Abstract: A gait motion assisting apparatus of the present invention includes an actuator unit controlling driver so that assisting force calculated by applying gait motion timing based on detected thigh phase angle to output pattern saved data is imparted to lower leg, and a terminal device capable of wireless-communicating with control device of the actuator unit. The terminal device can receive assisting force setting value including assisting force imparting period during gait cycle and create, based on the assisting force setting value, output pattern setting data indicating a relationship between the gait motion timing and a size of assisting force to be imparted to the lower leg. The control device is configured to overwrite-save the output pattern setting data received from the terminal device as the output pattern saved data.
Type:
Grant
Filed:
November 5, 2018
Date of Patent:
December 20, 2022
Assignees:
Suncall Corporation, Kyoto University, National University Corporation Kyoto institute of Technology
Inventors:
Rei Takahashi, Yukinobu Makihara, Tadao Tsuboyama, Koji Ohata, Yuichi Sawada, Yoshiyuki Higashi
Abstract: Methods and compositions are provided for the therapeutic use of hedgehog agents, for enhancing bone growth and regeneration in diabetic or pre-diabetic patients, including repair following injury, osseointegration of implants, and the like. In some embodiments of the invention, the compositions are administered locally, e.g. by injection or implantation at the site of an injury.
Type:
Grant
Filed:
January 8, 2018
Date of Patent:
December 20, 2022
Assignee:
The Board of Trustees of the Leland Stanford Junior University
Inventors:
Michael T. Longaker, Irving L. Weissman, Ruth Tevlin, Charles K. F. Chan
Abstract: The present invention discloses a method for effectively decomposing mixed wolframite and scheelite ore in an alkaline system, specifically comprising steps of: grinding mixed wolframite and scheelite ore, putting in an autoclave, adding an appropriate amount of water, and then adding sodium phosphate, sodium hydroxide and calcium fluoride for decomposition, and treating by solid-liquid separation to obtain crude sodium tungstate solution. The present invention has the advantage that the high-efficiency decomposition of the mixed wolframite and scheelite ore can be realized with low consumption of leaching agents. By this method, the mixed wolframite and scheelite ore can be directly treated by an existing tungsten smelting autoclave, with low leaching cost, high decomposition rate and easy industrial application.
Type:
Grant
Filed:
December 15, 2019
Date of Patent:
December 20, 2022
Assignee:
Jiangxi University of Science and Technology
Abstract: The invention provides a compound of formula (I): wherein R is as described herein. The invention also provides a process for the preparation of the compound.
Abstract: A feeding bottle includes a bottle enclosure defining a hollow bottle chamber, wherein the enclosure defines a feeding outlet at a first end and an attachment structure 26 at a second end. A bottom housing defines an instrument compartment extending between a closed exterior portion of the bottom housing and a separation surface within the bottom housing, wherein the bottom housing is configured for detachable connection to the attachment structure 26 of the bottle enclosure. A relief valve is positioned within the separation surface of the bottom housing. A pressure sensor is positioned adjacent the separation surface of the bottom housing and connected by a passageway to the instrument compartment in the bottom housing, wherein the pressure sensor is configured to detect changes of pressure in the bottle enclosure.
Type:
Grant
Filed:
October 25, 2019
Date of Patent:
December 20, 2022
Assignees:
The Board of Trustees of the University of Alabama, The UAB Research Foundation
Inventors:
Eduard S. Sazonov, Ariel A. Salas, Paula Catherine Chandler-Laney
Abstract: An apparatus and a method for preparing a multi-directional continuous fiber-reinforced composite material. The apparatus includes an electrostatic fiber-splitting device configured to controllably split a fiber bundle, a powder spreading device configured to spread a powder, and a pre-press molding device configured to cut the fiber and compact the powder. The electrostatic fiber-splitting device includes a rotatable fiber-splitting table. The pressing plate is controlled by an electromagnet, and the pressing plate is energized to generate a high-voltage electrostatic field to disperse the continuous fiber bundle into monofilament fibers.
Type:
Grant
Filed:
September 16, 2021
Date of Patent:
December 20, 2022
Assignee:
Shaanxi University of Science & Technology
Abstract: The present invention describes methods for quantifying and analyzing cell migration and drug screening. Such methods include a gel (or a hydrogel) comprising a polymer, and cells that forms an oxygen gradient within the gel by controlling the balance of the diffusion of oxygen through the top of the gel and by the consumption of oxygen uptake by the cells. The migration of the cells is determined while the cells are grown in the gel of the present invention.
Type:
Grant
Filed:
July 19, 2017
Date of Patent:
December 20, 2022
Assignees:
The Johns Hopkins University, The Trustees of the University of Pennsylvania
Inventors:
Sharon Gerecht, Daniel Lewis, Kyung Min Park, T. S. Karin Eisinger, M. Celeste Simon
Abstract: An instrument for separating ions may include an ion source in a first pressure environment at a first pressure and configured to generate ions from a sample, an ion separation instrument, controlled to an instrument pressure that is less than the first pressure, and configured to separate ions as a function of at least one molecular characteristic and an interface, controlled to a second pressure less than the first pressure and greater than the instrument pressure, for transporting the generated ions from the first pressure environment into the ion separation instrument operating at the instrument pressure. The interface may include a sealed ion funnel defining an axial passageway therethrough, and an ion carpet sealed to the first ion funnel. A portion of the axial passageway tapers from a first cross-sectional area to a reduced cross-sectional area such that the tapered axial passageway defining a virtual jet disrupter therein.
Type:
Grant
Filed:
September 8, 2021
Date of Patent:
December 20, 2022
Assignee:
The Trustees Of Indiana University
Inventors:
Martin F. Jarrold, Staci N. Anthony, Benjamin E. Draper
Abstract: The invention relates to synthetic liver-specific promoters and expression constructs for producing polypeptides and functional nucleic acids in the liver of a subject. The invention further relates to optimized polynucleotide sequences encoding Factor IX proteins, vector comprising the same, and methods of using these compositions to treat a bleeding disorder.
Type:
Grant
Filed:
May 31, 2018
Date of Patent:
December 20, 2022
Assignee:
The University of North Carolina at Chapel Hill
Abstract: A method for enhancing an expression of insulin like growth factor 1 receptor in a mesenchymal stem cell is provided. The method includes culturing the mesenchymal stem cell expressing insulin-like growth factor 1 receptor in a medium containing platelet-derived growth factor BB (PDGF-BB) to enhance the expression of insulin like growth factor 1 receptor in the mesenchymal stem cell.
Abstract: Disclosed are an organic thin film including a semiconducting polymer including a ligand that is metal-coordination bondable or is metal-coordination bonded and an elastomer including a ligand that is metal-coordination bondable or is metal-coordination bonded, wherein the semiconducting polymer and the elastomer are configured to be dynamic intermolecular bonded by a metal-coordination bond, an organic sensor, and an electronic device.
Type:
Grant
Filed:
May 22, 2019
Date of Patent:
December 20, 2022
Assignees:
Samsung Electronics Co., Ltd., The Board of Trustees of the Leland Stanford Junior University
Inventors:
Youngjun Yun, Donghee Son, Jin Young Oh, Zhenan Bao, Toru Katsumata
Abstract: A multifunctional camera system having a bendable arm configured to be inserted into the thoracic cavity of a patient and camera head at a distal end of the bendable arm. The camera head has a high definition video camera and a light source. The camera head has a view adjustment mechanism for changing a view angle of the camera without changing the position of the camera head. A controller controls the view adjustment mechanism under command of a surgeon.
Type:
Grant
Filed:
April 5, 2019
Date of Patent:
December 20, 2022
Assignee:
Board of Trustees of Southern Illinois University
Inventors:
Traves Crabtree, Timothy York, Mitch McKay, Mingshao Zhang
Abstract: A game system includes: a typing game apparatus; and a server, wherein: the server includes: a server communication unit for communicating with the typing game apparatus; a clock unit for clocking the time and date; a storage unit for storing game data with a definite usable term for use in the typing game; a time limit judgment unit for judging expired data that an usable term of game data passes; and a command unit for issuing a deletion command for deleting the expired data based on the judgment result to the typing game apparatus; and the typing game apparatus includes: a game communication unit for communicating with the server; a game control unit for controlling a typing game; a data storage unit for storing the game data; and a data management unit for deleting the expired data based on the deletion command.
Abstract: A method for forming crystalline solid dispersions (CSDs) of a pharmaceutical agent with low water solubility is described. The properties of the CSDs are described. Also described is the enhancement of bioavailability of the pharmaceutical agent resulting from formation of the CSD.
Type:
Grant
Filed:
April 14, 2020
Date of Patent:
December 20, 2022
Assignee:
The Curators of the University of Missouri
Abstract: Provided is a method of producing semiconductor nanoparticles that exhibit a band-edge emission, and are superior in quantum yield. The method includes raising the temperature of a first mixture containing a silver (Ag) salt, a salt containing at least one of indium (In) and gallium (Ga), a solid compound that serves as a supply source of sulfur (S), and an organic solvent to a temperature in a range of from 125° C. to 175° C., and heat-treating, subsequent to the raising of the temperature, the first mixture at a temperature in a range of from 125° C. to 175° C. for three seconds or more to obtain a solution containing semiconductor nanoparticles, and decreasing the temperature of the solution containing semiconductor nanoparticles. The solid compound that serves as a supply source of S contains thiourea.
Type:
Grant
Filed:
February 15, 2019
Date of Patent:
December 20, 2022
Assignees:
OSAKA UNIVERSITY, National University Corporation Tokai National Higher
Education and Research System, NICHIA CORPORATION
Abstract: A method of monitoring respiration with an acoustic measurement device, the acoustic measurement device having a sound transducer, the sound transducer configured to measure sound associated with airflow through a mammalian trachea, the method includes correlating the measured sound into a measurement of tidal volume and generating at least one from the group consisting of an alert and an alarm if the measured tidal volume falls outside of a predetermined range.
Type:
Grant
Filed:
October 11, 2021
Date of Patent:
December 20, 2022
Assignees:
Thomas Jefferson University, RTM Vital Signs LLC
Inventors:
Jeffrey I Joseph, Noud Van Helmond, Marc C Torjman, Denise L Devine, Nance K Dicciani, Channy Loeum
Abstract: The present invention provides a method for controlling colocalization of two or more proteins in a cell. The method comprises expressing the proteins, scaffold RNA molecules having binding motifs for the proteins, and a trigger RNA molecule in the cell. In the presence of the trigger RNA molecule, a scaffold may be assembled (ON) by the scaffold RNA molecules via hybridization such that the proteins may be colocalized; or disassembled (OFF) such that the proteins may be separated and not colocalized. The proteins may provide a biological activity when colocalized or not colocalized.
Abstract: The present invention provides a method for robot action imitation learning in a three-dimensional space and a system thereof, relates to the technical fields of artificial intelligence and robots. A method based on a series-parallel multi-layer backpropagation (BP) neural network is designed for robot action imitation learning in a three-dimensional space, which applies an imitation learning mechanism to a robot learning system, under the framework of the imitation learning mechanism, to train and learn by transmitting demonstrative information generated from a mechanical arm to the series-parallel multi-layer BP neural network representing a motion strategy.
Abstract: A resistance control system of an amusement attraction includes a support assembly having a base, a pivot joint, and a support beam extending between the base and the pivot joint. The resistance control system includes a spring plate coupled to the pivot joint of the support assembly, and includes at least one spring engaged with the spring plate. Additionally, the resistance control system includes an actuator plate positioned between the spring plate and the base of the support assembly, as well as at least one actuator coupled between the actuator plate and the base. The at least one actuator is configured to move and secure the actuator plate relative to the pivot joint to adjust a resistance to movement about the pivot joint.
Type:
Grant
Filed:
May 18, 2021
Date of Patent:
December 20, 2022
Assignee:
Universal City Studios LLC
Inventors:
Steven C. Blum, Mark Allan Stepanian, Jordan Dillon Barner, Tyler James Blankenship
Abstract: A method for operating a power transmitting device in a wireless communication system is provided. The method includes receiving feedback information corresponding to power harvest from a plurality of electronic devices, performing beam scheduling based on the feedback information, and transmitting power to the plurality of the electronic devices using at least one beam based on the beam scheduling.
Type:
Grant
Filed:
December 26, 2019
Date of Patent:
December 20, 2022
Assignee:
Industry-Academic Cooperation Foundation, Yonsei University