Abstract: Described herein are compositions for evaluating nucleic acids, standardized mixture for assessing amounts of at least one target nucleic acid in a sample, and kits comprising the same.

Abstract: Polymeric ionic liquids, methods of making and methods of using the same are disclosed.

Abstract: Photo-initiated polymeric ionic liquids, methods of making and methods of using the same are disclosed. A preferred embodiment for making a photo-initiated polymeric ionic liquid (P-PIL) coated support, comprises: mixing at least one ionic liquid (IL) monomer with at least one photo-initiator; at least partially coating a support with the mixture; and exposing the coated support to UV light to form a photo-initiated polymeric ionic liquid (P-PIL) coated support.

Abstract: Peroxisome proliferator activated receptor (PPAR) compounds, and methods of using the same for treating bone fractures, treating osteoporosis and/or metabolic bone diseases, and inducing osteogenesis and/or chondrogenesis, are disclosed.

Abstract: Ultrastable silver nanoparticles, methods of making the same, and methods of using the same, are disclosed.

Abstract: This invention is a device that provides feedback controlled pressure output that delivers a highly controlled and accurate air stimulus into the larynx for diagnostic use. The device is designed to be significantly more accurate, safer for the patient, and highly modular for easy future modifications compared to previously available commercial devices.

Abstract: A system combines hyperthermia and radiation treatments in a single treatment modality by using a radioactive seed having magnetic, ferromagnetic, or ferrimagnetic properties.

Abstract: A fusion device includes a screw having a head and a shaft. A hollow bone dowel is disposed about the shaft of the screw. The bone dowel is formed from a bone-like, biocompatible, or allograft material.

Abstract: A system combines hyperthermia and radiation treatments in a single treatment modality by using a radioactive seed having magnetic, ferromagnetic, or ferrimagnetic properties.

Abstract: Bi-functional cobalt-containing catalysts useful for making stereospecific compounds and compositions, along with methods of making, and uses thereof in the syntheses of optically pure ?-lactones from aldehydes and ketene are described. Precursors, intermediates, compositions, and particular features of the use if the compositions, such as high enantiomeric selectivity, high yield and low mole percent of catalyst useful are provided.

Abstract: A concise method of producing nylon 11, 12, or 13 precursors from oleic acid or an ester of oleic acid is described. The method involves cross-metathesis reactions as the key C—C bond formation step. Subsequent steps are provided to convert the metathesis product to the corresponding nylon precursors. Also provided are the products of the method.

Abstract: A metering delivery apparatus for injecting bone graft cement includes a body portion, a material containment vessel, an actuator, and a control unit. The body portion includes a drive housing that supports an actuator drivetrain and receiver end that supports the material containment vessel. The actuator has a first end connected to the actuator drivetrain and a second end that supports a moveable portion of the vessel to dispense material in the vessel and a retracting movement that relieves pressure applied to the material. The control unit receives actuator parameter inputs and includes a sensor to detect a signal of at least one of a pressure level and a time period. The sensor provides the detected signal to the control unit such that the control unit operates the actuator between the dispensing and retracting movements based on the detected signal and the actuator parameter inputs.

Abstract: Analogs of PPAR5 and analogs of 20-OH-PGE2, which are PPAR5 agonists and 20-OH-PGE2 antagonists, respectively, and methods of using the same for inducing osteogenesis or chondrogenesis, are disclosed.

Abstract: Described herein are materials and methods useful for the treatment of neurodegenerative disorders and bone disorders, as well as healing wounds, in a subject. Materials described herein include polysaccharide digestive products resulting from the enzymatic hydrolysis of low acyl gellan gum. Also described herein are pharmaceutical compositions comprising one or more of such materials, and methods for their preparation and use.

Abstract: A system combines hyperthermia and radiation treatments in a single treatment modality by using a radioactive seed having magnetic properties.

Abstract: Described herein are compositions for evaluating nucleic acids, standardized mixture for assessing amounts of at least one target nucleic acid in a sample, and kits comprising the same.

Abstract: The antifouling coating is a composite material consisting of fluorinated electroactive bipolymers and magnetic particles. This composite material is coated on a solid surface to make a smooth durable grassy coating. The coating generates electrical current when an electrolytic liquid flows over it, which prevents bacterial cells from attaching to the surface. It prevents virus and protein attachment. It also prevents chemical corrosion of a surface. The composite material itself, and the antifouling method that uses fluoride compounds and electrical current that is generated by the fluid flow are disclosed for a patent. The composite material can be applied to medical devices, biomedical devices, industrial equipment, ship's hulls, food processing equipment, food processors, drinking water distribution systems, and home electrical appliances.

Abstract: Provided herein is a method of producing C11, C12, and C13 nylon precursors from oleic acid or esters of oleic acid, the method involving amide formation, ring-closing metathesis, and hydrogenation. Further provided are the products of the method described. Provided herein is a method for producing a lactam, the method comprising the steps of converting oleic acid or an ester of oleic acid into an amide having a general formula of H3C—(CH2)rCH?CH—(CH2)rCONR—(CH2)n—CH?CH2, wherein n is 1, 2, or 3, and R is either hydrogen or benzyl; subjecting the amide to a ring-closing metathesis reaction to produce an intermediate having a general formula of —(CH2)rCONR—(CH2) n—CH?CH2—, wherein n is 1, 2, or 3, R is either hydrogen or benzyl, and both ends are connected to each other; and hydrogenating the intermediate to produce a saturated lactam. In certain embodiments, the saturated lactam has a formula of —NH—(CH2) 10—CO—.

Abstract: Described herein is an integrated Faraday modulator and Faraday compensator (IFMC) system. Further described are methods of making an IFMC system, methods of customizing an IFMC system for a specific application, and methods of optimizing an IFMC system for a specific application. Further described is a robust 3D Finite Element Model (FEM) for designing and optimizing an IFMC system. Further described are optical instruments comprising an integrated Faraday modulator and Faraday compensator requiring only one optical crystal.

Abstract: A method for regulating Src and its downstream signaling pathway which includes binding between Src and Na+/K+-ATPase is disclosed. The Na+/K+-ATPase/Src complex is a functional receptor for cardiotonic steroids such as ouabain. Also disclosed are Src inhibitors or activators which include either Na+/K+-ATPase or Src that interfere with the interaction between the Na/K-ATPase and Src, act via a different mechanism from ATP analogues, and is pathway (Na+/K+-ATPase) specific. Also disclosed is use of said Src-modulating peptides for treatment of cancer.