Abstract: An embodiment in accordance with the present invention includes an EGS configured to allow the commercial production of electrical energy. One criteria of an EGS according to the present invention is that the temperature and volume of the fluids extracted are sufficiently high and large enough as to allow the commercial production of electrical energy. The system is able to operate for at least N years before the extracted fluid falls below the minimum temperature needed for energy production. Additionally, fractures are separated from each other by a sufficiently large volume of rock (Vcrit) relative to the fractures surface area such that the ratio of the rate of heat extraction to the rate of heat supply controlled by the thermal conductivity of the rock is such that the intervening rock is cooled at a rate that is sufficiently slow to be economic.
Type:
Application
Filed:
July 21, 2021
Publication date:
November 11, 2021
Applicant:
The Johns Hopkins University
Inventors:
Bruce D. MARSH, Markus HILPERT, Peter Anderson GEISER
Abstract: The present disclosure provides methods to quantify VCP phosphorylation at specific amino acid residue to predict responsiveness of a subject having a cancer or tumor to a genotoxic treatment, guide treatment decisions, select subjects for clinical trials, and evaluate the clinical efficacy of certain therapeutic interventions.
Abstract: The invention provides a radiopharmaceutical compound or composition comprising a radiolabeled linear peptide that binds specifically to Glypican-3 (GPC3) expressed on a surface of a cell. Preferably, the linear peptide is conjugated to one or more 18F atoms.
Abstract: Disclosed is a speech processing apparatus and method using a densely connected hybrid neural network. The speech processing method includes inputting a time domain sample of N*1 dimension for an input speech into a densely connected hybrid network; passing the time domain sample through a plurality of dense blocks in a densely connected hybrid network; reshaping the time domain samples into M subframes by passing the time domain samples through the plurality of dense blocks, inputting the M subframes into gated recurrent unit (GRU) components of N/M-dimension; outputting clean speech from which noise is removed from the input speech by passing the M subframes through GRU components.
Type:
Application
Filed:
May 5, 2021
Publication date:
November 11, 2021
Applicants:
Electronics and Telecommunications Research Institute, The Trustees of Indiana University
Inventors:
Minje KIM, Mi Suk LEE, Seung Kwon BEACK, Jongmo SUNG, Tae Jin LEE, Jin Soo CHOI, Kai ZHEN
Abstract: A dual host system for OLEDs that contains hole-transporting indolocarbazole and electron-transporting indolocarbazole exhibiting superior performance in the OLEDs is disclosed.
Type:
Application
Filed:
July 2, 2021
Publication date:
November 11, 2021
Applicant:
Universal Display Corporation
Inventors:
Lichang ZENG, Vadim ADAMOVICH, Chuanjun XIA, Michael WEAVER
Abstract: A system in Elliptic Curve Cryptography (ECC) that offers secure encoding and mapping of a message to the curve E against encryption attacks, such as Chosen Plaintext Attack (CPA) and Ciphertext Only Attack (COA). The system includes, a method to convert the text message to numerical values with manipulation using Initial Vector IV. In addition, the system provides, a method to revert the manipulated values to their original value.
Abstract: A process for producing polyarylene ether nitrile, in which an N-methylpyrrolidone solvent can be efficiently recovered. The process includes the following steps: mixing N-methylpyrrolidone, potassium carbonate, 2,6-dichlorobenzonitrile, dihydric phenol and toluene, and carrying out a dehydration reaction and a polymerization reaction in sequence to obtain a high-viscosity polyarylene ether nitrile solution; then pelletizing and conveying polyarylene ether nitrile particles together with methanol to a primary vibrating screen to complete a primary replacement of N-methylpyrrolidone; then using a secondary vibrating screen to complete a secondary replacement of the solvent; subsequently, grinding the polyarylene ether nitrile particles and carrying out an extraction with methanol, and then centrifuging, washing with water and drying to obtain purified polyarylene ether nitrile powder; and finally distilling replacement liquid and centrifugation liquid to separate methanol from N-methylpyrrolidone.
Type:
Application
Filed:
August 13, 2020
Publication date:
November 11, 2021
Applicant:
University of Electronic Science and Technology of China
Inventors:
Xiaobo LIU, Mingzhen XU, Kun JIA, Lifen TONG
Abstract: Disclosed herein are cyclodextrin molecules covalently modified to store and release nitric oxide, as well as methods of making and uses thereof. The covalently modified cyclodextrin molecules may be tailored, in several embodiments, to release nitric oxide in a controlled manner and are useful for reduction and/or eradication of bacteria and for the treatment of disease.
Type:
Application
Filed:
May 17, 2021
Publication date:
November 11, 2021
Applicant:
The University of North Carolina at Chapel Hill
Abstract: An SOP for connection to a first feeder in an electricity distribution network, the SOP being configured to, when a feeder connected to the SOP is faulty, apply a diagnostic voltage to the feeder and make current and voltage measurements at the connection of the SOP to the feeder while the diagnostic voltage is being applied.
Type:
Application
Filed:
October 9, 2019
Publication date:
November 11, 2021
Applicant:
University College Cardiff Consultants Ltd
Abstract: Methods are provided for reducing type 2 cytokine-mediated inflammation, for example by reducing IL-5 and Il-13 activity, using native and variant neuromedin B (Nmb) peptides or coding sequences. Such methods can be used to treat an inflammatory disorder, such as asthma, COPD or an allergic reaction. Also provided are modified Nmb peptides.
Type:
Application
Filed:
October 3, 2019
Publication date:
November 11, 2021
Applicant:
Rutgers, The State University of New Jersey
Abstract: Disclosed are methods and compositions related to methods of treating, ameliorating, mitigating, slowing, arresting, preventing or reversing various diseases and conditions, including age-related obesity, age-related increases in blood lipid levels, age-related decreases in insulin sensitivity, age-related decreases in memory function, and age-related changes in eye function such as macular degeneration. The methods comprise administering nicotinamide mononucleotide (NMN) to a subject. In some embodiments, the administration can be oral administration. Also disclosed are pharmaceutical compositions comprising NMN.
Abstract: Various embodiments of a system and method for pruning binary neural networks by analyzing weight flipping frequency and pruning the binary neural network based on the weight flipping frequency associated with each channel of the binary neural network are disclosed herein.
Type:
Application
Filed:
May 11, 2021
Publication date:
November 11, 2021
Applicant:
Arizona Board of Regents on Behalf of Arizona State University
Abstract: A mouthwash for fluorescence endoscopic dental imaging includes at least one fluorescent dye and a liquid base. A method for fluorescent endoscopic dental imaging includes orally administering a mouthwash to a subject; waiting a predetermined period of time; removing excess mouthwash from the subject; illuminating the subject with visible or near-infrared light; and capturing fluorescent light from the subject to create an image.
Type:
Application
Filed:
April 26, 2021
Publication date:
November 11, 2021
Applicant:
Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
Abstract: A method of making cyclobutane-1,2-diacid building blocks includes using trans-cinnamic acid in its beta form (head to head packing) and photodimerizing the trans-cinnamic acid to create cis-cyclobutane-1,2-dicarboxylic acid (CBDA4).
Abstract: Immunogenic potential of a virus-like particle (VLP) for use in developing a vaccine is predicted by comparing order parameters of the VLP and a target virus. The method may include determining a numerical value of an order parameter and relative composition of viral coat proteins of a target virion (virus). A numerical value of an order parameter and relative composition of the surface proteins of a VLP is also determined. The numerical value of the order parameter and relative composition of the viral coat proteins of the target virion (virus) are compared to the numerical value of the order parameter and relative composition of the VLP to determine if the VLP satisfies pre-defined matching criteria indicative of high immunogenic potential and corresponding vaccine efficacy.
Type:
Application
Filed:
May 6, 2021
Publication date:
November 11, 2021
Applicant:
The Board of Trustees of Western Michigan University
Inventors:
Robert Allen Makin, III, Steven Michael Durbin
Abstract: A device may obtain field images of a tissue sample, apply, to the field images, spatial distortion and illumination-based corrections (including corrections for photobleaching of reagents) to derive processed field images, identify, in each processed field image, a primary area including data useful for cell or subcellular component characterization, identify, in the processed field images, areas that overlap with one another, and derive information regarding a spatial mapping of cell(s) and/or sub-cellular components of the tissue sample. Deriving the information may include performing segmentation based on the data included in the primary area of each processed field image, and obtaining flux measurements based on other data included in the overlapping areas.
Abstract: The present disclosure provides methods of making nicotinoyl riboside compounds or derivatives of formula (I): wherein X?, Z1, Z2, n, R1, R2, R3, R4, R5, R6, R7, and R8 are described herein, reduced analogs thereof, modified derivatives thereof, phosphorylated analogs thereof, and adenylyl dinucleotide conjugates thereof, or salts, solvates, or prodrugs thereof; and novel crystalline forms thereof.
Type:
Application
Filed:
June 22, 2020
Publication date:
November 11, 2021
Applicants:
The Queen's University of Belfast, ChromaDex Inc.
Inventors:
Marie Eugenie Migaud, Philip Redpath, Kerri Crossey, Richard Cunningham, Aron Erickson, Richard Nygaard, Amanda Storjohann
Abstract: The present application discloses a method for planting and processing high-yield forage in high altitude area, and belongs to the technical field of feed preparation in a high altitude area. The planting method of the present application comprises the steps of: intercropping maize and soybeans at an altitude of more than 3000 m, and the maize varieties include Demeiya No. 1 and Demeiya No. 3, the soybean varieties include Zhongdou No. 39 and Huachun No. 6. The planting method of the present application can realize the successful planting of maize and soybeans in a high altitude area (>3000 m), and can greatly improve the biological yield.
Type:
Application
Filed:
September 30, 2020
Publication date:
November 11, 2021
Applicant:
Sichuan Agricultural University
Inventors:
Yanhong YAN, Wenyu YANG, Weiguo Liu, Qiyin XIAO, Dongming Chen, Xingjin Wen, Mei Xu, Jizhi Yang, Zhaochang Du, Guoqian Zhu
Abstract: An encryption method and apparatus based on homomorphic encryption using an odd function property. The encryption method includes generating a ciphertext by encrypting data, and bootstrapping the ciphertext by performing a modular reduction based on an odd function property for a modulus corresponding to the ciphertext.