Abstract: A method for treating a substrate is provided. The method includes supplying a first treating liquid to a treating target surface of the substrate while the substrate is rotating, and subsequently, supplying a second treating liquid having a surface tension lower than a surface tension of the first treating liquid to the substrate while an evaporation inhibiting agent in a vapor state is present around the first treating liquid supplied to the substrate, such that the first treating liquid on the substrate is substituted with the second treating liquid. Thus, a vapor atmosphere may be formed around a cleaning liquid applied to the substrate. Thus, a liquid-film destroying phenomenon may be prevented in a procedure in which the cleaning liquid is replaced with an organic solvent.
Type:
Grant
Filed:
May 14, 2020
Date of Patent:
January 25, 2022
Assignees:
SEMES CO., LTD., SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION
Inventors:
Seungtae Yang, Buyoung Jung, Gui Su Park, Jae Hong Lee, Ho-Young Kim, Yunsuk Jeung
Abstract: The present disclosure provides compositions and methods for treatment of a kidney disease with chemokine protein stromal cell-derived factor 1 (SDF-1), such as methods of treating a subject afflicted with or at risk of developing a kidney disease, comprising administering SDF-1 to a kidney of the subject in a treatment-effective amount.
Abstract: Disclosed is a method of producing an antimicrobial peptide wherein an antimicrobial peptide gene is fused with a green fluorescent protein gene expressed insolubly in E. coli, followed by introduction into E. coli, expression, and removal of the green fluorescent protein to yield the antimicrobial peptide. This method is capable of producing the antimicrobial peptide with high yield in a simple and economical manner and is thus effective at providing native antibiotics that can replace conventional antibiotics in pharmaceutical and feed industries, requiring the development of antibiotics having a new mechanism of action that can eradicate resistant strains due to the proliferation of multiple-drug-resistant microorganisms. Furthermore, the use of an amino acid cleavage process through acid treatment, instead of using conventional cyanogen bromide, is cost-effective for the purification of a target protein from an insoluble protein, can decrease the risk of processing, and enables rapid processing.
Type:
Grant
Filed:
February 26, 2016
Date of Patent:
January 25, 2022
Assignee:
Konkuk University Industrial Cooperation Corp
Abstract: An optical system includes at least one laser source configured to generate first light having a first spectrum comprising a plurality of first peaks, a waveform generator configured to produce a noise waveform, and an electro-optic phase modulator in optical communication with the at least one laser source and in electrical communication with the waveform generator. The electro-optic phase modulator is configured to receive the first light, to receive the noise waveform, and to respond to the noise waveform by modulating the first light to produce second light having a second spectrum comprising a plurality of second peaks. The peak wavelengths of the second peaks are equal to the peak wavelengths of the first peaks and the linewidths of the second peaks are broader than the linewidths of the corresponding first peaks.
Type:
Grant
Filed:
October 15, 2020
Date of Patent:
January 25, 2022
Assignee:
The Board of Trustees of the Leland Stanford Junior University
Inventors:
Michel J. F. Digonnet, Jonathan M. Wheeler
Abstract: The present invention provides a method for manufacturing a curved thin-walled intermetallic compound component by winding a mandrel with metal foil strips, which comprises the following steps: designing a prefabricated blank; preparing a support mandrel; determining thicknesses and layer numbers of foil strips; determining widths of the foil strips; establishing a laying process; pretreating surfaces of the foil strips; laying A foil and B foil; carrying out bulge forming on the prefabricated blank; carrying out diffusion reaction and densification treatment on a bulged component; and carrying out subsequent treatment of a thin-walled component. The present invention can solve the problems that impurities generated in the separation process of a support mould and a laminated foil prefabricated blank influence the final performance of a part, and a single homogeneous intermetallic compound component in thickness direction has poor plasticity and toughness at room temperature.
Abstract: Systems and methods of encrypted communication between a server and client devices using keyless encryption schemes are disclosed. Client devices with arrays of physical-unclonable-function devices respond to challenges from a server. Characteristics of the arrays are stored by the server during a secure enrollment process. Subsequently, the server issues challenges to the clients. The clients derive a ciphertext according to a variable cipher scheme determined using responses to the challenges issued by the server using characteristics of portions of the arrays specified by the challenges. The server and clients may independently determine encryption and decryption procedures using characteristics of the arrays.
Type:
Grant
Filed:
December 23, 2019
Date of Patent:
January 25, 2022
Assignee:
Arizona Board of Regents on Behalf of Northern Arizona University
Abstract: Method and system for controlling a vehicle that includes using velocity vectors of obstacles in the vehicle's environment to determining boundaries of the one or more obstacles and thereby generate a velocity space that may include velocity vectors for the vehicle and which are represented as collision cones. The using an identified velocity vector in combination with the velocity vectors of the one or more obstacles to produce a maximum motion in of the vehicle towards a target location while avoiding all determined collision cones.
Type:
Grant
Filed:
July 25, 2018
Date of Patent:
January 25, 2022
Assignee:
King Fahd University of Petroleum and Minerals
Inventors:
Haseeb Tahir, Uthman Baroudi, N. Mujahid Syed
Abstract: Provided is a method of producing a silicon compound material, including the steps of: storing a silicon carbide preform in a reaction furnace; supplying a raw material gas containing methyltrichlorosilane to the reaction furnace to infiltrate the preform with silicon carbide; and controlling and reducing a temperature of a gas discharged from the reaction furnace at a predetermined rate to subject the gas to continuous thermal history, to thereby decrease generation of a liquid or solid by-product derived from the gas.
Type:
Grant
Filed:
January 4, 2019
Date of Patent:
January 25, 2022
Assignees:
IHI Corporation, The University of Tokyo
Abstract: A novel organic sulfur compound, a method for preparing the same, and a pharmaceutical composition for preventing or treating cancer or inflammatory diseases, containing the same as an active ingredient are provided. The novel organic sulfur compound is capable of excellently inhibiting histone deacetylated (HDAC) enzymes in a concentration of nanomolar or micromolar units and has been found to have an excellent effect against inflammatory diseases, and has been found to be capable of inhibiting the proliferation of cancer.
Type:
Grant
Filed:
July 17, 2017
Date of Patent:
January 25, 2022
Assignee:
Sookmyung Womens University Industry-Academic Cooperation Foundation
Abstract: A method for directly writing metal traces on a wide range of substrate materials is disclosed. The method includes writing a pattern of particle-free metal-salt-based ink on the substrate followed by a plasma-based treatment to remove the non-metallic components of the ink and decompose its metal salt into pure metal. The ink is based on a multi-part solvent whose components differ in at least one of evaporation rate, surface tension, and viscosity, which improves the manner in which the ink is converted into its metal constituent via the plasma treatment. In some embodiments, a microplasma is used for post-treatment of the deposited ink, where the plasma properties are controlled to provide different material properties, such as porosity and effective resistivity, in different regions of the metal pattern.
Type:
Grant
Filed:
April 13, 2018
Date of Patent:
January 25, 2022
Assignees:
Case Western Reserve University, THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF VETERANS AFFAIRS
Inventors:
Christopher J. Miller, Souvik Ghosh, Yongkun Sui, R. Mohan Sankaran, Christian A. Zorman
Abstract: Disclosed herein is a composite comprising an elastomer with an embedded network of liquid metal inclusions. The composite retains similar flexibility to that of an elastomer but exhibits electrical and thermal properties that differ from the properties of a homogeneous elastomer. The composite has applications for wearable devices and other soft matter electronics, among others.
Type:
Grant
Filed:
April 13, 2020
Date of Patent:
January 25, 2022
Assignee:
CARNEGIE MELLON UNIVERSITY, a Pennsylvania Non-Profit
Corporation
Inventors:
Carmel Majidi, Andrew Fassler, Michael Bartlett, Navid Kazem, Matthew J. Powell-Palm, Jonathan A. Malen
Abstract: A semiconductor device includes a III-nitride buffer layer and a III-nitride barrier layer. A boron nitride alloy interlayer interposed between the III-nitride buffer layer and the III-nitride barrier layer. A portion of the III-nitride buffer layer includes a two-dimensional electron gas (2DEG) channel that is on a side of the III-nitride buffer layer adjacent to the boron nitride alloy interlayer.
Type:
Grant
Filed:
October 15, 2018
Date of Patent:
January 25, 2022
Assignee:
KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY
Abstract: An operation method of a base station in a time division duplex communication system includes: a step for setting a time period in which a terminal can transmit an uplink in a downlink period; a step for generating a sparse vector signal including information about the time period; and a step for transmitting the sparse vector signal to the terminal. In addition, an operation method of the terminal in the time division duplex communication system includes: a step for receiving a part of a sparse vector signal from the base station; a step for recovering the received sparse vector signal by compressed sensing; and a step for transmitting uplink data in a time period instructed in a downlink period based on the basis of the recovered signal.
Type:
Grant
Filed:
November 22, 2017
Date of Patent:
January 25, 2022
Assignee:
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION
Abstract: In a networking system including a plurality of nodes connected with each other by a communication network, each node includes an abnormality discrimination unit configured, when a cumulative consumption current at the time of processing the data received from other node is out of a range (of current values estimated in advance based on an event at the other node, to discriminate the other node as an abnormal. By the networking system, the abnormality of the nodes on the network may be detected with a simple configuration.
Abstract: A DC-DC voltage converter includes an input circuit, a parallel linked leg (PLL), an output circuit and a controller. The PLL includes an active leg switch, a leg inductor, a leg capacitor and a leg diode. The controller is configured to i) turn on the active input switch and the active leg switches while maintaining the active output switch at a turn off state for the first duty cycle period ii) turn off the active input switch and the active leg switches, and turn on the active output switch for a second duty cycle period following the first duty cycle period, and iii) turn off the active output switch while maintaining also turn off states of the active input switch and the active leg switches for a remaining period following the second duty cycle period. A method of controlling the DC-DC converter includes steps of i) to iii).
Abstract: A rotationally compliant bearing roller assembly having a roller, at least one bearing member operably coupled to a base configured to support rotational movement about a rotational axis; and a rotary compliant joint interconnecting the at least one bearing member to the roller. The rotary compliant joint having a first compliance in a rotational direction about the rotational axis to permit movement of the roller in the rotational direction relative to the at least one bearing member, such that the first compliance being greater than a friction induced compliance of the at least one bearing member in the rotational direction. The compliant joint having a second compliance in a direction orthogonal to the rotational direction, such that the second compliance being less than the first compliance.
Type:
Grant
Filed:
October 5, 2020
Date of Patent:
January 25, 2022
Assignees:
THE REGENTS OF THE UNIVERSITY OF MICHIGAN, Korea Institute of Machinery & Materials
Inventors:
Chinedum E. Okwudire, Xin Dong, Dongwoo Kang
Abstract: Amine substituted morpholino oligonucleotides, other than the classical N,N-dimethylamino PMO analogue, and methods of efficiently synthesizing these oligonucleotides with high yield are provided. Morpholino oligonucleotides having thiophosphoramidate, phosphoramidate, and alkyl phosphoramidate linkers. Chimeras containing unmodified DNA/RNA and other analogs of DNA/RNA can be prepared. These oligonucleotides form duplexes with complementary DNA or RNA that are more stable than natural DNA or DNA/RNA complexes, are active with RNAse H1, and may be transfected into cells using standard lipid reagents. These analogues are therefore useful for numerous applications.
Type:
Grant
Filed:
March 20, 2019
Date of Patent:
January 25, 2022
Assignee:
THE REGENTS OF THE UNIVERSITY OF COLORADO
Abstract: Provided herein are recombinant peptides useful for inhibiting the function of autophagy-related 8 (Atg8) proteins. The recombinant peptides can be used in the preparation of imaging agents for monitoring autophagy in a cell or subject and treating autophagy related diseases, such as cancer.
Type:
Grant
Filed:
November 5, 2018
Date of Patent:
January 25, 2022
Assignee:
The Hong Kong University of Science and Technology
Inventors:
Mingjie Zhang, Jianchao Li, Ruichi Zhu, Chao Wang
Abstract: The camel-milk products with plant-based protein additives include camel milk in the form of plant-based milk, plant-based milk powder and/or derivatives thereof and have enhanced gel strength. The plant-based protein additives may be derived from soybeans; oats; almonds; lupin chickpeas or navy beans. The camel-milk products include fermented and non-fermented camel-milk products, such as: set and stir yogurt; all cheese varieties; cultured camel milks; and custard-based products. The camel-milk products are prepared by mixing camel milk with plant-based protein additives to form a mixture and coagulating the mixture by acid or enzyme treatment.
Abstract: Compositions and methods for making and using proliposomal and liposomal formulations of chemotherapeutic agents are disclosed. The proliposomal and liposomal formulations of chemotherapeutics, as well as medicaments and dosage forms that include such formulations, can be used with treatment regimens for bladder cancer and urothelial cancer. Hence, the formulations, medicaments, and dosage forms of the invention are suitable to treat bladder cancers by intravesical administration and to treat urothelial cancers. The formulations according to the invention include (a) a taxane (e.g., paclitaxel, docetaxel) or cisplatin, (b) a first phospholipid, dipalmitoyl phosphatidylcholine (DMPC), and (c) a second phospholipid, dimyrsityl phosphatidyl glycerol sodium (DMPG). The proliposomal formulations form liposomes upon contact with an aqueous vehicle.
Type:
Grant
Filed:
January 9, 2017
Date of Patent:
January 25, 2022
Assignees:
WESTERN UNIVERSITY OF HEALTH SCIENCES, TESORX PHARMA, LLC
Inventors:
Guru V. Betageri, Natarajan Venkatesan, Michael G. Oefelein, Ramachandran Thirucote, Nitin Kumar Swarnakar, Teresa Hong