Abstract: A computerized method of providing automatic anatomy recognition (AAR) includes gathering image data from patient image sets, formulating precise definitions of each body region and organ and delineating them following the definitions, building hierarchical fuzzy anatomy models of organs for each body region, recognizing and locating organs in given images by employing the hierarchical models, and delineating the organs following the hierarchy. The method may be applied, for example, to body regions including the thorax, abdomen and neck regions to identify organs.
Type:
Grant
Filed:
May 14, 2015
Date of Patent:
January 25, 2022
Assignee:
The Trustees of the University of Pennsylvania
Inventors:
Jayaram K. Udupa, Dewey Odhner, Drew A. Torigian, Yubing Tong
Abstract: The camel-milk products with plant-based protein additives include camel milk in the form of plant-based milk, plant-based milk powder and/or derivatives thereof and have enhanced gel strength. The plant-based protein additives may be derived from soybeans; oats; almonds; lupin chickpeas or navy beans. The camel-milk products include fermented and non-fermented camel-milk products, such as: set and stir yogurt; all cheese varieties; cultured camel milks; and custard-based products. The camel-milk products are prepared by mixing camel milk with plant-based protein additives to form a mixture and coagulating the mixture by acid or enzyme treatment.
Abstract: Methods for treating or prophylaxis of a cryptosporidium infection using compositions comprising a structure disclosed herein. Also provided are pharmaceutical compositions and kits for alleviating the symptoms of, for treating, or for preventing the occurrence of cryptosporidium infection. The kits comprise one or more compounds having a structure disclosed herein, such as in an oral composition, and instructions for use, storage, and the like.
Type:
Grant
Filed:
July 29, 2019
Date of Patent:
January 25, 2022
Assignee:
University of Vermont and State Agricultural College
Inventors:
Christopher D. Huston, Kovi Bessoff, Rajiv Satish Jumani
Abstract: Novel compounds and compositions containing (R)-3-hydroxybutyrate derivatives are disclosed. The compounds and compositions can be used as nutritional supplements to increase physical performance and as therapeutics to ameliorate symptoms of medical conditions, particularly neurological conditions, such as Alzheimer's and similar conditions. Novel methods for making R-3-hydroxybutyrate derivatives also are disclosed. Exemplary methods employ a supercritical solvent, such as supercritical carbon dioxide, and employ a lipase catalyzed esterification or transesterification reaction to produce the (R)-3-hydroxybutyrate derivatives.
Type:
Grant
Filed:
March 7, 2018
Date of Patent:
January 25, 2022
Assignees:
Oxford University Innovation Limited, U.S. Dept. Of Health and Human Services, (DHHS), U.S. Government
Inventors:
Richard Lewis Veech, Michael Todd King, Kieran Clarke
Abstract: An aspect of the present disclosure is to provide a device or needle placement system including a needle having a proximal end and a distal end, and an ultrasound transducer element attached to the distal end of the needle. The system also includes a needle constraining assembly configured to receive and constrain the needle to only rotational degrees of freedom within a range of angular motion. The system further includes a needle sensor system incorporated into the constraining assembly to sense an angular orientation of the needle with the range of angular motion. The system also includes an ultrasound data processor configured to communicate with the transducer element to receive ultrasound detection signals and communicate with the needle sensor system to receive needle angular orientation signals. Based on the ultrasound detection and the needle angular orientation signals, the ultrasound data processor can calculate synthetic aperture ultrasound images.
Type:
Grant
Filed:
May 2, 2017
Date of Patent:
January 25, 2022
Assignee:
The Johns Hopkins University
Inventors:
Nisu Patel, Ernest Scalabrin, Karun Kannan, Kush Gupta, Larissa Chan, Mateo Paredes, Melissa Lin, Shayan Roychoudhury, Suraj Shah, Abhay Moghekar, Emad M. Boctor, Nicholas J. Durr, Younsu Kim, Haichong K. Zhang
Abstract: Disclosed are examples for printing a one-dimensional (1D) nanomaterial for use in stretchable electronic devices. An ink comprising a nanomaterial solution is dispersed from a pneumatic dispensing system of a printing device. The 1D nanomaterial is printed in a predefined pattern on an underlying substrate positioned on a ground electrode. A voltage is applied between the printing nozzle and the ground electrode to cause the ink to form into a cone during the printing. The substrate can be modified to increase the wettability of the substrate to enhance adhesion of the ink to the substrate.
Type:
Grant
Filed:
February 18, 2020
Date of Patent:
January 25, 2022
Assignee:
North Carolina State University
Inventors:
Yong Zhu, Jingyan Dong, Zheng Cui, Yiwei Han
Abstract: Inductor designs and methods are provided. An inductor can include a first core and a second core. The first core can be larger than the second core and the second core can be seated within the inner diameter of the first core. A first and a second wire can be provided that each wrap around the first core and the second core. The first core can have less windings than the second core.
Type:
Grant
Filed:
March 1, 2018
Date of Patent:
January 25, 2022
Assignee:
University of Florida Research Foundation, Incorporated
Abstract: Organic devices comprising an organic semiconducting acceptor motif coupled to a donor motif. Examples include IOTIC-2F, ITOTIC-2F, COTIC-4F, and SiOTIC-4F as acceptor materials. The acceptor materials have narrow bandgap (1.1 eV-1.3 eV), strong near-IR absorption and high solar cell EQE in near infrared (IR) region. The acceptor materials may also be used as the absorbing/light sensitive region in an IR photodetector.
Type:
Grant
Filed:
November 2, 2018
Date of Patent:
January 25, 2022
Assignee:
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Inventors:
Martin Seifrid, Guillermo C. Bazan, Jaewon Lee, Thuc-Quyen Nguyen, Benjamin R. Luginbuhl
Abstract: The present invention provides vaccines for treating or preventing a herpes simplex virus infection and methods of using and making the vaccine. Further provided are recombinant herpes simplex virus genomes, recombinant viruses, and immunogenic compositions.
Type:
Grant
Filed:
February 7, 2020
Date of Patent:
January 25, 2022
Assignee:
Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
Abstract: A method of treating a fungal infection in a subject includes topically administering to the subject a therapeutically effective amount of a fungal iron acquisition inhibitor to treat fungal infection in the subject.
Abstract: An electrostatic linear ion trap has first and second axially aligned ion mirrors separated by a charge detection cylinder axially aligned with each ion mirror. Electric fields are selectively established within the first and second ion mirrors in a manner which causes an ion in the trap to oscillate back and forth through the charge detection cylinder between the first and second ion mirrors with a duty cycle, corresponding to a ratio of time spent by the ion passing through the charge detection cylinder and total time spent traversing a combination of the first and second ion mirrors and the charge detection cylinder during one complete oscillation cycle, of approximately 50%.
Abstract: Embodiments of the disclosure are drawn to a low-voltage temperature sensor. The temperature sensor may include a waveform generator, a complementary-to-absolute-temperature (CTAT) voltage generator, a voltage reference, two comparators, and digital logic. A waveform of the waveform generator may be compared to both the CTAT voltage and the voltage reference. The output of the comparison of the CTAT and the waveform may be a pulse-width modulated signal that is temperature-dependent. The output of the comparison of the voltage reference and the waveform may be a signal with constant pulse width. The digital logic may receive the pulsed signals and take a ratio of the two signals to determine a temperature.
Abstract: It is provided novel anti-galactofuranose antibodies and their use for diagnosis of and/or treating aspergillosis, and for the design of chimeric antigen receptor T-cells, wherein single chain variable fragment of the antibodies, such as a heavy chain variable region or a light chain variable region, is fused via a spacer and a transmembrane domain to a signaling endodomain to generate an expression cassette that will be integrated into a T cell.
Type:
Grant
Filed:
March 23, 2020
Date of Patent:
January 25, 2022
Assignees:
THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY, THE GOVERNORS OF THE UNIVERSITY OF ALBERTA
Inventors:
Donald Christopher Sheppard, Benjamin Alfred William Rufus Ralph, Todd Lambert Lowary, Susmita Sarkar, Amira Ibrahim Aly Mohamed Khalil
Abstract: Humanized antibody to a pathologically mislocated form of N-cadherin detects and eliminates cells that express the protein extracellularly. These cells are found in fibrotic conditions within heart, lung, and liver, as well as kidney, skin, and other organs effected by fibrosis. The antibody does not affect cells with normal, subcellular location of the protein.
Type:
Grant
Filed:
March 9, 2020
Date of Patent:
January 25, 2022
Assignee:
Duke University
Inventors:
Paul Ferrell, Salvatore Pizzo, Robin Bachelder
Abstract: The image decoding method according to the present invention comprises the steps of: determining the availability of a block adjacent to a current block; configuring a merge candidate list for the current block on the basis of the result of the determined availability; and performing motion compensation for the current block on the basis of the merge candidate list, wherein the step of determining availability comprises the steps of inducing block availability information on the adjacent block and inducing the availability of motion information on the adjacent block, and the step of determining the availability of the adjacent block is such that when there is more than one adjacent block, the availability of adjacent blocks can be determined in accordance with a predetermined order restriction.
Type:
Grant
Filed:
October 24, 2019
Date of Patent:
January 25, 2022
Assignees:
Electronics and Telecommunications Research Institute, University-Industry Cooperation Group of Kyung Hee University
Inventors:
Hui Yong Kim, Sung Chang Lim, Jin Soo Choi, Jin woong Kim, Gwang Hoon Park, Kyung Yong Kim
Abstract: A traffic regulation system and method which combines energy harvesting from the movement of a plurality of vehicles on a roadway with wireless directional power beam transmission using the harvested energy to encourage compliance with traffic regulations. Electric power is generated from the movement of the moving vehicles by using a wind turbine to harvest wind energy from the movement of vehicles or by piezoelectric plates which harvest compression energy from the weight of the vehicle tires on the road surface. The electric power is transmitted to electric or hybrid vehicles which comply with the traffic regulations. The traffic regulations are one of driving at a posted speed and driving at a safe following distance. A control system adjusts the traffic regulation based on measurements received from a plurality of detectors.
Abstract: An instrument for fixedly transplanting a living body embryo into a uterus has an instrument, for transplanting the living body embryo into the uterus, which is to be inserted into a uterus and a magnetic embryo accommodation container holding instrument (transferred embryo fixing instrument) to be attached to the living body. The instrument for transplanting the living body embryo into the uterus has an embryo accommodation container having an embryo accommodation part having an embryo insertion portion communicating with outside and a magnetic material and a shaft-shaped container transfer tool for separably holding the embryo accommodation container at its distal end portion. The magnetic container holding instrument has an attaching part to be attached to an epidermis of the living body and a magnet capable of attracting the magnetic material of the embryo accommodation container thereto.
Type:
Grant
Filed:
July 15, 2019
Date of Patent:
January 25, 2022
Assignees:
THE UNIVERSITY OF TOKYO, ST. MARIANNA UNIVERSITY SCHOOL OF MEDICINE, KITAZATO CORPORATION
Abstract: The present invention provides, in some aspects, bilayered and trilayered pharmaceutical implant compositions for the unidirectional delivery of anti-cancer compounds to the brain over a period of time (e.g., several weeks, 1, 2, 3, 4, 5, 6, 7 days, or 1, 2, 3, weeks, or any range derivable therein) following the removal of glioblastoma multiforme or other malignant tumors in the brain.
Type:
Grant
Filed:
October 4, 2019
Date of Patent:
January 25, 2022
Assignee:
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
Inventors:
Michael J. McGinity, Feng Zhang, John R. Floyd, James W. McGinity