Patents Assigned to The University
  • METHODS AND COMPOSITIONS RELATED TO Th-1 DENDRITIC CELLS
    Publication number: 20160263206
    Abstract: Certain embodiments of the invention are directed to methods for inducing an immunologic response to a tumor in a patient using mature dendritic cells transfected with a nucleic acid composition encoding one or more tumor antigens and loaded with a corresponding tumor antigen composition.
    Type: Application
    Filed: April 19, 2016
    Publication date: September 15, 2016
    Applicant: Board of Regents, The University of Texas System
    Inventors: William K. DECKER, Elizabeth J. SHPALL, Krishna V. KOMANDURI, Dongxia XING
  • Composition
    Patent number: 9439837
    Abstract: The present invention relates to a photosensitive composition comprising synthetic nanocrystalline hydroxyapatite or a synthetic precursor thereof doped with a rare earth ion, the use of the composition in restorative or cosmetic dentistry, a process for preparing the composition and a method of generating an image of an exposed dentinal surface of a tooth.
    Type: Grant
    Filed: October 10, 2011
    Date of Patent: September 13, 2016
    Assignees: University of Leeds, The University Court of the University of St. Andrews
    Inventors: Wilson Sibbett, Christian Thomas Alcuin Brown, Animesh Jha, Steven John Milne, Colin Robinson, Mandeep Singh Duggal, Kyriacos Jack Toumba
  • Nano cancer barrier device (NCBD) to immobilize and inhibit the division of metastic cancer stem cells
    Patent number: 9439941
    Abstract: The present invention provides methods, compositions, and kits wherein nanomaterials are used for inhibiting cancer stem cell division, colony formation, spheroid formation and self-renewal. The present invention also provides methods, compositions, and kits wherein nanomaterials are used for treating cancer, coating tumors, and inhibiting metastasis. The present invention also provides methods, compositions, and kits wherein nanomaterials are used for inducing cells to go into stasis. The present invention further provides methods for isolating tumors, inhibiting bleeding, and marking margins of tumors and organs during surgery with a nanomaterial.
    Type: Grant
    Filed: December 14, 2010
    Date of Patent: September 13, 2016
    Assignee: The University of Hong Kong
    Inventors: Rutledge Ellis-Behnke, Patrick Ming Tat Ling
  • Short-range zigbee compatible receiver with near-threshold digital baseband
    Patent number: 9444515
    Abstract: An 8.1 nJ/bit 2.4 GHz receiver with integrated digital baseband supporting Q-QPSK DSSS modulation compliant with the IEEE 802.15.4 standard is presented that targets short-range, Internet of Things applications (IoTs). The sensitivity of a wireless communication receiver in general trades with power consumption. This receiver exploits this tradeoff to achieve a total power consumption of 2.02 mW including ADCs and digital baseband processing, at a sensitivity of ?52.5 dBm at 250 Kbps. The energy-efficiency of the radio frequency (RF) front-end alone is nearly two times better than the prior art. The receiver was fabricated in 65 nm CMOS with an area of 0.86 mm2.
    Type: Grant
    Filed: April 24, 2015
    Date of Patent: September 13, 2016
    Assignee: The Regents Of The University Of Michigan
    Inventors: Osama U. Khan, David D. Wentzloff
  • Antisense oligonucleotides for inducing exon skipping and methods of use thereof
    Patent number: 9441229
    Abstract: An antisense molecule capable of binding to a selected target site to induce exon skipping in the dystrophin gene, as set forth in SEQ ID NO: 1 to 202.
    Type: Grant
    Filed: September 11, 2015
    Date of Patent: September 13, 2016
    Assignee: The University of Western Australia
    Inventors: Stephen Donald Wilton, Sue Fletcher, Graham McClorey
  • Non-invasive methods for determining cardiac output
    Patent number: 9439577
    Abstract: Cardiac output is measured using a non-invasive method comprised of administering hyperbaric or hypobaric gas to the subject then after a time measuring the resultant changes in central or peripheral oxygen saturation times using a pulse oximeter located at a peripheral body site. Preferably the device is portable and is comprised of a gas cartridge, with one or more doses, and a mouth-piece, a microprocessor for performing the analysis, a pulse oximeter probe and a display for reporting the cardiac output.
    Type: Grant
    Filed: March 13, 2013
    Date of Patent: September 13, 2016
    Assignee: The University of Vermont and State Agricultural College
    Inventor: Markus Meyer
  • Cell line for production of adeno-associated virus
    Patent number: 9441206
    Abstract: This invention relates to a HEK293 cell line that grows under animal component-free suspension conditions. The cell line is ideal for rapid and scalable production of adeno-associated virus (AAV) and supports production of all serotypes and chimera of AAV.
    Type: Grant
    Filed: October 26, 2012
    Date of Patent: September 13, 2016
    Assignee: The University of North Carolina at Chapel Hill
    Inventors: Joshua Grieger, Richard Jude Samulski
  • Multiple-input isolated push-pull connected power converters
    Patent number: 9444358
    Abstract: A multiple-input power converter transferring energy from multiple input sources to a load. The multiple-input power converter utilizes a push-pull converter that isolates loads from sources by a transformer in the output rectifier stage. The isolation increases the safety of the system and provides a wider range of sources-to-load voltage transfer ratios. Furthermore, the multiple-input power converter utilizes a lower number of components in comparison to previously designed multiple-input power converter topologies as well as has a lower control circuit implementation cost when compared to previously designed soft-switching multiple-input power converters.
    Type: Grant
    Filed: August 14, 2013
    Date of Patent: September 13, 2016
    Assignee: Board of Regents, The University of Texas System
    Inventors: Alexis Kwasinski, Sheng-Yang Yu
  • ?-conjugated heavy-metal polymers for organic white-light-emitting diodes
    Patent number: 9444065
    Abstract: A polymer mixture emits a broad spectrum of visible light that appears white or near-white in the aggregate. The polymer mixture comprises two (or more) components in the active layer. A heavy atom, such as platinum and/or iridium, present in the backbone of the mixture acts via a spin-orbit coupling mechanism to cause the ratio of fluorescent to phosphorescent light emission bands to be of approximately equal strength. These two broad emissions overlap, resulting in an emission spectrum that appears to the eye to be white.
    Type: Grant
    Filed: May 14, 2007
    Date of Patent: September 13, 2016
    Assignee: The University of Utah Research Foundation
    Inventors: Zeev Valentine Vardeny, Leonard Wojcik, Tomer Drori
  • Superoleophobic surfaces and methods of making same
    Patent number: 9442375
    Abstract: Disclosed herein is a substrate having a surface modified to impart multi-scale roughness, thereby providing superhydrophobic and/or superoleophobic properties. The surface comprises a pattern of microscale pillars topped by a plurality of nanoparticles having a re-entrant convex shape. The area fraction of the surface is also selected to provide the desired superoleophobic properties. Also disclosed herein is a process for creating the modified surface comprising photolithography, optionally followed by vapor deposition. The substrates may be formed into useful articles or applied to pre-formed articles.
    Type: Grant
    Filed: June 18, 2013
    Date of Patent: September 13, 2016
    Assignees: ARLANXEO Singapore PTE LTD., The University of Western Ontario
    Inventors: Jun Yang, Tingjie Li, Maxim Paliy, Xiaolong Wang, Natalie Suhan
  • Methods and compositions for producing vitamin K dependent proteins
    Patent number: 9441208
    Abstract: The present invention relates to methods and compositions for improving the productivity of recombinant vitamin K dependent protein expression in host cells.
    Type: Grant
    Filed: September 18, 2014
    Date of Patent: September 13, 2016
    Assignee: The University of North Carolina at Chapel Hill
    Inventors: Darrel W. Stafford, Tao Li
  • Turbulence-free camera system and related method of image enhancement
    Patent number: 9444978
    Abstract: A turbulence-free CCD camera system with nonclassical imaging resolution, for applications in long- distance imaging, such as satellite and aircraft-to-ground based distant imaging, utilizing an intensity- fluctuation correlation measurement of thermal light. The proposed camera system has the following advantages over classic imaging technology: (1) it is turbulence-free; (2) its spatial resolution is mainly determined by the angular diameter of the light source. For example, using sun as the light source, this camera may achieve a spatial resolution of 200 micrometer for any object on Earth. 200-micrometer resolution is insignificant for short distance imaging, however, taking a picture of a target at 10-kilometer, a classic camera must have a lens of 90-meter diameter in order to achieve 200-micrometer resolution.
    Type: Grant
    Filed: June 17, 2014
    Date of Patent: September 13, 2016
    Assignee: The University of Maryland, Baltimore County
    Inventors: Yanhua Shih, Hui Chen, Tao Peng
  • YTTRIUM ALUMINUM GARNET BASED THERMAL BARRIER COATINGS
    Publication number: 20160257618
    Abstract: Embodiments of a microstructure that allows arrest of contaminant infiltration includes an inter layer and at least one highly reactive ceramic layer. The inter layer is not reactive to an infiltrating reactive species. The HRC layer includes materials that react with a reactive contaminant species to slow or arrest infiltration of such contaminant species.
    Type: Application
    Filed: February 10, 2016
    Publication date: September 8, 2016
    Applicant: The University of Connecticut
    Inventors: Eric H. Jordan, Maurice Gell, Rishi Kumar, Chen Jiang
  • Machine Tool and Workpiece Machining Method
    Publication number: 20160256977
    Abstract: A machine tool includes a spindle retaining a tool, a spindle motor, a feed device relatively moving a workpiece and a tool with a feed motor, a spindle motor control unit, and a feed motor control unit. The spindle motor control unit continuously varies a rotational speed of the spindle in a periodic or non-periodic manner with a predetermined amplitude with respect to a target rotational speed. The feed motor control unit controls the feed motor in synchronization with the control of the spindle motor to continuously vary a relative moving speed between the tool and the workpiece such that a ratio of the rotational speed of the spindle to the moving speed does not become constant at least in a predetermined time zone in which a spindle speed reaches a maximal value and a predetermined time zone in which the spindle speed reaches a minimal value.
    Type: Application
    Filed: March 3, 2016
    Publication date: September 8, 2016
    Applicants: The University of Tokyo, DMG MORI CO., LTD.
    Inventors: Hiroshi Fujimoto, Satoshi Fukagawa, Shinji Ishii, Yuki Terada
  • Adjustable Height Pedicle Screw
    Publication number: 20160256198
    Abstract: Described herein is a pedicle screw for use in the thoracolumbar spine where the height can be adjusted intra-operatively before or after installation member of the longitudinal member. The pedicle screws with adjustable height may be made with a monoaxial or polyaxial configuration. The height of the pedicle screw can be lengthened or shortened.
    Type: Application
    Filed: February 29, 2016
    Publication date: September 8, 2016
    Applicant: The University of Toledo
    Inventors: Ashok Biyani, Gary Durivage
  • Composition for inducing proliferation or accumulation of regulatory T cells
    Patent number: 9433652
    Abstract: It was found that bacteria belonging to the genus Clostridium induce accumulation of regulatory T cells (Treg cells) in the colon. Moreover, the present inventors found that regulatory T cells (Treg cells) induced by from these bacteria suppressed proliferation of effector T-cells. From these findings, the present inventors found that the use of bacteria belonging to the genus Clostridium or a physiologically active substance derived therefrom made it possible to induce proliferation or accumulation of regulatory T cells (Treg cells), and further to suppress immune functions.
    Type: Grant
    Filed: September 22, 2014
    Date of Patent: September 6, 2016
    Assignee: The University of Tokyo
    Inventors: Kenya Honda, Koji Atarashi, Kikuji Itoh, Takeshi Tanoue
  • Systems and methods for enhanced SCODA
    Patent number: 9434938
    Abstract: Methods and apparatus for separating, concentrating and/or detecting molecules based on differences in binding affinity to a probe are provided. The molecules may be differentially modified. The molecules may be differentially methylated nucleic acids. The methods can be used in fields such as epigenetics or oncology to selectively concentrate or detect the presence of specific biomolecules or differentially modified biomolecules, to provide diagnostics for disorders such as fetal genetic disorders, to detect biomarkers in cancer, organ failure, disease states, infection or the like.
    Type: Grant
    Filed: August 16, 2013
    Date of Patent: September 6, 2016
    Assignee: The University of British Columbia
    Inventors: Andrea Marziali, Joel Pel, Jason Donald Thompson, Gosuke Shibahara
  • Image domain pansharpening method and system for spectral CT with large pixel energy discriminating detectors
    Patent number: 9437016
    Abstract: A hybrid CT dataset is obtained from a combination of a integrating detector and a photon-counting detector. The hybrid CT dataset contains low-resolution photon-counting data and high-resolution integrating data. High-resolution panchromatic images are generated from the high-resolution integrating data, and low-resolution spectral images are generated from the low-resolution photon-counting data. The high-resolution panchromatic images inherit the resolution properties of the integrating detector while the low-resolution spectral images inherit the spectral information of the photon-counting detector. Subsequently, the low resolution spectral images are pansharpened based upon at least one high resolution panchromatic image that lacks spectral information according to a pansharpening algorithm.
    Type: Grant
    Filed: August 7, 2013
    Date of Patent: September 6, 2016
    Assignees: Toshiba Medical Systems Corporation, The University of Chicago
    Inventors: David Rigie, Patrick La Riviere, Adam Petschke
  • Branched siloxanes and methods for synthesis
    Patent number: 9434750
    Abstract: The present invention describes branched and functionalized siloxanes and methods for making such compounds. The compounds have a variety of uses. One preferred application is as novel planarizing material for lithography, in which case functionalized branched siloxane, such as an epoxy-modified branched siloxane is particularly useful.
    Type: Grant
    Filed: April 8, 2015
    Date of Patent: September 6, 2016
    Assignee: Board of Regents, The University of Texas System
    Inventors: C. Grant Willson, Tsuyoshi Ogawa, Michael B. Jacobsson
  • Peach tree named ‘GulfAtlas’
    Patent number: PP27128
    Abstract: A new and distinct variety of peach tree, denominated ‘GulfAtlas’, has a winter chilling requirement estimated at approximately 400 chill units (cu). The tree is medium size, moderately vigorous, and semi-spreading in growth habit. It bears showy, pink flowers, and leaves with reniform glands. Trees of ‘GulfAtlas’ are self-fertile and regularly bear heavy annual crops. Fruit are uniformly firm and have yellow, non-melting flesh. Fruit are nearly round, and uniform with substantially symmetrical shape, and have an attractive approximately 75% red skin. The fruit of ‘GulfAtlas’ typically ripen about 3 weeks after ‘Gulfcrimson’ in midJune at Attapulgus, Ga.
    Type: Grant
    Filed: September 27, 2013
    Date of Patent: September 6, 2016
    Assignees: The United States of America, as represented by the Secretary of Agriculture, The University of Georgia Research Foundation Inc., The University of Florida
    Inventors: Thomas G Beckman, Jose X Chaparro, Patrick J Conner