Patents Assigned to The University
  • Patent number: 12186397
    Abstract: A cell tissue gel, comprising one or more matrix molecules cross-linked with a cross-linking agent, and a quenching agent bound to a reactive group of the cross-linking agent, wherein the quenching agent contains a moiety that is capable of reacting with the reactive group of the cross-linking agent and the one or more matrix molecules contain one or more functional groups that are capable of cross-linking with the reactive group, the amount of the reactive group of the cross-linking agent being equal to or less than a total amount including the amount of the one or more functional groups and the amount of the moiety.
    Type: Grant
    Filed: October 29, 2018
    Date of Patent: January 7, 2025
    Assignee: National Cheng Kung University
    Inventor: Lynn L. H. Huang
  • Patent number: 12186735
    Abstract: A polymer/activated carbon composite made up of a branched polyethylenimine and magnetic cores involving Fe3O4 disposed activated carbon. The magnetic cores have activated carbonyl groups on the surface. A process for removing organic dyes, such as methyl red, as well as heavy metal ions from a polluted aqueous solution or an industrial wastewater utilizing the composite is introduced. A method of synthesizing the polymer/activated carbon composites is also specified.
    Type: Grant
    Filed: August 19, 2024
    Date of Patent: January 7, 2025
    Assignee: King Fahd University of Petroleum and Minerals
    Inventors: Tawfik Abdo Saleh Awadh, Akram Abdulhakeem Al-Absi
  • Patent number: 12191414
    Abstract: Compositions of matter, downconversion layers including the compositions of matter, and devices including the compositions of matter are described. In an embodiment, the compositions of matter are downconversion materials configured to absorb a quantum of energy of a first energy and, in response, emit two or more quanta of energy of a second energy less than the first energy. Methods of making and depositing downconversion materials are also described. Downconversion precursor mixtures suitable for making downconversion materials and methods of making the same are also described.
    Type: Grant
    Filed: April 26, 2019
    Date of Patent: January 7, 2025
    Assignee: UNIVERSITY OF WASHINGTON
    Inventors: Daniel R. Gamelin, Daniel M. Kroupa, Tyler J. Milstein, Sidney E. Creutz, Matthew J. Crane, Joo Yeon Roh
  • Patent number: 12186381
    Abstract: The invention pertains to the use of VirB10 to immunize a host against an infection by a bacterium having T4SS. The invention provides a vaccine comprising VirB10, a fragment of VirB10, a polynucleotide encoding VirB10 or a polynucleotide encoding a fragment of VirB10 and a pharmaceutically acceptable carrier and/or adjuvant. The invention also provides a method of immunizing a host against an infection caused by a bacterium having T4SS, the method comprising administering to the host a vaccine of the invention. The vaccines and the methods of the invention can be used to immunize against infections caused by bacteria having T4SS in dogs, rabbits, cats, pigs, cattle, sheep, goats, deer, horses, rodents and humans.
    Type: Grant
    Filed: January 6, 2021
    Date of Patent: January 7, 2025
    Assignee: UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED
    Inventors: Anthony F. Barbet, Francy L. Crosby
  • Patent number: 12192455
    Abstract: The present invention provides an image encoding method and an image decoding method. The image decoding method, according to the present invention, comprises the steps of: decoding information associated with a clipping range of a current block; and performing sample adaptive offset (SAO) filtering on the basis of the information associated with the clipping range, wherein the information associated with the clipping range may include information on the maximum and minimum values of a pixel value included in the current block.
    Type: Grant
    Filed: August 24, 2023
    Date of Patent: January 7, 2025
    Assignee: Industry Academy Cooperation Foundation of Sejong University
    Inventors: Joo Hee Moon, Dong Jae Won, Sung Won Lim
  • Patent number: 12187670
    Abstract: Oxidizing a first aromatic compound in the presence of a metal salt to yield a second aromatic compound includes combining the first aromatic compound, the metal salt, and water to yield an aqueous mixture, and heating the aqueous mixture at a temperature exceeding 200° C. to yield a reaction product that includes the second aromatic compound.
    Type: Grant
    Filed: January 25, 2021
    Date of Patent: January 7, 2025
    Assignee: Arizona Board of Regents on behalf of Arizona State University
    Inventors: Grant Loescher, Everett Shock, Ian Gould, Hilairy Hartnett, Lynda B. Williams
  • Patent number: 12191143
    Abstract: A plasma enhanced chemical vapor deposition (PECVD) method includes loading a wafer having a magnetic layer thereon into a processing chamber equipped with a radio frequency (RF) system, introducing an aromatic hydrocarbon precursor into the processing chamber, and turning on an RF source of the RF system to decompose the aromatic hydrocarbon precursor into active radicals at a frequency greater than about 1000 Hz to form a graphene layer over the magnetic layer.
    Type: Grant
    Filed: May 6, 2021
    Date of Patent: January 7, 2025
    Assignees: TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, LTD., NATIONAL TAIWAN UNIVERSITY
    Inventors: Jian-Zhi Huang, Yun-Hsuan Hsu, I-Chih Ni, Chih-I Wu
  • Patent number: 12189263
    Abstract: A photonic Mach Zehnder Interferometer (MZI) has a first arm with a first photonic waveguide transmitting a first light having a first phase, a second arm with a second photonic waveguide transmitting a second light having a second phase, and a Transparent Conducting Oxide (TCO) based assembly. The TCO assembly is positioned about the first photonic waveguide of the first arm to modulate the first phase of the first light traveling in the first photonic waveguide.
    Type: Grant
    Filed: February 25, 2022
    Date of Patent: January 7, 2025
    Assignee: The George Washington University
    Inventors: Rubab Amin, Volker J. Sorger
  • Patent number: 12186590
    Abstract: The invention provides methods of treating metastatic or unresectable pancreatic cancer through the administration of a combination of an immune modulator and radiation therapy.
    Type: Grant
    Filed: October 18, 2019
    Date of Patent: January 7, 2025
    Assignee: UNIVERSITY OF ROCHESTER
    Inventors: Scott Andrew Gerber, Dominick Auci
  • Patent number: 12188150
    Abstract: A method for clonal-growth of a single-crystal metal, including: using copper as an example, placing an existing small-sized single-crystal copper foil with a plane of any index on a copper foil that needs to be single-crystallized, and performing annealing to obtain, by cloning, a large-area (in meters) single-crystal copper foil with the same surface index as that of the parent facet. The method solves the difficult problem of large-area single-crystal copper foil preparation. By performing annealing, a parent single-crystal copper foil with a very small size (˜0.25 cm2) can be cloned to produce a large-area (˜700 cm2) single-crystal copper foil, which is an increase in area of about 3000 times.
    Type: Grant
    Filed: June 4, 2019
    Date of Patent: January 7, 2025
    Assignee: PEKING UNIVERSITY
    Inventors: Kaihui Liu, Zhibin Zhang, Muhong Wu, Dapeng Yu, Enge Wang
  • Patent number: 12191633
    Abstract: An optical integrated light source includes a plurality of topological ring resonators. Each of the topological ring resonators is defined by an interface between two distinct periodic structures having different topological invariants such that a one-way edge mode may be excited along the interface. A magnetic material is arranged to interact with the plurality of topological ring resonators such that the optical integrated light source is structured and configured to generate plural beams each carrying large orbital angular momentum.
    Type: Grant
    Filed: March 25, 2020
    Date of Patent: January 7, 2025
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Boubacar Kante, Babak Bahari
  • Patent number: 12187787
    Abstract: The present invention relates to in a monoclonal antibody produced by CpG-DNA, or a functional fragment thereof, the monoclonal antibody, or functional fragment thereof, characterized in that it comprises polypeptide sequence selected from the group consisting of the following polypeptide sequences a heavy chain comprising a complementarity determining region 1 (CDR 1) amino acid sequence consisting of the sequence of SEQ ID NO: 1, a CDR2 consisting of the sequence of SEQ ID NO: 2 and a CDR 3 consisting of the sequence of SEQ ID NO: 3; and a light chain comprising CDR1 amino acid sequence consisting of the sequence of SEQ ID NO: 4, a CDR2 consisting of the sequence of SEQ ID NO: 5 and a CDR 3 consisting of the sequence of SEQ ID NO: 6 and a use of the same.
    Type: Grant
    Filed: February 26, 2019
    Date of Patent: January 7, 2025
    Assignee: INDUSTRY ACADEMIC COOPERATION FOUNDATION, HALLYM UNIVERSITY
    Inventors: Hyung Joo Kwon, Te Ha Kim, Dong Bum Kim
  • Patent number: 12187629
    Abstract: A system of treating reject brine and capturing carbon dioxide (CO2) includes a two-stage electrodialysis (ED) process for producing multiple products with high purity from rejected brine and flue gas mixtures (10% CO2 and 90% N2) emitted from an industrial plant. According to an embodiment, the system includes a first electrodialysis (ED) stage and a second electrodialysis (ED) stage in series.
    Type: Grant
    Filed: May 24, 2023
    Date of Patent: January 7, 2025
    Assignee: UNITED ARAB EMIRATES UNIVERSITY
    Inventors: Jawad Mustafa, Ali H. Al-Marzouqi, Nayef Mohamed Ghasem
  • Patent number: 12187875
    Abstract: A polystyrene-based chalcone including units of a 1-(2H-1,3-benzodioxol-5-yl)-3-[4-(dimethylamino)phenyl]-(2E)-propane-1-one and units of a 2-hydroxyethyl methacrylate. The units of the 1-(2H-1,3-benzodioxol-5-yl)-3-[4-(dimethylamino)phenyl]-(2E)-propane-1-one and the units of the 2-hydroxyethyl methacrylate are in a matrix of a polystyrene. A process for preparing the polystyrene-based chalcone and application as a laser medium with fine coating characteristics.
    Type: Grant
    Filed: July 8, 2024
    Date of Patent: January 7, 2025
    Assignee: IMAM MOHAMMAD IBN SAUD ISLAMIC UNIVERSITY
    Inventors: Khalid Hassan Ibnouf Ahmed, Hajo Idriss Mohammed Idriss, Osamah Abdulrahman Aldaghri, Amin Osman Elzupir Alamalhuda
  • Patent number: 12190483
    Abstract: A method for visualization of dynamic objects using a generative manifold includes steps of: acquiring a set of measurements associated with the dynamic objects using sensors; estimating parameters of a generator using the set of measurements and estimating latent variables using the set of measurements; modeling using a computing device the dynamic objects as a smooth non-linear function of the latent variables using the generator such that points in a latent subspace are mapped to a manifold in a generative manifold model; and generating a visualization of the dynamic objects using the generative manifold model. The set of measurements may include multi-slice data. The generative manifold model may provide for modeling deformations.
    Type: Grant
    Filed: January 11, 2022
    Date of Patent: January 7, 2025
    Assignee: UNIVERSITY OF IOWA RESEARCH FOUNDATION
    Inventors: Mathews Jacob, Qing Zou
  • Patent number: 12188338
    Abstract: A microwave drill bit capable of achieving fracturing of a borehole wall and end of a deep hard rock while drilling and a use method thereof are provided. The microwave drill bit comprises a microwave drill bit body, wherein a support frame front plate, a metal sleeve and a water inlet ring sequentially sleeve on the microwave drill bit body, the metal sleeve is connected with a rotary drive I mounted on the support frame front plate, the microwave drill body is connected with a microwave mode converter and a microwave splitter II respectively, the microwave mode converter and the microwave splitter II are connected with a microwave splitter I by a rectangular waveguide, the microwave splitter I is sequentially connected with a microwave rotating joint, a fixed waveguide and a microwave generator, and the microwave rotating joint is connected with a rotary drive II mounted on the support frame rear plate.
    Type: Grant
    Filed: April 21, 2023
    Date of Patent: January 7, 2025
    Assignee: NORTHEASTERN UNIVERSITY
    Inventors: Feng Lin, Xiating Feng, Chengxiang Yang, Jiuyu Zhang, Shiping Li, Tianyang Tong, Xiangxin Su
  • Patent number: 12191150
    Abstract: A switching includes a gallium nitride semiconductor and a gate insulation film. The gate insulation film is made of silicon oxide and disposed above the gallium nitride semiconductor layer. An interface between the gallium nitride insulation film and the gate insulation film is either free of a gallium oxide layer or provided with the gallium oxide layer with a thickness of 1 nanometer or smaller.
    Type: Grant
    Filed: February 2, 2022
    Date of Patent: January 7, 2025
    Assignees: DENSO CORPORATION, TOYOTA JIDOSHA KABUSHIKI KAISHA, MIRISE Technologies Corporation, Kochi Prefectural Public University Corporation
    Inventors: Hidemoto Tomita, Takashi Okawa, Toshiyuki Kawaharamura, Li Liu
  • Patent number: 12187809
    Abstract: The invention relates to proximity-based sortase-mediated protein purification and ligation. Specifically, the invention relates to techniques that links protein expression/purification with conjugation to therapeutic agents, imaging agents, or linkers.
    Type: Grant
    Filed: January 28, 2022
    Date of Patent: January 7, 2025
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Andrew Tsourkas, Burcin Altun, Hejia Henry Wang, Feifan Yu
  • Patent number: 12187992
    Abstract: The present disclosure provides a device for assessing adhesion strength of a cancer cell and methods of using the same.
    Type: Grant
    Filed: February 19, 2021
    Date of Patent: January 7, 2025
    Assignee: The Regents of the University of California
    Inventors: Adam Engler, Afsheen Banisadr, Pranjali Beri, Alexander Fuhrmann
  • Patent number: 12188946
    Abstract: Methods, devices, kits and computer-implemented methods for diagnosing (and optionally treating) tuberculous meningitis (TBM) are provided. In one embodiment, the method comprises testing a cerebrospinal fluid (CSF) sample from a subject suspected of having TBM for the presence of MPO and at least two other biomarkers, at least one of the other biomarkers being selected from the group consisting of IFN-?, sICAM-1, VEGF-A and CXCL8. For example, the method can comprise testing the sample for MPO, IFN-? and VEGF-A or for MPO, IFN-?, sICAM-1 and CXCL8. In another embodiment, the method comprises testing a blood sample from a subject suspected of having TBM for the presence of at least one biomarker selected from the group consisting of adipsin (complement factor D), Ab42 and IL-10, and at least two other biomarkers. In one example, the method comprises testing the sample for the presence of adipsin (complement factor D), Ab42 and EL-10.
    Type: Grant
    Filed: May 23, 2019
    Date of Patent: January 7, 2025
    Assignee: STELLENBOSCH UNIVERSITY
    Inventors: Novel Njweipi Chegou, Regan Shane Solomons, Gerhard Walzl, Masilo Charles Manyelo