Patents Assigned to The University
  • Compositions of A-8R peptide
    Patent number: 9393254
    Abstract: The present invention provides materials and methods useful to treat various sGC?1-expressing cancers. Materials include peptides which interfere with sGC?1's pro-survival functions, thereby resulting in apoptosis of sGC?1-expressing cells. In addition, the present invention provides screening assays, diagnostic assays, methods to prognose, methods to treat, and kits.
    Type: Grant
    Filed: October 30, 2013
    Date of Patent: July 19, 2016
    Assignee: The University of Toledo
    Inventors: Lirim Shemshedini, Shao-Yong Chen, Changmeng Cai, Chen-Lin Hsieh
  • Rapid and enhanced activation of microporous coordination polymers by flowing supercritical CO
    Patent number: 9393548
    Abstract: Flowing supercritical CO2 is used to activate metal organic framework materials (MOF). MOFs are activated directly from N,N-dimethylformamide (DMF) thus avoiding exchange with a volatile solvent. Most MCPs display increased surface areas directly after treatment although those with coordinatively unsaturated metal centers benefit from additional heating.
    Type: Grant
    Filed: December 23, 2013
    Date of Patent: July 19, 2016
    Assignee: The Regents Of The University Of Michigan
    Inventors: Adam J. Matzger, Baojian Liu, Antek G. Wong-Foy
  • Surveillance camera terminal
    Patent number: 9398231
    Abstract: A surveillance camera terminal includes an imaging means that outputs a frame image, an imaging visual field control means that changes the imaging visual field of the imaging means in a surveillance area, an object extracting means that extracts an object being imaged by processing the frame image taken by the imaging means, a tracking means that detects a position of the object in the surveillance area based on a position of the object extracted by the object extracting means on the frame image and the imaging visual field of the imaging means, an imaging visual field storage means that stores an imaging visual field, and detection means that detects whether or not the object being tracked by the tracking means has traveled to a position near a handover area for handover of the object to another surveillance camera terminal.
    Type: Grant
    Filed: February 7, 2011
    Date of Patent: July 19, 2016
    Assignees: Omron Corporation, The University of Tokyo
    Inventors: Shinya Yuasa, Junichi Nakano, Takeshi Naito, Shunsuke Kamijo
  • Methods of treating diseases associated with PPAR?
    Patent number: 9393288
    Abstract: The invention relates to methods for modulating PPAR-? activity using relaxin or agonists thereof. The result is wide range of new therapeutic regimens for treating, inhibiting the development of, or otherwise dealing with, a multitude of illnesses and conditions, including small vessel disorders of the brain and those associated with increased blood-brain barrier permeability, cognitive disorders such as Alzheimer's disease, vascular dementia, epilepsy, stroke, CADASIL and migraine.
    Type: Grant
    Filed: March 12, 2013
    Date of Patent: July 19, 2016
    Assignee: The University of Vermont and State Agricultural College
    Inventor: Marilyn J. Cipolla
  • Nanoscale structures on optical fiber for surface enhanced Raman scattering and methods related thereto
    Patent number: 9395304
    Abstract: A nanoscale structure fabricated on a planar end facet of an optic fiber is described, to enable detection of molecules by surface-enhanced Raman scattering. The nanoscale structure may comprise an array of nanopillars. The nanoscale structure may also comprise a non periodic, or random, surface-relief structure. The nanoscale structure may be coated in a metal, comprising, for example, silver, gold, aluminum, iridium, platinum, palladium, copper, or a combination of the same. The nanoscale structure may be fabricated on a planar end facet of an optical fiber by interference lithography.
    Type: Grant
    Filed: May 23, 2013
    Date of Patent: July 19, 2016
    Assignees: Lawrence Livermore National Security, LLC, The Regents of The University of California
    Inventors: Xuan Yang, Tiziana C. Bond, Jerald Britten, Thomas C. Carlson, Nazar Ileri, Cindy Larson, Claire Gu
  • Systems and methods for image and video signal measurement
    Patent number: 9396531
    Abstract: An image/video may be analyzed to determine quality of its attributes, including local, global and pixel colorfulness, sharpness, and contrast to obtain an image quality measure. Invented quality may be obtained for captured images or videos and compared to a database or reference value of quality measures to identify quality of products, component anomalies, and product matches.
    Type: Grant
    Filed: December 22, 2014
    Date of Patent: July 19, 2016
    Assignees: Tufts University, The Board of Regents of The University of Texas System
    Inventors: Karen Panetta, Sos Agaian, Chen Gao
  • Antibiotic and anti-parasitic agents that modulate class II fructose 1,6-bisphosphate aldolase
    Patent number: 9394254
    Abstract: This invention provides a family of compounds that inhibit Class II fructose 1,6-bisphosphate aldolase (FBA), which is implicated in the pathogenic activity of a broad range of bacterial and parasitic agents. The compounds were identified by empirical testing, and provide a basis for further derivatization and optimization of 8-hydroxyquinoline-2-carboxylic acid and related compounds. Crystal structure shows that the compounds don't bind directly to the catalytic site of the enzyme, and so are not defined simply as substrate analogs. Instead, they create a pocket by induced fit, resulting a powerful and specific inhibitory effect on FBA activity.
    Type: Grant
    Filed: May 8, 2014
    Date of Patent: July 19, 2016
    Assignee: The University of Denver and Regis University
    Inventors: Scott Dusan Pegan, Kateri Ahrendt, Glenn C. Capodagli, Bryan Cowen
  • Injectable, Biodegradable Bone Cements and Methods of Making and Using Same
    Publication number: 20160199533
    Abstract: Compositions of, methods of making, and methods of using alkaline earth phosphate bone cements are disclosed.
    Type: Application
    Filed: March 23, 2016
    Publication date: July 14, 2016
    Applicant: The University of Toledo
    Inventors: Sarit B. Bhaduri, Huan Zhou, Anand K. Agarwal, Vijay K. Goel
  • INTENTION DETECTION IN DOMAIN-SPECIFIC INFORMATION
    Publication number: 20160203118
    Abstract: A new information in a language and relating to a subject matter domain is parsed into a constituent set of complete grammatical constructs. In a subset of the complete grammatical constructs, a set of linguistic styles of the language is identified according to a subset of a set of word-style associations related to the language and independent of the subject matter domain. A first weight is assigned to a first linguistic style and a second weight to a second linguistic style from the set of linguistic styles. A first intention information is mapped to the first style using a first style-intention rule, and a second intention information to the second style using a second style-intention rule. A complete grammatical construct in the subset is tagged with the first intention information responsive to a weight associated with the first intention information exceeding an intention selection threshold.
    Type: Application
    Filed: March 16, 2016
    Publication date: July 14, 2016
    Applicants: International Business Machines Corporation, Baylor College of Medicine, The Board of Regents, The University of Texas System
    Inventors: Meenakshi Nagarajan, William Scott Spangler, Benjamin J. Bachman, Lawrence A. Donehower, Olivier Lichtarge, Sam J. Regenbogen, Angela D. Wilkins, Curtis R. Pickering
  • A LASER SYSTEM FOR IMAGING AND MATERIALS ANALYSIS
    Publication number: 20160202180
    Abstract: A THz quantum cascade laser is used to investigate a target by directing a first beam of laser radiation from the laser at the target to thereby produce a second beam of laser radiation by interaction of the first beam with the target. Self-mixing of the first and second beams occurs within the laser and causes variations in a signal such as the operating voltage of the laser. An operating parameter of the laser that affects the interaction of the first beam with, the target is varied. The operating voltage is monitored and processed to determine phase and amplitude changes associated with material properties of the target. Consequently in one embodiment the invention provides for processing the variations in the signal to produce various images of the target.
    Type: Application
    Filed: August 22, 2014
    Publication date: July 14, 2016
    Applicants: The University of Queensland, University of Leeds
    Inventors: Aleksandar D. RAKIC, Paul DEAN, Alexander Giles DAVIS, Dragan INDJIN, Edmund Harold LINFIELD, Stephen James WILSON, Thomas TAIMRE, Karl BERTLING, Yah Leng LIM
  • Injectable, Biodegradable Bone Cements and Methods of Making and Using Same
    Publication number: 20160199532
    Abstract: Compositions of, methods of making, and methods of using alkaline earth phosphate bone cements are disclosed.
    Type: Application
    Filed: March 24, 2016
    Publication date: July 14, 2016
    Applicant: The University of Toledo
    Inventors: Sarit B. Bhaduri, Huan Zhou, Anand K. Agarwal, Vijay K. Goel
  • Crystallographically-oriented carbon nanotubes grown on few-layer graphene films
    Patent number: 9390828
    Abstract: A thermal and electrical conducting apparatus includes a few-layer graphene film having a thickness D where D?1.5 nm and a plurality of carbon nanotubes crystallographically aligned with the few-layer graphene film.
    Type: Grant
    Filed: October 1, 2012
    Date of Patent: July 12, 2016
    Assignee: The University of Kentucky Research Foundation
    Inventors: Douglas Robert Strachan, David Patrick Hunley
  • Collagen D-spacings in fibril bundles
    Patent number: 9390496
    Abstract: Methods and systems for diagnosing a bone disease or other condition related to collagen in a subject are provided. These include providing a bone sample from the subject and determining a quantitative collagen morphology value of the bone sample. A reference value is provided from a non-affected control subject where the reference value is a quantitative collagen morphology value from the same type of bone sample obtained from a population of non-affected control subjects. The quantitative collagen morphology value of the subject's bone sample is compared to the reference value. If the collagen morphology value is altered versus the reference value, the subject is diagnosed as having a collagen related bone disease. The collagen morphology value can include mean fibril spacings and distributions of the fibril spacings taken from a subject's bone sample.
    Type: Grant
    Filed: October 17, 2013
    Date of Patent: July 12, 2016
    Assignees: The Regents Of The University of Michigan, Henry Ford Health System, Colorado State University Research Foundation
    Inventors: Mark M. Banaszak Holl, Gary J. Fisher, Ming Fang, Clifford M. Les, Bradford G. Orr, Elizabeth Goldstein, Anthony Turner
  • Crystallographically-oriented carbon nanotubes grown on few-layer graphene films
    Patent number: 9388513
    Abstract: A thermal and electrical conducting apparatus includes a few-layer graphene film having a thickness D where D?1.5 nm and a plurality of carbon nanotubes crystallographically aligned with the few-layer graphene film.
    Type: Grant
    Filed: June 29, 2012
    Date of Patent: July 12, 2016
    Assignee: The University of Kentucky Research Foundation
    Inventors: Douglas Robert Strachan, David Patrick Hunley
  • Bisphenol derivatives and their use as androgen receptor activity modulators
    Patent number: 9388112
    Abstract: This invention provides bisphenol derivatives having a structure of formula 1. Said compounds are modulators of the androgen receptor activity and are useful in the treatment of various diseases, including prostate cancer, breast cancer, ovarian cancer, endometrial cancer, acne, ovarian cysts, polycystic ovarian disease, age-related macular degeneration, precocious puberty, hirsutism and hair loss.
    Type: Grant
    Filed: January 6, 2011
    Date of Patent: July 12, 2016
    Assignees: The University of British Columbia, Brittish Columbia Cancer Agency Branch
    Inventors: Marianne D. Sadar, Nasrin R. Mawji, Carmen Adriana Banuelos, Raymond J. Andersen, Javier Garcia Fernandez
  • Electrochemical liquid-liquid-solid deposition processes for production of group IV semiconductor materials
    Patent number: 9388498
    Abstract: An electrochemical liquid-liquid-solid (LLS) process that produces unlimited amounts of crystalline semiconductor, such as Ge or Si, from aqueous or polar solutions with tunable nanostructured shapes without any physical or chemical templating agent is presented. Dissolution into, saturation within, and precipitation of the semiconductor from a liquid electrode (e.g., Hg pool) or near an electrode comprising metallic nanoparticles (e.g., In nanoparticles) yields a polycrystalline semiconductor material, as deposited. Such a process can be conducted at conditions, in a single step, and under electrochemical control, while affording control over formation of a variety of material morphologies. Materials formed by such processes are also provided.
    Type: Grant
    Filed: July 20, 2012
    Date of Patent: July 12, 2016
    Assignee: The Regents Of The University Of Michigan
    Inventors: Stephen Maldonado, Azhar Carim
  • Distributed sensor grid, surface, and skin systems and methods
    Patent number: 9389105
    Abstract: The present disclosure provides distributed sensor grid, surface, and skin systems and methods that utilize compressive sampling systems and methods for reading and processing the outputs of sensor arrays (serial and/or parallel) such that increased speed can be achieved. These sensor arrays can be functionalized or sensitized in any desired manner and functions are derived from the outputs, as opposed to individual data points. The sensor arrays can be made in the form of a textile, a fiber optic network, a MEMS network, or a CMOS camera, for example. In general, in accordance with the systems and methods of the present disclosure, a Code is applied to a distributed sensor as part of the compressive sampling technique and derives the functions.
    Type: Grant
    Filed: June 20, 2013
    Date of Patent: July 12, 2016
    Assignee: The University of North Carolina at Charlotte
    Inventors: Faramarz Farahi, Mehrdad Abolbashari
  • Shape data generation method and apparatus
    Patent number: 9390549
    Abstract: A shape data generation method relating to this invention includes: first generating first three-dimensional voxel data that represents a target object by using first tomographic images, in which a first region occupied by the target object is designated, among plural tomographic images; extracting, from the first tomographic images, brightness values of voxels included in the first region; second generating a function for calculating a probability that a voxel is included in the first region by using the extracted brightness values; calculating, for each voxel among voxels in a voxel space that includes the plural tomographic images, a probability by using a brightness value of the voxel and the function; and third generating second three-dimensional voxel data that represents the target object by using the first three-dimensional voxel data and probabilities calculated for the voxels in the voxel space.
    Type: Grant
    Filed: February 24, 2015
    Date of Patent: July 12, 2016
    Assignees: FUJITSU LIMITED, The University of Tokyo
    Inventors: Kohei Hatanaka, Toshiaki Hisada, Seiryo Sugiura, Takumi Washio, Jun-ichi Okada
  • Analyte detection using a needle projection patch
    Patent number: 9387000
    Abstract: Apparatus for use in detecting analytes in a subject, wherein the apparatus includes a number of projections provided on a patch, such that applying the patch to the subject causes at least some of the projections to be inserted into the subject and target one or more analytes and a reagent for detecting the presence or absence of analytes.
    Type: Grant
    Filed: May 22, 2009
    Date of Patent: July 12, 2016
    Assignee: The University of Queensland
    Inventors: Simon Robert Corrie, Mark Anthony Fernance Kendall
  • Device to determine visuo-spatial ability
    Patent number: 9386949
    Abstract: The device (10) disclosed herein assists in the diagnosis and classification of neurodegenerative diseases through the assessment of a subject's visuo-spatial ability. The device (10) has a touch-screen display (11) into which a user can input data utilizing a stylus (13) or the like. A position reader is provided, linked to a position data storage means and also a timer to link a time value to said position data, the time value being stored in a time data storage means. Storage means is also provided for preset-value data relating to known data on medical conditions, with the preset-value data having been produced in accordance with an evolutionary algorithm. A comparator compares the user input data with the preset-value data, and the result is output.
    Type: Grant
    Filed: July 15, 2013
    Date of Patent: July 12, 2016
    Assignee: The University of York
    Inventors: Stephen Smith, Michael Adam Lones