects in a pipe sample with an electromagnetic acoustic transducer sensor. The method includes recording a plurality of Lamb mode scans of the pipe sample with the EMAT sensor, where each Lamb mode scan is measured along a length of the pipe sample in axial alignment with the pipe sample; and processing the Lamb mode scans by applying a singular spectrum analysis to the Lamb mode scans to generate data from which the internal coating defects in the pipe sample are identified. The Lamb mode scans are at a frequency from dispersion curve of from 0.3 to 2 MHz, at a frequency of from 0.4 MHz to 2 MHz, a group velocity of from 1 mm/?s to 3 mm/?s, a phase velocity of from 5 mm/?s to 25 mm/?s, and a wave count of from 3 to 10.

Abstract: Glutamine antagonists and their use for treating oncological, immunological, and neurological diseases are disclosed. Also disclosed are methods for treating an oncological, immunological, infectious or neurological disease or disorder, the method comprising administering to a subject in need of treatment thereof a therapeutically effective amount of a glutamine antagonist of the disclosure or the pharmaceutical composition thereof. Also disclosed are methods of enhancing the effects of an immune checkpoint inhibitor, enabling a subject to respond to an immune checkpoint inhibitor, or enabling the toxicity or the dose or number of treatments with an immune checkpoint inhibitor to be reduced, comprising administering to a subject in need of treatment thereof a therapeutically effective amount of a glutamine antagonist of the disclosure or the pharmaceutical composition thereof, and an immune checkpoint inhibitor.

Abstract: The invention provides a semipermeable composite membrane that reduces an environmental load, and a method of producing the semipermeable composite membrane. A semipermeable composite membrane 100 includes, on a porous support 102, a semipermeable membrane 104 containing a crosslinked polyamide 120 and a cellulose nanofiber 110. A method of producing the semipermeable composite membrane includes obtaining a mixed solution containing the cellulose nanofiber 110, water, and an amine component, and obtaining the semipermeable composite membrane 100 by making the mixed solution be in contact with the porous support 102, thereafter, causing a cross-linking reaction of the amine component in the mixed solution, with the amine component adhering to the porous support 102.

Abstract: Described herein are assays and methods to detect and/or treat a non-responsive or treatment resistant p16 positive tumor in a subject in need thereof. The disclosed method can also involve determining if the subject is HPV positive or negative, whether the HPV is integrated or episomal, and selecting a suitable treatment based on these determinations. Also disclosed herein is a method of treating an oropharyngeal squamous cell carcinoma in a subject using the arrays and methods disclosed herein.

Abstract: A data transmission method is described that includes: receiving transmission feedback for one or more Code Block Groups (CBGs) from a receiver; transmitting one or more Transmission Blocks (TBs) based on the transmission feedback, wherein one of the one or more TBs comprises one or more retransmission CBGs and one or more initial transmission CBGs; in response to the one of the one or more TBs being an uplink transmission TB, obtaining, based on a correspondence between a number of the one or more retransmission CBGs carried by the one of the one or more TBs and scrambling sequences, scrambled information by scrambling a first check bit sequence, wherein the first check bit sequence is generated based on the transmission feedback and Uplink Control Information (UCI); and uplink-transmitting the UCI and the scrambled information.

Abstract: There is described a system for characterizing a physical property of a sample. The system generally has a microelectromechanical system (MEMS) device having a framework, a shuttle member extending along a longitudinal orientation within the framework, a shuttle actuator having obliquely extending arms extending between the framework and the shuttle member, the shuttle actuator configured for expanding the arms upon application of electricity thereacross, said expanding applying a force onto the shuttle member and moving the shuttle member at least partly in the longitudinal orientation, and a socket positioned adjacent a tip of the shuttle member; and a MEMS chip receiving the sample and being configured for insertion into the socket, whereby, when the MEMS chip is received in the socket and loaded with the sample, the force applied onto the shuttle member is transferred into stress internal to the MEMS chip via the tip of the shuttle member.

Abstract: In some embodiments, image content may be presented to a user of a head-mounted device via one or more inward-facing displays of the head-mounted device. Light emitted from one or more infrared diodes may be projected onto an eye of the user via one or more inward-facing infrared devices of the head-mounted device. Reflection data related to a reflection of the infrared-diode-emitted light reflected from the eye may be obtained via the one or more inward-facing infrared devices of the head-mounted device. A machine learning model (e.g., comprising a neural network or other components) may be used to generate an eye-related indication based on the reflection data comprising one or more anomalies.

Abstract: A virtual memory system for managing a virtual memory page table for a central processing unit and a system of encoding a virtual address (VA) is disclosed. The system includes a memory storing an encoded virtual address, a virtual page number having a settable bitfield that is set according to page size and offset, and a virtual memory. The virtual memory addressing circuitry is configured with a zero detector logic circuit and a virtual page number (VPN) multiplexer. The zero detector logic circuit is configured to read bits of the encoded virtual address and outputs the page size. The virtual page number (VPN) multiplexer is configured to select the virtual page number based on the page size and outputs an index to a page table.

Abstract: Methods for assessing efficacy of a treatment for a bestrophinopathy in a subject are provided. In certain embodiments, the subject has two mutant BEST1 alleles. In certain embodiments, the subject has at least one mutant BEST1 allele.

Abstract: The perovskite solar cell (PSC) includes a first layer containing a conducting material coated glass plate as a substrate, a second layer containing copper doped nickel oxide, a third layer containing a perovskite, a fourth layer containing nitrogen (N)-doped graphene quantum dots, a fifth layer containing phenyl-C61-butyric acid methyl ester and a top layer including conductive layer. A method for producing the perovskite solar cell is also discussed.

Abstract: Provided are a biomass-derived carbon particle, and a preparation method and use thereof. The biomass-derived carbon particle includes a non-graphitized biochar and a graphitized biochar; where the non-graphitized biochar and the graphitized biochar each have an oxygen-containing functional group; and the oxygen-containing functional group includes one selected from the group consisting of hydroxyl group, phenolic hydroxyl group, carbonyl group, and ether group.

Abstract: An embodiment of the disclosure provides a plasma coating method of a nanovesicle surface and a plasma jet device for plasma coating of a nanovesicle surface. The plasma coating method of a nanovesicle surface according to an embodiment of the disclosure may be provided as a simple method for changing the surface charge of a nanovesicle from negative to neutral by utilizing the characteristic that when a neutral object meets a negatively charged object, electrons of the neutral object repel electrons of the negatively charged object and the negatively charged object becomes positively charged.

Abstract: The present invention relates to a method for estimating blood pressure from photoplethysmography (PPG) signals. The blood pressure estimation method using the CFR model according to an embodiment of the present invention is characterized in that it comprises the steps of extracting a plurality of blood flow characteristics from PPG signals for training, calculating systolic and diastolic blood pressures from ambulatory blood pressures for training, labeling the systolic and diastolic blood pressures with the plurality of blood flow characteristics to train a cascade forest regression model, and inputting the PPG signals of a target user into the trained cascade forest regression model to determine the systolic and diastolic blood pressures of the target user.

Abstract: Disclosed is a method for analyzing changes in urban economic development characteristics of an urban agglomeration based on nighttime light remote sensing according, including: building a Gross Domestic Product (GDP) spatialization model: spatializing GDP of an urban agglomeration region by using an industry-based modeling approach, modeling spatialization of a primary industry output GDP1 with land use data, and modeling spatialization of a secondary and tertiary industry output GDP23 by selecting an optimal light index on the basis of nighttime light data; measuring an increase or a decrease of a specific variable over time at a pixel level using trend analysis; and modifying a gravity model that reflects an economic linkage strength between cities. The present disclosure can provide data support and methodological basis for the high-quality economic development of the urban agglomeration.