Abstract: Systems and methods for monitoring an animal include receiving a plurality of biological parameters of the animal from a plurality of biological sensors, receiving location parameters of the animal from at least one location sensor, receiving weather parameters corresponding to ambient weather conditions proximate the animal from at least one ambient weather sensor, and comparing at least one of the parameters generated by the sensors with data representing at least one signature corresponding to the animal to determine if there is an irregular parameter. In response to an irregular reading/parameter being identified, then determining if the identified irregular parameter is related to a health condition of the animal and if the identified irregular parameter is not related to the health condition of the animal, then determining if the identified irregular parameter is related to an illegal activity.
Type:
Grant
Filed:
December 20, 2017
Date of Patent:
January 18, 2022
Assignee:
Khalifa University of Science and Technology
Abstract: According to the present disclosure, an apparatus for real-time object detection in an image captured by an unmanned aerial vehicle (UAV) including an image splitter configured to receive an input image and split the input image into a left image and a right image; and an object detector configured to detect an object from each of the left image and the right image provided from the image splitter is provided.
Type:
Grant
Filed:
December 12, 2019
Date of Patent:
January 18, 2022
Assignee:
KWANGWOON UNIVERSITY INDUSTRY-ACADEMIC COLLABORATION FOUNDATION
Inventors:
Seong Kyun Han, Ji Sang Yoo, Soon Chul Kwon
Abstract: Disclosed herein are therapeutic constructs including a delivery particle, at least one mitotic kinase inhibitor, and at least one immune checkpoint inhibitor. Also disclosed are therapeutic constructs including a mitotic kinase inhibitor, an immune checkpoint inhibitor, and a chemical linker. These therapeutic constructs cause cancer death by both therapeutic and immune effects and promote targeted delivery of more therapeutics to the surviving cancer cells in a positive feed-back loop. They enhance therapeutic index of free drugs and can be used intratumorally or systemically. This strategy can treat broad cancer types and is particular useful for cancer without obvious receptors for cancer-targeted delivery of otherwise toxic therapeutics.
Type:
Grant
Filed:
September 16, 2020
Date of Patent:
January 18, 2022
Assignees:
Oregon Health & Science University, PDX Pharmaceuticals, Inc.
Abstract: A semiconductor memory device includes a memory cell array including one or more memory cells each coupled between a wordline and a bitline, a sense amplifier configured to amplify a voltage of a global wordline, a wordline decoder including a plurality of wordline switches coupling the wordline and the global wordline, and a control circuit configured to control the wordline decoder and the sense amplifier.
Type:
Grant
Filed:
June 25, 2019
Date of Patent:
January 18, 2022
Assignees:
SK hynix Inc., Seoul National University R&DB Foundation
Inventors:
Hyungrok Do, Hong Seok Choi, Deog-Kyoon Jeong
Abstract: The invention generally relates to a carbon-based boron removal medium with hydroxyl group and amine group, and in particular, to a method for forming the carbon-based boron removal medium. In various embodiments, nitrogen-doped (“N-doped”) graphene oxide is synthesized by a simple two-step process: (1) oxidation of graphite to graphene oxide, and (2) nitrogen-doping (“N-doping”) the graphene oxide to form the amine group. The resultant N-doped graphene oxide can efficiently remove boron from aqueous solutions. The invention also generally relates to a boron sensing medium and its use in conductometric measurement techniques to detect and measure the amount of boron present in aqueous solutions.
Type:
Grant
Filed:
March 30, 2021
Date of Patent:
January 18, 2022
Assignee:
SINGAPORE UNIVERSITY OF TECHNOLOGY AND DESIGN
Abstract: A method for detecting an artifact of a blood pressure signal includes measuring consecutive signals of blood pressure in real time, dividing the consecutive signals into a plurality of unit waveforms by searching systolic starting points and peak points from the measured signals, determining two outputs by applying N consecutive unit waveforms among the plurality of unit waveforms as an input to a deep belief network (DBN), and determining whether the signal is an artifact or a normal signal by using the two determined outputs. According to the present disclosure, it is possible to minimize various false alarms of bio-signal streams which are measured in real time by automatically eliminating ABP artifacts using a deep belief network (DBN) which is one of deep neural network (DNN) models capable of learning causes and shapes of various types of artifacts together.
Type:
Grant
Filed:
September 5, 2018
Date of Patent:
January 18, 2022
Assignee:
Korea University Research and Business Foundation
Abstract: The image decoding method according to the present invention comprises the steps of: determining the availability of a block adjacent to a current block; configuring a merge candidate list for the current block on the basis of the result of the determined availability; and performing motion compensation for the current block on the basis of the merge candidate list, wherein the step of determining availability comprises the steps of inducing block availability information on the adjacent block and inducing the availability of motion information on the adjacent block, and the step of determining the availability of the adjacent block is such that when there is more than one adjacent block, the availability of adjacent blocks can be determined in accordance with a predetermined order restriction.
Type:
Grant
Filed:
October 24, 2019
Date of Patent:
January 18, 2022
Assignees:
Electronics and Telecommunications Research Institute, UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY
Inventors:
Hui Yong Kim, Sung Chang Lim, Jin Soo Choi, Jin woong Kim, Gwang Hoon Park, Kyung Yong Kim
Abstract: Some embodiments relate to genetically engineered bacterial strains for modulation of levels of the bacterial metabolite 4-ethylphenol (4EP) and its sulfated form, 4-ethylphenyl sulfate (4EPS). In some embodiments, the bacteria reduce or inhibit production of 4EP or 4EPS in the gut of a subject. The bacteria can ameliorate, delay the onset or reduce the likelihood of one or more symptoms associated with anxiety and/or autism spectrum disorder (ASD) in the subject.
Type:
Grant
Filed:
February 13, 2018
Date of Patent:
January 18, 2022
Assignees:
CALIFORNIA INSTITUTE OF TECHNOLOGY, THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Inventors:
Brittany D. Needham, Sarkis K. Mazmanian, Gil Sharon, Masanori Funabashi, Michael A. Fischbach, Elaine Y. Hsiao, Paul H. Patterson
Abstract: A superconducting wire according to the present disclosure includes: a base material; a superconductor layer formed on each of the respective surfaces of the base material; and a conductive protection layer formed on each of the surfaces of the respective superconductor layers. The thickness of each of the conductive protection layers is 5% or less of the skin depth when a high-frequency current flows through the superconducting wire. The material for forming the conductive protection layer may be, for example, silver.
Abstract: A method for obtaining one or more images of a sample using a microscope includes dividing, using a reverberation cavity, a first one of a plurality of laser pulses into a plurality of sequential sub-pulses, each of the plurality of sequential sub-pulses having a power that is less than a previous one of the plurality of sequential sub-pulses, directing, using the one or more lenses of the microscope, the plurality of sequential sub-pulses onto a portion of the sample to generate a plurality of signals, each of the plurality of signals being associated with a different depth within the sample, and detecting the plurality of signals from the sample to generate one or more images of at least a portion of the sample.
Type:
Grant
Filed:
April 23, 2020
Date of Patent:
January 18, 2022
Assignee:
TRUSTEES OF BOSTON UNIVERSITY
Inventors:
Jerome Charles Mertz, Devin Robert Beaulieu, Thomas Gary Bifano
Abstract: A method of using data-driven predictive modeling to predict and classify battery cells by lifetime is provided that includes collecting a training dataset by cycling battery cells between a voltage V1 and a voltage V2, continuously measuring battery cell voltage, current, can temperature, and internal resistance during cycling, generating a discharge voltage curve for each cell that is dependent on a discharge capacity for a given cycle, calculating, using data from the discharge voltage curve, a cycle-to-cycle evolution of cell charge to output a cell voltage versus charge curve Q(V), generating transformations of ?Q(V), generating transformations of data streams that include capacity, temperature and internal resistance, applying a machine learning model to determine a combination of a subset of the transformations to predict cell operation characteristics, and applying the machine learning model to output the predicted battery operation characteristics.
Type:
Grant
Filed:
October 16, 2018
Date of Patent:
January 18, 2022
Assignees:
The Board of Trustees of the Leland Stanford Junior University, Massachusetts Institute of Technology
Inventors:
Kristen Ann Severson, Richard Dean Braatz, William C. Chueh, Peter M. Attia, Norman Jin, Stephen J. Harris, Nicholas Perkins
Abstract: This invention relates to the detection and quantification of D-dimer levels in a sample derived from a patient having or suspected of having periprosthetic joint infection (PJI) and subsequent diagnosis of PJI.
Abstract: An object of the present invention is to provide an agent for preventing or treating a fat-associated disease and/or inflammation. The present invention provides an agent for preventing or treating a fat-associated disease and/or inflammation, the agent comprising a Faecalibacterium bacterium or a processed product thereof.
Type:
Grant
Filed:
June 15, 2018
Date of Patent:
January 18, 2022
Assignees:
Biofermin Pharmaceutical Co., Ltd., Public University Corporation Yokohama City University
Abstract: A system and method for determining a sentiment, a gender and an age group of a subject in a video while the video is being played back. The video is separated into visual data and audio data, the video data is passed to a video processing pipeline and the audio data is passed to both an acoustic processing pipeline and a textual processing pipeline. The system and method performs, in parallel, a video feature extraction process in the video processing pipeline, an acoustic feature extraction process in the acoustic processing pipeline, and a textual feature extraction process in the textual processing pipeline. The system and method combines a resulting visual feature vector, acoustic feature vector, and a textual feature vector into a single feature vector, and determines the sentiment, the gender and the age group of the subject by applying the single feature vector to a machine learning model.
Type:
Grant
Filed:
October 2, 2019
Date of Patent:
January 18, 2022
Assignee:
King Fahd University of Petroleum and Minerals
Inventors:
El-Sayed M. El-Alfy, Sadam Hussein Al-Azani
Abstract: A computer-implemented method and system for determining a path arrangement of an infrastructure link. The method includes receiving one or more inputs each indicative of a constraint; and processing the one or more inputs and a set of data based on a path arrangement determination model. The set of data includes data representing one or more factors affecting the path arrangement. The method also includes determining, based on the processing, the path arrangement of the infrastructure link.
Type:
Grant
Filed:
June 1, 2020
Date of Patent:
January 18, 2022
Assignee:
City University of Hong Kong
Inventors:
Moshe Zukerman, Zengfu Wang, Qing Wang, William Moran, Xinyu Wang, Elias Tahchi, Fu Chu Leung
Abstract: The present disclosure provides antibodies that specifically bind to Mer Tyrosine Kinase (MERTK) (e.g., human MERTK, or both human and mouse MERTK) and compositions comprising such antibodies, wherein said antibody agonizes MERTK signaling on endothelial cells. The present disclosure also provides methods for treating cancer, by administering an antibody that specifically binds to MERTK and agonizes MERTK signaling on endothelial cells.
Type:
Grant
Filed:
January 24, 2019
Date of Patent:
January 18, 2022
Assignee:
The Rockefeller University
Inventors:
Sohail Tavazoie, Nils Halberg, Masoud Tavazoie
Abstract: Described herein various PCR based assays that can detect H. penaei and/or V. parahaemolyticus that causes AHPND in a nucleic acid sample obtained from one or more shrimp. In some aspects, the PCR based assays can detect one or more of the following genes: the flgE gene from H. penaei, the shrimp 18s rRNA gene, the shrimp beta actin gene from shrimp, a bacterial 16S rRNA gene from bacteria (any type of bacteria) the Vibrio pirA gene, and the Vibrio pirB gene. The assays described herein can be single assays or can be multiplexed such that more than one gene and/or more than one bacterial species can be detected in a single reaction. Other compositions, compounds, methods, features, and advantages of the present disclosure will be or become apparent to one having ordinary skill in the art upon examination of the following drawings, detailed description, and examples.
Type:
Grant
Filed:
August 16, 2019
Date of Patent:
January 18, 2022
Assignee:
Arizona Board of Regents on Behalf of the University of Arizona
Inventors:
Luis F. Aranguren Caro, Arun Dhar, Roberto Cruz Flores
Abstract: The present disclosure provides antibodies that specifically bind to botulinum neurotoxins (e.g., BoNT/A, BoNT/B, BoNT/C, BoNT/D, BoNT/E, BoNT/F, BoNT/G, etc.) and the epitopes bound by those antibodies. The antibodies and derivatives thereof that specifically bind to the neutralizing epitopes provided herein can be used to neutralize botulinum neurotoxin and are therefore also useful in the treatment of botulism.
Type:
Grant
Filed:
March 9, 2020
Date of Patent:
January 18, 2022
Assignee:
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Inventors:
James D. Marks, Maria Consuelo Garcia Rodriguez
Abstract: A device for manipulating an incident acoustic wave to generate an acoustic output is described wherein the device comprises a plurality of unit cells arranged into an array, at least some of said unit cells being configured to introduce time delays to an incident acoustic wave at the respective positions of the unit cells within the array of unit cells, such that said plurality of unit cells define an array of time delays to thereby define a spatial delay distribution for manipulating an incident acoustic wave to generate an acoustic output. The array of time delays may be re-configured to vary the spatial delay distribution of the device in order to generate different acoustic outputs. Also described are methods for designing or configuring such devices.
Type:
Grant
Filed:
December 18, 2020
Date of Patent:
January 18, 2022
Assignee:
The University of Sussex
Inventors:
Sriram Subramanian, Gianluca Memoli, Bruce Drinkwater, Mihai Caleap, Deepak Ranjan Sahoo