Patents Assigned to The University
  • MINE MANAGEMENT SYSTEM
    Publication number: 20160217535
    Abstract: A mine management system to mine ore in a mine including a mining area, a first mine shaft, and a second mine shaft connecting the mining area and the first mine shaft, the mine management system includes: a transporting machine loading the ore mined in the mining area and transporting the ore to a soil discharge area while traveling in the first mine shaft; a loading machine staying in the second mine shaft while a space for the transporting machine to travel therein is left inside the first mine shaft, excavating the ore in the mining area, conveying the mined ore from the mining area in an opposite direction, and loading the mined ore on the transporting machine; and a management device determining a mining area in which the loading machine is disposed based on a difference between a production plan and an actual production amount of the mine.
    Type: Application
    Filed: September 30, 2014
    Publication date: July 28, 2016
    Applicants: Komatsu Ltd., The University of Tokyo
    Inventors: Yuichi Kodama, Masaaki Uetake, Kazunari Kawai, Shinichi Terada, Rui Fukui
  • REDUCED PARAMETER SPACE KINETIC MODELING SYSTEMS AND METHODS
    Publication number: 20160216246
    Abstract: Systems, methods and devices are provided for fitting kinetic models to measurements of dynamic curves where the kinetic models give rise to nonlinear fitting equations in two or more unknowns that can be formulated so that they are linear in one or more of the unknown parameters and nonlinear in one or more of the unknown parameters. Such systems, methods and devices may be utilized to monitor and characterize the attributes of a given tracer such as a radioactive substance within a body, a drug within the body, a concentration of a substance within a particular medium, and the like.
    Type: Application
    Filed: June 5, 2012
    Publication date: July 28, 2016
    Applicant: The University of Utah Research Foundation
    Inventors: Dan J. Kadrmas, Mehmet Bugrahan Oktay
  • LIMIT SIZE LIPID NANOPARTICLES AND RELATED METHODS
    Publication number: 20160214103
    Abstract: Limit size lipid nanoparticles, methods for using the lipid nanoparticles, and methods and systems for making limit size lipid nanoparticles.
    Type: Application
    Filed: March 31, 2016
    Publication date: July 28, 2016
    Applicant: The University of British Columbia
    Inventors: Pieter R. Cullis, Igor V. Jigaltsev, James R. Taylor, Timothy Leaver, Andre Wild, Nathan Maurice Belliveau
  • Radiographic phantom apparatuses
    Patent number: 9398889
    Abstract: There is provided a radiographic phantom for inter alia mimicking specific anatomical parts in a computerized tomography scan. Methods are provided for a variety of purposes including detecting a difference between a measured optical deformation of a radiographic phantom pair and a theoretical deformation of the radiographic phantom pair.
    Type: Grant
    Filed: November 11, 2013
    Date of Patent: July 26, 2016
    Assignee: The Regents Of The University Of California
    Inventors: Neil Kirby, Cynthia Chuang, Jean Pouliot
  • Treatments for migraine and related disorders
    Patent number: 9399053
    Abstract: Embodiments are directed to compositions and methods of treating migraine and related neurological disorders. In certain aspects, methods and compositions are for reducing cortical spreading depression and/or suppressing the neurochemical basis for chronic and acute migraine events, and provide methods and pharmaceutical compositions related to both acute and preventive therapies for migraine events and related headaches. In particular embodiments, treatment involves IL-11, interferon-gamma, or an IGF inducer such as IGF-1 or insulin.
    Type: Grant
    Filed: July 20, 2012
    Date of Patent: July 26, 2016
    Assignee: The University of Chicago
    Inventors: Richard Kraig, Aya Pusic, Heidi Mitchell, Yelena Grinberg, Marcia Kraig
  • Thin film deposition apparatus and thin film deposition method using electric field
    Patent number: 9399826
    Abstract: A thin film deposition apparatus and a thin film deposition method using an electric field are provided. The thin film deposition apparatus includes: a first substrate; a plurality of electrodes in a 2D arrangement on the first substrate; and a solution provided on the plurality of electrodes and in which charged nanoparticles are distributed, wherein the charged nanoparticles are selectively deposited on at least a part of the plurality of electrodes by independently applying a voltage to each of the plurality of electrodes.
    Type: Grant
    Filed: May 15, 2014
    Date of Patent: July 26, 2016
    Assignees: SAMSUNG ELECTRONICS CO., LTD., The Regents of The University of California
    Inventors: Jin S. Heo, Hwi-yeol Park, Kyung-hoon Cho, Kyoung-hwan Choi, Se-jung Kim, Michael J. Heller, Young-jun Song
  • Concurrent chemotherapy and immunotherapy
    Patent number: 9399662
    Abstract: The concurrent administration of chemotherapy and immunotherapy has been considered a contraindication because of the concern that the induced lymphopenia would ablate therapeutic efficacy of immunotherapy. Temozolomide has been shown to be an effective chemotherapeutic for patients with malignant gliomas and to deprive patients with glioblastoma (GBM) patients of this agent in order to treat with immunotherapy is controversial. Despite conventional dogma, we demonstrate that both chemotherapy and immunotherapy can be delivered concurrently without negating the effects of immunotherapy, hi fact, the temozolomide induced lymphopenia may actually be synergistic with a peptide vaccine.
    Type: Grant
    Filed: November 2, 2006
    Date of Patent: July 26, 2016
    Assignees: Duke University, Board of Regents, The University of Texas System
    Inventors: John H. Sampson, Darell D. Bigner, Duane Mitchell, Amy Heimberger
  • Synthetic route to pactamycin and pactamycin analogs
    Patent number: 9399652
    Abstract: Methods and intermediates useful for making compounds of Formula (I) are described, including a general method of making an alpha, beta-diamino ketone by reacting an imine with a 2-amino-substituted 1,3-dicarbonyl in a Mannich addition reaction to produce said alpha,beta-diamino ketone.
    Type: Grant
    Filed: January 23, 2014
    Date of Patent: July 26, 2016
    Assignee: The University of North Carolina at Chapel Hill
    Inventors: Jeffrey Johnson, Justin Malinowski, Robert Sharpe
  • Methods, systems, and computer readable media for synthesizing sounds using estimated material parameters
    Patent number: 9401684
    Abstract: The subject matter described herein includes methods, systems, and computer readable media for synthesizing sounds using estimated material parameters. According to one aspect, a method for sound synthesis using estimated material parameters is provided. The method includes at a computing platform including a memory and a processor, estimating, by the processor and based on a recorded audio sample of an impact on a physical object, one or more material parameters of a physical object for use in synthesizing a sound associated with a virtual object having material properties similar to the physical object. The method further includes storing the one or more material parameters in memory. The method further includes using the estimated material parameters to generate a synthesize sound for the virtual object.
    Type: Grant
    Filed: May 31, 2013
    Date of Patent: July 26, 2016
    Assignee: The University of North Carolina at Chapel Hill
    Inventors: Zhimin Ren, Hengchin Yeh, Ming Lin
  • IMMUNOTHERAPY
    Publication number: 20160206726
    Abstract: The invention provides an agent comprising: a cyclic peptide comprising a T cell antigen peptide; wherein in cyclised form the T cell antigen peptide is not capable of eliciting a T cell response; and wherein the T cell antigen peptide is rendered capable of eliciting a T cell response by selective cleavage of one or more cleavage sites in the cyclic peptide. The agent may be used to prevent or treat a condition characterised by the presence of unwanted cells.
    Type: Application
    Filed: December 31, 2015
    Publication date: July 21, 2016
    Applicant: The University of Birmingham
    Inventors: Mark Cobbold, David Millar
  • Materials and Methods for Modulating DISC1 Turnover
    Publication number: 20160206679
    Abstract: The invention relates to the finding that turnover of DISC1 (Disrupted in schizophrenia 1) is mediated by the F-box-containing protein FBXW7 (F-box/WD repeat-containing protein 7). The sequence within DISC1 that binds to FBXW7 and targets DISC1 for turnover by the ubiquitin-proteasome system is identified. The invention provides antagonists that inhibit this interaction and methods of using these antagonists to decrease DISC1 turnover, for example in treatment of neuropsychiatric disorders, as well as methods of identifying new antagonists.
    Type: Application
    Filed: September 29, 2014
    Publication date: July 21, 2016
    Applicant: The University Court of the University of Glasgow
    Inventor: George BAILLIE
  • Fabrication of Iridium Oxide pH Sensors and Sensory Arrays
    Publication number: 20160209348
    Abstract: A method of fabricating amorphous iridium oxide film pH sensors and microfluidic devices incorporating the pH sensors. The present invention provides a fabrication method for sol-gel based iridium oxide (IrOx) thin film pH sensors and microelectrodes. The invention further provides microelectrode arrays produced by the fabrication methods and microfluidic devices including the microelectrodes and microelectrode arrays. In one aspect, the invention is a method for fabricating a microelectrode pH sensor.
    Type: Application
    Filed: September 22, 2014
    Publication date: July 21, 2016
    Applicant: Board of Regents, The University of Texas System
    Inventors: Jung-Chih Chiao, Cuong M. Nguyen, Smitha MN Rao
  • Use of RhoA in Cancer Diagnosis and Inhibitor Screening
    Publication number: 20160208335
    Abstract: Disclosed are a novel method of detecting cancer, a method of screening inhibitors and anticancer agents that target cancer-related molecules, RHOA polypeptide having mutation and a polynucleotide encoding the polypeptide as a therapeutic agent for cancer, and a method of detecting cancer using the polypeptide or polynucleotide. Also disclosed are a vector and a host cell comprising the polynucleotide, a method of screening therapeutic agents for cancer comprising the polypeptide and/or the polynucleotide, and a therapeutic agent for cancer comprising siRNA having a silencing effect on RHOA mutant.
    Type: Application
    Filed: September 4, 2014
    Publication date: July 21, 2016
    Applicants: The University of Tokyo, Chugai Seiyaku Kabushiki Kaisha
    Inventors: Hiroyuki ABURATANI, Shumpei ISHIKAWA, Miwako KAKIUCHI, Takashi NISHIZAWA
  • Methods of treating diseases associated with PPAR?
    Patent number: 9393288
    Abstract: The invention relates to methods for modulating PPAR-? activity using relaxin or agonists thereof. The result is wide range of new therapeutic regimens for treating, inhibiting the development of, or otherwise dealing with, a multitude of illnesses and conditions, including small vessel disorders of the brain and those associated with increased blood-brain barrier permeability, cognitive disorders such as Alzheimer's disease, vascular dementia, epilepsy, stroke, CADASIL and migraine.
    Type: Grant
    Filed: March 12, 2013
    Date of Patent: July 19, 2016
    Assignee: The University of Vermont and State Agricultural College
    Inventor: Marilyn J. Cipolla
  • Aural proxies and directionally-varying reverberation for interactive sound propagation in virtual environments
    Patent number: 9398393
    Abstract: The subject matter described herein includes a method for simulating directional sound reverberation. The method includes performing ray tracing from a listener position in a scene to surface as visible from a listener position. The method further includes determining a directional local visibility representing a distance from a listener position to nearer surface in the scene alone each ray. The method further includes determining directional reverberation at the listener position based on the directional local visibility. The method further includes rendering a simulated sound indicative of the directional reverberation at the listener position.
    Type: Grant
    Filed: November 15, 2013
    Date of Patent: July 19, 2016
    Assignee: The University of North Carolina at Chapel Hill
    Inventors: Lakulish Shailesh Antani, Dinesh Manocha
  • Antibiotic and anti-parasitic agents that modulate class II fructose 1,6-bisphosphate aldolase
    Patent number: 9394254
    Abstract: This invention provides a family of compounds that inhibit Class II fructose 1,6-bisphosphate aldolase (FBA), which is implicated in the pathogenic activity of a broad range of bacterial and parasitic agents. The compounds were identified by empirical testing, and provide a basis for further derivatization and optimization of 8-hydroxyquinoline-2-carboxylic acid and related compounds. Crystal structure shows that the compounds don't bind directly to the catalytic site of the enzyme, and so are not defined simply as substrate analogs. Instead, they create a pocket by induced fit, resulting a powerful and specific inhibitory effect on FBA activity.
    Type: Grant
    Filed: May 8, 2014
    Date of Patent: July 19, 2016
    Assignee: The University of Denver and Regis University
    Inventors: Scott Dusan Pegan, Kateri Ahrendt, Glenn C. Capodagli, Bryan Cowen
  • Systems and methods for image and video signal measurement
    Patent number: 9396531
    Abstract: An image/video may be analyzed to determine quality of its attributes, including local, global and pixel colorfulness, sharpness, and contrast to obtain an image quality measure. Invented quality may be obtained for captured images or videos and compared to a database or reference value of quality measures to identify quality of products, component anomalies, and product matches.
    Type: Grant
    Filed: December 22, 2014
    Date of Patent: July 19, 2016
    Assignees: Tufts University, The Board of Regents of The University of Texas System
    Inventors: Karen Panetta, Sos Agaian, Chen Gao
  • Compositions of A-8R peptide
    Patent number: 9393254
    Abstract: The present invention provides materials and methods useful to treat various sGC?1-expressing cancers. Materials include peptides which interfere with sGC?1's pro-survival functions, thereby resulting in apoptosis of sGC?1-expressing cells. In addition, the present invention provides screening assays, diagnostic assays, methods to prognose, methods to treat, and kits.
    Type: Grant
    Filed: October 30, 2013
    Date of Patent: July 19, 2016
    Assignee: The University of Toledo
    Inventors: Lirim Shemshedini, Shao-Yong Chen, Changmeng Cai, Chen-Lin Hsieh
  • Surveillance camera terminal
    Patent number: 9398231
    Abstract: A surveillance camera terminal includes an imaging means that outputs a frame image, an imaging visual field control means that changes the imaging visual field of the imaging means in a surveillance area, an object extracting means that extracts an object being imaged by processing the frame image taken by the imaging means, a tracking means that detects a position of the object in the surveillance area based on a position of the object extracted by the object extracting means on the frame image and the imaging visual field of the imaging means, an imaging visual field storage means that stores an imaging visual field, and detection means that detects whether or not the object being tracked by the tracking means has traveled to a position near a handover area for handover of the object to another surveillance camera terminal.
    Type: Grant
    Filed: February 7, 2011
    Date of Patent: July 19, 2016
    Assignees: Omron Corporation, The University of Tokyo
    Inventors: Shinya Yuasa, Junichi Nakano, Takeshi Naito, Shunsuke Kamijo
  • Rapid and enhanced activation of microporous coordination polymers by flowing supercritical CO
    Patent number: 9393548
    Abstract: Flowing supercritical CO2 is used to activate metal organic framework materials (MOF). MOFs are activated directly from N,N-dimethylformamide (DMF) thus avoiding exchange with a volatile solvent. Most MCPs display increased surface areas directly after treatment although those with coordinatively unsaturated metal centers benefit from additional heating.
    Type: Grant
    Filed: December 23, 2013
    Date of Patent: July 19, 2016
    Assignee: The Regents Of The University Of Michigan
    Inventors: Adam J. Matzger, Baojian Liu, Antek G. Wong-Foy