Abstract: The disclosed embodiments relate to the design of a preconcentrator system for preconcentrating air samples. This preconcentrator system includes a plurality of preconcentrators that preconcentrate the air samples prior to chemical analysis, and a delivery structure comprising a manifold that selectively routes a sample airflow to the plurality of concentrators so that the plurality of preconcentrators receive a sample airflow concurrently or individually.

Abstract: Disclosed is a stereo matching method of images performed by a system implemented by a computer, including the steps of: receiving a pair of images obtained at different time points; generating a feature map by extracting features of each pixel of the pair of images; generating sequentially cost volumes for partial time points based on the feature map and generating a feature map for the entire disparity by fusing the cost volumes using 2D convolution; and generating a final disparity map by refining the generated feature map.

Abstract: A method for detecting at least one surgery-related condition within a surgical site of a subject following a surgery is disclosed. The method includes providing at least one modular nucleic acid assay, obtaining a surgical drainage sample from the surgical site of the subject, isolating a nucleic acid-containing portion from the sample, and detecting and quantifying at least a portion of the amount of nucleic acids within the nucleic acid-containing portion using the at least one nucleic acid assay to produce at least one assay result. At least one assay result may be provided to a practitioner and used to select at least one additional treatment. The modular nucleic acid assays may be used in any combination with a single surgical drainage sample to assess minimal residual cancer, local immune environment, infection, transplant organ rejection, and/or free flap failure.

Abstract: A system and method for measuring biomechanical properties of tissues without external excitation are capable of measuring and quantifying these parameters of tissues in situ and in vivo. The system and method preferably utilize a phase-sensitive optical coherence tomography (OCT) system for measuring the displacement caused by the intrinsic heartbeat. The method allows noninvasive and nondestructive quantification of tissue mechanical properties. Preferably, the method is used to detect tissue stiffness and to evaluate its stiffness due to intrinsic pulsatile motion from the heartbeat. This noninvasive method can evaluate the biomechanical properties of the tissues in vivo for detecting the onset and progression of degenerative or other diseases and evaluating the efficacy of therapies.

Abstract: Provided herein are agents, such as antibodies, antibody-drug conjugates, or chimeric antigen receptors, that target EphA10. Methods of treating cancer are provided, comprising administering to a patient in need thereof an effective amount of an EphA10-targeting agent. The patient may be selected for treatment if the cancer expresses an increased level of EphA10.

Abstract: Systems and methods for detecting ?9-tetrahydrocannabinol (?9-THC) are described. In many embodiments, the detection of ?9-THC can be achieved by oxidizing ?9-THC to corresponding oxidized products. The oxidation of ?9-THC can be achieved chemically or electrochemically. The oxidized products of ?9-THC can exhibit different photophysical and electrochemical properties compared to ?9-THC. Many embodiments implement integrating ?9-THC detection into a multimodal marijuana breathalyzer device.

Abstract: The present disclosure provides a leakage measurement error compensation method based on cloud-edge collaborative computing, implemented on a communication network formed by interconnection between a leakage current edge monitoring terminal and a power consumption management cloud platform, and including the following steps: monitoring, by the leakage current edge monitoring terminal, leakage current data, and sending the leakage current data to the power consumption management cloud platform; iteratively training, by the power consumption management cloud platform, a pseudo-leakage compensation model by using the received leakage current data, continuously updating pseudo-leakage model parameters, and feeding the pseudo-leakage model parameters back to the leakage current edge monitoring terminal; and processing, by the leakage current edge monitoring terminal, the leakage current data according to the pseudo-leakage compensation model parameters, so as to eliminate the influence of a pseudo-leakage phenomen

Abstract: The present invention relates to a method for screening an anticancer agent by causing drosophila having the characteristics of a) expression of mutant Ras85D, b) deletion or suppressed expression of a p53 gene, c) overexpression of a cyclin E gene, and d) deletion or suppressed expression of a Med gene to ingest a test substance and comparing the survival rate thereof with the survival rate of drosophila that did not ingest the test substance. The present invention also relates to a combination drug of at least two kinase inhibitors for treatment of pancreatic cancer and to kinase inhibitors for use in said combination drug.

Abstract: The present disclosure provides methods of imaging cancerous cells in a subject, wherein the cancerous cells are localized to the skeletal system or central nervous system of the subject, the method comprising administering to the subject an effective amount of 18F-fluoroacetate, detecting a first signal emitted by 18F-fluoroacetate, and generating an image representative of the location and/or amount of the first signal to image the cancerous cells. In some embodiments, the methods further comprising diagnosing, prognosing, staging, and/or monitoring the progression of a disease or disorder, such as acute lymphoblastic leukemia and/or leptomeningeal disease.

Abstract: A preparation method of a high-strength and high-toughness A356.2 metal matrix composites for a hub is provided, including the following preparation process steps: preparation of a (graphene+HfB2)-aluminum master alloy wire; A356.2 alloy melting, master alloy addition, refining, and pressure casting; solution and aging treatment; shot blasting, finishing, alkaline/acid cleaning, anodic oxidation, and finished product packaging. In this way, two systems of two-dimensional nano-structure graphene nucleation and in-situ self-nucleation are introduced to complement each other, a second phase of silicon in A356.2 is refined by multi-dimensional scaling, and multi-dimensional nano-phases strengthen the aluminum-based composite material simultaneously. The preparation method solves the problems of limiting the strength, hardness, plasticity and toughness during the application of common A356.

Abstract: Two-dimensional (2D) high-entropy transition metal dichalcogenide (TMDC) alloy compositions, methods of synthesizing the TMDC alloys, physical/chemical properties of the TMDC alloys, and uses of the TMDC alloys as catalysts in electrochemical reactions are disclosed.

Abstract: The present invention provides methods and compositions for treating or preventing melanoma with S-equol. The S-equol may be administered alone or in combination with one or more cytotoxic or immunotherapeutic compound or molecule.

Abstract: Disclosed is a driving circuit of a stretchable display capable of being stretched, which includes a driving part that includes a driving transistor connected with a light-emitting element and drives the light-emitting element depending on a signal of a data line, a switching transistor that is connected between the driving part and the data line and includes a gate terminal connected with a first gate line, and a stretch-sensitive sensor that is connected with the switching transistor between the driving part and the data line, and the stretch-sensitive sensor may include a stretch-sensitive material whose resistance characteristic changes depending on a stretching force applied to the stretchable display.

Abstract: Herbal compositions comprising dihydromyricetin (DHM) and methods of use. The herbal compositions include DHM in combination with other ingredients to form compositions that can significantly improve the quality and duration of sleep, reduce the time for onset of improved sleep quality and duration, and treat or alleviate the symptoms of sleep-related disorders and neurological conditions. The composition is a therapeutic alternative to drugs to alleviate sleep disorders and related symptoms and ailments.

Abstract: An apparatus includes a battery pack with N battery bricks, each with a DC output voltage. The output of each brick is connected in series providing a bus voltage. Each brick includes battery power modules (“BPMs”) connected in parallel and each connected to a battery cell. Each BPM charges/discharges the connected battery cell. Each brick has a battery brick controller that provides a control signal to each brick's BPMs. A control signal of a BPM is derived from a BPM error signal that includes a battery cell current of the battery cell of BPM subtracted from a summation of an average current signal, a local droop current and a balancing current. The balancing current is based on a current SOC of the battery cell connected to the BPM and a desired SOC for the battery cell connected to the BPM. A BMS derives the balancing current for the BPMs.

Abstract: Devices and methods described herein decode a sequence of coded symbols by guessing noise. In various embodiments, noise sequences are ordered, either during system initialization or on a periodic basis. Then, determining a codeword includes iteratively guessing a new noise sequence, removing its effect from received data symbols (e.g. by subtracting or using some other method of operational inversion), and checking whether the resulting data are a codeword using a codebook membership function. This process is deterministic, has bounded complexity, asymptotically achieves channel capacity as in convolutional codes, but has the decoding speed of a block code. In some embodiments, the decoder tests a bounded number of noise sequences, abandoning the search and declaring an erasure after these sequences are exhausted. Abandonment decoding nevertheless approximates maximum likelihood decoding within a tolerable bound and achieves channel capacity when the abandonment threshold is chosen appropriately.

Abstract: A transdermal patch is provided, wherein the patch comprises a cross-linked poly(ethylene oxide) hydrogel loaded with naltrexone, or a pharmaceutically acceptable salt or solvate thereof, and an occlusive adhesive tape. The poly(ethylene oxide) hydrogel has a crosslink density of at least 4.5×10?4 mol cm?3 and not more than 16×10?4 mol cm?3. Also provided are methods for preparing naltrexone-loaded cross-linked poly(ethylene oxide) hydrogels, transdermal patches for use as a medicament, for example in the treatment of a specified condition with LDN therapy.

Abstract: Compositions and methods of treatment for multiple myeloma (MM) are disclosed that include a liposome with a lipid bilayer shell enclosing a fluid-filled center, a targeting moiety coupled to the outer surface of the shell, a treatment compound disposed within the lipid bilayer shell or within the fluid-filled center, and an efficacy-enhancing compound disposed within the lipid bilayer shell or within the fluid-filled center. In some embodiments, the targeting moiety is PSGL-1, the proteasome-inhibiting compound is bortezomib, and the BMME-disrupting agent is a CXCR4 inhibitor or ROCK inhibitor.

Abstract: The invention relates to a robot controller controlling a robot arm, the robot controller is configured to maintain the robot arm in a static posture when only gravity is acting on the robot arm and allow change in posture of the robot arm when an external force different from gravity is applied to the robot arm. The free-drive mode of operation is activatable by a user establishing a free-drive activation signal to the robot controller, which then is configured to: —monitor a value of at least one joint sensor parameter; —compare the value of the joint sensor parameter to a maintain free-drive joint sensor parameter threshold value; —maintain the robot arm in said free-drive mode of operation for a predetermined maintain free-drive period of time, and —leave the free-drive mode of operation if the value of the joint sensor parameter docs not exceed the maintain free-drive joint sensor parameter threshold value within the maintain free-drive period of time.

Abstract: Systems and methods for displaying super saturated color. Image data for display on a display or viewing device with a potential white luminance in a standard system with a maximum luminance is processed such that colors near the white point are reduced to a limited luminance. As the chroma of the displayed color is increased, a luminance attenuation is decreased. The scaling of the reduction is operable to be a linear function, a non-linear function, or any other function.