Abstract: A method for detecting an unsaturated compound, the method comprising monitoring change in electrical properties of a substance that reacts or interacts with unsaturated compounds.

Abstract: The present invention relates to methods and uses of FcRL4 expression and optionally RANKL expressing B cells as biomarkers and therapeutic target for treatment of an autoimmune and/or chronic diseases associated with joint inflammation, in particular Rheumatoid Arthritis (RA).

Abstract: The present disclosure relates to biofragment compositions that comprise bioparticle fragments and at least one heterologous antigen-binding molecule. In some embodiments, the biofragment is typically derived from a larger, intact bioparticle that express the at least one heterologous antigen-binding molecule at the surface, and the biofragment has increased solubility to facilitate assays for antigen detection. The disclosure also relates the related methods of using and making the biofragment compositions, as well as systems and devices implementing the biofragment compositions. In some embodiments, the related methods, systems and devices do not require additional detection reagents, such as animal derived detection antibodies.

Abstract: The present invention relates to a medium for storing, preserving, culturing, and/or differentiating stem cells. The medium employs a synthetic thermo-responsive copolymer, dispersed in an aqueous vehicle, which allows the medium to be readily “switched” between a non-gelatinous (fluid) form and a gelatinous form by simply adjusting temperature across the gelling temperature of the medium. As such, stem cells can be easily captured within a 3D gel matrix by simply mixing the stem cells with the non-gelatinous/fluid form of the medium and then gelling the medium by adjusting the temperature across the gelling temperature of the medium. The stem cells encapsulated within the gelatinous form of the medium may then be preserved for a significant time period before either using the stem cells directly within the medium (e.g. in therapy, or in culturing, differentiation, and such like), or after their extraction from the medium.

Abstract: Based on heart behavior data, a computation unit determines a first time step at which a heart exhibits a first behavior in response to a first wave of an electrical signal, as well as a second time step at which the heart exhibits a second behavior in response to a second wave of the same. The computation unit reproduces the heart's behavior over time by updating a three-dimensional model of the heart according to the heart behavior data, simultaneously with variations in electrical signal strength over time according to electrocardiogram data. The computation unit coordinates this reproduction such that a first shape of the heart at the first time is reproduced step simultaneously with the first wave of the electrical signal, and such that a second shape of the heart at the second time step is reproduced simultaneously with the second wave of the electrical signal.

Abstract: Described herein is a method and system for vehicle localization in an open pit mining environment having intermittent or incomplete GPS coverage. The system comprises GPS receivers associated with the vehicles and providing GPS measurements when available, as well as one or more cameras 50,55 overlooking the mine region 10. The cameras 50,55 are at a known location and are used for generating a sequence of images in a field of view with predetermined calibration in a fixed coordinate system. The system further comprises a vehicle recognition processor 120 for analyzing individual images from the camera to identify and locate within an image a vehicle in the mine region, as well as a vehicle tracking processor 130 for analyzing a sequence of images from the camera to track the identified vehicle location in the sequence of images.

Abstract: An MgB2 superconducting wire excellent in critical current density property is supplied by using a crystalline boron powder which is low in costs and easy to obtain. For the wire, a precursor of the MgB2 superconducting wire is used, the precursor having a linear structure including a core region containing a magnesium powder and a boron powder, and a sheath region formed of a metal covering an outer circumferential portion of the core region. The boron powder is crystalline, and has a volume-mean particle size of 2 ?m or less.

Abstract: A method of extending a user interface to include additional data fields is provided. A first response is received at a first application. The first response indicates a selection of an add button associated with addition of a data field to a first window associated with a user interface of a second application. A second window is presented to a user of the first application. A second response is received at the first application. The second response includes a name for the data field entered by the user using the presented second window and a data type of the data field. A position of the data field is identified on the first window. The received name, the received data type, and the identified position for the data field are stored. The data field is presented in the first window at the stored position using the stored name when a second user executes the second application.

Abstract: The present invention relates to a biocompatible material and in particular to a two-phase or composite biocompatible ceramic material, wherein the first phase is a doped calcium zinc silicate and the second phase is a metal oxide. In an embodiment, the invention has been developed for use in tissue regeneration including bone tissue. In other embodiments, the invention has been developed as a coating to improve the long-term stability of prior art implantable medical devices.

Abstract: The present invention provides peptides and methods of their use in treating bone disorders and bone-related conditions and in treating obesity.

Abstract: Disclosed herein is an automatic fluid dispensing method and system for dispensing fluid on the surface of a plate-like material, or substrate, including a semiconductor wafer for imprint lithography processes. The dispensing method uses fluid dispenser and a substrate stage that may generate relative lateral motions between a fluid dispenser tip a substrate. Also described herein are methods and devices for creating a planar surface on a substrate using a substantially unpatterned planar template.

Abstract: A charging control system that controls charging of an automobile that uses electric power as motive power include a receiving unit that receives electric power demands from an electric power supplier side; and a control unit that controls charging on and off of the automobile. The control unit changes a ratio of a charging-on duration and a charging-off duration in each duration in allowable charging durations for the automobile according to changes of the electric power demands over time.

Abstract: A photonic crystal-metallic (PCM) structure receives an input light signal from a light source. The PCM structure includes a metal structure and a photonic crystal structure disposed adjacent the metal structure. The photonic crystal structure is configured to receive the input light signal such that the input light signal excites surface plasmons of the metallic structure and such that the input light signal is internally reflected within the photonic crystal structure.

Abstract: Disclosed are vaccines and vaccine adjuvants useful in the treatment and/or prevention of infection and diseases associated with infectious pathogens, such as tetanus, as well as diseases associated with biological toxins. Also provided are methods of preparing an adjuvant and the vaccine containing the adjuvant. Methods are also provided for vaccinating/immunizing an animal against infection and diseases associated with infectious pathogens, such as tetanus, and other diseases associated with biological toxins. Adjuvant materials are presented that are prepared from an extracellular matrix material. The adjuvant may also be described as a heterologous acellular collagenous tissue preparation. The adjuvants are demonstrated to enhance the immunogencity of an infectious pathogen antigen or biological toxin antigen of interest, as well as to enhance the survival of an immunized animal.

Abstract: A method of coating a material onto projections provided on a patch. The method includes applying a coating solution containing the material to at least the projections and drying the coating solution to at least the projections using a gas flow.

Abstract: The present invention relates to methods for removing antigens from tissues by sequentially destabilizing and/or depolymerizing cytoskeletal components and removing and/or reducing water-soluble antigens and lipid-soluble antigens. The invention further relates to tissue scaffolding and decellularized extracellular matrix produced by such methods.

Abstract: Compounds having a structure of Formula I and compositions comprising these compounds are provided. Uses of such compounds and compositions are provided for treatment or prophylaxis of viral infection. In particular, compounds and compositions may be for use in the treatment or prophylaxis of viral influenza.

Abstract: According to one embodiment, a microprobe includes a supporting base, an insulating layer, and an electrode layer arrayed in a first direction in this order. A principal surface of the microprobe is formed in a second direction different from the first direction. A step is formed on at least the electrode layer on the principal surface, and the electrode layer is partitioned into a first area and a second area by the step.

Abstract: The invention relates to frozen dessert compositions and methods of preparation thereof. In particular, the invention is relates to a method for preparing a frozen dessert composition, such as ice cream, fortified with vegetables and/or fruits and soybeans, such as edamame or dried mature soybeans and the resulting enriched frozen dessert compositions having a fine texture, good and creamy mouth-feel and tastes with different flavors.

Abstract: A novel class of saturated or conjugated dendrimers containing at least one strong ?-donating group coordinated to cyclometalated tridentate gold(III) compounds having the chemical structure depicted by generic formula: wherein: (a) [Au] is a cyclometalated tridentate gold(III) group; (b) Unit A is a ?-donating chemical group; (c) Unit B is a central part of the dendrons comprising a branch point of component dendrimers; (d) Unit C is optional surface groups or dendrons of the dendrimers; (e) n=0 or 1.