Abstract: Methods and apparatuses for providing biometric authentication of a test user using a registration process where a reference data sample representative of one or more biometric attributes of a reference user is used to train a plurality of neural networks to achieve a target output. The weights that achieve this in the plurality of neural networks may be stored on a user device as a first data set. A second data set representative of one or more biometric attributes may be obtained from the test user using the authentication device or received from the user device. The first data set may be received by the authentication device and used as weights in an artificial neural network and the second data set may be used as inputs. The output of the neural network may determine a degree of correlation between the reference user and the test user to be authenticated.
Abstract: The invention is directed to compositions of cell aggregates and methods for making and using the cell aggregates where the aggregates comprise cells that are not embryonic stem cells but can differentiate into cell types of at least two of ectodermal, undo dermal, and mesodermal embryonic germ layers, e.g., stem cells.
Type:
Grant
Filed:
May 7, 2013
Date of Patent:
April 9, 2019
Assignees:
Regents of the University of Minnesota, Katholieke Universiteit Leuven
Inventors:
Wei-Shou Hu, Kartik Subramanian, Catherine M. Verfaillie
Abstract: A drill guidance device, a method to control a trajectory of a drill, and a non-transitory computer readable medium that determine the corrected drill angle and send an output signal to a drill controller configured to control an angle of a drill. The corrected drill angle is determined by at least one of a slant angle data and a formation property data received from a sensor device. The drill guidance device, the method to control a trajectory of a drill, and the non-transitory computer readable medium can be implemented in a measuring while drilling model to provide live guidance during a drilling operation or a predictive model to plan prior to the start of a drilling operation. The corrected drill angle is acted upon by a drill controller to maximize the productivity of an oil reservoir.
Type:
Grant
Filed:
March 9, 2018
Date of Patent:
April 9, 2019
Assignee:
King Fahd University of Petroleum and Minerals
Inventors:
Mohamed Hassan Awadh, Sami Abdulaziz Alnuaim
Abstract: A method of amplifying a phase shift, comprises: receiving an input signal in response to an output signal; generating a reference signal; varying a modulation of at least one of the signals such that a ratio between modulation amplitudes of the input and reference signals is at least 0.9 and at most 1.1, and a phase difference between the reference and the input signals is from about 0.9 pi to about 1.1 pi; forming an output signal which comprises a sum of the reference and input signals, following the variation; and filtering the output signal by a bandpass filter to form a filtered output signal, wherein a bandwidth of the bandpass filter is selected such that XG<0.1, wherein X is a noise fluctuation average of the filtered output signal, and G is an expected amplification factor of a phase shift between the input and the reference signals.
Type:
Grant
Filed:
October 6, 2016
Date of Patent:
April 9, 2019
Assignee:
Ariel-University Research and Development Company Ltd.
Abstract: The present invention provides methods for treating, preventing or reducing the severity of cerebral malaria. The methods of the present invention comprise administering to a subject in need thereof a therapeutically effective amount of a pharmaceutical composition comprising a modified angiopoietin molecule such as AngF1-Fc-F1.
Type:
Grant
Filed:
April 10, 2018
Date of Patent:
April 9, 2019
Assignees:
Regeneron Pharmaceuticals, Inc., University Health Network
Inventors:
Lisa Arleen Purcell Ngambo, Sarah J. Higgins, Kevin C. Kain
Abstract: The present disclosure provides a method for producing organic compounds, such as esters, from an organic feedstock that includes at least one of a biopolymer or a lipid. The method includes heating the feedstock in the presence of a solid catalyst, such as a solid, inorganic Lewis acid catalyst, and reaction medium that includes an alcohol. At least certain ester products have an ester group corresponding to a substituent of the alcohol.
Type:
Grant
Filed:
August 26, 2016
Date of Patent:
April 9, 2019
Assignee:
Board of Regents of the Nevada System of Higher Education, on Behalf of the University of Nevada, Reno
Abstract: The compound 3,3,3-trifluoro-N-((1,4-trans)-4-((3-((S)-2-methylmorpholino)-IH-pyrazolo[3,4-d]pyrimidin-6-yl)amino)cyclohexyl)propane-1-sulfonamide having the Formula (I) or a salt thereof, its opposite enantiomer, compositions comprising the compound and its use in the treatment or prevention of leishmaniasis, particularly visceral leishmaniasis.
Type:
Grant
Filed:
January 21, 2016
Date of Patent:
April 9, 2019
Assignees:
GlaxoSmithKline Intellectual Property Development Limited, University of Dundee
Inventors:
Timothy James Miles, Michael George Thomas
Abstract: A binding registration method includes: an SDN controller receiving a first bearer message that is forwarded by a first MAG in multiple MAGs and that carries a first L2 attach request message; sending, to each of the first MAG and an LMA, a message for establishing a tunnel between the first MAG and the LMA; sending, to each of the first MAG and the LMA, a message for adjusting a flow entry of an MN; configuring an HNP(s) for the MN, and encapsulating the HNP(s) into an RA message; and sending the RA message to the first MAG.
Type:
Grant
Filed:
November 23, 2016
Date of Patent:
April 9, 2019
Assignees:
Huawei Technologies Co., Ltd., University of Science and Technology of China
Inventors:
Kaiping Xue, Yizhen Wu, Dan Ni, Fang Yu
Abstract: The present invention provides compositions that include an extract of human feces, and methods for using such compositions, including methods for replacing or supplementing or modifying a subject's colon microbiota, and methods for treating a disease, pathological condition, and/or iatrogenic condition of the colon.
Type:
Grant
Filed:
June 19, 2017
Date of Patent:
April 9, 2019
Assignee:
Regents of the University of Minnesota
Inventors:
Michael J. Sadowsky, Alexander Khoruts, Alexa R. Weingarden, Matthew J. Hamilton
Abstract: Disclosed is a system and method for the combustion of biomass material employing a swirling fluidized bed combustion (SFBC) chamber, and preferably a second stage combustion carried out in a cyclone separator. In the combustion chamber, primary air is introduced from a bottom air box that fluidizes the bed material and fuel, and staged secondary air is introduced in the tangential direction and at varied vertical positions in the combustion chamber so as to cause the materials in the combustion chamber (i.e., the mixture of air and particles) to swirl. The secondary air injection can have a significant effect on the air-fuel particle flow in the combustion chamber, and more particularly strengthens the swirling flow, promotes axial recirculation, increases particle mass fluxes in the combustion chamber, and retains more fuel particles in the combustion chamber. This process increases the residence time of the particle flow.
Abstract: Methods of forming antimicrobial resin compositions comprising silver nanoparticles are disclosed, wherein the resin compositions that are generated exhibit lower initial color, reduced color shift upon storage and reduced levels of spontaneous polymerization. Such methods generally comprise: combining a silver-containing material with a self-cure and dual-cure base resin in situ wherein the base resin does not contain a catalytic amine; and adding a catalytic resin to the mixture of the resin and silver-containing material in order to form the final cured resin. Antimicrobial polymeric materials formed by said methods are also disclosed.
Type:
Grant
Filed:
October 2, 2014
Date of Patent:
April 9, 2019
Assignee:
The Board of Regents of the University of Texas System
Abstract: Disclosed herein are compositions comprising lopinavir alone or in combination with ritonavir for use as a medicament in the treatment of cancer or benign proliferative disorders (warts) or in the prevention of the development of cancer. Pharmaceutical compositions formulated for topical application comprising a therapeutically effective amount of lopinavir or a therapeutically effective amount lopinavir and ritonavir in a pharmaceutically acceptable vehicle are also provided. Also disclosed are methods of treating a patient having an HPV related dysplasia of the cervix comprising administering to said patient a therapeutically effective dose of the disclosed pharmaceutical compositions.
Abstract: The present invention relates to a tandem organic light-emitting element, more particularly to a tandem organic light-emitting element which may decrease a driving voltage in a driving region of a charge generation layer by sequentially laminating an electronics layer, which is doped with a metal dopant, and an electronics layer, which is doped with an organic dopant, on one side of the charge generation layer, thereby having increased power efficiency and life span.
Type:
Grant
Filed:
January 5, 2016
Date of Patent:
April 9, 2019
Assignees:
Corning Precision Materials Co., Ltd., University-Industry Cooperation Group of Kyung Hee University
Inventors:
Hyung Seok Lee, Kwang Je Woo, Jang Dae Youn, Jang Hyuk Kwon, Young Hoon Son
Abstract: An autothermal reforming catalytic structure for generating hydrogen gas from liquid hydrocarbons, steam and an oxygen source. The autothermal reforming catalytic structure includes a support structure and nanosized mixed metal oxide particles dispersed homogenously throughout the support structure.
Type:
Grant
Filed:
April 1, 2016
Date of Patent:
April 9, 2019
Assignees:
Saudi Arabian Oil Company, The University of Queensland
Inventors:
Jorge N. Beltramini, Moses O. Adebajo, Joao Carlos Diniz Da Costa, Gao Qing Lu, Thang V. Pham, Sai P. Katikaneni
Abstract: The present invention is about the design and manufacturing method of constructing nano-structured lattices. The design of the four periodic two-dimensional lattices (hexagonal, triangulated, square and Kagome) is described; and the process of making nano-structured lattices is outlined in the present invention.
Abstract: A device for studying protein conformation transformation can include a macroscopic substrate, and chaperonin proteins bound to the substrate, each chaperonin protein being capable of binding to a protein of interest during or after undergoing protein conformation transformation. The device may also include the proteins of interest bound to the substrate, where the substrate is included in a label-free assay system. A method of studying protein conformation transformation can include: providing a macroscopic substrate bound with the chaperonin protein and immersing the chaperonin protein in a study composition having the protein of interest, or include providing a macroscopic substrate bound with the protein of interest; and immersing the protein in a study composition having the chaperonin. Such a method can be done with and without a potential stabilizer in order to determine whether the potential stabilizer stabilizes the protein of interest.
Abstract: The present disclosure provides compositions, kits, genetically modified cells, non-human transgenic organisms, and methods for binding and/or cleaving a single stranded target nucleic acid. A method of cleaving includes contacting a single stranded target nucleic acid with (e.g., introducing into a cell) a subject argonaute (Ago) polypeptide and a guide RNA (e.g., having a 5?-OH). In some embodiments, a subject Ago polypeptide includes an amino acid sequence having 70% or more sequence identity with amino acids 282-430 and/or 431-639 of the Marinitoga piezophila argonaute (MpAgo) protein set forth in SEQ ID NO: 1. The present disclosure provides variant Ago polypeptides; and methods of use of same.
Type:
Grant
Filed:
April 9, 2015
Date of Patent:
April 9, 2019
Assignee:
The Regents of the University of California
Inventors:
Jennifer A. Doudna, Emine Kaya, Kilian R. Knoll
Abstract: Embodiments of the present disclosure are directed towards methods for preparing mixed-metal oxide particles by heating adamantane-intercalated layered double-hydroxide (LDH) particles at a reaction temperature of from 400° C. to 800° C. to form mixed-metal oxide particles. The adamantane-intercalated LDH particles have a general formula [M1-xAlx(OH)2](A)x.mH2O, where x is from 0.14 to 0.33, m is from 0.33 to 0.50, M is chosen from Mg, Ca, Co, Ni, Cu, or Zn, and A is adamantane carboxylate, and an aspect ratio greater than 100. The aspect ratio is defined by the width of an adamantane-intercalated LDH particle divided by the thickness of the adamantane-intercalated LDH particle. The mixed-metal oxide particles comprise a mixed-metal oxide phase containing M, Al or Fe, and carbon.
Type:
Grant
Filed:
March 8, 2017
Date of Patent:
April 9, 2019
Assignees:
Saudi Arabian Oil Company, Durham University
Inventors:
Manohara Gudiyor Veerabhadrappa, Hugh Christopher Greenwell, Gasan Selman Alabedi, John Adrian Hall, Andrew Whiting
Abstract: Articles are provided comprising a substrate and a coating. The coating comprises a polyelectrolyte complex having surface roughness. The polyelectrolyte complex has a thickness of at least 10 micrometers and a roughness of at least 1 micrometer.
Type:
Grant
Filed:
February 2, 2015
Date of Patent:
April 9, 2019
Assignee:
The Florida State University Research Foundation, Inc.