Abstract: Methods, systems, and computer readable media for using variable metadata tags. A method occurs at a metadata processing system for enforcing security policies in a processor architecture. The method comprises: receiving, at the metadata processing system, a tag associated with a word in memory, wherein the tag indicates a memory location containing metadata associated with the word and wherein the tag length is at least in part determined using tag usage frequency; obtaining the metadata from the memory location, and determining, using the metadata, whether the word or a related instruction violates a security policy.

Abstract: Provided are methods involving combination therapy comprising administering to an individual in need thereof an antibody that preferentially depletes human B10 cells and an immune checkpoint inhibitor. Antibodies for use in the methods are also provided.

Abstract: Aspects of the subject disclosure may include, for example, accessing adaptive streaming information for a multimedia content segment, determining available access bandwidths for a plurality of video tracks and a plurality of audio tracks identified by the adaptive streaming information, selecting one of a plurality of candidate track pairings identified by the adaptive streaming information based on the available access bandwidths, obtaining video content of the multimedia content segment via a video track of the selected track pairing, and obtaining audio content of the multimedia content segment via an audio track of the selected track pairing. Other embodiments are disclosed.

Abstract: The present disclosure relates to an ER protein regulator compound represented by formula (I) and use thereof. LIN in the compound represented by formula (I) is a linker; ULM is a small-molecule ligand of VHL or CRBN protease having a ubiquitylation function; and group X is CH2, O or NH, and group X is covalently linked to ULM by means of the linker LIN. The designed and synthesized compounds of the present disclosure have wide pharmacological activity, has the function of regulating ER protein and inhibiting the activity of tumors, and can be used for preventing and/or treating diseases and disorders associated with estrogen receptors, or related tumor treatment.

Abstract: A method by which a base station transmits a signal on the basis of an antenna array in a wireless communication system, according to an embodiment of the present invention, comprises the steps of: determining a multi-rank beam in consideration of (i) positions of a plurality of terminals and (ii) positions of null points of a beam generated through the antenna array; and transmitting signals to the plurality of terminals by using the multi-rank beam. The antenna array may be based on a three-dimensional shape having omnidirectional symmetry, and the positions of the null points and the positions of the plurality of terminals may be configured on the basis of a polar coordinate system using the center of the antenna array as an origin point.

Abstract: Described are tracer eluting proppants, such as proppants that have polymeric coatings on them that include tracers, such as a fluorescent dye. The tracer eluting proppants can comprise proppant particles coated with a polymeric coating that can elute tracer under some, but not all conditions. For example, the tracer can be eluted at elevated temperature, pH, and/or salinity conditions, but not elute at lower temperature, pH, and/or salinity conditions. Methods of making and using tracer eluting proppants are also disclosed, including methods for characterizing subterranean reservoirs.

Abstract: The present disclosure compounds of the formulae: wherein the variables are defined herein, as well as pharmaceutical compositions thereof. The present disclosure also provides methods for the use of said compounds and/or pharmaceutical compositions, such as in the treatment of cancer.

Abstract: Systems, methods and apparatus for Shear TUrbulence Resuspension Mesocosm (STURM) tanks, with high instantaneous bottom shear stress and realistic water column mixing. The tanks can be programmed to produce tidal or episodic sediment resuspension for extended time periods, over muddy sediments with a variety of infaunal benthic organisms. A resuspension paddle produces substantially uniform bottom shear stress across the sediment surface while gently mixing a 1 m deep overlying water column. The STURM tanks can be programmed to different magnitudes, frequencies, and durations of bottom shear stress and thus resuspension with proportional water column turbulence levels over a wide range of mixing settings for benthic-pelagic coupling experiments.

Abstract: An augmented reality system for providing depth perspective includes a sensor system that provides spatial data of objects in a surrounding environment of a user. A computer processor system calculates spatial information of the objects from the spatial data received the sensor system. The computer processor system determines a depth-to-color mapping in which distance of objects from the user is mapped to a predetermined viewable representation. The system also includes a head mountable display that displays the depth-to-color mapping to the user. Characteristically, distances of the objects from the user are rendered to allow at least partial viewability of the object by the user. A method utilizing the augmented reality system is also provided.

Abstract: Systems, apparatus and methods for producing objects with cryogenic 3D printing with controllable micro and macrostructure with potential applications in tissue engineering, drug delivery, and the food industry. The technology can produce complex structures with controlled morphology when the printed 3D object is immersed in a liquid coolant, whose upper surface is maintained at the same level as the highest deposited layer of the object. This ensures that the computer-controlled process of freezing is controlled precisely and already printed frozen layers remain at a constant temperature. The technology controls the temperature, flow rate and volume of the printed fluid emitted by the dispenser that has X-Y positional translation and conditions at the interface between the dispenser and coolant surface. The technology can also control the temperature of the pool of liquid coolant and the vertical position of the printing surface and pool of coolant liquid.

Abstract: A sterilizable connector may include a sterilization fluid reservoir to provide a sterilization fluid. The sterilizable connector may include a connector. The connector may include a first end to receive a first tube to connect to a medical device (e.g., directly or via one or more intervening components). The connector may include a second end to receive a second tube to connect to a patient (e.g., directly or via one or more intervening components). The connector may include a body to couple the first end to the second end to enable fluid transfer between the first tube and the second tube. The connector may include a body opening to couple to the sterilization fluid reservoir. The sterilizable connector may include a sterilization fluid injector to inject the sterilization fluid from the sterilization fluid reservoir to the connector.

Abstract: An object of the present invention is to provide a method for producing T cells or NK cells, a culture medium for culturing T cells or NK cells, a method for culturing T cells or NK cells, a method for maintaining the undifferentiated state of undifferentiated T cells, and a growth promoter for T cells or NK cells, which are capable of efficiently proliferating T cells or NK cells and maintaining the state of the cells (for example, undifferentiated property). The present invention relates to a method for producing T cells or NK cells including culturing T cells or NK cells in a culture medium containing a bisbenzylisoquinoline alkaloid represented by formula (X-1) or formula (X-2) or a compound resulting from cleavage of one ether bond thereof or a pharmaceutically acceptable salt thereof, and the like.

Abstract: Disclosed is linoleic acid isomerases and their application in production of conjugated linoleic acid, which belongs to the technical fields of protein engineering and microbial engineering. The linoleic acid isomerase derived from Bifidobacterium is used to produce the conjugated linoleic acid. The recombinant E. coli containing the linoleic acid isomerase of the invention is added into a reaction system containing linoleic acid and react for 3 h to produce conjugated linoleic acids. The conversion rate of the conjugated linoleic acid of the invented method ranges from 12.1% to 42.1%, and the percentage of cis9, trans11-CLA in the conjugated linoleic acid can reach 84.3% to 89.1%. The invention provides a method for using microorganisms to produce conjugated linoleic acids with high safety and yield where cis9, trans11-CLA isomer is the major form in the conjugated linoleic acid products.

Abstract: An apparatus includes a solution including a metallic compound, a surfactant, and an acid. The solution is substantially colorless. A container holds the solution.

Abstract: A device adapted to be secured to the foot of a user includes one or more vibration actuators configured to provide vibrations to the user's foot, one or more force or acceleration sensors configured to sense forces or acceleration exerted by the user's foot, and a controller configured to operate the vibration actuators in a continuous mode to provide intermittent vibration to the user's foot independent of information sensed by the force or acceleration sensors. The vibration includes a first period of continuous vibration followed by a second period of no vibration followed by a third period of continuous vibration. The device may also be configured to operate in a feedback mode.

Abstract: Disclosed herein are libraries of reporter nucleic acids for functional regulatory elements as well as methods and kits for constructing and using such libraries. Exemplary libraries, methods, and kits can be used for high-throughput detection, identification, and/or quantitation of functional regulatory elements.

Abstract: The disclosure relates to a method and system for AC line distance protection in AC/DC hybrid power grid, and storage medium.

Abstract: This disclosure relates to variant AAVrh 10 particles engineered to escape host neutralizing antibodies but retain or improve transduction efficiency, and their use as gene delivery vehicles.

Abstract: The present invention is related to the electronic device and learning method for learning of low complexity artificial intelligence model based on selecting dynamic prediction confidence threshold.

Abstract: The present application relates to a method for manufacturing a red blood cell-shaped nanostructure and a red blood cell-shaped nanostructure manufactured by the manufacturing method thereof. More specifically, the present application relates to a method for manufacturing a red blood cell-shaped nanostructure using a multi-fluid electrospray method including multiple nozzles, and a red blood cell-shaped nanostructure manufactured by the manufacturing method thereof.