Patents Assigned to University
  • Patent number: 12285627
    Abstract: A novel treatment method is disclosed, wherein a patch configured to be placed on a patient's skin is activated, before placement, to deliver localized radiotherapy to a diseased area of the skin. The disclosed devices and methods minimize or prevent collateral damage to the neighboring tissues. In most cases, the disclosed devices and methods include coating a contoured, solid, flexible or conformal substrate with one or more lanthanide elements and then activating (e.g. neutron irradiation) the elements such that its resulting radioisotope emits beta-particles into the diseased skin surface when applied to the patient's skin. Novel processes are described for fabricating and irradiating the lanthanide-based skin patch, for example a holmium-based skin patch.
    Type: Grant
    Filed: October 18, 2019
    Date of Patent: April 29, 2025
    Assignees: Colorado School of Mines, The Regents of the University of Colorado, A Body Corporate
    Inventors: Frédéric Sarazin, Jeramy Zimmerman, Rachel Morneau, Martin Ritter, David Westerly, Quentin Diot
  • Patent number: 12286352
    Abstract: Methods for the production of carbon-based and other nanostructures are provided.
    Type: Grant
    Filed: December 17, 2021
    Date of Patent: April 29, 2025
    Assignee: Rutgers, the State University of New Jersey
    Inventors: Stephen D. Tse, Hua Hong, Bernard H. Kear
  • Patent number: 12288905
    Abstract: An online observation method of an anode nitrogen concentration for a proton exchange membrane fuel cell is disclosed. Firstly, a dynamic model of anode nitrogen concentration is established based on a gas transmembrane penetration model and an anode material conservation model of a fuel cell, and then an average voltage degradation value between a nitrogen partial pressure and an average monolithic cell voltage is obtained as online feedback information, an online observer of anode nitrogen concentration is established based on the dynamic model of anode nitrogen concentration and the online feedback information, and the anode nitrogen concentration of the fuel cell is obtained by the online observer. The new method solves the problem of online observation of anode nitrogen concentration during the operation of a proton exchange membrane fuel cell engine system under dynamic conditions.
    Type: Grant
    Filed: June 29, 2020
    Date of Patent: April 29, 2025
    Assignee: ZHEJIANG UNIVERSITY
    Inventors: Jian Chen, Zhiyang Liu, Chizhou Yan
  • Patent number: 12286583
    Abstract: Provided are a polymer viscosity reducer for a water-based drilling fluid and a preparation method thereof. The polymer viscosity reducer for the water-based drilling fluid is prepared from raw materials including, in parts by mass: 100 parts to 150 parts of water, 30 parts to 50 parts of acrylic acid, 10 parts to 20 parts of maleic anhydride, 40 parts to 60 parts of allyl polyethylene glycol, 3 parts to 6 parts of an initiator, 1 part to 3 parts of a pH regulator, 10 parts to 20 parts of a diamine, and 5 parts to 10 parts of a saturated organic acid.
    Type: Grant
    Filed: May 28, 2024
    Date of Patent: April 29, 2025
    Assignee: YANGTZE UNIVERSITY
    Inventor: Fuchang You
  • Patent number: 12288986
    Abstract: A method and device for supporting weak networks in an AC/DC distribution network are provided. The method includes the following steps: constructing a topology of the AC/DC distribution network, where the topology is configured to support the weak networks and isolate faults actively, and the topology is a multi-terminal ring structure; establishing a distributed optimization method for the AC/DC distribution network based on the topology; obtaining power fluctuations of the AC/DC distribution network, where the AC/DC distribution network can switch a droop control mode automatically according to the power fluctuations; and obtaining frequency fluctuations of the AC/DC distribution network, where the AC/DC distribution network performs energy dispatching according to the frequency fluctuations to match the droop control mode of the AC/DC distribution network.
    Type: Grant
    Filed: October 22, 2024
    Date of Patent: April 29, 2025
    Assignee: Tianjin University
    Inventors: Qian Xiao, Wenbiao Lu, Hongjie Jia, Yunfei Mu, Yu Jin, Tianxiang Li, Yidi Zhu, Yansong Zhao, Huiqiao Liu, Xiaodan Yu
  • Patent number: 12286488
    Abstract: Disclosed is a hybridoma cell strain that secretes anti-dinitolmide monoclonal antibodies applicable to the field of food safety immunoassay methods. The hybridoma cell strain DAS3H10 that secretes anti-dinitolmide monoclonal antibodies has been deposited in Comprehensive Microbiology Center of China Microbial Culture Collection Management Committee (CGMCC), addressed in No. 1 Hospital No. 3 Institute of Microbiology of the Chinese Academy of Sciences, North Chenxi Road, Beijing Chaoyang District in Beijing. It is classified as a monoclonal cell strain. The deposit date is Nov. 28, 2019, and the deposit number is MCCC No. 19165. The monoclonal antibody secreted by the hybridoma cell strain DAS3H10 has a good affinity and high sensitivity to dinitolmide. Because of IC50 to dinitolmide up to 9.01 ng/mL, the monoclonal antibody could be used to prepare dinitolmide immunoassay kits and colloidal gold test strips, and can further provide a powerful means for detecting dinitolmide in animal-derived foods.
    Type: Grant
    Filed: July 6, 2021
    Date of Patent: April 29, 2025
    Assignee: JIANGNAN UNIVERSITY
    Inventors: Chuanlai Xu, Jie Liu, Hua Kuang, Liguang Xu, Maozhong Sun, Liqiang Liu, Xiaoling Wu, Changlong Hao, Shanshan Song, Yongming Hu, Qiankun Zheng
  • Patent number: 12287650
    Abstract: A line-following robot in an assembly line. The line-following robot includes a microcontroller, a camera connected to the microcontroller, disposed on a front of the line-following robot, and configured to collect line images, an Infrared (IR) sensor array connected to the microcontroller, disposed on the line-following robot, and oriented in a direction of travel of the line-following robot, a first wheel set and a second wheel set disposed opposite one another on opposing sides of a bottom of the line-following robot, and a battery. The microprocessor controls a motor speed of the line-following robot based on an upcoming assembly line by continuously capturing and processing the lines images using an advance image processing technique and computer vision techniques.
    Type: Grant
    Filed: December 2, 2024
    Date of Patent: April 29, 2025
    Assignee: IMAM MOHAMMAD IBN SAUD ISLAMIC UNIVERSITY
    Inventors: Abdul Khader Jilani Saudagar, Safkat Shahrier Swapnil, Sandip Kumer Sarker, Arpon Bose Dibya, Md Tanvir Islam, Md. Abu-Talha Roni, Hitoun A. Alsagri, Khan Muhammad
  • Patent number: 12287326
    Abstract: Two rhodamine reversible fluorescent sensor derivatives, L1 and L2, bearing 2-methoxy-1-naphthaldehyde and 5-bromo-3-methoxy salicylaldehyde units were synthesized using microwave-assisted organic synthesis and used for selective and sensitive reversible sequential fluorescence detection of aluminum ion (Al3+) and azide (N3?) in aqueous acetonitrile solution via the fluorescence spectral changes. Stoichiometry and binding mechanisms for both sensors are well characterized and established by the respective spectroscopic techniques. L1 and L2 sensors are useful for the analysis of Al3+ and N3? in environmental samples and biological studies.
    Type: Grant
    Filed: April 12, 2023
    Date of Patent: April 29, 2025
    Assignee: Morgan State University
    Inventor: Fasil Abebe
  • Patent number: 12287361
    Abstract: Disclosed are a power transmission line monitoring system and a power transmission line monitoring method. The monitoring method comprises: acquiring, by means of a functional node, monitoring data related to a power transmission line, and transmitting the monitoring data to an edge node; and receiving the monitoring data by means of the edge node, transmitting the monitoring data to a collection node by means of an edge node chain type communication network, and sending, by the collection node, the data to a master station server. In the application, a self-organized edge node chain type network is formed by means of edge nodes, and data transmission is performed by means of the edge node chain type network, so that problem of poor data transmission caused by impossible coverage of a cellular network can be solved.
    Type: Grant
    Filed: April 27, 2023
    Date of Patent: April 29, 2025
    Assignees: TSINGHUA UNIVERSITY, SICHUAN ENERGY INTERNET RESEARCH INSTITUTE, TSINGHUA UNIVERSITY
    Inventors: Jinliang He, Jun Hu, Yong Ouyang, Yi Liu, Shanxiang Wang, Rong Zeng, Zhanqing Yu
  • Patent number: 12289449
    Abstract: The present invention relates to a method and apparatus for encoding and decoding a video image based on transform. The method for decoding a video includes: determining a transform mode of a current block; inverse-transforming residual data of the current block according to the transform mode of the current block; and rearranging the inverse-transformed residual data of the current block according to the transform mode of the current block, wherein the transform mode includes at least one of SDST (Shuffling Discrete Sine Transform), SDCT (Shuffling Discrete cosine Transform), DST (Discrete Sine Transform) or DCT (Discrete Cosine Transform).
    Type: Grant
    Filed: July 26, 2023
    Date of Patent: April 29, 2025
    Assignees: Electronics and Telecommunications Research Institute, Industry Academy Cooperation Foundation of Sejong University
    Inventors: Sung Chang Lim, Jung Won Kang, Hyun Suk Ko, Jin Ho Lee, Ha Hyun Lee, Dong San Jun, Seung Hyun Cho, Hui Yong Kim, Jin Soo Choi, Yung Lyul Lee, Nam Uk Kim, Jun Woo Choi
  • Patent number: 12285399
    Abstract: When used as an active ingredient, bornyl acetate or a pharmaceutically acceptable salt thereof according to the present invention exhibits the effects of alleviating behavioral scales in an animal model, inhibiting the activation of microglia and the generation of inflammatory factors (COX-2 and iNOS), and lowering nerve excitability for responsiveness to cell-neural stimuli. Thus, bornyl acetate or a pharmaceutically acceptable salt thereof is found to have an excellent stress modulating potential and to be useful for the prevention and treatment of stress-related diseases, especially, depression, thereby finding advantageous applications in related industries.
    Type: Grant
    Filed: March 18, 2020
    Date of Patent: April 29, 2025
    Assignee: UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY
    Inventors: Ik-Hyun Cho, Jong-Hee Choi
  • Patent number: 12285013
    Abstract: The present invention relates to a processing method for increasing seed production rate of seed fruits of Cucumis sativus L., comprising the following steps: (1) preparing a plant growth regulator according to a formula proportion; (2) selecting seed fruits of Cucumis sativus L. growing naturally in a greenhouse and reaching a pollination stage, and dipping female flowers thereof with the plant growth regulator prepared in step (1) before pollination; (3) picking male flowers for pollination after the female flowers are completely dry; (4) dipping the pollinated female flowers again; (5) conducting field routine cultivation management. The present invention uses a DNA methyltransferase inhibitor “5-azacytidine” (C8H12N4O5) to treat the seed fruits of Cucumis sativus L. by soaking and dipping, wherein 5-azacytidine increases seed production efficiency by reducing fruit length of the seed fruits, reducing fruit weight and reducing nutrient loss for fruit growth.
    Type: Grant
    Filed: August 27, 2024
    Date of Patent: April 29, 2025
    Assignee: Yangzhou University
    Inventors: Xiaodong Yang, Yizhuo Deng, Lili Zhang, Lei Qiu, Jieni Gu, Xuehao Chen
  • Patent number: 12286573
    Abstract: To provide an adhesive sheet, the sheet increasing manufacturing efficiency of products including an adhesive agent layer, while using the adhesive agent layer to which an electro-conductive organic polymer compound is added. An adhesive sheet for use in applying a wiring board to a surface onto which the wiring board is to be applied, the adhesive sheet is constituted by an adhesive agent layer including an electro-conductive organic polymer compound and an adhesive material; a first releasing sheet provided on front surface of the adhesive agent layer; and a second releasing sheet provided on a back surface corresponding to a back surface of the front surface in the adhesive agent layer.
    Type: Grant
    Filed: March 12, 2020
    Date of Patent: April 29, 2025
    Assignees: Mektec Corporation, Osaka University
    Inventors: Masayuki Iwase, Teppei Araki, Tsuyoshi Sekitani, Shusuke Yoshimoto
  • Patent number: 12286406
    Abstract: Disclosed herein are compounds which inhibit RIPK1, pharmaceutical compositions, and methods of treatment of RIPK1-mediated diseases, such as neurodegenerative disorders, inflammatory disorders, and cancer.
    Type: Grant
    Filed: July 20, 2023
    Date of Patent: April 29, 2025
    Assignee: Board of Regents, The University of Texas System
    Inventors: Richard T. Lewis, Matthew Michael Hamilton, William J. Ray, Fernando Alvarez, Dana E. Pfaffinger, Naphtali Reyna, Jason Cross, Suyambu Kesava Vijayan Ramaswamy
  • Patent number: 12287324
    Abstract: The present invention includes a method for identifying a patient response to treatment for Alzheimer's Disease with a non-steroidal anti-inflammatory drug (NSAID) or an acetylcholinesterase (AChE) inhibitor drug comprising: obtaining a blood or serum sample from the patient; determining the presence of a proinflammatory endophenotype in the blood or serum sample of the patient; using the proinflammatory endophenotype to detect treatment response (a responder, a stable, a non-responder or an adverse responder); and treating the patient with the NSAID or the AChE inhibitor if the patient is in the responder or the stable treatment response phenotype group; or preventing a treatment with the NSAID or the AChE inhibitor if the patient is a non-responder or an adverse responder.
    Type: Grant
    Filed: January 14, 2019
    Date of Patent: April 29, 2025
    Assignee: University of North Texas Health Science Center At Fort Worth
    Inventor: Sid E. O'Bryant
  • Patent number: 12286645
    Abstract: The present disclosure generally relates to the method of generating human induced pluripotent stem cells (hiPSC) from patients with either heterozygous deletion of the FOX2A gene or GLUT2 (SLC2A2) gene mutations. The methods disclosed herein generate human cell models for diabetes, Fanconi Bickel Syndrome (FBS), dysmporphic features, growth hormone deficiency, central hypothyroidism, and related disorders. The methods disclosed herein generate patient-specific iPSC cell lines that could be used by researchers to perform mechanistic studies, drug screening, and understanding the role of GLUT2 or FOXA2 in specific human cell types.
    Type: Grant
    Filed: January 28, 2021
    Date of Patent: April 29, 2025
    Assignee: HAMAD BIN KHALIFA UNIVERSITY
    Inventors: Essam M. Abdelalim, Ahmed K. Elsayed, Khalid Hussain
  • Patent number: 12288320
    Abstract: Described herein are systems and methods for imaging the top surface of a fuel pellet to observe the formation of radial cracks employing resistive heating to volumetrically heat the fuel pellet, but instead of passing the current axially through the pellet, electrodes were placed on the sides of a single pellet to pass the current transversely across the pellet allowing for an unobstructed view of the top surface of the pellet.
    Type: Grant
    Filed: October 21, 2021
    Date of Patent: April 29, 2025
    Assignee: University of South Carolina
    Inventors: Travis Knight, Sobhan Patnaik, Theodore Besmann, Elwyn Roberts
  • Patent number: 12288936
    Abstract: Disclosed is a method for fast automatic calibration of a phased array based on a residual neural network. A phase setting matrix is set and an amplitude and a phase of a array far-field complex signal are measured with a network analyzer to obtain an amplitude and phase vector of the array far-field complex signal. A real part, an imaginary part, and a magnitude of the far-field measured complex signal value are separated and normalized, and mapped to RGB three-channel image data. Datasets are automatically generated according to a preset amplitude-phase error range by a simulation software, the datasets are proportionally divided into a training set and a test set to be input into the residual neural network for training to obtain a calibration model. Measured data is input into the calibration model for automatic estimation of the amplitude-phase error of the phased array.
    Type: Grant
    Filed: December 20, 2024
    Date of Patent: April 29, 2025
    Assignees: ZHEJIANG UNIVERSITY, DONGHAI LABORATORY
    Inventors: Chunyi Song, Haotian Chen, Nayu Li, Zhiwei Xu, Xinhong Xie, Zixian Ma, Bing Lan
  • Patent number: 12288292
    Abstract: An automatic generation method for three-dimensional morphology of ruts in asphalt pavements comprises: constructing a standard rut cross-section representation model, classifying ruts, acquiring detection data of a rutted section of an asphalt pavement, selecting different rut cross-sections at equal intervals in a longitudinal direction of the pavement, denoising and smoothening the rut cross-sections, selecting feature points according to geometric fluctuation features of the rut cross-sections, connecting the feature points and fitting a cross-sectional curve based on an evolution law of rut deformation, and fusing multiple reconstructed rut cross-sections to realize automatic generation and visualization of three-dimensional morphology of a rut.
    Type: Grant
    Filed: November 24, 2022
    Date of Patent: April 29, 2025
    Assignee: Southeast University
    Inventors: Leilei Chen, Daoxie Chen, Yuxuan Liu, Zhendong Qian, Wei Li
  • Patent number: 12285406
    Abstract: A method of treating cancer in a subject in need thereof includes administering to the subject a therapeutically effective amount of the compound of formula (I) or a pharmaceutically acceptable salt thereof, where each of R1-R4, R5A-R7A, and R5B-R7B is independently selected from a hydrogen atom, a halogen atom, a nitro group, a cyano group, a hydroxyl group, an alkoxy group, an optionally substituted alkyl group, an optionally substituted cycloalkyl group, an optionally substituted arylalkyl group, and an optionally substituted aryl group.
    Type: Grant
    Filed: December 19, 2024
    Date of Patent: April 29, 2025
    Assignee: IMAM MOHAMMAD IBN SAUD ISLAMIC UNIVERSITY
    Inventors: Tarek Ahmed Yousef, Saad Shaaban, Ahmed A. Al-Karmalawy, Ayman Abo Elmaaty, Marwa Sharaky