Abstract: A system for testing thermal response time of an uncooled infrared focal plane detector array and a method therefor is provided. The system comprises: a blackbody, a chopper, a detector unit under test and a testing system. The method comprises: emitting radiation by the blackbody, chopping by the chopper, then radiating the radiation to the uncooled infrared focal plane detector array under test; generating different responses on the radiation at different chopping frequencies by the uncooled infrared focal plane detector array under test; collecting different response values of the uncooled infrared focal plane detector array under test at different chopping frequencies; obtaining response amplitude at a corresponding frequency in a frequency domain by FFT; fitting according to a formula Rv ? ( f ) = Rv ? ( 0 ) 1 + ( 2 ? ? ? ? f ? ? ? ) 2 to obtain the thermal response time.
Type:
Grant
Filed:
May 2, 2018
Date of Patent:
April 30, 2019
Assignee:
University of Electronic Science and Technology of China
Abstract: This invention provides a transistor device structure that incorporates a self-aligned doped contact formed by inserting a molecularly-thin layer of bonded anions between the semiconductor and the source-drain electrode array wherein the semiconductor is p-doped at the interface with the bonded-anion layer, and a method of making this structure using oxidant species incorporated into the molecularly-thin layer. The device shows ohmic hole injection and hole extraction at the contacts to give high-performance transistor characteristics with low contact resistance.
Type:
Grant
Filed:
February 1, 2016
Date of Patent:
April 30, 2019
Assignees:
BASF SE, National University of Singapore
Inventors:
Mi Zhou, Peter K.-H. Ho, Lay-Lay Chua, Png Rui-Qi, Wei-Ling Seah
Abstract: An imaging system includes an indicator installed around an antenna, wherein optical characteristics of the indicator change as a function of an electromagnetic field formed by the antenna, an imaging apparatus for imaging a change in optical characteristics of the indicator, a transmitter for radiating radio waves toward the antenna, and a receiver for receiving a signal from the antenna.
Type:
Grant
Filed:
December 20, 2016
Date of Patent:
April 30, 2019
Assignees:
Hyundai Motor Company, Sogang University Research Foundation
Inventors:
Sang Heun Lee, Sung-Hoon Jeon, Hanju Lee, Hyun-Wook Jang, Kiejin Lee, Do-Suck Han
Abstract: The present disclosure provides compositions and methods for treating bacterial infections in a subject. The methods comprise administering a compound that binds a FAD-dependent flavoenzyme and a tetracycline, analog, derivative, or pharmaceutically acceptable salt thereof.
Type:
Grant
Filed:
June 26, 2017
Date of Patent:
April 30, 2019
Assignee:
Washington University
Inventors:
Niraj Tolia, Gautam Dantas, Timothy Wencewicz, Jooyoung Park, Andrew Gasparrini, Kevin Forsberg, Joseph Vogel, Margaret Ruth Reck, Chanez Tiffany Symister, Jana L. Markley
Abstract: An ultrasonic communication system and method provide a networking framework for wearable devices based on ultrasonic communications. The ultrasonic communication system and method incorporate a set of physical, data link, network and application layer functionalities that can flexibly adapt to application and system requirements to efficiently distribute information between ultrasonic wearable devices.
Type:
Grant
Filed:
January 26, 2016
Date of Patent:
April 30, 2019
Assignee:
Northeastern University
Inventors:
Tommaso Melodia, Giuseppe Enrico Santagati
Abstract: Systems and methods for sensing target molecules such as redox reactive agents, comprising a sample compartment and a sensing compartment being in fluid communication, are disclosed. A sensing compartment which comprises nanostructures to which a functional moiety is covalently attached and which is such that upon contacting a redox reactive agent a change in electrical property of the nanostructure occurs, and integration of such a sensing compartment with sensing systems as described herein are also disclosed. Methods of monitoring a metabolic activity of cells, and uses thereof, are also disclosed.
Type:
Grant
Filed:
October 22, 2014
Date of Patent:
April 30, 2019
Assignee:
Ramot at Tel-Aviv University Ltd.
Inventors:
Fernando Patolsky, Le-Chang Hsiung, Vadim Krivitsky, Vladimir Naddaka
Abstract: Described herein is a porous copolymer membrane composed of poly(styrene sulfonate)-block-polyethylene-block-poly(styrenesulfonate) for use in the absorption of doxorubicin, and a chemofiltration catheter incorporating the membrane for use in transarterial chemoembolization.
Type:
Grant
Filed:
October 12, 2015
Date of Patent:
April 30, 2019
Assignee:
The Regents of the University of California
Inventors:
Xi Chelsea Chen, Jeffrey Yang, Albert Chin, Anand Patel, Steven Hetts, Nitash Balsara
Abstract: Use of H3K9me3 modulation for enhancing cognitive function and treating anxiety related disorders is presented. A composition is administered to the subject comprising a therapeutically effective amount of a SUV39H1 inhibitor comprising analogs of ETP69. The therapeutically effective amount is effective in treating cognitive dysfunction in aging and age-related disorders.
Type:
Grant
Filed:
June 3, 2016
Date of Patent:
April 30, 2019
Assignee:
Regents of the University of California
Inventors:
Carl W. Cotman, Larry E. Overman, Shikha Snigdha
Abstract: The present invention relates to a composition for preventing or treating mucositis comprising NecroX. It was found that NecroX has effects of reducing the disease mortality rate by means of radiotherapy or chemotherapy in a NecroX administration group, protecting intestinal functions, inhibiting destruction of intestinal mucous membrane, and proliferating the cells present in intestines. NecroX may be used for a pharmaceutical composition for preventing or treating mucositis, an anti-cancer adjuvant, or a food composition.
Type:
Grant
Filed:
November 3, 2015
Date of Patent:
April 30, 2019
Assignee:
The Catholic University of Korea Industry-Academic Cooperation
Inventors:
Seok Goo Cho, Keon-Il Im, Jung Yeon Lim, Nayoun Kim, Young Sun Nam, Eun Sol Lee
Abstract: Apparatus for analyzing brain MRI, is disclosed. The apparatus comprises an input for receiving a first and a second MRI scans at the beginning and end of a predetermined time interval post contrast administration; a subtraction map former for forming a subtraction map from said first and said second MRI scans by analyzing said scans to distinguish between two primary populations, a slow population, in which contrast clearance from the tissue is slower than contrast accumulation, and a fast population in which clearance is faster than accumulation; and an output to provide an indication of distribution of said two primary populations, wherein said predetermined time period is at least twenty minutes.
Type:
Grant
Filed:
October 18, 2012
Date of Patent:
April 30, 2019
Assignees:
Tel HaShomer Medical Research Infrastructure and Services Ltd., Ramot at Tel-Aviv University Ltd.
Inventors:
Leor Zach, David Guez, David Last, Dianne Daniels, Yael Mardor
Abstract: Data processing including a universal metric to quantify and estimate the similarity and dissimilarity between data sets. Data streams are perfectly annihilated by a correct realization of their anti-streams. Any deviation of the collision product from a baseline, for example flat white noise, quantifies statistical dissimilarity. The invention relates generally to data mining. More specifically, the invention relates to the analysis of data using a universal metric to quantify and estimate the similarity and dissimilarity between sets of data.
Abstract: This work provides an affordable approach for detecting environmental contaminants (e.g., arsenic in groundwater). Electro-chemical analysis of a sample is performed using a disposable three-electrode sensor that can be connected to an electrochemical analyzer (which is not disposable). The disposable sensor has a sample chamber to admit a liquid sample. The sensor includes a substrate disposed within the sample chamber that includes at least one conditioning reagent to condition the sample for electrochemical analysis. Analysis results can be displayed via a mobile device application.
Type:
Grant
Filed:
February 18, 2016
Date of Patent:
April 30, 2019
Assignee:
Santa Clara University
Inventors:
Unyoung Kim, Silvia Figueira, Shoba Krishnan
Abstract: An adapter system can include a set of adapters operably adapted to a set of microsurgical tools. Each adapter in the set of adapters can be formed for a complimentary surgical tool in the set of surgical tools. Each adapter can have a setback feature designed to orient a corresponding tool tip at a common tip distance. An adapter receptacle can include a joint or joints having a rotary motion and/or translation mechanism and a setback stop feature.
Type:
Grant
Filed:
February 11, 2016
Date of Patent:
April 30, 2019
Assignee:
University of Utah Research Foundation
Inventors:
Manikantan Nambi, Jacob J. Abbott, Paul S. Bernstein
Abstract: Systems and methods are provided for estimating power breakdowns for a set of one or more appliances inside a building by exploiting a small number of power meters and data indicative of binary power states of individual appliances of such set. In one aspect, a breakdown estimation problem is solved within a tree configuration, and utilizing a single power meter and data indicative of binary power states of a plurality of appliances. Based at least in part on such solution, an estimation quality metric is derived. In another aspect, such metric can be exploited in a methodology for optimally placing additional power meters to increase the estimation certainty for individual appliances to a desired or intended level. Estimated power breakdown and energy breakdown—individually or collectively referred to as consumption breakdown—rely on measurements and numerical simulations, and can be evaluated in exemplary electrical network utilizing binary sensors.
Abstract: The present disclosure provides nanostructures (e.g., monolayer or bilayer nanostructures) comprising porphyrins with cobalt chelated thereto such that the cobalt metal resides within monolayer or bilayer in the porphyrin macrocycle. The nanostructures can have presentation molecules with a histidine tag attached thereto, such that at least a part of the his-tag is within the monolayer or bilayer and coordinated to the cobalt metal core and the presentation molecules are exposed to the outside of the nanostructures. The nanostructures can further comprise a cargo. The nanostructures can be used to deliver the cargo to an individual.
Type:
Grant
Filed:
April 18, 2016
Date of Patent:
April 30, 2019
Assignees:
The Research Foundation for The State University of New York, PATH
Inventors:
Jonathan Lovell, Shuai Shao, Jumin Geng, Wei-Chiao Huang, Shwu-Maan Lee, Charles Richter King
Abstract: A method reuses produced water resulting from a fossil fuel extraction operation. The method includes providing the produced water as an input to an electrodialysis system. The method also includes running the electrodialysis system to produce a diluate and a concentrate. The diluate is contaminated so as to have a conductivity of no less than 0.1 Siemens/meter. The method also includes reformulating the diluate to produce fossil fuel extraction fluid. The method also includes using the produced fossil fuel extraction fluid in the fossil fuel extraction operation. An electrodialysis system includes first and second stacks. The electrodialysis system also includes first and second voltage sources, coupled to the first and second stacks, so as to apply a first voltage to the first stack lower by at least about 10% than a second voltage to the second stack.
Type:
Grant
Filed:
April 23, 2015
Date of Patent:
April 30, 2019
Assignees:
Massachusetts Institute of Technology, King Fahd University of Petroleum and Minerals
Inventors:
John H. Lienhard, Ronan Killian McGovern, Lige Sun, Adam Michael Weiner, Syed M. Zubair
Abstract: The present invention provides a new and improved oligonucleotide detection method based on the nanopore technology with a probe containing a complementary sequence to the target oligonucleotide and a terminal extension at the probe's 3? terminus, 5? terminus, or both termini. The improved nanopore sensor with the probe enables sensitive, selective, and direct detection, differentiation and quantification of target oligonucleotides such as miRNAs. The inventive detection method may also be employed as a non-invasive and cost-effective diagnostic method for cancer detection based on miRNA levels in the patient's blood sample.
Type:
Grant
Filed:
July 13, 2016
Date of Patent:
April 30, 2019
Assignee:
The Curators of the University of Missouri
Abstract: The instant invention provides methods for immortalizing cells. The invention further provides immortalized cell lines, e.g., neuronal cell lines, and methods of using these cell lines in screening assays.
Abstract: A pressure sensing device including a light source, at least one resonant structure, a cladding body, a first substrate and a second substrate is provided. The light source is configured to provide an original broadband light. The resonant structure includes a plurality of semiconductor rod structures arranged into a row at intervals along a single arranging direction, and each of the semiconductor rod structures has a lattice constant on the arranging direction. The original broadband light is transmitted between the semiconductor rod structures, and a resonant light is produced, wherein each of the semiconductor rod structures has a length perpendicular to the arranging direction and has a width parallel to the arranging direction, the length and the width are less than the wavelength of the resonant light. The cladding body completely covers the semiconductor rod structures of the at least one resonant structure.
Abstract: In certain embodiments, the present invention provides the use of microRNA (miR)-200a and/or miR-200c to inhibit ossification and bone formation. In certain embodiments, the present invention provides the use of miR-200a inhibitor to stimulate bone regeneration.
Type:
Grant
Filed:
May 1, 2017
Date of Patent:
April 30, 2019
Assignee:
University of Iowa Research Foundation
Inventors:
Liu Hong, Brad Amendt, Thad Sharp, Aliasger Salem