Abstract: Systems and methods for decoding intended symbols from neural activity in accordance with embodiments of the invention are illustrated. One embodiment includes a symbol decoding system for brain-computer interfacing, including a neural signal recorder implanted into a brain of a user, and a symbol decoder, the symbol decoder including a processor, and a memory, where the memory includes a symbol decoding application capable of directing the processor to obtain neural signal data from the neural signal recorder, estimate a symbol from the neural signal data using a symbol model, and perform a command associated with the symbol.

Abstract: A method of manufacturing an interconnect packaging structure is provided. In one aspect, the method includes forming a first body defining a cavity around at least one integrated circuit using an additive manufacturing machine, depositing a conductive transmission line on the first body and electrically coupling the conductive transmission line and the at least one integrated circuit with a conductive interconnect.

Abstract: A transparent photovoltaic cell is provided. The transparent photovoltaic cell includes a first visibly transparent electrode, a visibly transparent active layer including a light absorbing material that has a bandgap greater than or equal to about 2.75 eV, and a second visibly transparent electrode. The active layer is disposed between the first transparent electrode and the second transparent electrode. The transparent photovoltaic cell is visibly transparent.

Abstract: Methods of infecting a mosquito with Wolbachia and controlling a mosquito population with the Wolbachia-infected mosquito are provided herein. The method includes microinjecting a suspension including Wolbachia cells and buffer into a target mosquito embryo to produce a Wolbachia-infected G0 female. The suspension including Wolbachia cells and buffer is obtained by homogenizing a donor insect embryo, tissue, and/or whole body infected with Wolbachia to form a homogenate and the Wolbachia cells are separated from the homogenate.

Abstract: Ultra-wideband (UWB) arrays that are fully planar are provided. Fully-planar inverted-L element (FILE) arrays that are tightly coupled arrays (TCAs) can realize UWB tightly coupled apertures in the W and higher millimeter wave (mmWave) bands. The unit cell architecture of the FILE array, (which can have any desired size, can be comprised of an inverted-L shaped antenna and a capacitively coupled via-fence.

Abstract: A quantitative gait modification and/or analysis system employs instrumented footwear, legwear, and an independent processing module. The instrumented footwear and/or legwear can have sensors that permit the extraction of gait kinematics in real time and provide feedback from it. Embodiments employing calibration-based estimation of kinematic gait parameters are described. An artificial neural network identifies gait stance phases in real-time and selective feedback is provided that targets certain portions of a subject's gait.

Abstract: An internal combustion engine includes a camshaft operably adjusted by a phaser. Another aspect includes an internal combustion engine having an actuation system for an air valve. A further aspect provides a camshaft-in-camshaft system with a cam phaser located adjacent opposite ends. In another aspect, an internal combustion engine apparatus includes multiple nested camshafts with one of the camshafts having a cam configured to actuate an air intake valve associated with a turbulent jet ignition prechamber, and another of the camshafts having a cam configured to actuate an air valve of a main piston combustion chamber, the nested camshafts being independently rotatable by separate electromagnetic actuators.

Abstract: Prediction of allograft rejection is provided based on the quantification of transplant-derived circulating cell-free DNA (dd-cfDNA levels) in the absence of a donor genotype. The technology provided herein alleviates some of the barriers to the implementation of Genome Transplant Dynamics (GTD), which will further widen its clinical application.

Abstract: Nanoparticles comprising a platinum group metal and a base metal, catalytic compositions comprising such nanoparticles and a support material, and methods of making such nanoparticles and catalytic compositions are disclosed. Catalytic articles and exhaust gas treatment systems, as well as methods of treating an exhaust gas stream comprising a pollutant using these catalytic articles and exhaust gas treatment systems, are also disclosed.

Abstract: Provided herein are compositions including brain-capillary binding and/or blood-brain barrier crossing (BBB) tissue-targeting peptides linked thereto or inserted in a targeting protein of a recombinant vector having at least one exogenous peptide comprising an amino acid sequence of Y-G/A/R/K-Y/H-GNPA-T/R/H-RYFD-V/K. Compositions providing such conjugates, targeting peptides, or recombinant vectors having a mutant capsid or envelope protein are provided as are uses thereof.

Abstract: A medical device for retrieval of kidney stone fragments from a urinary tract is provided. The medical device has a plurality of magnets arranged within a flexible sheath forming a flexible wire. The magnets are magnetically attached end-to-end and arranged with their magnetic polarities alternating in direction. The magnetization direction of each of the magnets is orthogonal to the length axis of the flexible wire. A removable inner stylet is situated within the flexible sheath allowing for modifiable flexibility of the wire. The medical device is dimensioned to be introduced into the urinary tract and standard endoscopic devices. The medical device is further dimensioned to allow for the wire with magnetically attached stone fragments to be retrieved from the urinary tract. The magnetic field along the length axis is sufficient to attract to the surface of the flexible wire superparamagnetic nanoparticles which have bound themselves to kidney stone fragments.

Abstract: Multi-band, microstrip patch antennas, as well as methods of fabricating the same and methods of using the same, are provided. A decoupling technique can be used where strategically etched slots are provided between the tightly coupled microstrip patch antennas, and the appropriate mode excitation of the corresponding patch antennas can be used. The antennas have high isolation between the frequency bands of operation. Multi-band operation can be achieved by exciting a different mode on each contiguous portion of the patch antenna.

Abstract: Systems and methods for treatment of neurological conditions using aTBS in accordance with embodiments of the invention are illustrated. One embodiment includes a method for treating neurological conditions, including generating a personalized accelerated theta burst stimulation (aTBS) target representing a location in a patient's brain related to a neurological condition, placing a TMS device relative to the patient's brain such that the focus of the magnetic field is over the aTBS target, applying TMS to the aTBS target according to an aTBS protocol to the brain using the TMS device to alleviate the neurological condition.

Abstract: A dispersion-engineered 2D optical phased array device includes optical slow light waveguides [202, 208, 218] arranged parallel to each other; waveguide bends [206, 216] optically coupling ends of adjacent waveguides of the optical slow light waveguides to form a serpentine optical configuration; wherein the optical slow light waveguides comprise first waveguides of a first waveguide type and second waveguides of a second waveguide type, wherein the first waveguides and the second waveguides are arranged adjacent to each other and alternate with each other; wherein the optical slow light waveguides comprise phased array sections forming a phased array [214], wherein first waveguides and second waveguides have dispersion slopes of opposite sign and the same group index; wherein the optical slow light waveguides comprise slow light delay waveguide sections [210] that provide a delay between adjacent waveguides.

Abstract: A coupled storage qubit nanomechanical resonator in a processing qubit superconducting circuit is provided that includes a phononic crystal resonator (PCR) film disposed on a substrate, where the PCR film includes a defect mode in a bandgap of the PCR film where a storage qubit is encoded, a pair of electrodes generate voltages within the PCR film, where the defect is dimensioned to support a unique electrical potential generated by a local mechanical phonon mode of the PCR film, where a unique resonance frequency that is dependent on the defect dimensions is output from the PCR film, a coupling capacitor that is coupled to the PCR film, where the coupling capacitor is disposed to receive the output unique resonance frequency, and a processing qubit, where the processing qubit is capacitively coupled to the PCR film by the coupling capacitor, where the storage qubits are connected to the processing qubits.

Abstract: Provided herein are heterocyclic derivative compounds and pharmaceutical compositions comprising said compounds that are useful for the treatment of retinal binding protein (RBP4) related diseases, such as obesity and the like.

Abstract: An optical modulator with a wide aperture, high acceptance angle, low required drive voltages and high operating frequency is provided. The modulator relies on the photoelastic effect and makes use of mechanical resonance in order to improve efficiency. The acoustic excitation and optical propagation path are nominally co-aligned, so the required symmetry breaking is provided by having the modulator material be optically and/or mechanically anisotropic. Such a modulator can be used to enable efficient and low-cost per-pixel optical ranging and speed sensing.

Abstract: One or more embodiments relate to an electrically conductive polymer with a crosslinkable additive. The electrically conductive polymer is a directly photopatternable Poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate) PEDOT:PSS film with cross-linked network made of a plurality of monomers. The directly photopatternable PEDOT:PSS film PEDOT as such has a better conductivity and stretchability compared to its other counterparts. The directly photopatternable PEDOT:PSS film can further be supplemented with poly(ethylene glycol) diacrylate (PEGDA) which can help with the removal of PSS. Advantageously, the PEGDA supplemented PEDOT:PSS film can exhibit a larger charge storage capacity.

Abstract: Host cells that are engineered to produce benzylisoquinoline alkaloid (BIAS) precursors, such as norcoclaurine (NC) and norlaudanosoline (NL), are provided. The host cells may have one or more engineered modifications selected from: a feedback inhibition alleviating mutation in a enzyme gene; a transcriptional modulation modification of a biosynthetic enzyme gene; an inactivating mutation in an enzyme; and a heterologous coding sequence. Also provided are methods of producing a BIA of interest or a precursor thereof using the host cells and compositions, e.g., kits, systems etc., that find use in methods of the invention.

Abstract: A delivery system for a transcatheter heart valve (THV) to a subject is provided, the delivery system includes a delivery catheter housing the THV therein; an elongated member for receiving the THV thereon and having an accessory extending from the distal portion thereof, the accessory comprising a plurality of components for alignment with commissures of the THV during delivery of the THV, and a rotational member connected to the elongated member to rotate the accessory and THV together to align with a native or bioprosthetic valve commissure or valve leaflet at a desired angle.