Abstract: The device for powdering a solid unit dosage form of medication and administering the powder form includes an applicator, a powdering tool and, in certain embodiments, a cap. The device is used to create a powder form from a solid unit dosage form, and then administer the powder form to a body cavity of a patient. The cap is provided with an integrated powdering tool, allowing an open end of an applicator barrel to be releasably covered thereby. Manipulation of the powdering tool creates the powder form through abrasion of a solid unit dosage form of the medication received within the barrel. The cap and powdering tool may then be removed, leaving the powder form of the solid unit dosage form to be administered to the body cavity, such as a patient's vagina or rectum.
Abstract: A laser-plasma-based acceleration system includes a focusing element and a laser pulse emission directing a laser beam to the focusing element to such that laser pulses transform into a focused beam and a chamber defining a nozzle having a throat and an exit orifice, emitting a critical density range gas jet from the exit orifice for laser wavelengths ranging from ultraviolet to the mid-infrared. the critical density range gas jet intersects the focused beam at an angle and in proximity to the exit orifice of the nozzle to define a point of intersection between the focused beam and the critical density range gas jet. In intersection with the critical density range gas jet, the pulsed focused beam drives a laser plasma wakefield relativistic electron beam. A corresponding method of laser-plasma-based acceleration is also described. The critical density range may include 2×1020 cm?3 to 5×1021 cm?3.
Type:
Grant
Filed:
May 15, 2017
Date of Patent:
December 31, 2019
Assignee:
University of Maryland, College Park
Inventors:
Howard M. Milchberg, Andrew Goers, George Hine, Fatholah Salehi, Linus Feder, Bo Miao
Abstract: Provided is a novel method of suppressing non-specific protein adsorption. The above-mentioned object can be achieved by treating a solid phase with a solid phase-treating liquid containing a phosphorylcholine group-containing polymer as a main component, and treating a specimen with a specimen-treating liquid containing, as a main component, a polymer having a phosphorylcholine group, a hydroxy group, and a hydrophobic group, followed by addition of the treated specimen to the treated solid phase.
Type:
Grant
Filed:
February 18, 2016
Date of Patent:
December 31, 2019
Assignees:
National University Corporation Kyoto Institute of Technology, NOF Corporation
Abstract: The present disclosure is directed to antibodies that bind to DC-HIL on the surface of myeloid-derived suppressor cells, and thus antagonize the T cell suppressor function of these cells, as well as their use in diagnosing and treating cancers such as melanoma.
Type:
Grant
Filed:
March 9, 2016
Date of Patent:
December 31, 2019
Assignee:
The Board of Regents of the University of Texas System
Abstract: A method and apparatus is provided to generate a multiresolution image having at least two regions with different pixel pitches. The multiresolution image is reconstructed using projection data having various pixel pitches corresponding to the pixel pitches of the multiresolution image. By using a higher resolution inside regions of interest (ROIs) in both the image and projection domains and lower resolution outside the ROIs, fast image reconstruction can be performed while avoiding truncation artifacts, which result imaging is limited to an ROI excluding attenuation regions. Further, those regions of greater clinical relevance and greater structural variance within the reconstructed images can be selected to be within the ROIs to improve the clinical benefit of the multiresolution image. The multiresolution image can be reconstructed using an iterative reconstruction method in which the high- and low-resolution regions are uniquely evaluated.
Type:
Grant
Filed:
September 13, 2017
Date of Patent:
December 31, 2019
Assignees:
The University of Chicago, Canon Medical Systems Corporation
Inventors:
Xiaochuan Pan, Zheng Zhang, Dan Xia, Yu-Bing Chang, Joseph Manak
Abstract: A device for generating bubbles, comprising a porous material having at least one hydrophilic surface (1), arranged such that a liquid (7) in which the bubbles (6) are intended to be formed may contact the hydrophilic surface (1) and at least one hydrophobic surface (2), arranged such that a gas (5) used to generate the bubbles (6) may flow past the hydrophobic surface (2) before it flows past the hydrophilic surface (1). The device may be used for creating fine bubbles in numerous applications, such as wastewater treatment, plant cultivation, aquafarming, aeration systems, bioreactors, fermeters, oil extraction or fuel cells.
Abstract: Devices having multiple multicomponent emissive layers are provided, where each multicomponent EML includes at least three components. Each of the components in each EML is a host material or an emitter. The devices have improved color stability and relatively high luminance.
Type:
Grant
Filed:
May 8, 2017
Date of Patent:
December 31, 2019
Assignee:
Universal Display Corporation
Inventors:
Vadim Adamovich, Michael Stuart Weaver, Nicholas J. Thompson
Abstract: The present invention provides for compositions and methods for producing sorghum crop plants that are resistant to herbicides. In particular, the present invention provides for sorghum plants, plant tissues and plant seeds that contain altered acetolactate synthase (ALS) genes and proteins that are resistant to inhibition by herbicides that normally inhibit the activity of the ALS protein.
Type:
Grant
Filed:
December 6, 2007
Date of Patent:
December 31, 2019
Assignee:
Kansas State University Research Foundation
Abstract: A catalyst is provided for the two electron reduction of oxygen. The catalyst can be reversible or near-reversible. The catalyst comprises a gold and a cobalt coordination complex, i.e., N,N?-bis(salicylidene)ethylene-diaminocobalt (II) (cobalt salen) or a derivative thereof. The cobalt coordination complex can be polymerized to form a film, for example, via electropolymerization, to cover a gold surface. Also provided are metal-air batteries, fuel cells, and air electrodes that comprise the catalyst, as well as methods of using the catalyst, for example, to reduce oxygen and/or produce hydrogen peroxide.
Type:
Grant
Filed:
November 3, 2014
Date of Patent:
December 31, 2019
Assignee:
University of Tennessee Research Foundation
Inventors:
Ming Qi, Thomas Zawodzinski, Shane Foister
Abstract: A bonded structure includes a first fiber part (12) and a second fiber part (14) arranged between a first member (10) and a second member (20). The first fiber part (12) and the second fiber part (14) are bonded so as to connect the first member (10) and the second member (20) to each other. The first fiber part (12) and the second fiber part (14) are arranged so that the fibers constituting the first fiber part (12) and the second fiber part (14) are oriented in a direction from the first member (10) toward the second member (20).
Abstract: The present disclosure is directed to a method of treating morphine tolerance and/or symptoms associated therewith by administration to a subject in need thereof a DN-TNF polypeptide that inhibits the activity of soluble TNF- but not transmembrane TNF-?.
Type:
Grant
Filed:
June 13, 2016
Date of Patent:
December 31, 2019
Assignee:
Georgia State University Research Foundation, Inc.
Abstract: The present invention relates to a method for incorporating dye and/or nanoparticles into polymer films and into electrospun polymeric nanofibers, and, more specifically, to a method for electrospinning a molecularly homogenous solution of dye (and/or nanoparticles) and polymer dissolved in a mutual solvent leading to uniform distribution of dye across the cross-section of each constituent fiber and to resulting nanofibers with the dye/nanoparticles incorporated therein.
Type:
Grant
Filed:
April 3, 2014
Date of Patent:
December 31, 2019
Assignee:
Syracuse University
Inventors:
Patrick T. Mather, Amir Torbati, Ryan Mather
Abstract: The present invention relates to a 5th-generation (5G) or pre-5G communication system which is provided for supporting a higher data transfer rate after a 4th-generation (4G) communication system such as a long term evolution (LTE). The present invention provides a method for selecting, by an access point (AP), a beam in a communication system supporting a beamforming scheme, the method comprising: a step of transmitting information which indicates whether or not a duplicated beacon transmission interval (BTI) is operated; and a step of performing a transmit sector sweep (TXSS) process at least twice during the duplicated BTI.
Type:
Grant
Filed:
September 23, 2016
Date of Patent:
December 31, 2019
Assignees:
Samsung Electronics Co., Ltd., Korea University Research and Business Foundation
Inventors:
Inkyu Lee, Jong-Ho Oh, Bong-Jin Kim, Tae-Yeong Kim, Min-Ki Ahn, Tae-Seok Oh, Seok-Ju Jang
Abstract: The present invention pertains to an antiviral drug for severe fever with thrombocytopenia syndrome, which contains a compound represented by formula (I) or a salt thereof, or a solvate of the compound or salt (In the formula, R1 and R2 are the same or different from each other, and each represents a substituted or unsubstituted C1-10 alkyl group, R1 and R2 may form a substituted or unsubstituted 5- or 6-member ring in conjunction with an adjacent nitrogen atom, and X represent a halogen atom.
Abstract: A method of acidizing a subterranean geological formation by injecting an emulsified acid into a wellbore, wherein the emulsified acid includes at least an aqueous phase comprising a hydrochloric acid solution, an oil phase comprising waste oil, and an emulsifier, and wherein the waste oil contains 45-75% by weight of aromatic compounds and preferably contains less than 0.5% by weight of non-hydrocarbon compounds. Various embodiments, and combinations of embodiments, of the emulsified acid and the method of acidizing are provided.
Type:
Application
Filed:
September 9, 2019
Publication date:
December 26, 2019
Applicant:
King Fahd University of Petroleum and Minerals
Abstract: A method and apparatus for predictive coding of spherical or 360-degree video with dynamics dominated by camera motion. To achieve efficient compression, a geodesic translation motion model is introduced to characterize the perceived motion of objects on the sphere. Pixels in the surrounding objects are perceived as translating on the sphere along their respective geodesics, which intersect at the two points where a line, determined by the motions of the camera and surrounding objects, intersects the sphere. This motion compensation perfectly models the perceived motion on the sphere, and accounts for perspective distortions due to camera and object motions. Experimental results demonstrate that the preferred embodiments of the present invention achieve significant performance gains over prevalent motion-compensated prediction techniques, across various projection geometries.
Type:
Application
Filed:
June 20, 2019
Publication date:
December 26, 2019
Applicant:
The Regents of the University of California
Abstract: An artificial joint includes a first joint assembly and a second joint assembly. The first joint assembly is adapted to be connected to a first bone and has a first contacting surface, wherein the first contacting surface includes a first convex arc surface, a second convex arc surface, and a third convex arc surface. The second joint assembly is adapted to be connected to a second bone and has a second contacting surface, wherein the second contacting surface is in contact with the first contacting surface and includes a first concave arc surface, a second concave arc surface, and a third concave arc surface, and the first concave arc surface, the second concave arc surface, and the third concave arc surface respectively correspond to the first convex arc surface, the second convex arc surface, and the third convex arc surface.
Type:
Application
Filed:
December 19, 2018
Publication date:
December 26, 2019
Applicants:
Industrial Technology Research Institute, National Taiwan University Hospital
Abstract: The present disclosure provides compositions and methods for the treatment or prophylaxis of a perfusion disorder, such as ischemia and/or reperfusion injury, in a subject's organ, tissue or extremity by preserving or improving endothelial function, reducing vascular injury, and/or promoting vascular repair. The disclosed compositions comprise endothelial colony-forming cells or a serum-free composition comprising chemically defined media conditioned by endothelial colony-forming cells.
Type:
Application
Filed:
February 21, 2018
Publication date:
December 26, 2019
Applicant:
Indiana University Research and Technology Corporation
Abstract: A system and method of treating hyperacusis is presented. The system uses a customizable, patient-specific, in-ear device combining sound attenuation with loudness suppression and a noise generator to expand the dynamic range of a patient. This device is used with novel software and counseling to provide a patient-specific treatment to hypersensitivity to sound.
Type:
Application
Filed:
June 24, 2019
Publication date:
December 26, 2019
Applicants:
University of South Florida, The Board of Trustees of the University of Alabama, SoundsGood Labs, Inc.
Inventors:
David Alan Eddins, Charles Craig Formby, Stephen W. Armstrong