Patents Assigned to The University
  • Method of actuation using knit-constrained pneumatics
    Patent number: 11519432
    Abstract: A pneumatic textile system capable of transforming from a two-dimensional structure to a three-dimensional structure under pneumatic pressure is provided. The pneumatic textile system includes a seamless knit fabric having a grid configuration defining a plurality of grid areas—a first of the plurality of grid areas having a tensile strength that is different from a second of the plurality of grid areas. A pneumatic bladder member is disposed along at least a portion of a boundary between adjacent ones of the plurality of grid areas and is inflatable to exert a force on the seamless knit fabric, wherein upon inflation of the pneumatic bladder member the force is exerted on the seamless knit fabric such that the first of the plurality of grid area assumes a shape different than the second of the plurality of grid areas resulting in a three-dimensional structure transformation.
    Type: Grant
    Filed: January 9, 2018
    Date of Patent: December 6, 2022
    Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: Wei-Chang Adam Wang, Sean Ahlquist
  • System and method for artificial intelligence story generation allowing content introduction
    Patent number: 11520971
    Abstract: Techniques for artificial intelligence assisted story generation includes training a neural network with first training data that indicates text for one or more portions of a training story and second training data that indicates text for a subset of text for an immediately following portion and third training data that indicates full text for the same portion. First data is retrieved that indicates text for a first one or more portions of a different new story. Second data is also received that indicates text for a cued subset of a next portion of the new story. Third data is generated that indicates full text for the next portion of the new story based on the first data and the second data and the neural network. The third data is concatenated to the first data to produce output data that is stored.
    Type: Grant
    Filed: March 30, 2020
    Date of Patent: December 6, 2022
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Snigdha Chaturvedi, Faeze Brahman, Alexandru Petrusca
  • Crystal-free wireless devices
    Patent number: 11522566
    Abstract: A crystal-free wireless device includes a frequency calibration module and a local radio frequency (RF) oscillator having a first frequency and configured to communicate with the frequency calibration module. The crystal-free wireless device also includes a relaxation ring oscillator configured to communicate with the frequency calibration module. The relaxation ring oscillator is further configured to receive a calibration signal or periodic radio frequency packets from a wireless network and provide a reference signal to the frequency calibration module. The relaxation ring oscillator is a crystal-free oscillator. The frequency calibration module is configured to generate a calibration signal that is fed back through a Frequency Locked Loop (FLL) to the local RF oscillator to calibrate the local RF oscillator. The calibrated local RF oscillator is configured to generate a clock signal.
    Type: Grant
    Filed: May 17, 2019
    Date of Patent: December 6, 2022
    Assignee: The Regents of the University of California
    Inventors: Kristofer Pister, Osama Ullah Khan, Bradley Wheeler
  • Selective, adsorbate-induced spin state changes in transition metal-based metal-organic frameworks
    Patent number: 11517878
    Abstract: An adsorbate-selective metal organic framework includes a transition metal; and a plurality of organic molecules coordinated to the transition metal so as to preserve open coordination sites for selectively adsorbing molecules that have low-lying ?* orbitals. The transition metal has a lowest energy spin state in the presence of the selectively adsorbed molecules that are strongly bonding to the transition metal through ?-donating interactions which is different than the lowest energy spin state in the absence of these adsorbed molecules. The transition metal has also a lowest energy spin state in the presence of non-selected molecules that are weakly bonding to the transition metal through ?- and/or ?-accepting and/or donating interactions.
    Type: Grant
    Filed: March 31, 2017
    Date of Patent: December 6, 2022
    Assignee: The Regents of the University of California
    Inventors: Jeffrey R. Long, Benjamin K. Keitz, Douglas Reed
  • Compounds and methods for treating nematode infections
    Patent number: 11517568
    Abstract: The present application relates to the treatment of nematode infections.
    Type: Grant
    Filed: September 11, 2020
    Date of Patent: December 6, 2022
    Assignee: The Governing Council of The University of Toronto
    Inventors: Peter Roy, Sean Harrington, Jacob Pyche, Andrew Burns, Rachel Ross, Mark Lautens
  • Therapeutic anti-IgE antibodies and methods and compositions thereof
    Patent number: 11518818
    Abstract: Disclosed herein are anti-IgE antibodies having low binding affinity to human IgE and compositions and methods thereof. In some embodiments, the present invention provides a composition comprising one or more humanized low affinity anti-IgE antibodies (hLAAIGEs) and a pharmaceutically acceptable carrier. In some embodiments, the present invention provides a method of treating a subject for an IgE-mediated disorder, which comprises administering to the subject one or more hLAAIGEs or a composition thereof. In some embodiments, the IgE-mediated disorder is an allergic reaction.
    Type: Grant
    Filed: January 5, 2018
    Date of Patent: December 6, 2022
    Assignees: The Regents of the University of California, Sixal, Inc.
    Inventors: Andrew Saxon, Ke Zhang
  • Magnetic resonance fingerprinting thermometry
    Patent number: 11519987
    Abstract: A method for temperature quantification using magnetic resonance fingerprinting (MRF) includes acquiring MRF data from a region of interest in a subject using an MRF pulse sequence with smoothly varying RF phase for MR resonant frequencies that is played out continuously. For each of a plurality of time intervals during acquisition of the MRF data the method further includes comparing a set of the MRF data associated with the time interval to an MRF dictionary to determine at least one quantitative parameter of the acquired MRF data, determining a temperature change based on the at least one quantitative parameter and generating a quantitative map of the temperature change in the region of interest. The region of interest can include aqueous and adipose tissue.
    Type: Grant
    Filed: April 5, 2021
    Date of Patent: December 6, 2022
    Assignees: Case Western Reserve University, The Regents of the University of Colorado, Government of the United States, As Represented by the Secretary of Commerce
    Inventors: Kathryn Keenan, Megan Poorman, Rasim Boyacioglu, Mark A. Griswold
  • Mutations that drive VH4 antibody autoreactivity
    Patent number: 11518800
    Abstract: Antibodies exhibiting a specific genetically modified signature associated with certain diseases of the central nervous system, like multiple sclerosis (MS) and clinically isolated syndrome have been identified. These antibodies recognize and bind with certain tissues in the brain and central nervous system and thus are useful as therapeutics, in the production of animal disease models, targets for therapies and as part of assays of the central nervous system.
    Type: Grant
    Filed: January 31, 2017
    Date of Patent: December 6, 2022
    Assignee: The Board of Regents of The University of Texas System
    Inventor: Nancy Monson
  • Selective adsorption of gaseous alkenes into non-porous copper(I) complexes: controlling heat of adsorption and loading pressure
    Patent number: 11517877
    Abstract: Disclosed are air-stable small-molecule adsorbents trimeric [Cu—Br]3 and [Cu—H]3 that undergo a reversible solid-state molecular rearrangements to [Cu—Br.(alkene)]2 and [Cu—H.(alkene)]2 dimers. The reversible solid-state rearrangement allows one to break adsorbent design trade-offs and achieve low heat of adsorption while retaining high selectivity and uptake.
    Type: Grant
    Filed: June 23, 2021
    Date of Patent: December 6, 2022
    Assignees: Board of Regents, The University of Texas System, University of Canterbury
    Inventors: Rasika Dias, Matthew Greig Cowan, Devaborniny Parasar
  • Expansion of field of view
    Patent number: 11520169
    Abstract: An implementation of an optical system for expanding the field of view can include a first optical element and a second optical element. The first optical element can include a first surface and a second surface. The first surface can be configured to reflect a first light beam incident on the first surface at a first incident angle greater than a first predetermined angle, and the second surface can be configured to reflect the reflected first light beam towards a location. The second optical element can include a third surface and a fourth surface. The third surface can be configured to reflect a second light beam incident on the third surface at a second incident angle greater than a second predetermined angle, and the fourth surface can be configured to reflect the reflected second light beam towards the location. Related apparatus, systems, techniques and articles are also described.
    Type: Grant
    Filed: October 11, 2018
    Date of Patent: December 6, 2022
    Assignees: THE SCHEPENS EYE RESEARCH INSTITUTE, INC., THE UNIVERSITY OF MURCIA
    Inventors: Eliezer Peli, Fernando Vargas-Martin
  • Multi-use endoscope with integrated device-patient monitoring and patient-provider positioning and disassociation system
    Patent number: 11517205
    Abstract: A system having a scope with a longitudinal length extending between a proximal end and a distal end includes a plurality of markers spaced along the longitudinal length. The system also includes a disassociation and positioning device that is configured to enhance unsedated transnasal endoscopic procedures by at least partially occluding the vision of a patient while enabling body cavity access, and optionally record and sense body functions such as temperature, heart rate and oxygenation of the blood stream. The system further includes a sensor integrated into the distraction device, wherein the sensor is configured to detect the markers on the longitudinal length of the scope.
    Type: Grant
    Filed: May 10, 2022
    Date of Patent: December 6, 2022
    Assignee: The Regents of the University of Colorado, A Body Corporate
    Inventors: Joel Friedlander, Jeremy Prager, Emily Deboer, Robin Deterding
  • Action detection by exploiting motion in receptive fields
    Patent number: 11521044
    Abstract: Techniques regarding action detection based on motion in receptive fields of a neural network model are provided. For example, one or more embodiments described herein can comprise a system, which can comprise a memory that can store computer executable components. The system can also comprise a processor, operably coupled to the memory, and that can execute the computer executable components stored in the memory. The computer executable components can comprise a motion component that can extract a motion vector from a plurality of adaptive receptive fields in a deformable convolution layer of a neural network model. The computer executable components can also comprise an action detection component that can generate a spatio-temporal feature by concatenating the motion vector with a spatial feature extracted from the deformable convolution layer.
    Type: Grant
    Filed: May 17, 2018
    Date of Patent: December 6, 2022
    Assignees: INTERNATIONAL BUSINESS MACHINES CORPORATION, THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS
    Inventors: Khoi-Nguyen C. Mac, Raymond Alexander Yeh, Dhiraj Joshi, Minh N. Do, Rogerio Feris, Jinjun Xiong
  • Restoring physiology in iron-deficient organisms using small molecules
    Patent number: 11517540
    Abstract: Provided are methods of treating a disease or condition characterized by a deficiency of or a defect in an iron transporter using a small molecule. For example, the method may increase transepithelial iron transport, or it may increase iron release. Additionally, the small molecule may be hinokitiol, or it may be selected from the group consisting of amphotericin B, calcimycin, nonactin, deferiprone, purpurogallin, and maltol. Also provided is a method of identifying a compound capable of treating a disease or condition characterized by a deficiency of or a defect in an iron transporter.
    Type: Grant
    Filed: January 11, 2016
    Date of Patent: December 6, 2022
    Assignee: The Board of Trustees of the University of Illinois
    Inventors: Martin D. Burke, Anthony S. Grillo
  • Encapsulated flexible electronics for long-term implantation
    Patent number: 11517238
    Abstract: Provided are methods of making a long-term implantable electronic device, and related implantable devices, including by providing a substrate having a first encapsulation layer that covers at least a portion of the substrate, the first encapsulation layer having a receiving surface; providing one or more electronic devices on the first encapsulation layer receiving surface; and removing at least a portion of the substrate from the first encapsulation layer; thereby making the long-term implantable electronic device. Further desirable properties, including device lifetime increases during use in environments that are challenging for sensitive electronic device components, are achieved through the use of additional layers such as longevity-extending layers and/or ion-barrier layers in combination with an encapsulation layer.
    Type: Grant
    Filed: October 17, 2018
    Date of Patent: December 6, 2022
    Assignees: NORTHWESTERN UNIVERSITY, THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS
    Inventors: John A. Rogers, Hui Fang, Jianing Zhao, Enming Song, Yoon Kyeung Lee
  • Method for screening for cancer therapeutic agent
    Patent number: 11519901
    Abstract: The invention aims to provide a method of screening for a therapeutic drug for cancer as a molecular-targeted drug targeting some protein from a number of candidate target proteins, without identifying the true target protein. In particular, the invention provides a method of screening for a therapeutic drug for cancer, including (i) a step of expressing an exogenous cell regulatory factor in a target cancer cell under contact or no contact with a test substance, (ii) a step of confirming change in the cancer cell, and (iii) a step of selecting the test substance as a therapeutic drug for cancer when the change of cancer cell increased under contact with the test substance as compared to no contact therewith.
    Type: Grant
    Filed: April 1, 2016
    Date of Patent: December 6, 2022
    Assignee: THE UNIVERSITY OF TOKYO
    Inventors: Yasuhiro Yamada, Katsunori Semi, Knut Woltjen, Yutaka Matsuda
  • IDENTIFICATION OF SPLICING-DERIVED ANTIGENS FOR TREATING CANCER
    Publication number: 20220380937
    Abstract: Methods and processes to identify neoplastic tissue antigens derived from alternative splicing (AS) are described, in accordance with various embodiments of the invention. Also described are novel tumor antigens that are useful as targets in various immunotherapeutic approaches to treating brain cancer as well as novel engineered T cell Receptors (TCRs) and chimeric antigen receptors (CARs) that target these antigenic peptides.
    Type: Application
    Filed: November 6, 2020
    Publication date: December 1, 2022
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Yi XING, Robert PRINS, Yang PAN, Alexander H. LEE
  • NANOCOMPOSITE PARTICLES COMPRISING A BORONIC ACID MOIETY AND METHODS FOR PRODUCING AND USING THE SAME
    Publication number: 20220381789
    Abstract: The present invention provides compositions and methods for determining a saccharide level in a sample. In particular, compositions and methods of the invention include a boronic acid moiety that forms a complex with a saccharide.
    Type: Application
    Filed: May 10, 2021
    Publication date: December 1, 2022
    Applicant: Arizona Board of Regents on Behalf of the University of Arizona, a body corporate
    Inventors: Craig A. Aspinwall, Zeinab Mohktari, Jon T. Njardarson, Colleen M. Janczak, Kevin Scott
  • TARGETING NONSENSE-MEDIATED DECAY TO ACTIVATE P53 PATHWAY FOR THE TREATMENT OF CANCER
    Publication number: 20220380765
    Abstract: The present disclosure provides methods of treating cancer in a patient determined to have a p53 mutation by administering an inhibitor of nonsense mediated decay. The patient may be further administered an inhibitor of mRNA splicing and/or an inhibitor of MDM.
    Type: Application
    Filed: November 2, 2020
    Publication date: December 1, 2022
    Applicant: Board of Regents, The University of Texas System
    Inventors: John V. HEYMACH, Jayanthi GUDIKOTE, Tina CASCONE
  • Device for treating overactive bladder
    Patent number: D972135
    Type: Grant
    Filed: January 5, 2021
    Date of Patent: December 6, 2022
    Assignee: The Regents of the University of California
    Inventor: Gamal Ghoniem
  • Grapevine plant named ‘Clarion’
    Patent number: PP34794
    Abstract: The invention is a new and distinct variety of grapevine plant named ‘Clarion’ that is characterized by its grapes with a moderate juice total acidity (average of 7.73 g/L) making it suitable for wine production, its grapes that lack less desirable aromatic compounds that are typical of cold climate hybrid grapes, its grapes with floral notes including lilac and tropical fruit notes, its good growth habit without excessive vigor, and its grapes with a loose cluster architecture.
    Type: Grant
    Filed: February 2, 2022
    Date of Patent: December 6, 2022
    Assignee: REGENTS OF THE UNIVERSITY OF MINNESOTA
    Inventors: Matthew D. Clark, James Luby, Peter Hemstad