Abstract: An estimation apparatus includes an input unit and an approximator. Input information including an image in which a bone appears is input into the input unit. The approximator is configured to determine an estimation result related to bone density of the bone from the input information. The approximator includes a learned parameter to obtain the estimation result.

Abstract: It is an object of the present invention to provide a method for editing or modifying plant genomes (a nuclear genome, a plastid genome, and a mitochondrial genome), and in particular, the editing or modification of a single nucleotide. Specifically, the present invention relates to a method for editing genomic DNAs in plant cells, namely, a nuclear genomic DNA, a plastid genomic DNA and a mitochondrial genomic DNA, wherein the method comprises converting target nucleotides on these genomic DNAs to other nucleotides. This conversion is carried out, for example, with cytidine deaminase, and in particular, with the aforementioned enzyme using a double-stranded DNA as a substrate.

Abstract: According to the present invention, there are provided a method for producing a human T cell, which comprises the steps of inducing an iPS cell from a human T cell, and differentiating the iPS cell into a T cell; a pharmaceutical composition comprising the T cell produced by the method; and a method for cell-based immunotherapy using the method.

Abstract: To provide an information processing apparatus and the like that are capable of dividing an image indicating movement of a subject into a chest region and an abdominal region along anatomical knowledge. The information processing apparatus inputs time-series distance image data acquired by measuring a distance from a subject during a breathing exercise. The apparatus calculates a standard deviation image indicating a standard deviation of values for each pixel in a distance image indicated by the time-series distance image data. The apparatus executes division processing of dividing the standard deviation image into the chest region and the abdominal region of the subject by using a differential value in a direction of an intersection line between a sagittal plane and a frontal plane of the subject with respect to the standard deviation image. The apparatus outputs a result of the division processing by superimposing the result on the standard deviation image.

Abstract: An information processing apparatus and the like capable of calculating a respiratory feature amount necessary for evaluating a breathing motor function of a subject is provided. The information processing apparatus inputs time-series distance image data acquired by measuring a distance from the subject during a breathing exercise and division position data indicating a position at which a chest region and an abdominal region of the subject are divided in the time-series distance image data. The information processing apparatus calculates a standard deviation image indicating a standard deviation of values for each pixel in a distance image indicated by the time-series distance image data. The information processing apparatus calculates a respiratory feature amount indicating a feature of breathing of the subject, based on a divided standard deviation image acquired by dividing the standard deviation image for each divided region being divided at a position indicated by the division position data.

Abstract: A sensor element for detecting electromagnetic waves includes a substrate, an absorber configured to absorb the electromagnetic waves and generate heat, and at least one thermoelectric conversion element disposed between the substrate and the absorber to support a part of the absorber and configured to generate an electromotive force from the heat generated in the absorber by a transverse thermoelectric effect.

Abstract: It is an object of the present invention to provide a method for producing a virus to obtain high-purity virus particles, said method being more efficient than conventional methods.

Abstract: [Problem] To provide a novel compound promising as a probe for a boron neutron capture therapy (BNCT). [Solution] A compound represented by general formula (I) below or a salt thereof.

Abstract: [Problem] To provide a fluorescent probe capable of detecting pancreatic cancer specifically. [Solution] A fluorescent probe for use in the detection of pancreatic cancer, which comprises a compound represented by general formula (I) or a salt thereof.

Abstract: It is an object of the present invention to provide a fusion protein of a molecule that recognizes cancer cells or the like and a mutant streptavidin, wherein the fusion protein is for use in the treatment or diagnosis of a cancer. According to the present invention, provided is a fusion protein, wherein an antigen-binding molecule having a molecular weight of 20,000 or less is bound, via a linker sequence, to the N-terminal side and/or C-terminal side of the amino acid sequence as set forth in SEQ ID NO: 1, provided that the C-terminal amino acid sequence consisting of Pro-Ser-Ala-Ala-Ser His-His-His-His-His-His may be partially or entirely deleted.

Abstract: A magnetic memory element includes an antiferromagnetic layer made of a canted antiferromagnet having a magnetic order with a canted magnetic moment, and a contact layer in contact with the antiferromagnetic layer and made of a different material from the canted antiferromagnet. A roughness of an interface between the antiferromagnetic layer and the contact layer is 1.0 nm or less. A spin current flowing through the contact layer is configured to induce a torque to act on the magnetic order of the antiferromagnetic layer, thereby allowing reversal of the magnetic order.

Abstract: Removable denture data of a removable denture is produced, and disk frame data of a disk frame in which the removable denture is accommodated is produced, thereby building the disk frame based on the disk frame data. Next, a resin disk in which artificial teeth are embedded is produced by arranging the artificial teeth in the disk frame and curing a base resin, and a denture base is milled by milling the resin disk based on the removable denture data, thereby manufacturing the removable denture in which a base side of the artificial teeth is embedded in the denture base. As a result, artificial teeth having an excellent aesthetics may be used, it is possible to firmly join the artificial teeth and the denture base to each other, and it is possible to manufacture a removable denture with a favorable restoration accuracy of the artificial teeth.

Abstract: It is an object of the present invention to provide: a complex of an antigen that is not encapsulated in a nanogel, and a nanogel; and a vaccine preparation comprising the complex.

Abstract: A therapeutic or prophylactic agent for radiation damage associated with radiation exposure, comprising an eosinophil-removing agent as an active ingredient and the like are provided as a technique for efficiently treating or preventing radiation damage associated with radiation exposure. According to the therapeutic or prophylactic agent comprising an eosinophil-removing agent according to the present invention, by suppressing migration and/or infiltration into target tissue and/or proliferation in the tissue of eosinophils and/or inhibiting the activity or function of the eosinophils, pathological conditions such as inflammatory responses and fibrosis of tissue can be suppressed to effectively treat or prevent radiation damage. Moreover, effective radiation therapy can be performed by suppressing radiation damage.

Abstract: Placement of items to be stored is proposed according to how the items to be stored in a chamber performing freezing or refrigerating are cooled. An information processing device including: a prediction section that predicts how items to be stored in a chamber performing freezing or refrigerating are cooled; and an output section that outputs proposal information on the placement of the items to be stored in the chamber performing freezing or refrigerating based on how the items to be stored in the chamber are cooled as predicted by the prediction section.

Abstract: Provided are a standard sample film or a standard sample for use in laser ablation inductively coupled plasma mass spectrometry, the standard sample film or the standard sample containing an organic substance and having a small variation in signal intensity of an ion of a metal element depending on a measurement position; a method for producing a standard sample film; a sample set; a quantitative analysis method; and a transfer film. The standard sample film of the present invention is a standard sample film for use in laser ablation inductively coupled plasma mass spectrometry, the standard sample film containing a polymer, a metal element, and an internal standard, and having a maximum height difference in film thickness of the standard sample film of 0.50 ?m or less.

Abstract: A method of reducing the level of a transcription product in a cell comprising contacting with the cell a composition comprising a double-stranded nucleic acid complex comprising a first nucleic acid strand annealed to a second nucleic acid strand, wherein: (i) the first nucleic acid strand hybridizes to the transcription product and comprises (a) a region consisting of at least 4 consecutive nucleotides that are recognized by RNase H when the strand is hybridized to the transcription product, (b) one or more nucleotide analogs located on 5? terminal side of the region, (c) one or more nucleotide analogs located on 3? terminal side of the region and (d) a total number of nucleotides and nucleotide analogs ranging from 8 to 35 nucleotides and (ii) the second nucleic acid strand comprises (a) nucleotides and optionally nucleotide analogs and (b) at least 4 consecutive RNA nucleotides.

Abstract: The present invention provides the following method as an approach for enriching desired cells, particularly, yolk sac mesoderm cells or amniotic ectoderm cells, contained in an embryogenesis region-specific micropattern structure of a cell cluster formed by differentiation-inducing factors from a colony of pluripotent stem cells such as iPS cells: a method for producing a cell cluster enriched in desired cells from pluripotent stem cells, comprising the step of two-dimensionally culturing the pluripotent stem cells under Wnt signal regulation.

Abstract: By using a model that predicts an environment where elements are arranged in a desired manner, the air environment of the subject space can be easily estimated. An information processing device includes: a storage section storing element models that are created for respective elements which affect an air environment of a space, and that predict the effect of the elements on the air environment of the space; a placement acquisition section acquiring information on the placement of the respective elements provided in a predetermined subject space; and an estimation section estimating the air environment in the subject space using the information on the placement of each of the elements acquired by the placement acquisition section and the element models, which correspond to the elements, stored in the storage section.

Abstract: As one embodiment, the present invention provides a method for growing a ?-Ga2O3-based single crystal film by using HYPE method. The method includes a step of exposing a Ga2O3-based substrate to a gallium chloride-based gas and an oxygen-including gas, and growing a ?-Ga2O3-based single crystal film on a principal surface of the Ga2O3-based substrate at a growth temperature of not lower than 900° C.