Abstract: A dental and facial imaging device includes an adjustable arm, an image sensor mounted on a first end of the adjustable arm and an adjustable patient positioning arm mounted on a second end of the adjustable arm. A distance between the adjustable patient positioning arm and the image sensor is adjustable based on an adjustable length of the adjustable arm. A position indicator scale of the adjustable arm includes multiple notches for calibrating the distance between the adjustable patient positioning arm and the image sensor. The adjustable patient positioning arm includes a patient teeth supporting device and a patient chin rest which are positioned at a fixed coordinate reference relative to the image sensor to capture an image of a patient's teeth. The fixed coordinate reference corresponds to co-ordinates of multiple anatomical planes associated with the patient teeth supporting device and a patient chin rest relative to the image sensor.

Abstract: Provided herein is a method of detecting microorganisms in liquid samples using image features, such as time profiles of object light scattering intensity and time profiles of object position. Related methods, devices, systems, and other aspects are also provided.

Abstract: The present invention provides a copolymer, preferably a degradable copolymer, comprising at least first and second repeat units and/or derived from at least first, second, and third monomers.

Abstract: Disclosed herein are methods for using dual amplification of MYC and HSF1 in cancer cells to identify cancer cells having increased susceptibility to a therapeutic inhibitor. Disclosed herein are methods for treating a patient with cancer where the cancer cells have coamplification of MYC and HSF1. Also disclosed are methods for identifying therapeutic target and therapeutic compounds by screening with cells known to have dual amplification of MYC and HSF1.

Abstract: A nasal trans-esophageal echocardiography system includes a nasal trans-esophageal device comprising a sheath defining a lumen therein, the sheath having a width sufficiently narrow to fit through a nasal passage of a subject, an ultrasound probe having a width sufficiently narrow to extend through said lumen defined by said sheath, and a workstation configured to communicate with said ultrasound probe to receive ultrasound signals from said ultrasound probe and to form ultrasound images based on said ultrasound signals.

Abstract: Methods of uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are provided. Kits for uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are also provided. The molecules to be labeled may include, but are not limited to, RNAs, cDNAs, DNAs, proteins, peptides, and/or antigens.

Abstract: Ultra pH sensitive (UPS) micelles encapsulating cytokines are provided that provide lower toxicity and higher efficacy compositions and methods for treating cancer with those compositions.

Abstract: An all-solid-state battery and a method of manufacturing an all solid-state battery are disclosed. The all solid-state battery includes a metal oxide and a metal capable of alloying with lithium, thus uniformly depositing lithium during charging and enabling operation at room temperature (e.g., 20-25° C.).

Abstract: Provided is a high-efficiency expression vector of a circular ribonucleic acid (circRNA). The high-efficiency expression vector is an expression framework with a total length of only 173 bp and having a nucleotide sequence shown in SEQ ID NO: 1, and includes an upstream frame sequence of 92 bp, a downstream frame sequence of 75 bp, and a restriction site EcoR I located between the upstream and downstream frame sequences for inserting a gene to be circularized. In the present disclosure, the high-efficiency expression vector of a circRNA can enable an exogenously-inserted sequence to efficiently express the circRNA, thus providing an efficient expression tool for obtaining the circRNA. On the premise of ensuring efficient circularization of the circRNA, lengths of upstream and downstream flanking sequences required for the circularization have been highly optimized to further reduce the complexity of splicing by-products caused by the flanking sequences.

Abstract: A system and method for end-to-side anastomosis to an anatomical passageway is disclosed. The system and method are particularly useful in coupling an LVAD pump to an aorta. The system and method include using a tubular graft member having a skirt flange that engages the side of the aorta, a seating assembly and a flanged stent for securing the tubular graft to the side of the anatomical passageway. An assembly for creating an opening in the side of the anatomical passageway and an assembly for delivering the tubular graft is also disclosed.

Abstract: The digital human workplace solution is deployed in a customer service setting and involves a computer programmed with a digital human that is displayed to interact with the customer and adapt to inputs providing information about the user or the environment. The digital human workforce solution is also programmed to interface with one or more databases of information that can be used during the customer service interaction.

Abstract: The present disclosure is directed to characterizing the adhesion between thin films and rigid substrates. Exemplary embodiments provide systems, apparatus and methods to characterize mechanical mix-mode adhesion between thin films and rigid substrates using the blister test (BT). Exemplary embodiments provide the full triaxial displacement field obtained through Digital Image Correlation with inverse Finite Element Method simulations using Cohesive Zone Elements. Particular embodiments eliminate the need for making mechanistic or kinematic assumptions of the blister formation and allow the characterization of the full traction-separation law governing the adhesion between the film and the substrate. Exemplary embodiments can aid in the design and optimization of adhesively bonded structures by providing a comprehensive understanding of the adhesion mechanics between thin films and rigid substrates.

Abstract: A method of producing an ultraviolet laser diode with a low oscillation threshold current density includes stacking a first cladding layer, a light-emitting layer, and a second cladding layer on a substrate in this order to form a nitride semiconductor laminate (step S101), etching at least a portion of the nitride semiconductor laminate to form a mesa structure and setting the ratio between the length of the resonator end faces and the length of the side surfaces of the mesa structure in plan view between 1:5 and 1:500 (step S102), disposing first conductive material on a portion of a first area and applying heat treatment of 400° C. or higher to form a first electrode (step S103), and disposing a second conductive material in an area on the second cladding layer, at a distance of 5 ?m or more from the side surfaces, to form a second electrode (step S104).

Abstract: A customized external cranioplasty includes a rigid section and a rim at least one of attached to or integral with the rigid section and extending at least partially around a periphery of the rigid section. The rigid section has a size and shape to substantially match a cranial defect and includes an impact-resistant material to provide protection and support to a user due to the cranial defect. The rim facilitates secure and comfortable contact of the customized external cranioplasty to the user's head. A method of producing a customized external cranioplasty includes receiving three-dimensional imaging data for at least a portion of a subject's skull that has a cranial defect: segmenting the cranial defect region from a surrounding portion of the subject's skull to obtain a surface requiring support by the customized external cranioplasty; and producing a rigid section of the customized external cranioplasty using said surface requiring support obtained from the segmenting.

Abstract: An image-guided robotic spine injection system includes an injection robot registered to an interoperative imaging system for real-time guidance. The system includes a guidance system to communicate with said injection robot and said interoperative imaging system during an injection procedure. The guidance system includes a preoperative injection plan based on preoperative imaging data of a subject's spine, and includes anatomical features identified as preoperative registration markers. The guidance system receives interoperative imaging data from said interoperative imaging system of said subject's spine. The guidance system receives an indication of anatomical features identified as interoperative registration markers that correspond in a one-to-one relationship to each of said preoperative registration markers. The guidance system registers said interoperative registration markers with said preoperative registration markers to transform said preoperative injection plan to an interoperative injection plan.

Abstract: The present invention relates to a deep reinforcement learning-based cloud data center adaptive efficient resource allocation method. First, an operation (a scheduling job) is selected according to a score evaluated by critic (an evaluation operation) by using an actor parameterized policy (resource allocation). Then, a resource allocation policy is updated through gradient boosting, and a variance of a policy gradient is reduced by using an advantage function, to improve training efficiency; and wide simulation experiments are performed by using real data from a Google cloud data center. Compared with two advanced DRL-based cloud resource allocation methods and five classic cloud resource allocation methods, the method provided in the present invention has higher quality of service (QoS) in terms of a delay and a job dropout rate and has higher energy efficiency.

Abstract: Disclosed herein a method for agile simulation of a stochastic computing image processing where the input operands are processed with the aid of a correlation-controlled contingency table (CT) construct without using actual stochastic bit-streams. The disclosed method utilizes contingency tables to perform (i) template matching, (ii) image compositing, and (iii) pattern detection. Results show that the proposed approach achieves similar computation accuracy to the traditional stochastic computing simulation while performing runtime- and memory-efficient computations.

Abstract: A constant-speed dynamic direct-shear test system and a test method for a rock mass structural plane are provided in the disclosure; the system includes a bearing frame, a loading frame, a horizontal loading device, a normal loading device, an oil supply device and a digital controller; a shear box is arranged in the loading frame, and the loading frame is fixedly connected with a top surface of one end of the bearing frame; the oil supply device and the horizontal loading device are controlled by the digital controller and output shearing force, the normal loading device is arranged on the loading frame and provides normal force to the shear box.

Abstract: An ultrasonic-stirring narrow gap welding system and a welding method, and the ultrasonic-stirring narrow gap welding system includes a welding machine power source, a wire feeder, a narrow gap welding torch, and an ultrasonic stirring subsystem. A welding wire is fed into a narrow gap through the narrow gap welding torch provided above a groove, to generate an arc for welding. The ultrasonic stirring subsystem includes a stirrer and an ultrasonic device, a stirring rod is connected to the ultrasonic device and inserted into a molten pool to form a preset angle relative to the welding wire for stirring, and an ultrasonic-stirring narrow gap welding mode is realized.

Abstract: Multiple fluorophores within a sample can be imaged by merging a plurality of beams from different wavelength light sources of excitation light into a single path, directing the excitation light into the sample, and detecting light emitted by the fluorophores within the sample on two different arrays of pixels (e.g., two regions within a single camera sensor chip). The light sources are activated during respective timeslots, and captured image data is processed. For at least one of the timeslots, the processing of the image data comprises using the image data captured using the first array of pixels to detect a presence of a given fluorophore, and using the image data captured using the second array of pixels to detect a presence of a different fluorophore. This arrangement enables a system that includes only N light sources to image more than N fluorophores.