Abstract: Energy-filtered cold electron devices use electron energy filtering through discrete energy levels of quantum wells or quantum dots that are formed through band bending of tunneling barrier conduction band. These devices can obtain low effective electron temperatures of less than or equal to 45K at room temperature, steep electrical current turn-on/turn-off capabilities with a steepness of less than or equal to 10 mV/decade at room temperature, subthreshold swings of less than or equal to 10 mV/decade at room temperature, and/or supply voltages of less than or equal to 0.1 V.
Type:
Grant
Filed:
June 27, 2018
Date of Patent:
April 30, 2019
Assignee:
Board of Regents, The University of Texas System
Inventors:
Seong Jin Koh, Pradeep Bhadrachalam, Liang-Chieh Ma
Abstract: A target tissue can be treated with a radioisotope. Some methods for treating a target tissue with a radioisotope include determining a distance between a target tissue and a surface of a matrix material to be positioned adjacent the target tissue and, based on the determined distance, determining an activity to be mixed with the matrix material to obtain a desired activity concentration. Some methods further include mixing the radioisotope with the matrix material. In some embodiments, the matrix material comprises bone cement, and the target tissue is a tumor in a bone. The radioisotope may be a beta-emitting radioisotope mixed in the cement at a concentration to form a radioactive cement.
Type:
Grant
Filed:
March 20, 2017
Date of Patent:
April 30, 2019
Assignee:
The Regents of the University of California
Inventors:
Joyce H. Keyak, Tadashi Kaneko, Harry B. Skinner, Varun Sehgal
Abstract: Provided herein are methods for detecting and identifying strains of mycobacteria, and compositions and kits for performing such methods. In particular, nucleic acid amplification and fluorescence detection methods are provided for the detection and differentiation of mycobacteria based on, for example, pathogenicity, species, and antibiotic resistance or sensitivity. Compositions and methods are provided herein to identify and differentiate mycobacteria in mixtures of different mycobacteria and mycobacteria and non-mycobacteria.
Abstract: Provided are 1) a hollow fiber cryopreservation instrument having a long support on which a hollow fiber is placed, wherein the support is formed of a low-temperature-resistant material, and 2) a cell cryopreservation method having a process of placing a hollow fiber on the support of the hollow fiber cryopreservation instrument, and a process of cryopreserving cells in a state in which the hollow fiber is placed on the support.
Abstract: A parameter determination device includes: a spectral envelope estimating portion performing estimation of a spectral envelope using a parameter ?0 specified in a predetermined method, regarding the ?0-th power of absolute values of a frequency domain sample sequence corresponding to a time-series signal as a power spectrum on the assumption that the parameter ?0 and a parameter ? are positive numbers; a whitened spectral sequence generating portion obtaining a whitened spectral sequence which is a sequence obtained by dividing the frequency domain sample sequence by the spectral envelope; and a parameter acquiring portion determining such a parameter ? that generalized Gaussian distribution with the parameter ? as a shape parameter approximates a histogram of the whitened spectral sequence.
Type:
Grant
Filed:
January 27, 2016
Date of Patent:
April 30, 2019
Assignees:
NIPPON TELEGRAPH AND TELEPHONE CORPORATION, The University of Tokyo
Abstract: A noninvasive arterial condition detecting system includes a processing device and an electronic stethoscope configured for auscultating carotid artery to receive sound signals. The processing device is connected to the electronic stethoscope. The processing device records the sound signals, preprocesses the sound signal to reduce noise, measures a trough-peak distance and a trough-peak time, and generates an estimate result of arterial conditions according to the trough-peak distance and the trough-peak time. The trough-peak distance and the trough-peak time are related to the health of the carotid artery walls.
Abstract: A system for testing thermal response time of an uncooled infrared focal plane detector array and a method therefor is provided. The system comprises: a blackbody, a chopper, a detector unit under test and a testing system. The method comprises: emitting radiation by the blackbody, chopping by the chopper, then radiating the radiation to the uncooled infrared focal plane detector array under test; generating different responses on the radiation at different chopping frequencies by the uncooled infrared focal plane detector array under test; collecting different response values of the uncooled infrared focal plane detector array under test at different chopping frequencies; obtaining response amplitude at a corresponding frequency in a frequency domain by FFT; fitting according to a formula Rv ? ( f ) = Rv ? ( 0 ) 1 + ( 2 ? ? ? ? f ? ? ? ) 2 to obtain the thermal response time.
Type:
Grant
Filed:
May 2, 2018
Date of Patent:
April 30, 2019
Assignee:
University of Electronic Science and Technology of China
Abstract: A process for making an iron oxide impregnated carbon nanotube membrane. In this template-free and binder-free process, iron oxide nanoparticles are homogeneously dispersed onto the surface of carbon nanotubes by wet impregnation. The amount of iron oxide nanoparticles loaded on the carbon nanotubes range from 0.25-80% by weight per total weight of the doped carbon nanotubes. The iron oxide doped carbon nanotubes are then pressed to form a carbon nanotube disc which is then sintered at high temperatures to form a mixed matrix membrane of iron oxide nanoparticles homogeneously dispersed across a carbon nanotube matrix. Methods of characterizing porosity, hydrophilicity and fouling potential of the carbon nanotube membrane are also described.
Type:
Grant
Filed:
July 17, 2017
Date of Patent:
April 30, 2019
Assignee:
King Fahd University of Petroleum and Minerals
Inventors:
Muataz Ali Atieh, Ihsanullah, Tahar Laoui
Abstract: Tap guide assembly devices, systems, and methods are disclosed herein. A tap guide assembly can have a body assembly, a tension pin assembly, a tension spring, and a setscrew. The body assembly can have an elongate body and a drill bushing. The drill bushing can have a diameter that is less than the diameter of the elongate body and can be positioned within a portion of the elongate body. The tension pin assembly can have a pin and a collar and can be configured to be received within the body assembly. The tension spring can be positioned proximate to the collar. The setscrew can be securely positioned proximate to the tension spring and within the second opening of the elongate body.
Type:
Grant
Filed:
June 20, 2017
Date of Patent:
April 30, 2019
Assignee:
University of Alaska Anchorage
Inventors:
Philip W. Boysen, Joshua D. Gunderson, Anthony J. Paris
Abstract: A middle ear implant may include a first interface portion configured to interface with a first structure of a middle ear of a patient, a second interface portion configured to interface with a second structure of the middle ear of the patient, a shaft configured to connect the first interface portion and the second interface portion, and a sensor disposed at one end of the shaft, between the shaft and one of the first interface portion or the second interface portion. The sensor may be configured to provide a DC signal output indicative of static pressure on the sensor based on placement of the sensor between the first and second structures. The sensor may also be configured to provide an AC signal output indicative of a frequency response of the implant in response to the sensor being coupled to an output device.
Type:
Grant
Filed:
July 10, 2017
Date of Patent:
April 30, 2019
Assignee:
The Johns Hopkins University
Inventors:
Dawnielle Farrar-Gaines, George L. Coles, Jr., David A. Kitchin, Howard W. Francis, Ioan Lina
Abstract: The present invention relates to compositions and methods for treating diseases associated with dyslipidemia, including hypercholesterolemia, hypertriglyceridemia, steatohepatitis, atherosclerosis, obesity, hyperglycemia, metabolic syndrome, and related aspects of and conditions associated with metabolic syndrome. The compositions and methods disclosed herein are useful for regulating the lipid balance (lipid homeostasis) in a subject. Compositions and methods including a Nuclear Transport Modifier may be administered to a subject to modulate the transport of transcription factors, mediated by nuclear import adaptors, into the nucleus of a cell resulting in a decrease in cholesterol and triglyceride levels in the blood and liver, a decrease in atherosclerotic lesion size, a decrease in body weight and in hyperglycemia, a reduction of fatty liver inflammation, and an improvement in liver function.
Type:
Grant
Filed:
November 6, 2017
Date of Patent:
April 30, 2019
Assignee:
Vanderbilt University
Inventors:
Jack J. Hawiger, Ruth Ann Veach, Jozef Zienkiewicz, Yan Liu, Robert D. Collins, Amy S. Major
Abstract: An optical fiber system including an optical fiber and an optical grating is provided. The optical fiber is configured to support M mode groups, where differences in effective refractive index between adjacent mode groups are substantially equal. The optical grating is optically coupled to the optical fiber, and has a period inversely proportional to the difference in effective refractive index between adjacent mode groups. The optical grating is configured to couple all adjacent mode groups in the optical fiber.
Type:
Grant
Filed:
February 15, 2018
Date of Patent:
April 30, 2019
Assignees:
Futurewei Technologies, Inc., University of Central Florida Research Foundation, Inc.
Inventors:
Guifang Li, Zhihong Li, Demetrios Christodoulides, Huiyuang Liu, He Wen, Mohammadamin Eftekhar, Bin Huang
Abstract: Selecting and ranking valid variants in search and recommendation systems selects and ranks variants with accuracy and speed. Criteria for evaluating the relevance of a variant to the search request are generated. A set of procedures for the selection and ranking of variants and a sequence for performing said procedures for the selection of variants evaluated as the most valid are established. An evaluation of each variant is based on relevance to search request criteria. The variants are then ranked by assigning a rank to each variant based on the condition of correspondence to the greatest number of criteria in decreasing order. Then the variants are selected and ranked in at least two stages using the superposition method, and the variants are selected, ranked and excluded until all of the established selection procedures have been used and the selected group of variants is evaluated as being the most valid.
Type:
Grant
Filed:
September 17, 2015
Date of Patent:
April 30, 2019
Assignee:
National Research University Higher School of Economics (HSE)
Inventors:
Fuad T. Aleskerov, Evgeny O. Mitichkin, Vyacheslav V. Chistyakov, Sergey V. Shvydun, Viacheslav I. Iakuba
Abstract: According to one aspect, the subject matter described herein includes a near-eye optical see-through display. The display includes a backlight layer including a plurality of point light sources. The display further includes a spatial light modulator (SLM) layer for modulating light from the point light sources. The spatial light modulator is located in the optical path between the point light sources and a user's eye. The spatial light modulator layer includes pixels that are controllable to modulate light from the point light sources such that the light that impacts the user's eye has a desired intensity and color to display a synthetic image. At least a portion of the backlight layer and the spatial light modulator layer are optically transparent to allow a user to view a real scene through the spatial light modulator layer and the backlight layer such that the synthetic image appears to be overlaid on a view of the real scene.
Type:
Grant
Filed:
December 19, 2014
Date of Patent:
April 30, 2019
Assignee:
The University of North Carolina at Chapel Hill
Abstract: A vehicle position estimating apparatus may include a position estimation device that maps objects recognized by a sensor of the vehicle and located around of the vehicle to a parking lot map and estimates a position of the vehicle based on movement information related to the vehicle, a weight setting device that predicts a mapping accuracy of the objects using a detected result of a landmark mapped to the parking lot map by the sensor and gives a weight to each particle corresponding to an interest point of each object based on the predicted mapping accuracy of the objects, and a position correction device that corrects the estimated position of the vehicle using the each weighted particle.
Type:
Grant
Filed:
July 17, 2017
Date of Patent:
April 30, 2019
Assignees:
Hyundai Motor Company, Kia Motors Corporation, Korea University Research and Business Foundation
Inventors:
Min Wook Seo, Dae Hie Hong, Yun Sik Kim
Abstract: The present invention relates to methods for treating and/or preventing tumors and/or promoting apoptosis in a neoplastic cell comprising contacting the neoplastic cell with an cell-penetrating dominant-negative ATF5 (“CP-d/n-ATF5”), wherein the CP-d/n-ATF5 is capable of inhibiting ATF5 function and/or activity.
Type:
Grant
Filed:
December 22, 2017
Date of Patent:
April 30, 2019
Assignees:
The Regents of the University of California, The Trustees of Columbia University in the City of New York
Abstract: Self-interference cancellers are provided. The self-interference cancellers can include multiple second-order, N-path Gm-C filters. Each filter can be configured to cancel self-interference on a channel of a desired bandwidth. Each filter can be independently controlled using a variable transmitter resistance, a variable receiver resistance, a variable baseband capacitance, a variable transconductance, and a variable time shift between local oscillators that control switches in the filter. By controlling these variables, magnitude, phase, slope of magnitude, and slope of phase of the cancellers frequency responses can be controlled for self-interference cancellation. A calibration process is also provided for configuring the canceller.
Type:
Grant
Filed:
October 1, 2015
Date of Patent:
April 30, 2019
Assignee:
The Trustees of Columbia University in the City of New York
Abstract: A semiconductor device includes a semiconductor substrate comprising a group III element and a group V element, and a gate structure on the semiconductor substrate. The semiconductor substrate includes a first region which contacts a bottom surface of the gate structure and a second region which is disposed under the first region. The concentration of the group III element in the first region is lower than that of the group V element in the first region, and the concentration of the group III element in the second region is substantially equal to that of the group V element in the second region.
Type:
Grant
Filed:
October 27, 2016
Date of Patent:
April 30, 2019
Assignees:
Samsung Electronics Co., Ltd., Seoul National University R&DB Foundation
Inventors:
Ha-Jin Lim, Hyeong-Joon Kim, Nae-In Lee