Patents Assigned to University
  • TREATMENT OF DRUG RESISTANT PROLIFERATIVE DISEASES WITH TELOMERASE MEDIATED TELOMERE ALTERING COMPOUNDS
    Publication number: 20190388453
    Abstract: The described invention is directed toward pharmaceutical compositions and methods of using 6-mercaptopurine ribosides and analogues thereof for the treatement of cancer and other hyperproliferative diseases. The described compounds can be converted into telomere substrates in vivo and can be recognized by telomerase for incorporation into telomeres of telomerase active cells, leading to induction of cell death of the telomerase active cells.
    Type: Application
    Filed: June 24, 2019
    Publication date: December 26, 2019
    Applicant: The Board of Regents of the University of Texas System
    Inventors: Jerry SHAY, Ilgen MENDER, Kimberly BATTEN
  • PATCH GRAFT COMPOSITIONS FOR CELL ENGRAFTMENT
    Publication number: 20190388584
    Abstract: Compositions and methods of transplanting cells by grafting strategies into solid organs (especially internal organs) are provided. These methods and compositions can be used to repair diseased organs or to establish models of disease states in experimental hosts. The method involves attachment onto the surface of a tissue or organ, a patch graft, containing the donor cells. The donor cells may be a mixture of stem cells/progenitors with supporting early lineage stage mesenchymal cells. The patch graft promotes migration of the donor cells into the host organ and supports the successful integration of donor cells with host cells to repair the diseased organ.
    Type: Application
    Filed: May 24, 2019
    Publication date: December 26, 2019
    Applicant: The University of North Carolina at Chapel Hill
    Inventors: Lola M. Reid, Wencheng Zhang, Eliane Wauthier
  • IMAGE ENCODING METHOD/DEVICE, IMAGE DECODING METHOD/DEVICE, AND RECORDING MEDIUM IN WHICH BITSTREAM IS STORED
    Publication number: 20190394465
    Abstract: The present invention provides an image encoding method and an image decoding method. The image encoding method of the present invention comprises: a first dividing step of dividing a current image into a plurality of blocks; and a second dividing step of dividing, into a plurality of sub blocks, a block, which is to be divided and includes a boundary of the current image, among the plurality of blocks, wherein the second dividing step is recursively performed by setting a sub block including the boundary of the current images as the block to be divided, until the sub block including the boundary of the current image does not exist among the sub blocks.
    Type: Application
    Filed: October 12, 2017
    Publication date: December 26, 2019
    Applicant: Industry Academy Cooperation Foundation of Sejong University
    Inventors: Joo Hee MOON, Sung Won LIM, Dong Jae WON
  • TRANSDERMAL BIOSENSOR
    Publication number: 20190388016
    Abstract: The disclosed technology includes device, systems, and methods for detecting an analyte using a biosensor. In some implementations, the biosensor may be a transdermal biosensor including a housing material, a nanocellulose material disposed within the housing material, an enzyme entrapped within the nanocellulose material that produces a chemical or biological product when exposed to a vapor or liquid, and a luminescent material within the nanocellulose material that emits visible light upon a chemical or biological reaction with the chemical or biological product.
    Type: Application
    Filed: June 21, 2019
    Publication date: December 26, 2019
    Applicant: The Regents of the University of Colorado, a Body Corporate
    Inventors: Stephen Michael LEWIS, Andrew John HENDERSON, Jenny B. FILIPETTI
  • FUNCTIONALIZED PYRANO[2,3-D]PYRIMIDIN-7-ONE DERIVATIVES AND METHODS FOR THEIR PREPARATION AND USE
    Publication number: 20190389874
    Abstract: Functionalized pyrano[2,3-d]pyrimidin-7-one derivatives, methods for making the derivatives, and methods of using the derivatives as protein kinase inhibitors.
    Type: Application
    Filed: May 23, 2017
    Publication date: December 26, 2019
    Applicant: The Texas A&M University System
    Inventors: Dai Lu, Chang-Jiang Qiao, Boqiao Fu, Anantha Lakshmi Duddupudi, Zhixing Wu
  • METHOD OF EMULSIFYING AN ACID AND ACIDIZING A GEOLOGICAL FORMATION
    Publication number: 20190390103
    Abstract: A method of acidizing a subterranean geological formation by injecting an emulsified acid into a wellbore, wherein the emulsified acid includes at least an aqueous phase comprising a hydrochloric acid solution, an oil phase comprising waste oil, and an emulsifier, and wherein the waste oil contains 45-75% by weight of aromatic compounds and preferably contains less than 0.5% by weight of non-hydrocarbon compounds. Various embodiments, and combinations of embodiments, of the emulsified acid and the method of acidizing are provided.
    Type: Application
    Filed: September 9, 2019
    Publication date: December 26, 2019
    Applicant: King Fahd University of Petroleum and Minerals
    Inventors: Abdullah S. SULTAN, Ziad SIDAOUI
  • METHOD FOR DRILLING A SUBTERRANEAN GEOLOGICAL FORMATION
    Publication number: 20190390105
    Abstract: A method of acidizing a subterranean geological formation by injecting an emulsified acid into a wellbore, wherein the emulsified acid includes at least an aqueous phase comprising a hydrochloric acid solution, an oil phase comprising waste oil, and an emulsifier, and wherein the waste oil contains 45-75% by weight of aromatic compounds and preferably contains less than 0.5% by weight of non-hydrocarbon compounds. Various embodiments, and combinations of embodiments, of the emulsified acid and the method of acidizing are provided.
    Type: Application
    Filed: September 9, 2019
    Publication date: December 26, 2019
    Applicant: King Fahd University of Petroleum and Minerals
    Inventors: Abdullah S. SULTAN, Ziad SIDAOUI
  • ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES
    Publication number: 20190390108
    Abstract: Novel Iridium complexes having three different bidentate ligands useful for phosphorescent emitters in OLEDs are disclosed. At least one of the three different bidentate ligands is a carbene ligand.
    Type: Application
    Filed: September 7, 2019
    Publication date: December 26, 2019
    Applicant: Universal Display Corporation
    Inventors: Jui-Yi TSAI, Chuanjun XIA, Chun LIN, Adrian U. PALACIOS, Enrique OÑATE, Miguel A. Esteruelas, Pierre-Luc T. BOUDREAULT, Sonia BAJO, Montserrat OLIVÁN
  • ENGINEERED PRIMATE L-METHIONINASE FOR THERAPEUTIC PURPOSES
    Publication number: 20190390187
    Abstract: Methods and compositions relating to the engineering of an improved protein with methionine-?-lyase enzyme activity are described. For example, in certain aspects there may be disclosed a modified cystathionine-?-lyase (CGL) comprising one or more amino acid substitutions and capable of degrading methionine. Furthermore, certain aspects of the invention provide compositions and methods for the treatment of cancer with methionine depletion using the disclosed proteins or nucleic acids.
    Type: Application
    Filed: February 1, 2019
    Publication date: December 26, 2019
    Applicant: Board of Regents, The University of Texas System
    Inventors: George Georgiou, Everett Stone, Wei-Cheng Lu
  • DNA SEQUENCING WITH NON-FLUORESCENT NUCLEOTIDE REVERSIBLE TERMINATORS AND CLEAVABLE LABEL MODIFIED NUCLEOTIDE TERMINATORS
    Publication number: 20190390271
    Abstract: This invention provides a process for sequencing nucleic acids using 3? modified deoxynucleotide analogues or 3? modified deoxyinosine triphosphate analogues, and 3? modified dideoxynucleotide analogues having a detectable marker attached thereto.
    Type: Application
    Filed: April 15, 2019
    Publication date: December 26, 2019
    Applicant: The Trustees of Columbia University in the City of New York
    Inventors: Jingyue Ju, Dae Hyun Kim, Jia Guo, Qinglin Meng, Zengmin Li, Huanyan Cao
  • SPINE IMAGE REGISTRATION METHOD
    Publication number: 20190392552
    Abstract: A spine image registration method includes: obtaining a CT image and an MRI image corresponding to a spine; inputting the CT image into a first model to identify at least one first vertebral body of the spine in the CT image; inputting the MRI image to a second model to identify at least one second vertebral body of the spine in the MRI image; marking the first vertebral body with at least one first landmark and marking the second vertebral body with at least one second landmark; matching the first landmark with the second landmark to obtain a corresponding relationship; performing a registration on the CT image and the MRI image according to the corresponding relationship, and generating a registered image according to the content of the CT image and the content of the MRI image located in the same coordinate space; and outputting the registered image.
    Type: Application
    Filed: August 23, 2018
    Publication date: December 26, 2019
    Applicant: National Taiwan University of Science and Technology
    Inventors: Ching-Wei Wang, Hsin-Ya Ko
  • BIOMARKERS FOR THE DIAGNOSIS OF LACUNAR STROKE
    Publication number: 20190390276
    Abstract: This invention provides gene expression profiles useful for diagnosing lacunar stroke and for distinguishing lacunar stroke from non-lacunar stroke.
    Type: Application
    Filed: December 20, 2018
    Publication date: December 26, 2019
    Applicant: The Regents of the University of California
    Inventors: Frank Sharp, Glen C. Jickling
  • REDUCTION OF LIPASE ACTIVITY IN PRODUCT FORMULATIONS
    Publication number: 20190390203
    Abstract: The invention relates a method for producing a stable recombinant protein, comprising growing a non-naturally occurring host cell in a culture medium to produce a recombinant protein, and making a composition comprising the recombinant protein and a polysorbate. The production of endogenous lipoprotein lipase by the host cell is reduced. The endogenous lipoprotein lipase is present in the composition in a small amount, and is capable of degrading the polysorbate. The invention also relates to the relevant host cells and compositions, and preparation thereof.
    Type: Application
    Filed: September 10, 2019
    Publication date: December 26, 2019
    Applicant: University of Delaware
    Inventors: Kelvin LEE, Abraham Lenhoff, Kristin Valente, Nick Levy, Yatin Gokarn
  • ION CONCENTRATION DISTRIBUTION MEASURING DEVICE
    Publication number: 20190391110
    Abstract: An ion concentration distribution measurement device includes a unit detection element for outputting charges of an amount according to an ion concentration, and an integration circuit for outputting a signal value according to the amount of charges which are output from the unit detection element. The unit detection element includes a MOS transistor, an ion sensitive portion, a first capacitive portion, and a transfer switch. The integration circuit includes an amplifier, a second capacitive portion, and a reset switch.
    Type: Application
    Filed: February 8, 2018
    Publication date: December 26, 2019
    Applicants: National University Corporation TOYOHASHI UNIVERSITY OF TECHNOLOGY, HAMAMATSU PHOTONICS K.K.
    Inventors: Kazuaki SAWADA, Hiroo YAMAMOTO, Seiichiro MIZUNO, Toshiki WAKAMORI
  • METHOD OF PREPARING HYDROPHOBIC POROUS SILICA AND HYDROPHOBIC POROUS SILICA
    Publication number: 20190389732
    Abstract: A method of preparing hydrophobic porous silica includes reacting a porous silica particle containing a hydrophilic group in a solvent with an organosilane compound under a basic catalyst to form a mixture, drying the mixture comprising the porous silica particle in a vacuum, and condensation reacting the hydrophilic group of the porous silica particle with the organosilane compound on the surface of the porous silica particle to modify the surface of the porous silica particle to be hydrophobic.
    Type: Application
    Filed: August 28, 2019
    Publication date: December 26, 2019
    Applicant: Research & Business Foundation Sungkyunkwan University
    Inventors: Jae Young CHOI, Su Dong CHAE, Jang Ho PARK, Sung Ho LEE
  • PEPTIDES FOR ANGIOGENIC THERAPY
    Publication number: 20190389922
    Abstract: Provided herein are compositions including peptide or nucleic acids encoding peptides and related methods for the treatment of angiogenic conditions such as cancer, vascular disorders such as cardiovascular disorders, and infectious disease.
    Type: Application
    Filed: January 25, 2019
    Publication date: December 26, 2019
    Applicant: The Regents of the University of California
    Inventor: Mira SASTRI
  • METHOD OF FORMING NITRIDE FILM
    Publication number: 20190390332
    Abstract: A method of forming a nitride film wherein (a) a silane-based gas is supplied to a processing chamber through a gas supply port; (b) a nitrogen radical gas from a radical generator is supplied to the processing chamber through a radical gas pass-through port; and (c) the silane-based gas supplied in (a) is reacted with the nitrogen radical gas supplied in (b), without causing a plasma phenomenon in the processing chamber, to form a nitride film on a wafer.
    Type: Application
    Filed: February 14, 2017
    Publication date: December 26, 2019
    Applicants: Toshiba Mitsubishi-Electric Industrial Systems Corporation, Tohoku University
    Inventors: Shinichi NISHIMURA, Kensuke WATANABE, Yoshihito YAMADA, Akinobu TERAMOTO, Tomoyuki SUWA, Yoshinobu SHIBA
  • ON-CHIP POWER SUPPLY NOISE SUPPRESSION THROUGH HYPERABRUPT JUNCTION VARACTORS
    Publication number: 20190393360
    Abstract: The increasing power density and, therefore, current consumption of high performance integrated circuits (ICs) results in increased challenges in the design of a reliable and efficient on-chip power delivery network. In particular, meeting the stringent on-chip impedance of the IC requires circuit and system techniques to mitigate high frequency noise that results due to resonance between the package inductance and the onchip capacitance. In this paper, a novel circuit technique is proposed to suppress high frequency noise through the use of a hyperabrupt junction tuning varactor diode as a decoupling capacitor for noise critical functional blocks. With the proposed circuit technique, the voltage droops and overshoots on the onchip power distribution network are suppressed by up to 60% as compared to MIM or deep trench decoupling capacitors of the same capacitance.
    Type: Application
    Filed: June 21, 2019
    Publication date: December 26, 2019
    Applicant: Drexel University
    Inventors: Divya Pathak, Ioannis Savidis
  • IMAGING AGENTS AND USES THEREOF
    Publication number: 20190388570
    Abstract: The present invention relates to various compositions and methods of using these compositions for imaging natriuretic peptide receptors using, for example, positron emission tomography.
    Type: Application
    Filed: June 21, 2019
    Publication date: December 26, 2019
    Applicant: Washington University
    Inventors: Yongjian Liu, Pamela K. Woodard
  • METHODS AND COMPOSITIONS OF CARNOSOL FOR INHIBITING UVB-INDUCED SKIN DAMAGE
    Publication number: 20190388389
    Abstract: Compositions and methods for inhibition UVB-irradiation damage by administering an effective amount of carnosol are described.
    Type: Application
    Filed: January 31, 2018
    Publication date: December 26, 2019
    Applicant: Ohio University
    Inventors: Shiyong Wu, Lingying Tong