Abstract: A method for determining an insertion trajectory of a tool for reaching a moving target object prior to its insertion into a tissular matrix. The method comprises acquiring images of the tissular matrix, constructing a three-dimensional representation of the tissular matrix, determining coordinates of the initial position of the target object and any obstacles, and determining at least one potential trajectory of the tool from the coordinates of any obstacles and the initial position of the target object. The method further comprises simulating insertion of the tool in the tissular matrix to determine displacement of the target object during insertion of the tool up to the initial position of the target object along a potential trajectory, determining a new position of the target object based on the determined displacement, and determining the insertion trajectory for the new position of the target object.

Abstract: A method for employing certain cobalt complexes as electron donors and in combination with an electron acceptor is provided for preparing an active layer in a photovoltaic conversion cell, as well as to the photovoltaic conversion cell in which the electron donor of the active layer includes such cobalt complexes.

Abstract: A straight, branched or cross-linked polymer, including, per 100 mol %: a) a mole fraction from 75% to 99.95% of monomer units from an N,N-dialkyl acrylamide; b) a mole fraction from 0.05% to 1% of monomer units from a monomer of formula (I): CH2=C(Ri)-C(=0)-0-[(CH2-CH(R2)-0]n-R3 (I); c) optionally a mole fraction higher than 0% to 24% either of monomer units from a monomer including a free strong acid function, partially or totally salified, or of monomer units from a monomer of formula (II): CH2=C(R4)-C(=0)-Y-(CH2)m-N(R5)(R6) (II); d) optionally a mole fraction higher than 0% to 1% of a diethylene or polyethylene cross-linking monomer. Also, a method for treating a surface made of a hydrophobic material, using the polymer, and an aqueous, hydro-organic or organic solution including the polymer for modifying interactions between the species contained the solution and the hydrophobic surface.

Abstract: A method and a system is provided for configuring a device for correcting the effect of a medium on a light signal having propagated through the medium, the device including at least one optical element whose phase profiles are individually adjustable. The configuring system and method include propagating a reference signal and a disordered signal obtained at the output of the medium through the correcting device. An interference parameter is measured and optimized by modifying the phase profile of each of the optical elements of the correcting device. A method and a system is also provided for correcting the effect of a medium on a light signal having propagated through the medium.

Abstract: A new dual biomarker of neurodegeneration and of neuroregeneration

Abstract: The invention relates to a method of making a theremorevsible bituminous composition. The method includes transferring an additive to a bitumen to form a mixture, and stirring the mixture until its appearance is homogenous. The additive can be an organogelator with general formula R?—(COOH)z, where R? is a linear or branched, saturated or unsaturated chain having 4 to 68 carbon atoms and z is an integer varying from 2 to 4. The bituminous composition is hard at the temperature of use without increasing its viscosity when hot.

Abstract: The application provides products, which may trigger pro-apoptotic or pro-death effects on neoplastic cells and/or tissues of the human nervous system, more particularly on neoplastic cells and/or tissues of the human CNS. The products of the application can be used as anti-proliferative or tumoricid agents in the treatment and/or palliation and/or prevention of neoplasms of the human nervous system, more particularly of glioblastoma or brain stem glioma. Therefore, the application also relates to compositions, such as pharmaceutical compositions or drugs, which comprise at least one of said products, as well as to the biotechnological and medical applications of said products and compositions.

Abstract: A computer receives asynchronous information originating from a light sensor (10) having a pixel matrix disposed opposite a scene. The asynchronous information comprises, for each pixel of the matrix, successive events originating from this pixel and depending on variations in light in the scene. For a place of estimation (p) in the matrix of pixels and an estimation time (t), the computer selects a set (Sp t) of events originating from pixels included in a spatial neighborhood (??) of the place of estimation and which have occurred in a time interval (?) defined with respect to the estimation time, such that this set has at most one event per pixel of the spatial neighborhood. The computer quantifies the variations in the times of occurrence of the events of the set selected as a function of the positions, in the matrix, of the pixels from which these events originate.

Abstract: A biocompatible carbon based electrode, and its preparation process are described. The electrode is formed by first and second biocompatible chemically oxygen terminated or H-terminated carbon-based materials. The first material is configured to promote the growth or at least the direct interfacing of adult neurons on the first material without substantially promoting the growth and direct interfacing of glial cells on the first material. The second material presents a peptide coating to promote the growth and at least the direct interfacing of adult glial cells.

Abstract: The present invention relates to a soluble peptide comprising the amino acids sequence: KRFYVVMWKK (SEQ ID NO: 1) or a function-conservative variant thereof for use in the treatment of cancer. The invention also relates to a pharmaceutical composition for use in the treatment of cancer comprising at least one soluble peptide according to the invention or at least one acid nucleic according to the invention or at least one expression vector according to the invention, or at least one host cell according to the invention and a pharmaceutically acceptable carrier.

Abstract: The present invention relates to the use of interferent RNAs that silence PW1 expression in order to activate adult stem cells in vitro or in vivo, in particular in the context of regenerative medicine.

Abstract: The present invention describes the use of nucleoside analogs for the treatment of viral infections, in particular of an HIV infection, and also compositions comprising at least one of these analogs, and a method for evaluating the sensitivity to said treatment.

Abstract: The invention relates to the use of norbixin and an urucum extract enriched in bixin and/or norbixin as a food. The invention also provides a food preparation comprising norbixin, bixin or an extract comprising at least bixin or norbixin, the preparation being intended to be administered orally, for the protection of mammalian skin against UV-radiation.

Abstract: The invention relates to a haptic controller comprising a base (2), at least one maneuvering body (8) which is movably mounted on the base such that it can be moved under the action of a user, mechanical connection means (4, 15) comprising at least one deformable abutment consisting of an elastomer material between the maneuvering body and the base, and suitable for exerting a monotonous, non-linear resistive effort against an actuating effort of the maneuvering body, at least one sensor (12) placed in the haptic controller in such a way as to generate a signal representative of said actuating effort, and associated built-in or remote means (18) for processing the signal generated by the sensor, in order to supply an output signal for controlling at least one characteristic of a sound.

Abstract: A continuous-time sigma delta radio frequency modulator is provided, including at least two LC resonators coupled in parallel by a coupling capacitive element, producing an at least 4th-order bandpass filter, a frequency response of the bandpass filter presenting at least two poles that can be brought closer together or moved further apart depending on the capacitive element value; a feedback loop for shaping the quantization noise with a predetermined noise transfer function; and an adder for receiving: at one of its inputs an analogue signal; and at its other input a signal provided by the feedback loop; and the output of which is linked to the input of the bandpass filter, the feedback loop including a finite impulse response filter, the coefficients of which being calculated to obtain a noise transfer function which maximizes the signal-to-noise ratio in a signal bandwidth while ensuring the stability of the feedback loop.

Abstract: The invention relates to a method for generating, on the fly and on demand, at least one virtual network (402, 404, 406), adapted for a specific use, on a physical network (200), referred to as an infrastructure network, including physical nodes (204, 206, 208, 210), each of said physical nodes (204, 206, 208, 210) runs at least one network operating system, said method including the following steps: determining, on at least one computer device (202), referred to as a virtual network server, data related to said virtual network (402) to be generated in accordance with said particular use; transmitting, on the basis of said data and to at least a portion of said physical nodes (204, 206, 208, 210), referred to as active nodes, of said infrastructure network (200), a request for creating a virtual node; and creating a virtual node on each of said active nodes by installing a virtual device in each of said active nodes, said virtual network consisting of all of said virtual nodes thus created.

Abstract: A photovoltaic component that includes at least one first array of photovoltaic nano-cells is disclosed. Each photovoltaic component includes an optical nano-antenna exhibiting an electromagnetic resonance in a first resonant spectral band, at least one lateral dimension of the optical nano-antenna being subwavelength in size, and a spectral conversion layer allowing at least part of the solar spectrum to be converted to said first resonant spectral band.

Abstract: The present invention relates to interfering RNAs, in particular miRNAs, capable of specifically blocking the replication of a strain of the HIV virus that is resistant to an antiretroviral compound, and use thereof for treating infections by this type of virus.

Abstract: A probe including NE ultrasonic emitters and NR ultrasonic receivers is applied on the medium to be characterized. Each emitter is activated successively and each time signals are detected on the set of receivers during a time window. Each of the NE×NR signals detected is converted by temporal Fourier transformation to a sum of vibrational components each having its temporal frequency. For each frequency, a matrix NE×NR of complex amplitudes of vibrational components having this frequency is extracted. These matrices are decomposed into singular values, the smallest are eliminated, and the singular vectors associated with the singular values retained, a base of the space of the reception signals is formed, for each frequency. The contribution of each plane wave, characterized by its velocity, in this base is calculated. This contribution is represented in the form of a grey level in a frequency-propagation velocity reference system.

Abstract: The present invention relates to compositions and methods, in particular to methods based on systemic administration of scAAV, for delivering genes to cells of the retina of mammals, and in particular to photoreceptor cells, ganglion cells, glial cells, inner nuclear layer cells or cells of the retinal pigmented epithelium.