Abstract: The present invention contemplates a method and/or system for accurately and accelerated synchronization of communication networks. The method contemplates providing a virtual clock module in which all nodes of a network use the module in an identical manner and wherein the virtual clock module of nodes is generally a data stream whose element is the virtual time with whatever notice made is in communication with at that instant. In a preferred embodiment of the invention, the method or system is processed using a finite impulse filter. The virtual clock in each node is responsible for generating a stream of data in which one may consider as virtual time. Each sample of the discrete time stream is constructed by its nearest neighbor of the node concerned communicating the current sample of its own virtual time stream to the node.

Abstract: A polypeptide, a pharmaceutical composition including a polypeptide, and a method for treating a condition using a polypeptide are provided. The polypeptide includes an amino acid sequence according to the general formula X1-X2-X3, wherein X1 and X3 are independently absent or comprise a transduction domain, X2 includes Z3, and Z3 is selected from the group consisting of serine or phosphoserine analogs. The pharmaceutical composition includes a polypeptide including an amino acid sequence according to the general formula X1-X2-X3 and one or more components selected from the group consisting of a pharmaceutically acceptable carrier, a calcium channel blocker, and a combination thereof. X1 and X3 are independently absent or comprise a transduction domain, X2 includes Z3, and Z3 is selected from the group consisting of serine or phosphoserine analogs.

Abstract: Methods and apparatuses to non-destructively and periodically sample a small quantity of intracellular proteins and mRNA from the same single cell or cells for an extended period of time. Specifically, describe herein are non-perturbative methods for time-resolved, longitudinal extraction and quantitative measurement of intracellular proteins and nucleic acids from a variety of cell types using systems including nanostraws.

Abstract: The present invention provides a nanoparticle capable of binding specifically to a target protein in a solution and precipitating with the target protein out of the solution upon addition of the target protein to the solution. The precipitation may be reversed release the target protein from the nanoparticle, which may be reused for precipitating the target protein. Also provided are a method for purifying a target protein by affinity precipitation using the nanoparticle without chromatography and a method for preparing the nanoparticle.

Abstract: Provided herein are small molecules that bind to ASH1L and inhibit ASH1L activity, and methods of use thereof for the treatment of disease, including acute leukemia, solid cancers and other diseases dependent on activity of ASH1L.

Abstract: An inspection system and method with a variable-diameter traveling robot for inspection of a natural gas pipeline. The inspection system includes a pipeline inspection robot, a cable reel, a hydraulic pump and an information acquisition control terminal. The pipeline inspection robot includes an electronic cabin and a traveling mechanism. The electronic cabin includes a first digital camera, a second digital camera, a first digital camera mounting plate, a second digital camera mounting plate, a drum, a printed circuit board, a magnetic flux leakage probe, and a backup battery. The traveling mechanism includes a first traveling part, a second traveling part, an inner ratchet, an inner ratchet base, a slider, a long shaft, a hydraulic cylinder, and a hydraulic pipe. The cable reel includes a power line, a conversion module, and a communication line. The information acquisition control terminal is a mobile terminal having an analysis module and a control module.

Abstract: Systems, methods and devices for promoting recovery from a stroke induced loss of motor function in a subject. In certain aspects, the system includes at least one electrode, and an operations system in electrical communication with at least one electrode, wherein the at least one electrode is constructed and arranged to apply current across the brain of the subject and to record low frequency oscillations from a perilesional region of the subject. In certain aspects, provided is a method comprising placing at least one recording electrode in electrical communication in a perilesional region of the subject; placing at least one stimulation electrode in electrical communication with the brain of the subject; recording low frequency oscillations from the perilesional region of the subject; and delivering current stimulation to the brain of the subject.

Abstract: Provided is a sensor system which can detect a thickness reduction, a crack, or the like of a pipe or a container covered with a thick coating member through ultrasonic inspection without attachment and detachment of the coating member. A sensor system used for nondestructive inspection includes a sensor attached to a surface of an inspection target, a sensor coil that is electrically connected to the sensor via a first cable, a first electromagnetic wave blocking member that is disposed between the surface of the inspection target and the sensor coil, a sensor side coil that is disposed to face the sensor coil with a gap and is coupled to the sensor coil through electromagnetic induction, and a probe side coil that is disposed to be separated from the sensor side coil and is electrically connected to the sensor side coil via a second cable.

Abstract: The application relates to a reservoir chip and a method for producing the same. The method includes: scanning a three-dimensional structure of a real oil reservoir core and reconstructing the three-dimensional structure, extracting pore size distribution characteristics, analyzing formation of a pore structure of the real oil reservoir core and accumulation morphology of rock particles, extracting the morphology of main large particles in the rock particles and establishing a large particle morphology database; distributing and projecting particles in a porous medium of the reservoir chip, to obtain a picture of the reservoir chip structure; importing the picture into a drawing software, and drawing import and export regions of the reservoir chip structure to obtain a design drawing of the reservoir chip; and making the design drawing etched on a substrate and bonded with a heat-resistant glass anode to obtain the reservoir chip.

Abstract: A clock and data recovery (CDR) device includes a data sampler configured to output a data signal by sampling an input signal according to a first clock signal; an edge sampler configured to output an edge signal by sampling the input signal according to a second clock signal, the second clock signal having substantially the same frequency as the first clock signal and having substantially an opposite phase to the first clock signal; an error detection circuit configured to identify a plurality of patterns based on the data signal and the edged signal and generate an error signal according to occurrence frequencies of the identified plurality of patterns; and an oscillation control circuit configured to generate a first oscillation control signal to control an oscillator generating the first and second clock signal according to the error signal.

Abstract: Mixed allergen compositions of one, two or more different allergens are provided. In some instances, the mixed allergen compositions include: a nut allergen; an animal allergen; and at least one of: a non-nut plant allergen; a biotic agent; and a vitamin. Also provided are methods of administering the mixed allergen compositions to a subject. The mixed allergen compositions find use in a variety of applications, including health maintenance, immune balance, gut balance, immune support, health improvement and therapeutic applications.

Abstract: A geothermal heat utilization system includes a well that includes an upper opening, a lower opening, a water chamber capable of storing underground water inside, and a pump provided inside the water chamber and capable of pumping underground water; and a water suction pipe that extends from the pump toward a heat exchanger, wherein the water chamber includes an upper suction valve capable of being opened and closed toward the upper opening and a lower suction valve capable of being opened and closed toward the lower opening, and wherein the geothermal heat utilization system is configured such that, when any one of the upper suction valve and the lower suction valve is opened, the other is closed.

Abstract: A method for testing ecotoxicity of disinfection by-products (DBPs) is disclosed, including the following steps: firstly, hatching and culturing a brine shrimp to obtain a second-instar brine shrimp larvae; secondly, putting the brine shrimp larvae into a water sample containing the DBPs, obtaining a survival rate through acute toxicity exposure and chronic toxicity exposure, respectively, to calculate the toxicity of the water sample to brine shrimp. The new method includes both acute and chronic toxicity tests. The test water sample can be either a single substance solution or an actual disinfection water sample. The brine shrimp has high sensitivity and is convenient to hatch and culture. The raw materials are inexpensive and easily available. The requirements for the culture environment are not high, and the toxicity end-point is clear. The new method is simple, sensitive and economical, and therefore, a popularization is feasible in sewage and reuse water plants.

Abstract: Provided are transgenic organisms, such as plants and plant parts, cells, and related compositions and methods for producing and monitoring the genotype for enhanced production of montbretin A and/or its precursors. For example, provided is a transgenic organism comprising at least one heterologous nucleic acid operatively linked to a promoter, wherein the heterologous nucleic acid encodes at least one enzyme in a montbretin A (MbA) metabolic pathway. The organisms can be a plant, plant part, or plant cell, or a microorganism such as a yeast. Also provided is a method for producing at least one montbretin A (MbA) precursor and/or MbA, comprising permitting the expression of the at least one heterologous nucleic acid in the transgenic organism. The disclosure also provides isolated nucleic acid molecules that comprise sequence encoding at least one enzyme in a montbretin A (MbA) metabolic pathway and vectors comprising the nucleic acids.

Abstract: An apparatus, and method of operating the same, include a system for indoor positioning and localization. The apparatus includes a first beacon having a beacon optical detector to receive an optical signal, and a beacon microcontroller. The apparatus includes a zone-positioning unit (ZPU) having an optical source configured to transmit the optical signal, and a ZPU microcontroller. The beacon microcontroller is configured to identify and decode the optical signal after receipt by the beacon optical detector to determine data related to a position of the ZPU. The beacon microcontroller is further configured to wirelessly communicate with the ZPU microcontroller to convey information to the ZPU including the data related to a position of the ZPU and a known position of the first beacon. The ZPU microcontroller is configured to determine a position of the ZPU based on the information received from the first beacon.

Abstract: The present application discloses a method and a system for person re-identification, the method including: inputting a training set to a model-to-be-trained, and determining a single-class label and memory features of each image data in the training set; determining multi-class labels through positive label prediction according to the single-class labels and a memory feature set; determining classification scores according to image features of each image data in the training set and the memory feature set; determining a multi-label classification loss according to the multi-class labels and the classification scores; and updating and training the model-to-be-trained to obtain a re-identification model according to the multi-label classification loss.

Abstract: This present disclosure relates to the use of one or more biomarkers for diagnosis, screening, or monitoring aortic aneurysm disease (e.g., ascending aortic aneurysm, descending thoracic aortic aneurysm, abdominal aortic aneurysm and Marfan syndrome) in a biological sample (e.g., a blood sample) of a subject. Accordingly, this disclosure provides methods and kits for determining the presence of one or more biomarkers for aortic aneurysm disease in a biological sample of a subject; methods for using the presence of such biomarkers to predict or diagnose aortic aneurysm disease in a subject; and methods to select or modify a therapeutic regimen (e.g., a beta-blocker treatment) for a subject based on the use of such biomarkers.

Abstract: The invention discloses a base station and a modulation method supporting lattice-partition-based downlink non-orthogonal multiple access. The modulation method includes: modulating at least one most significant bit (MSB) of weak user equipment (UE) into a first signal with first transmission power; modulating at least one least significant bit (LSB) of the weak UE into a second signal with second transmission power, where the second transmission power is less than the first transmission power; and modulating at least one second MSB of strong UE into a third signal with third transmission power, where the third transmission power is between the first transmission power and the second transmission power.

Abstract: The present invention relates to a method for chemical production of 3,6-anhydro-L-galactitol (L-AHGoI), which is a novel sugar alcohol, and agarobititol (ABol), which is a disaccharide having the same agarobititol as a reductant end thereof, from sea algae.

Abstract: A new and distinct interspecific hybrid Corylus plant named ‘OSU 541.147’ characterized by a vigorous, upright growth habit, the production of nuts with round kernels that fall free of the husk at maturity, and resistance to eastern filbert blight caused by the fungus Anisogramma anomala (Peck) E. Müller.